In the musical drama, Io amo (1946), Peg La Centra dubbed the singing voice of Ida Lupino. In this film, from the following year, Miss Lupino did her own singing.
Ida Lupino was paid $95,000 for her role.
The scenes in the roadhouse's bowling alley were shot at a real bowling alley which was located near the studio.
In a 1969 interview, director Jean Negulesco recalled that when Fox studio chief Darryl F. Zanuck gave him the assignment to direct 'Road House', Zanuck told him, "This is a bad script. Three directors have refused it. They don't know what they're doing, because basically it's quite good. Remember those pictures we used to make at Warner Bros., with Pat O'Brien and Jimmy Cagney, in which every time the action flagged we staged a fight and every time a man passed a girl she'd adjust her stocking or something, trying to be sexy? That's the kind of picture we have to have with 'Road House.'"
"One for My Baby (And One More for the Road), (music by Harold Arlen, lyrics by Johnny Mercer and sung by Ida Lupino), was originally sung (and danced to) by Fred Astaire in Non ti posso dimenticare (1943).