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Molecule of the Month
March 2026
Lenacapavir

A potent and long-acting drug that targets the HIV capsid

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Learn
PDB data help explain fundamental biology, biomedicine, bioengineering/biotechnology, and energy sciences
Feature Focus
Use PDB-101 resources to learn how researchers are using biology in industry
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The RCSB PDB Curricula provide authentic, hands-on teaching materials, individual and group activities and assessment suggestions
SciArt Galleries
Irving Geis (1908-1997) was a gifted artist who helped illuminate the field of structural biology with his iconic images. The Geis Digital Archive features many of his illustrations in the context of their molecular structures.

Images used with permission from the Howard Hughes Medical Institute (www.hhmi.org). All rights reserved.

Myoglobin Fold

Myoglobin

Collagen

Deoxyribonucleic Acid (DNA)

A-DNA

Immunoglobulin G (IgG)

Cytochrome c (unbound)

Z-DNA

Hemoglobin

Lysozyme (512)

Deoxyhemoglobin

DPG-Hemoglobin Complex

Carboxypeptidase A

Aspartate Transcarbamoylase (ATCase)

Induced Lac Repressor

Ribonuclease S

Myohemerythrin

Lac Repressor

B-DNA

Hemoglobin S

Tomato Bushy Stunt Virus (TBSV)

Lysozyme (488)

Oxyhemoglobin

TATA-Binding Protein (TBP)

Transfer Ribonucleic Acid (tRNA)

Crambin

DNA

Intermolecular Contacts in Hemoglobin S

Cytochrome c

Trypsin

Hemoglobin (1000)

The Molecular Landscapes by David S. Goodsell integrate information from structural biology, microscopy and biophysics to simulate detailed views of the molecular structure of living cells.

Illustrations are free for use under a CC-BY-4.0 license

SARS-CoV-2 and Neutralizing Antibodies

Poliovirus Neutralization

Model of a Mycoplasma Cell

Autophagy

Insulin Release

Insulin Action

Respiratory Droplet

Biosites: Nucleus

RecA and DNA

Immunological Synapse

Ebola Virus

Escherichia coli Bacterium

Kinetochore

SARS-CoV-2 mRNA Vaccine

Coronavirus

HIV-Infected Cell

Mycoplasma mycoides

Cellulose Synthase

Influenza Virus

Blood

Casein Micelle and Fat Globule in Milk

Red Blood Cell Cytoskeleton

Abiogenesis

Influenza Vaccine

Bacteriophage T4 Infection

Last Universal Common Ancestor

Biosites: Muscle

Myelin

Zika Virus

Excitatory and Inhibitory Synapses

JCVI-syn3A Minimal Cell

Biosites: Cytoplasm

Biosites: Basement Membrane

Collagen and Extracellular Matrix

Caulobacter Polar Microdomain

Biosites: Blood Plasma

Myoglobin in a Whale Muscle Cell

HIV Vaccine

CytoSkeleton

Transfer RNA and Gag Protein

HIV in Blood Plasma

Chloroplast

Biosites: Red Blood Cell

Phage-based COVID-19 Vaccine

Lipid Droplets

Measles Virus Proteins

Coronavirus Life Cycle

Escherichia coli

SARS-CoV-2 Fusion

Vascular Endothelial Growth Factor (VegF) Signaling