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Follows the adventures of a doctor in his hospital and with his friends and family.

A cowboy-boot wearing, ranching country doctor who makes house calls is lured to a sprawling metropolis by a slick lady friend and immediately finds himself neck-deep in culture shock. He begins work at a downtown medical clinic, and within a day he turns the clinic's administrative and medical procedures topsy-turvy.

Nate is forced to confront Gunny after he seems to be jeopardizing other officers' safety on the street by his actions. Clint diagnoses Gunny's secret, but Gunny forbids him from telling anyone about his condition, which could be helped by a radical surgical procedure. Derek's sponsored 'son' Vijay arrives from India and ends up living with the Hebert's and cooking wonderful Indian dishes. But he may not be all he appears to be. Lt. Doss' old girlfriend Rita, a Navy Seal, visits. Tippy feels inadequate, so she does something about it.

Dr. Crane leaves the clinic and makes trouble for Clint. Dr. Hebert gets bad news.

A couple comes to Clint seeking infertility treatments but Clint's diagnosis and medical advice surprise them. A rival clinic challenges the Westbury Clinic to a bowling match for their annual charity competition and our gang thinks they finally have a chance to win until Tippy joins the team. Nate and Beverly counsel an engaged couple and end up learning a thing or two about their own marriage.

Nate wonders if Beverly's food cravings are common. Richard Black tells everyone at Westbury that going corporate is a good idea, but problems are about to happen. Black continues his big lie. Only Clint smells a rat.

Amy Lynn tries to comfort a teen who has cystic fibrosis.

Shannon, Nancy's old college roommate, comes by the clinic complaining of feeling tired all the time. Nancy isn't happy to see her because Shannon dated all the boys. Clint runs tests on Shannon come back negative, that is until Clint runs a heavy metal toxicology screen to find out if arsenic is making her sick.

Clint helps a blind man by means of a corneal transplant, but his wife wonders if the world he sees will come up to his expectations. Dr. Crane is dismayed by the gratitude of a mobster whose life he saved.

Derek believes he has glaucoma because his blood pressure is too high and he might be losing his sight. Dr. Crane wants to know how Tippy comes up with the sayings that grace the board in the waiting room because he can't come up with any himself.

Clint treats a man with Asperger's Syndrome named John, He wants to lead a normal life but his mother is afraid that this would only cause him heartbreak. Clint and Nancy try to teach John how to overcome his fear of not having his mother to help him. Raul thinks that he is ready to be his own man after becoming interested in New York City messengers.

Nate tries to help a workaholic who is to busy to worry about his own health or to spend time with his family. When money disappears from a crime scene, Nate and his partner are investigated by Internal Affairs.

A "Stressology" Specialist helps the staff deal with a superhero who believes in his powers too much.

Friends of Nancy come to the clinic to meet Clint. They later have to make a decision that will affect their twins: they will need to decide whether to terminate one twin's life to save the other.

Clint becomes temporary caretaker for a street performer whose partner has become very ill. Dr. Crane considers running for city councilman and hires an image consultant.

Is Nancy ready to move on after the death of her mother? Tippy tries to set Nancy on a date with a young lawyer. Nancy grows closer to Clint, while he continues his relationship with Dr. Weston.

Dr. Crane tries to reconnect with his father whom he hasn't seen in 30 years.

Clint cares for a mother, father and son who are friends of Nancy but they seem to have a family secret. Nate and Beverly go to a spa with Derek and Nellie. Tippy starts a lunchtime errand business to buy Steven a special birthday present. Dr. Crane lobbies for a spot on a medical certification board.

Donny suddenly learns he has an inheritance. Clint tries to advise Donny on how to handle the money. Clint learns Donny's cousin Ray may try to keep him from getting the money. Raul learns how to handle an allowance.

Clint begins to suspect that another doctor is fraudulently admitting patient only to collect money from their insurance companies.

Nancy tries to save her father's store from being condemned. Nate learns that he needs to give a speech to new police officers. Derek tells Nate that a joke might be the best way to get over being nervous. Later, he learns that telling jokes doesn't seem to work very well.

Richard Black wants to make Westbury Clinic a part of his management team, but doing so Donna DeWitt agrees to performance evaluations. Black asks Dr. Crane to handle the cross evaluation of the nurses.

A model learns the risks of plastic surgery. Clint helps an associate cope with the loss of a child.

Clint delivers a baby in a cab. Later when the baby is critically ill, the father sues for malpractice. A man claiming to be Raul's father appears looking for money. Raul doesn't take to Beverly. Dr. Hebert learns that he will be a dad.

Clint must help Raul's band teacher cope with the news that he has ALS, Lou Gehrig's disease. Dr. Crane's college rival shows up at the clinic.