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- Theatrical poster (en)
- Vito Scotti plays Maj. Alfredo Fortuno, Italian POW Senior Officer. Colonel Pyser tells Newman the Italian POWs are not to receive therapy: “If they hate their fathers, that’s all right with us.” (en)
- Gregory Peck plays Capt. Josiah J. Newman, M.D., MC, USAR, head of the neuro-psychiatric Ward 7 at the Colfax Army Air Field military hospital. (en)
- Bobby Darin plays Cpl. Jim Tompkins, USAAF, dealing with survivor’s guilt, he resists therapy, abusing alcohol to deal with a mind shattered by war experiences. He is antisocial and a disciplinary problem. (en)
- Robert Duvall plays Capt. Paul Cabots Winston, who is catatonic, overwhelmed with guilt for having evaded capture during the German occupation of a town. (en)
- Eddie Albert plays Col. Norval Algate Bliss, USAAF, a “brilliant military tactician,” evaluated for an underlying medical condition when he displays erratic behavior related to a small social faux pas. (en)
- Tony Curtis plays Cpl. Jackson 'Jake' Leibowitz, USAAF, de facto boss of the orderlies, a wheeler-dealer from New Jersey, who makes even Newman’s unconventional methods look prosaic. (en)
- Angie Dickinson plays 1st Lt. Francie Corum, NC, USAR, who thinks Newman asks her on a dinner date... until Newman asks her to transfer to Ward 7. (en)
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