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WO2006105367A3 - Magnetically-labeled microparticles for oral drug delivery - Google Patents

Magnetically-labeled microparticles for oral drug delivery Download PDF

Info

Publication number
WO2006105367A3
WO2006105367A3 PCT/US2006/011832 US2006011832W WO2006105367A3 WO 2006105367 A3 WO2006105367 A3 WO 2006105367A3 US 2006011832 W US2006011832 W US 2006011832W WO 2006105367 A3 WO2006105367 A3 WO 2006105367A3
Authority
WO
WIPO (PCT)
Prior art keywords
magnetically
drug delivery
oral drug
labeled microparticles
intestines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/011832
Other languages
French (fr)
Other versions
WO2006105367A2 (en
Inventor
Jianjun Cheng
Omid C Farokhzad
Benjamin Teply
Robert S Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of WO2006105367A2 publication Critical patent/WO2006105367A2/en
Publication of WO2006105367A3 publication Critical patent/WO2006105367A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A pharmaceutically active agent is associated with a magnetic particle and formulated for oral administration. An externally imposed magnetic field retains the magnetic particle in the intestines, increasing the amount of the pharmaceutically active agent that passes from the intestines into the bloodstream.
PCT/US2006/011832 2005-03-30 2006-03-30 Magnetically-labeled microparticles for oral drug delivery Ceased WO2006105367A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66674005P 2005-03-30 2005-03-30
US60/666,740 2005-03-30

Publications (2)

Publication Number Publication Date
WO2006105367A2 WO2006105367A2 (en) 2006-10-05
WO2006105367A3 true WO2006105367A3 (en) 2006-12-28

Family

ID=37054160

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/011832 Ceased WO2006105367A2 (en) 2005-03-30 2006-03-30 Magnetically-labeled microparticles for oral drug delivery

Country Status (1)

Country Link
WO (1) WO2006105367A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1970705A1 (en) * 2007-03-15 2008-09-17 Koninklijke Philips Electronics N.V. Bead assisted analyte detection
WO2011119995A2 (en) 2010-03-26 2011-09-29 Cerulean Pharma Inc. Formulations and methods of use
US9165703B2 (en) * 2010-08-25 2015-10-20 Brown University Methods and systems for prolonged localization of drug delivery
WO2016210098A1 (en) 2015-06-24 2016-12-29 Board Of Regents, The University Of Texas System Dual assembly nanoparticles
WO2017210543A1 (en) * 2016-06-03 2017-12-07 Tamarisk Technologies Group Llc Compositions for oral administration of active agents

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4345588A (en) * 1979-04-23 1982-08-24 Northwestern University Method of delivering a therapeutic agent to a target capillary bed
US6004534A (en) * 1993-07-23 1999-12-21 Massachusetts Institute Of Technology Targeted polymerized liposomes for improved drug delivery

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4345588A (en) * 1979-04-23 1982-08-24 Northwestern University Method of delivering a therapeutic agent to a target capillary bed
US6004534A (en) * 1993-07-23 1999-12-21 Massachusetts Institute Of Technology Targeted polymerized liposomes for improved drug delivery

Also Published As

Publication number Publication date
WO2006105367A2 (en) 2006-10-05

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