-Acoramidis increased sTTR early and significantly reduced intra-individual sTTR variability versus placebo (p<0.001), which is associated with reduced ACM, further reinforcing its differentiated profile in ATTR-CM ... .
To understand the prognostic importance of intraindividual variation in sTTR beyond mean-achieved sTTR levels ... Lower sTTR CVi Less sTTR intraindividual ... LandmarkAnalysis of ACM (M12-M30) by Mean sTTR Concentration and sTTR CVi ... + sTTR mean + sTTR CVi.
Zeke Topolosky, the Army’s program manager for the SBIR and STTR programs, said all the service had to do after the innovation efforts were shut down for six months was turn up the program instead of having to turn it back on.