49 premios ganados & 78 nominaciones
- 1997 Nominado American Comedy Award
- Funniest Supporting Actress in a Motion Picture
- 1994 Nominado American Comedy Award
- Funniest Actress in a Motion Picture (Leading Role)
- 1992 Ganador American Comedy Award
- Funniest Actress in a Motion Picture (Leading Role)
- 2007 Nominado Critics Choice Award
- Best Acting Ensemble
Se compartió con: Lindsay Lohan · Meryl Streep · Virginia Madsen · Tommy Lee Jones · Maya Rudolph · Kevin Kline · Garrison Keillor · Woody Harrelson · John C. Reilly
- 1994 Nominado CableACE
- Performance in a Comedy Special
- 2016 Nominado Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 2016 Nominado Golden Globe
- Best Performance by an Actress in a Motion Picture - Comedy or Musical
- 1994 Ganador Special AwardFor the ensemble cast.Se compartió con: Andie MacDowell · Bruce Davison · Jack Lemmon · Zane Cassidy · Julianne Moore · Matthew Modine · Anne Archer · Fred Ward · Jennifer Jason Leigh · Chris Penn · Joseph C. Hopkins · Josette Maccario · Lili Taylor · Robert Downey Jr. · Madeleine Stowe · Tim Robbins · Cassie Friel · Dustin Friel · Austin Friel · Tom Waits · Frances McDormand · Peter Gallagher · Jarrett Lennon · Annie Ross · Lori Singer · Lyle Lovett · Buck Henry · Huey Lewis · Danny Darst · Margery Bond · Robert DoQui · Darnell Williams · Michael Beach · Andi Chapman · Deborah Falconer · Susie Cusack · Charles Rocket · Jane Alden
- 1985 Nominado Golden Globe
- Best Performance by an Actress in a Motion Picture - Comedy or Musical
- 1978 Nominado Golden Globe
- Best Actress in a Motion Picture - Comedy or Musical
- 2006 Nominado Gotham Independent Film Award
- Best Ensemble Performance
Se compartió con: Woody Harrelson · Tommy Lee Jones · Garrison Keillor · Kevin Kline · Lindsay Lohan · Virginia Madsen · John C. Reilly · Maya Rudolph · Meryl Streep · L.Q. Jones · Sue Scott · Tim Russell
- 2023 Ganador Peabody Award
- Career Achievement Award
- 1976 Nominado Gold Medal
- Favorite Female Star
- 1975 Nominado Gold Medal
- Variety Star
- 2005 Nominado Actor
- Outstanding Performance by an Ensemble in a Drama Series
Se compartió con: Stockard Channing · Kristin Chenoweth · Dulé Hill · Allison Janney · Joshua Malina · Mary McCormack · Janel Moloney · Richard Schiff · Martin Sheen · John Spencer · Bradley Whitford
- 1993 Ganador Special Volpi CupSe compartió con: Andie MacDowell · Bruce Davison · Jack Lemmon · Zane Cassidy · Julianne Moore · Matthew Modine · Anne Archer · Fred Ward · Jennifer Jason Leigh · Chris Penn · Joseph C. Hopkins · Josette Maccario · Lili Taylor · Robert Downey Jr. · Madeleine Stowe · Tim Robbins · Cassie Friel · Dustin Friel · Austin Friel · Tom Waits · Frances McDormand · Peter Gallagher · Jarrett Lennon · Annie Ross · Lori Singer · Lyle Lovett · Buck Henry · Huey Lewis · Danny Darst
- 1974 Nominado WGA Award (TV)
- Best Written Variety Script
Se compartió con: Bob Illes · Rosalyn Drexler · Lorne Michaels · Richard Pryor · Jim Rusk · Herbert Sargent · James R. Stein · Jane Wagner · George Yanok · Ann Elder · Karyl Miller · Rod Warren
- 2015 Nominado DFCC
- Best Actress
Tied with Charlize Theron for Mad Max: Furia en el camino (2015) and Emily Blunt for Tierra de Nadie: Sicario (2015) in 4th place
- 2019 Ganador CinEuphoria
- Career - Honorary Award
- 2017 Ganador Voice Arts Award
- Life Time Achievement Icon Award
- 2007 Nominado Gold Derby Film Award
- Ensemble Cast
Se compartió con: Woody Harrelson · L.Q. Jones · Tommy Lee Jones · Garrison Keillor · Kevin Kline · Lindsay Lohan · Virginia Madsen · John C. Reilly · Maya Rudolph · Meryl Streep
- 2020 Ganador Queerty
- Woof Worthy Influencer
- 2003 Ganador Mark Twain Prize
- Mark Twain Prize for American Humor
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