The famous National Geographic cover of the Afghan girl whose eyes mesmerized the world and who was found years later makes a cameo in the film.
For a brief moment in the opening credits only the letters I and O are shown in the movie title. This gives "IOII". In binary the number 1011 translates as eleven which is an important number throughout the film.
Resurrection is a big theme throughout the movie, as Ian doesn't believe in it and Sofi does. The eye necklace Sofi wears is the eye of Horus, an Egyptian symbol for healing and resurrection.
One minute into the movie, Ian is sitting in front of his computer. The screen shows a picture that looks a bit like an eye. It is in fact a well known image of the so-called Cat's Eye Nebula, taken by NASA with the Hubble space telescope.
The date Salomina's eyes were scanned into the system at the community center was on 11-3-2013 which sums up to 11.