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WO2000060350A3 - Appareil et procede de detection optique de glucose - Google Patents

Appareil et procede de detection optique de glucose Download PDF

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Publication number
WO2000060350A3
WO2000060350A3 PCT/US2000/008710 US0008710W WO0060350A3 WO 2000060350 A3 WO2000060350 A3 WO 2000060350A3 US 0008710 W US0008710 W US 0008710W WO 0060350 A3 WO0060350 A3 WO 0060350A3
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WO
WIPO (PCT)
Prior art keywords
glucose
solution
optical
magnetic field
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/008710
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English (en)
Other versions
WO2000060350A2 (fr
Inventor
Martin D Fox
Sunghoon Jang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Connecticut
Original Assignee
University of Connecticut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Connecticut filed Critical University of Connecticut
Priority to AU40631/00A priority Critical patent/AU4063100A/en
Publication of WO2000060350A2 publication Critical patent/WO2000060350A2/fr
Publication of WO2000060350A3 publication Critical patent/WO2000060350A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14558—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters by polarisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21—Polarisation-affecting properties

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

La présente invention concerne un appareil et un procédé non-invasif de détection optique de la concentration de glucose dans une solution. Le détecteur optique de glucose est basé sur le fait que les solutions de glucose présentent un effet rotatoire optique magnétique (MORE) de sorte que lorsqu'un champ magnétique est établi dans une solution de glucose il se produit une rotation du vecteur de polarisation de la lumière incidente qui est proportionnelle à la longueur de la trajectoire, de la force de champ magnétique, et de la concentration de glucose dans la solution. Le détecteur optique de glucose comprend un laser qui fait circuler un faisceau de lumière polarisée à travers la solution de glucose (i. e. une humeur aqueuse ou un oeil) tandis qu'une bobine établit un champ magnétique (B) dans la solution. Un tube photomultiplicateur fournit un signal de sortie indiquant la rotation du vecteur de polarisation de la lumière incidente. Le faisceau de lumière est également modulé par un rotateur de Faraday, qui est commandé par un amplificateur synchrone fermant une boucle de réaction. La sortie de l'amplificateur synchrone génère un signal représentatif de la concentration de glucose dans la solution, qui peut être affiché sur un oscilloscope ou fourni à une unité de traitement qui effectue un affichage représentant la concentration de glucose.
PCT/US2000/008710 1999-04-01 2000-03-31 Appareil et procede de detection optique de glucose Ceased WO2000060350A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU40631/00A AU4063100A (en) 1999-04-01 2000-03-31 Optical glucose sensor apparatus and method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28305199A 1999-04-01 1999-04-01
US09/283,051 1999-04-01

Publications (2)

Publication Number Publication Date
WO2000060350A2 WO2000060350A2 (fr) 2000-10-12
WO2000060350A3 true WO2000060350A3 (fr) 2001-08-02

Family

ID=23084275

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/008710 Ceased WO2000060350A2 (fr) 1999-04-01 2000-03-31 Appareil et procede de detection optique de glucose

Country Status (2)

Country Link
AU (1) AU4063100A (fr)
WO (1) WO2000060350A2 (fr)

Cited By (16)

* Cited by examiner, † Cited by third party
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US6958039B2 (en) 2003-05-02 2005-10-25 Oculir, Inc. Method and instruments for non-invasive analyte measurement
US6968222B2 (en) 2003-05-02 2005-11-22 Oculir, Inc. Methods and device for non-invasive analyte measurement
US6975892B2 (en) 2003-10-21 2005-12-13 Oculir, Inc. Methods for non-invasive analyte measurement from the conjunctiva
US8937540B2 (en) 2007-04-14 2015-01-20 Abbott Diabetes Care Inc. Method and apparatus for providing dynamic multi-stage signal amplification in a medical device
US8993331B2 (en) 2009-08-31 2015-03-31 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9000929B2 (en) 2007-05-08 2015-04-07 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US9035767B2 (en) 2007-05-08 2015-05-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US9095290B2 (en) 2007-03-01 2015-08-04 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US9177456B2 (en) 2007-05-08 2015-11-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
US9323898B2 (en) 2005-11-04 2016-04-26 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US9465420B2 (en) 2011-10-31 2016-10-11 Abbott Diabetes Care Inc. Electronic devices having integrated reset systems and methods thereof
US9532737B2 (en) 2011-02-28 2017-01-03 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US9574914B2 (en) 2007-05-08 2017-02-21 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US12482558B2 (en) 2019-12-02 2025-11-25 Abbott Diabetes Care Inc. Medical devices and methods

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US6853854B1 (en) 1998-09-18 2005-02-08 Q Step Technologies, Llc Noninvasive measurement system
US6650915B2 (en) 2001-09-13 2003-11-18 Fovioptics, Inc. Non-invasive measurement of blood analytes using photodynamics
DE10210436A1 (de) * 2002-03-09 2003-10-02 Michael Licht Verfahren und Vorrichtung zur zerstörungsfreien spektroskopischen Bestimmung von Analytkonzentrationen
US6895264B2 (en) 2002-08-26 2005-05-17 Fovioptics Inc. Non-invasive psychophysical measurement of glucose using photodynamics
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
GB2407378B (en) 2003-10-24 2006-09-06 Lein Applied Diagnostics Ltd Ocular property measuring apparatus and method therefor
GB2409033C (en) 2003-12-12 2006-05-24 Lein Applied Diagnostics Ltd Extended focal region measuring apparatus and method
CA2556331A1 (fr) 2004-02-17 2005-09-29 Therasense, Inc. Procede et systeme de communication de donnees dans un systeme de controle et de gestion de glucose en continu
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
CA2690742C (fr) 2007-06-21 2018-05-15 Abbott Diabetes Care Inc. Dispositifs et procedes de gestion de la sante
GB2451443B (en) 2007-07-30 2012-12-26 Lein Applied Diagnostics Ltd Optical measurement apparatus and method therefor
GB2457302B (en) 2008-02-11 2013-04-10 Lein Applied Diagnostics Ltd Measurement apparatus and method therefor
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
WO2010138856A1 (fr) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Systèmes d'antenne de dispositif médical comportant des configurations d'antenne externe
AU2010286917B2 (en) 2009-08-31 2016-03-10 Abbott Diabetes Care Inc. Medical devices and methods
CN101852721B (zh) * 2010-05-18 2012-06-27 南京邮电大学 两种溶质透明混合溶液浓度检测装置
US9636041B2 (en) * 2011-01-28 2017-05-02 Bar Ilan University Method and system for non-invasively monitoring biological or biochemical parameters of individual
WO2012101644A2 (fr) 2011-01-28 2012-08-02 Bar Ilan University Procédé et système de surveillance non invasive de paramètres biologiques et biochimiques d'un individu
EP3677182B1 (fr) 2011-11-07 2022-05-04 Abbott Diabetes Care Inc. Dispositif et procédés de surveillance d'analyte
CN104736042B (zh) 2012-08-01 2017-09-12 巴伊兰大学 用于非侵入地监测个体的生物参数或生化参数的方法和系统
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US8743355B2 (en) 2012-10-16 2014-06-03 K Sciences Gp, Llc Simple sugar concentration sensor and method
US10067054B2 (en) 2012-10-16 2018-09-04 K Sciences Gp, Llc Simple sugar concentration sensor and method
JP6332166B2 (ja) * 2014-03-20 2018-05-30 富士ゼロックス株式会社 光学活性物質の濃度算出システム及びプログラム
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
US11426100B1 (en) 2015-12-08 2022-08-30 Socrates Health Solutions, Inc. Blood glucose trend meter
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
CN115444410B (zh) 2017-01-23 2025-08-15 雅培糖尿病护理公司 用于插入体内分析物传感器的施加器及组件
WO2020095296A1 (fr) 2018-11-11 2020-05-14 Biobeat Technologies Ltd Appareil portable et procédé de surveillance de propriétés médicales
US10813578B1 (en) 2019-12-26 2020-10-27 Biobeat Technologies Ltd. Sensor device for optical measurement of biological properties
JP2023540275A (ja) 2020-08-31 2023-09-22 アボット ダイアベティス ケア インコーポレイテッド 検体センサー挿入のためのシステム、装置、及び方法

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US5685300A (en) * 1994-04-01 1997-11-11 Kuenstner; J. Todd Noninvasive and in-vitro measurement of glucose and cholesterol by nuclear magnetic resonance spectroscopy
US5788632A (en) * 1996-03-19 1998-08-04 Abbott Laboratories Apparatus and process for the non-invasive measurement of optically active compounds

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BROWNE A F ET AL: "MICRODEGREE POLARIMETRIC MEASUREMENT OF GLUCOSE CONCENTRATIONS FOR BIOTECHNOLOGY APLLICATIONS", DURHAM, NEW HAMPSHIRE, MAY 21 - 22, 1997,NEW YORK, IEEE,US, vol. CONF. 23, 21 May 1997 (1997-05-21), pages 9 - 10, XP000738103, ISBN: 0-7803-3849-9 *
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JANG S. AND FOX M.: "Optical sensor using the magnetic optical rotatory effect of glucose", IEEE LEOS NEWSLETTERS, vol. 12, no. 2, April 1998 (1998-04-01), pages 28 - 30, XP002159449 *
JANG SUNGHOON AND FOX MARTIN D: "Double Lock-in Concept for MORE Clucose Detection", WEST HARTFORD, CT, APRIL 8 - 9, 1999,NEW YORK, NY: IEEE,US, 8 April 1999 (1999-04-08), pages 122 - 124, XP002155401, ISBN: 0-7803-5487-7 *

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6968222B2 (en) 2003-05-02 2005-11-22 Oculir, Inc. Methods and device for non-invasive analyte measurement
US6958039B2 (en) 2003-05-02 2005-10-25 Oculir, Inc. Method and instruments for non-invasive analyte measurement
US6975892B2 (en) 2003-10-21 2005-12-13 Oculir, Inc. Methods for non-invasive analyte measurement from the conjunctiva
US9323898B2 (en) 2005-11-04 2016-04-26 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US9095290B2 (en) 2007-03-01 2015-08-04 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US8937540B2 (en) 2007-04-14 2015-01-20 Abbott Diabetes Care Inc. Method and apparatus for providing dynamic multi-stage signal amplification in a medical device
US9402584B2 (en) 2007-04-14 2016-08-02 Abbott Diabetes Care Inc. Method and apparatus for providing dynamic multi-stage signal amplification in a medical device
US9177456B2 (en) 2007-05-08 2015-11-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US9035767B2 (en) 2007-05-08 2015-05-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US9314198B2 (en) 2007-05-08 2016-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US9000929B2 (en) 2007-05-08 2015-04-07 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US9574914B2 (en) 2007-05-08 2017-02-21 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
US8993331B2 (en) 2009-08-31 2015-03-31 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9532737B2 (en) 2011-02-28 2017-01-03 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US9465420B2 (en) 2011-10-31 2016-10-11 Abbott Diabetes Care Inc. Electronic devices having integrated reset systems and methods thereof
US12482558B2 (en) 2019-12-02 2025-11-25 Abbott Diabetes Care Inc. Medical devices and methods

Also Published As

Publication number Publication date
WO2000060350A2 (fr) 2000-10-12
AU4063100A (en) 2000-10-23

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