In 1934, this film was condemned by the Catholic Legion of Decency.
The failure of the original copyright holder to renew the film's copyright resulted in it falling into public domain, meaning that virtually anyone could duplicate and sell a VHS/DVD copy of the film. Therefore, many of the versions of this film available on the market are either severely (and usually badly) edited and/or of extremely poor quality, having been duped from second- or third-generation (or more) copies of the film.
There is no time frame given, but Doc Silsby has a telephone and a car, which would make the film approximately contemporary.
Copyright MCMXXXIII is under the main title. That is 1933 in Roman Numerals.
The wanted poster on Gat Gans, with Wayne's picture, has him listed at 6'3" and 193#. That was Wayne's height and weight at the time.