bowtie2 wrapper does not quote argument values. This means, for example, if a sample name with a space is passed as --rg "SM:Sample A" it is parsed by the Perl wrapper properly, but passed to bowtie2-align as --rg SM:Sample A, which causes problems with the parsing.
Hi Lance,
Thank you for pointing this to us. We will fix the wrapper for the next release cycle.
thanks,
Val
Added the fix.