Lead actress Lee Remick and co-star Patty Duke had both received Oscar nominations - the sole one for each actress - at 35th Annual Academy Awards (1963), Remick being best actress nominated for I giorni del vino e delle rose (1962) and Duke winning best supporting actress for Anna dei miracoli (1962) (the latter film's star Anne Bancroft winning best actress over Remick).
Patty Duke's signature role of Helen Keller, which she played in Anna dei miracoli (1962), would be played by her "Women's Room" co-star Mare Winningham in Helen Keller: The Miracle Continues (1984).
Lee Remick's second husband, British producer Kip Gowans, worked with Lee on a number of TV movies including Donne (1980), and Lo specchietto retrovisore (1984)