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WO2006039077A3 - Host-guest enery-absorbing complex - Google Patents

Host-guest enery-absorbing complex Download PDF

Info

Publication number
WO2006039077A3
WO2006039077A3 PCT/US2005/031972 US2005031972W WO2006039077A3 WO 2006039077 A3 WO2006039077 A3 WO 2006039077A3 US 2005031972 W US2005031972 W US 2005031972W WO 2006039077 A3 WO2006039077 A3 WO 2006039077A3
Authority
WO
WIPO (PCT)
Prior art keywords
guest
host
energy
complex
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/031972
Other languages
French (fr)
Other versions
WO2006039077A2 (en
Inventor
Wenxi Huang
Steve Roth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aspira Womens Health Inc
Original Assignee
Ciphergen Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciphergen Biosystems Inc filed Critical Ciphergen Biosystems Inc
Priority to CA002582338A priority Critical patent/CA2582338A1/en
Priority to EP05798023A priority patent/EP1802961A4/en
Priority to JP2007534618A priority patent/JP2008514956A/en
Publication of WO2006039077A2 publication Critical patent/WO2006039077A2/en
Publication of WO2006039077A3 publication Critical patent/WO2006039077A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

The present invention provides an energy-absorbing EAM that is a host-guest complex formed between a molecular host and a guest that is an energy-absorbing molecule (EAM). Exemplary of EAMs of use in the invention are species that absorb energy from a photo-irradiation source and thereby contributes to desorption and ionization of analyte molecules in operative contact therewith. When the complex and analyte are components of a surface, the transfer of energy promotes both the ionization of the analyte and its desorption from the surface. Also provided are methods for using the complexes of the invention and methods of preparing surfaces and devices incorporating a complex or the invention.
PCT/US2005/031972 2004-09-29 2005-09-08 Host-guest enery-absorbing complex Ceased WO2006039077A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002582338A CA2582338A1 (en) 2004-09-29 2005-09-08 Host-guest enery-absorbing complex
EP05798023A EP1802961A4 (en) 2004-09-29 2005-09-08 HOST-GUEST ENERGY ABSORPTION COMPLEX
JP2007534618A JP2008514956A (en) 2004-09-29 2005-09-08 Host-guest energy absorbing complex

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61450904P 2004-09-29 2004-09-29
US60/614,509 2004-09-29

Publications (2)

Publication Number Publication Date
WO2006039077A2 WO2006039077A2 (en) 2006-04-13
WO2006039077A3 true WO2006039077A3 (en) 2007-02-08

Family

ID=36142954

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/031972 Ceased WO2006039077A2 (en) 2004-09-29 2005-09-08 Host-guest enery-absorbing complex

Country Status (4)

Country Link
EP (1) EP1802961A4 (en)
JP (1) JP2008514956A (en)
CA (1) CA2582338A1 (en)
WO (1) WO2006039077A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060261267A1 (en) * 2005-05-20 2006-11-23 Agency For Science, Technology And Research Composite MALDI matrix material and methods of using it and kits thereof in MALDI
JP5980517B2 (en) * 2012-02-13 2016-08-31 株式会社島津製作所 Additives for matrix for mass spectrometry
JP5885567B2 (en) * 2012-04-05 2016-03-15 株式会社島津製作所 Additives for matrix for mass spectrometry
US10564076B2 (en) * 2015-06-16 2020-02-18 Agilent Technologies, Inc. Compositions and methods for analytical sample preparation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528320B2 (en) * 1993-05-28 2003-03-04 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015001A2 (en) * 1993-11-12 1995-06-01 Waters Corporation Enhanced resolution maldi tof-ms sample surface
US7276381B2 (en) * 2002-01-25 2007-10-02 Bio-Rad Laboratories, Inc. Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528320B2 (en) * 1993-05-28 2003-03-04 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes

Also Published As

Publication number Publication date
WO2006039077A2 (en) 2006-04-13
JP2008514956A (en) 2008-05-08
EP1802961A2 (en) 2007-07-04
EP1802961A4 (en) 2007-11-14
CA2582338A1 (en) 2006-04-13

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