[go: up one dir, main page]

WO1999061919A3 - Magnetic particle suspending device, apparatus and methods for using same - Google Patents

Magnetic particle suspending device, apparatus and methods for using same Download PDF

Info

Publication number
WO1999061919A3
WO1999061919A3 PCT/US1999/011294 US9911294W WO9961919A3 WO 1999061919 A3 WO1999061919 A3 WO 1999061919A3 US 9911294 W US9911294 W US 9911294W WO 9961919 A3 WO9961919 A3 WO 9961919A3
Authority
WO
WIPO (PCT)
Prior art keywords
container
methods
same
magnetic particle
magnetic particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/011294
Other languages
French (fr)
Other versions
WO1999061919A2 (en
Inventor
Ronald N Diamond
William A Stark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nichols Institute Diagnostics
Original Assignee
Nichols Institute Diagnostics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nichols Institute Diagnostics filed Critical Nichols Institute Diagnostics
Priority to AU40936/99A priority Critical patent/AU4093699A/en
Publication of WO1999061919A2 publication Critical patent/WO1999061919A2/en
Publication of WO1999061919A3 publication Critical patent/WO1999061919A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002Reagent dispensers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/451Magnetic mixers; Mixers with magnetically driven stirrers wherein the mixture is directly exposed to an electromagnetic field without use of a stirrer, e.g. for material comprising ferromagnetic particles or for molten metal
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements
    • G01N2035/00524Mixing by agitating sample carrier
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

There is provided a device, apparatus and methods for suspending magnetic particles retained within a container. In a particular application, magnetic particles which have become settled and even agglutinated at the lowest point, with respect to gravity, in the container, are magnetically pulled from this position, preferably to a sidewall of the container, whereby upon cessation of application of the magnetic force to the container, the particles will no longer be settled and/or agglutinated. In those containers having a fluid contained therein, the magnetic particles can then be easily suspended in the fluid. In a particular embodiment, the container is a vial retained within a cartridge for use in an automated assay apparatus.
PCT/US1999/011294 1998-05-22 1999-05-21 Magnetic particle suspending device, apparatus and methods for using same Ceased WO1999061919A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU40936/99A AU4093699A (en) 1998-05-22 1999-05-21 Magnetic particle suspending device, apparatus and methods for using same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8365098A 1998-05-22 1998-05-22
US09/083,650 1998-05-22

Publications (2)

Publication Number Publication Date
WO1999061919A2 WO1999061919A2 (en) 1999-12-02
WO1999061919A3 true WO1999061919A3 (en) 2000-02-10

Family

ID=22179796

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/011294 Ceased WO1999061919A2 (en) 1998-05-22 1999-05-21 Magnetic particle suspending device, apparatus and methods for using same

Country Status (2)

Country Link
AU (1) AU4093699A (en)
WO (1) WO1999061919A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1499415A4 (en) 2002-04-26 2009-10-28 Abbott Lab Structure and method for handling magnetic particles in biological assays
FR2904114B1 (en) 2006-07-21 2008-10-17 Biocode Hycel France Sa Sa CARTRIDGE FOR REACTIVE PRODUCTS FOR USE IN ANALYTICAL APPARATUSES, CARRIER FOR RECEIVING THIS CARTRIDGE, AND ANALYSIS ASSEMBLY COMPRISING SAID CARTRIDGE AND HOLDER
GB201119521D0 (en) 2011-11-11 2011-12-21 Axis Shield Asa Assay cartridge
KR101355126B1 (en) * 2012-04-24 2014-01-29 주식회사 아이센스 Biochemical assay cartridge
FR3000803B1 (en) * 2013-01-04 2018-05-25 Immunodiagnostic Systems France ANALYSIS ASSEMBLY FOR ANALYSIS APPARATUS
CN109939599A (en) * 2013-04-16 2019-06-28 深圳迈瑞生物医疗电子股份有限公司 Reagent bottle, reagent evenly mixing device and method
GB2532780A (en) * 2014-11-28 2016-06-01 Stratec Biomedical Ag Reagent cartridge
CN109158026B (en) * 2018-09-26 2021-02-05 铜陵市特种设备监督检验中心 Magnetic suspension liquid preparation device and preparation method thereof
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0358948A2 (en) * 1988-08-10 1990-03-21 E.I. Du Pont De Nemours And Company Method for automatically processing magnetic solid phase reagents
EP0567093A2 (en) * 1992-04-23 1993-10-27 Toray Industries, Inc. Automatic analyzing apparatus
WO1993025913A1 (en) * 1992-06-03 1993-12-23 Foss Electric A/S Apparatus and method for performing unit operations involving liquid samples
US5580524A (en) * 1990-09-18 1996-12-03 Anagen Limited Assay or reaction apparatus with agitating device
US5705062A (en) * 1993-09-17 1998-01-06 Hoffmann-La Roche Inc. Analytical device for separating magnetic microparticles from suspensions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0358948A2 (en) * 1988-08-10 1990-03-21 E.I. Du Pont De Nemours And Company Method for automatically processing magnetic solid phase reagents
US5580524A (en) * 1990-09-18 1996-12-03 Anagen Limited Assay or reaction apparatus with agitating device
EP0567093A2 (en) * 1992-04-23 1993-10-27 Toray Industries, Inc. Automatic analyzing apparatus
WO1993025913A1 (en) * 1992-06-03 1993-12-23 Foss Electric A/S Apparatus and method for performing unit operations involving liquid samples
US5705062A (en) * 1993-09-17 1998-01-06 Hoffmann-La Roche Inc. Analytical device for separating magnetic microparticles from suspensions

Also Published As

Publication number Publication date
WO1999061919A2 (en) 1999-12-02
AU4093699A (en) 1999-12-13

Similar Documents

Publication Publication Date Title
RU2138801C1 (en) Particle separation device
JP2702450B2 (en) Method for magnetically separating test components in liquid
CA2255658A1 (en) Method and apparatus for controlling magnetic particles by pipetting machine
WO1999061919A3 (en) Magnetic particle suspending device, apparatus and methods for using same
EP1006359A3 (en) Device and method for separating components of a liquid sample
EP1065001A4 (en) Apparatus for integrating processing of magnetic particles, and method of controlling the same
CA2087037A1 (en) Apparatus and methods for magnetic separation
DE3470806D1 (en) Magnetic means for the removal of magnetic gel particles from a test fluid
CA2563718A1 (en) Apparatus and method for agitating a sample during in vitro testing
US7347338B2 (en) Method for closing and opening of an opening
AU2002222057A1 (en) Methods and devices for transporting and concentrating an analyte present in a sample
WO2001083002A3 (en) Whole blood separator apparatus and method of use
WO2002039949A3 (en) Platelet/leukocyte interaction assay and reagent therefor
EP1281435A3 (en) An improved system and method for stirring suspended solids in a liquid media
EP1088223A4 (en) Methods for performing fibrinogen assays using dry chemical reagents containing ecarin and magnetic particles
WO2003060472A3 (en) An immunochromatographic assay for emp
EP0209490A3 (en) Container for adding antibodies or antigens to a biological liquid
CA2625430A1 (en) Liquid sample collection and transport system
WO2006051548A3 (en) Blood type method system and device
US8431026B2 (en) Apparatus to extract magnetic particles from suspensions
EP2366454A3 (en) Magnetic field and field gradient enhanced centrifugation solid-liquid separations
CA2463307A1 (en) Vial system and method for processing liquid-based specimens
EP0982379A3 (en) Particle surface-modifying method and particle surface-modifying device
GB0111503D0 (en) Microfluidic system for the manipulation and concentration of particles suspended in liquid
WO2001022059A3 (en) Device and method for separation and analysis of small particles

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
NENP Non-entry into the national phase

Ref country code: KR

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase