TWI711377B - Synergistic insecticidal composition - Google Patents

Abstract

A synergistic insecticidal composition comprises component (A), at least one neonicotinoid insecticide, and component (B), at least one avermectin insecticide. There is also provided a method to prevent, control and/or treat insect infestations in plants, plant parts and/or surrounding by applying a combination of component (A), at least one neonicotinoid insecticide, and component (B), at least one avermectin insecticide.

Description

Synergistic insecticidal composition

The present invention relates to a synergistic insecticidal composition comprising two components and to a method of preparing the insecticidal composition. The present invention also relates to a method for preventing, controlling and/or treating insect infestation in the plants, plant parts and/or surrounding environment by applying the synergistic insecticidal composition.

Insect infestation represents a major threat to important economic crops. The yield of plants (for example, vegetables, coffee, citrus, fiber plants, Cucurbitaceae, fruits, and legumes) can be adversely affected by insect infestation.

Chemical control is an important way to prevent and control pests in agriculture. However, current medicaments show unsatisfactory effects on certain types of harmful organisms. In addition, due to the long-term use of pesticides, many harmful organisms have developed resistance to these commonly used pesticides. Therefore, there is an urgent need to develop new methods and pesticides for controlling these harmful organisms. In addition, the environmental and economic requirements for modern insecticides continue to increase, such as with regard to action spectrum, toxicity, selectivity, application rate, residue formation, and favorable preparation procedures. Since there may be problems such as resistance to known active compounds, continuous research and development are required, at least in some aspects, relative to their known counterparts. New pesticides with advantages.

Neonicotine insecticides are well-known insecticides with a broad spectrum of insect control. They have been developed as insecticides with reduced toxicity compared to previously used organophosphorus and carbamates that provide similar broad-spectrum control to numerous crop-damaging pests. Neonicotine is now an insecticide widely used in the world and registered in more than 120 countries. Examples of neonicotine include imidacloprid, thiamethoxam, clothianidin, acetamiprid, thiacloprid, dinotefuran, and dinotefuran. (sulfoxaflor) and nitenpyram (nitenpyram).

Experience gained from using single active pure formulation insecticides around the world shows that the risk of developing subpopulations of resistant insects is high. It has been reported that more and more insects have developed resistance in field crops, fruits, vegetables, etc. throughout the world. Mixing new nicotine insecticides with other insecticides can reduce resistance selection pressure among target pests.

Ivermectin insecticides are isolated from the fermentation of Streptomyces avermitilis (Streptomyces avermitilis) (naturally occurring soil actinomycetes). Ivermectin acts by stimulating the release of gamma-aminobutyric acid (an inhibitory neurotransmitter), thereby ultimately activating chloride channels. Examples of ivermectin include abamectin and emamectin benzoate.

Enhancing insecticides and insecticidal compositions have been achieved to improve the control of insect pests and be applied to target crops in single or mixed pesticide applications. In areas where there is only a high incidence of insects, use tape, spot, and soil applications with caution to avoid direct contact with natural enemies, and selective and non-persistent testing The use of agents increases environmental safety and reduces the incidence of insect resistance. In addition, the use of rotation of insect control agents with different modes of action contributes to good pest management.

It is desirable that the insecticidal composition has a high synergistic effect on existing insecticides with little or no cross-resistance, and has low environmental impact. It would be advantageous to provide a composition that is effective in insect attack, can be prepared as a physically compatible formulation that is stable during storage, can be safely packaged, and can be prepared as a ready-to-use formulation.

Unexpectedly, it has now been found that a composition comprising (A) at least one new nicotine insecticide and (B) at least one ivermectin insecticide exhibits synergistic activity against a series of insect pests and is a series of crops and plants. Provides significantly improved protection.

US 6,444,690 relates to insecticidal compositions containing chloronicotine insecticides and insecticide synergists. However, this patent does not disclose any specific synergistic combination of neonicotine insecticide and ivermectin insecticide, but does only disclose the test on cabbage leaves.

According to the present invention, in the first aspect, there is provided an insecticidal composition comprising at least one novel nicotine insecticide as component (A) and at least one ivermectin insecticide as component (B).

In another aspect, the present invention provides for control by applying (A) at least a new nicotine insecticide and (B) at least one ivermectin insecticide to plants, plant parts and/or their surrounding environment Such plants, plant parts and/or Methods of infestation by insects in the surrounding environment.

In still another aspect, the present invention provides a combination of (A) at least a new nicotine insecticide and (B) at least one ivermectin insecticide for controlling insects in plants, plant parts and/or their surrounding environment Use in infestation.

The present invention also provides a method for preparing a synergistic insecticidal composition, the method comprising as component (A) at least one new nicotine insecticide and at least one ivermectin as component (B) Insect agents are combined.

The present invention also provides plants or plant parts treated with (A) at least a new nicotine insecticide and (B) at least one ivermectin insecticide, the plant or plant part being treated before being infected by insects, And/or treatment to combat existing insect infestation.

"Plant" as used herein refers to all plants and plant groups, such as desired and undesired wild plants or crop plants.

"Plant parts" as used herein refers to all parts and organs of plants, such as buds, leaves, needles, stems, stems, fruiting bodies, fruits, seeds, roots, tubers, and rhizomes. It also includes harvested material and vegetative and reproductive propagation material, such as cuttings, tubers, meristem tissue, rhizomes, lateral branches, seeds, single and multiple plant cells, and any other plant tissues.

The expression "surrounding" or "surroundings" refers to the place or place where the plant is growing, the place where the plant propagation material of the plant has been sown, or the place where the plant propagation material of the plant is to be sown.

"At least one" means multiple of 1, 2, 3, 4, 5, 6, 7, 8, 9 or more of the corresponding compounds, preferably 1, 2, or 3 types.

When used in conjunction with a numerical quantity, "about" includes the numerical quantity and the achievement of the numerical quantity The deviation of ±5% of the value is lower or higher than some numerical value of the value.

It has now surprisingly been found that when a combination of component (A) at least one new nicotine insecticide and component (B) at least one ivermectin insecticide is applied to plants, plant parts and/or their surrounding environment, Obtain a particularly effective treatment and/or protection against insect infestation. The combination of (A) and (B) exhibits synergistic effects and can effectively protect and treat a wide range of plants and crops, especially potatoes, coffee, citrus, melon, red pepper, soybeans, potatoes, cotton, pistachios. In these crops, excellent performance in preventing and treating insect infestation can be observed.

It was found that the synergistic combination of (A) at least new nicotine insecticide and (B) at least one ivermectin insecticide has high activity against a wide range of pests, including spider mite, psyllid, leaf miner Insects (leafminer), aphids, moths, whiteflies, stink bugs, thrips, asian citrus psyllid, liriomyza leafminer, gnats, broad mite), citrus bud mite, citrus root weevil, citrus rust mite, citrus thrip, colorado potato, beetle, Leafhoppers (flea beetle leafhopper), mealy bugs, scales, tomato pinworms (tomato pinworm), tomato psyllid and tomato psyllid (russet mite).

The technology of the present invention also exhibits reduced application costs, increased crop yields and reduced environmental risks. The present invention also delays the advantages of pest resistant strains, has a broader spectrum of activity than comparable known treatments, and reduces the risk of target pests developing drug resistance.

The present invention can be applied to treat and/or protect a wide range of plant materials at all developmental stages. In an advantageous embodiment, the combination of (A) at least a neonicotine insecticide and (B) at least one ivermectin insecticide is suitable for reproductive parts of plants and especially seeds. For example, the seeds may be coated with a synergistic composition and/or contain a synergistic composition comprising component (A) at least one new nicotine insecticide and component (B) at least one ivermectin Insecticide.

In the method and use of the present invention, components (A) and (B) can be applied in any desired order, any combination, consecutively or simultaneously. In a preferred embodiment, (A) at least neonicotine insecticide and (B) at least one ivermectin insecticide are applied in the form of the composition of the present invention. However, this is not necessary and components (A) and (B) can be used separately and combined in, for example, a place to be treated.

In the composition of the present invention, the at least one new nicotine insecticide of component (A) may be present in any suitable amount, and is usually present in the following amount: at least 1% by weight of the composition, more preferably At least 2% by weight, still more preferably at least 5% by weight, and still more preferably at least 10% by weight. Component (A) can be present in the following amounts: up to 99% by weight of the composition, more preferably up to 95% by weight, still more preferably up to 85% by weight, still more preferably Is up to 80% by weight. Component (A) may be present in the composition in the following amounts: from about 1% to about 75% by weight of the composition, preferably from about 20% to about 60% by weight of the composition, more It is preferably from about 25% to about 40% by weight of the composition.

The one or more new nicotine insecticides of component (A) can be any Insect active new nicotine compound. Such compounds are known in the art and are commercially available. Component (A) is preferably one or more neonicotinoids selected from the following: idamide, acesulfame, knitidine, acesulfame, aceguope, dartnan, sulfonamide, Nitenpyram and mixtures thereof. Idalamide is a particularly preferred neonicotine for use in the present invention.

In the composition of the present invention, the component (B) at least one ivermectin insecticide may be present in the composition in any suitable amount, and is usually present in the following amount: at least 0.2% by weight of the composition, It is preferably at least 0.5% by weight, more preferably at least 0.75% by weight, and still more preferably from 1% by weight. Component (B) may be present in the following amounts: up to 90% by weight of the composition, more preferably up to 75% by weight, still more preferably up to 65% by weight, still more preferably Is up to 50% by weight. Component (B) may be present in the composition in the following amounts: from about 1% to about 50% by weight of the composition, preferably from about 1% to about 20% by weight of the composition, more It is preferably from about 1% to about 10% by weight of the composition, and most preferably from about 1% to about 5% by weight of the composition.

The one or more ivermectin insecticides of component (B) may be any insecticidal active ivermectin compound. Such compounds are known in the art and are commercially available. Component (B) is preferably one or more ivermectins selected from the following: Abatin, Inmectin and mixtures thereof.

Components (A) and (B) may be present in the composition or applied in any amount relative to each other to provide a synergistic effect of the combination. Specifically, the weight ratio of components (A) and (B) utilized in the present invention can be from about 25:1 to about 1:25, preferably from about 20:1 to about 1:20, More preferably from about 15:1 To about 1:15, still more preferably about 12:1 to about 1:12.

It is generally preferred that component (A) is present in excess of component (B) in terms of the weight of the active ingredient. Specifically, the weight ratio of component (A) and component (B) used in the present invention is preferably at least 2:1, more preferably at least 3:1, and still more preferably at least 5. :1, still more preferably at least 7:1, especially at least 9:1. The weight ratio of component (A) to component (B) is preferably as high as 20:1, more preferably as high as 15:1, and still more preferably as high as 12:1. The weight ratio of component (A) and component (B) is preferably from 2:1 to 20:1, more preferably from 3:1 to 18:1, still more preferably from 5:1 To 15:1. In some preferred embodiments, the weight ratio of component (A) to (B) is from 6:1 to 14:1, preferably from 8:1 to 13:1, more preferably from 9:1 to 12:1, with a weight ratio of about 11:1 being particularly preferred for many treatments.

In the composition of the present invention, components (A) and (B) may be present together in any suitable amount, and are usually present in the following total amount: from about 2% to about 95% by weight of the composition, which is more Preferably, it is from about 20% to about 70% by weight of the composition, more preferably from about 25% to about 45% by weight of the composition.

The composition of the present invention may contain one or more adjuvants, as known in the art. The adjuvant used in the composition will depend on the type of formulation and/or the way the end user administers the formulation. The formulations included in the composition of the present invention are as follows. Suitable adjuvants that can be included in the composition according to the present invention are all customary formulation adjuvants or components, such as extenders, carriers, solvents, surfactants, stabilizers, defoamers, antifreezes, Preservatives, antioxidants, colorants, thickeners, solid binders and inert fillers. Such adjuvants are known in the art and are commercially available. Their use in the formulation of the composition of the embodiment of the invention It is obvious to those who are familiar with the technology.

The insecticidal composition may further comprise one or more inert fillers. Such inert fillers are known in the art and are commercially available. Suitable fillers in solid form include, for example, natural ground minerals (such as kaolin, alumina, talc, chalk, quartz, attapulgite, montmorillonite and diatomaceous earth) or synthetic above-ground minerals (such as highly dispersed Silicic acid, alumina, silicate and calcium phosphate and calcium hydrogen phosphate). Suitable inert fillers for granules include, for example, crushed and classified natural minerals (such as calcite, marble, pumice, sepiolite, and dolomite) or synthetic particles of inorganic and organic ground materials and particles of organic materials (such as sawdust, coconut shell, Corn cob and tobacco stem).

The insecticidal composition optionally includes one or more nonionic, cationic and/or anionic surfactants and a mixture of surfactants with good emulsifying, dispersing and wetting properties, depending on the type to be formulated The nature of the active compound. Suitable surfactants are known in the art and are commercially available. Suitable anionic surfactants can be both so-called water-soluble soaps and water-soluble synthetic surface-active compounds. Usable soaps are alkali metal salts, alkaline earth metal salts or substituted or unsubstituted ammonium salts of higher fatty acids (C10 to C22), such as sodium or potassium salts of oleic acid or stearic acid or natural fatty acid mixtures.

The surfactant can be an ionic or non-ionic emulsifier, dispersant or wetting agent. Examples that can be used are the salt of polyacrylic acid, the salt of lignosulfonic acid, the salt of benzenesulfonic acid or naphthalenesulfonic acid, the condensation polymer of ethylene oxide and fatty alcohol or fatty acid or fatty amine, substituted phenol (especially It is alkylphenol), sulfosuccinate salt, taurine derivative (especially alkyltaurate) or polyethoxylated phenol or alcohol phosphate.

When the active compound and/or inert carrier and/or adjuvant/adjuvant are not soluble in water and the final application carrier of the composition is water, it is usually necessary to have at least one surfactant.

The insecticidal composition optionally further contains one or more polymerization stabilizers. Suitable polymerization stabilizers that can be used in the present invention include, but are not limited to, polypropylene, polyisobutylene, polyisoprene, copolymers of monoolefins and dienes, polyacrylates, polystyrene, polyvinyl acetate, Polyurethane or polyamide. Suitable stabilizers are known in the art and are commercially available.

It is believed that the above-mentioned surfactants and polymerization stabilizers generally impart stability to the composition, thereby allowing the formulation, storage, transportation, and application of the composition.

Suitable defoamers include all substances that can generally be used for this purpose in agrochemical compositions. Suitable defoamers are known in the art and are commercially available. A particularly preferred defoamer is a mixture of polydimethylsiloxane and perfluoroalkylphosphonic acid, such as the silicone defoamer available from GE or Compton.

Suitable organic solvents are selected from all customary organic solvents which fully dissolve the active compound used. Likewise, suitable organic solvents for the active components (A) and (B) are known in the art. The following may be preferred: N-methylpyrrolidone, N-octylpyrrolidone, cyclohexyl-1-pyrrolidone; or SOLVESSOTM200, paraffinic hydrocarbons, isoparaffinic hydrocarbons, cycloparaffinic hydrocarbons and aromatics A mixture of group hydrocarbons. Suitable solvents are commercially available.

Suitable preservatives include all substances that can be commonly used for this purpose in this type of agrochemical composition and are also well known in the art. Suitable examples that may be mentioned include PREVENTOL® (from Bayer (Bayer AG)) and PROXEL® (from Bayer).

Suitable antioxidant systems can be all substances commonly used for this purpose in agrochemical compositions, as known in the art. Preferably it is butylated hydroxytoluene.

Suitable thickeners include all substances commonly used for this purpose in agrochemical compositions, such as xanthan gum, polyvinyl alcohol (PVOH), cellulose and its derivatives, clay hydrated silicate, silicic acid Magnesium aluminum or mixtures thereof. Likewise, such thickeners are known in the art and are commercially available.

The insecticidal composition may further comprise one or more solid adhesives. Such adhesives are known in the art and are commercially available. They include organic binders (including tackifiers) (such as cellulose or substituted cellulose), natural and synthetic polymers in powder, granular or lattice form, and inorganic binders (such as gypsum, silica or cement).

In addition, depending on the formulation, the composition according to the present invention may also contain water.

In some embodiments, the method, use or composition according to the present invention utilizes a combination of the following components: (A) Idamide and (B) Abatin; or (A) Idamide and (B) Inventine .

According to a preferred embodiment, the method, use or insecticidal composition according to the present invention utilizes idamide as component (A) and abatine as component (B).

Each composition, method or use of the present invention can be used in the agricultural sector and related fields to control a wide range of insects, such as but not limited to: ‧ aphids on tomatoes; tea mites; beetles; leafhoppers; Liriomyza spp. Leafminer; spider mites (Tetranychus urticae), spider mites Ivan (Tetranychus evansi)); Thrips (Thrips palmi); Tomato pinworms; Tomato psyllids; Tomato spiny gall mite; Whitefly; and Moths (Tuta absoluta); ‧ Citrus Aphids on the genus (Toxoptera citricida); Asian citrus psyllids (Diaphorina citri); Gnats; Tea mites; Orange bud mites; Citrus leaf miners (Citrus) leafminer) (Phyllocnistis citrella); Citrus root weevil (larval complex); Citrus rust mite; Citrus thrips; Leafhopper/Sharpshooter; Leafminer (Leafminer); Mealbug; Scale insects; Two-spotted spider mite (Tetranychus urticae); whiteflies; thrips; and spider mites; ‧ aphids on pistachio (Black pecan aphid) ); European red mite (Panonychus ulmi); Tetranychus urticae; Whitefly; Pistachio psylla (Agonoscena pistaciae); and Tetranychus; ‧Aphids on cotton (cotton aphid); and Thrips (Western flower thrips); ‧Leaf miner on coffee (Coffee leaf miner); ‧Whitefly on melon (Bemisia tabaci breeding ( Bemisia tabaci raça B); and leaf miner (Liriomyza huidobrensis); ‧ aphids on potato (green peach aphid); and leaf miner (Liriomyza huidobrensis); ‧ red pepper Thrips (Thrips palm); ‧Stink bugs (Euschistus heros) on soybeans; Tetranychus urticae (Tetranychus urticae); Stink bugs (Piezodorus); And mites (Mononychellus planki); and ‧ spider mites on roses (Tetranychus urticae, Tetranychus Ivani).

The method, use and composition of the present invention have shown surprisingly high effectiveness in controlling insect infestation caused by: ‧Tetranychus urticae on tomato (Tetranychus urticae, Tetranychus Ivanii); Thrips ( Palm thrips); and moths (Lyrimus tomato); ‧Aphids on the genus Citrus (Aphid citrus); Leaf miners (Citrus leaf miners); Tetranychus urticae (Tetranychus urticae); and Asia Citrus psyllid (Citrus psyllid); ‧European red mite (Palonychus elm) on pistachios; and Psyllid psyllus (Psyllus psyllus); ‧Aphids on cotton (cotton aphid) ; And thrips (Western flower thrips); ‧ leaf miner on coffee (coffee leaf miner); ‧ whitefly on melon (tobacco whitefly type B); and leaf miner (liriomyza huidobrensis); ‧Aphids on potatoes (Myzus persicae); and leaf miners (Liriomyza huidobrensis); ‧Thrips on red peppers (Thrips palm); ‧Stink bugs on soybeans (Hero American bug); Tetranychus urticae ( Tetranychus urticae); stink bugs (Lepidoptera spp.); and mites (Monoconychus Planckii); and Tetranychus urticae on roses (Tetranychus urticae, Tetranychus Ivani).

The compositions, methods and uses according to the embodiments of the present invention are suitable for treating a wide range of plants and crops, including: cereals (wheat, barley, rye, oats, corn, rice, sorghum, triticale and related crops); fruits , Such as pears, stone fruits and soft fruits, such as apples, grapes, pears, plums, peaches, almonds, pistachios, cherries and berries (such as strawberries, raspberries and blackberries), bell peppers, red peppers; legumes Plants (beans, lentils, peas, soybeans); oil plants (canola, mustard, sunflower); Cucurbitaceae (summer squash, cucumber, melon); fiber plants (cotton, flax, hemp, jute); citrus, such as citrus , Citrus citrus, citrus hybrids (including chironja, tangerine, citrus), grapefruit, kumquat, lemon, lime, mandarin (tangerine), bitter orange, sweet Orange, pomelo and satsuma mandarin; vegetables (spinach, lettuce, asparagus, kale, carrot, onion, tomato, potato, pepper); coffee; and ornamental plants (flowers such as roses, shrubs, broad-leaved trees, and evergreen plants such as conifer).

In some embodiments, the present invention is applied to the treatment of fruits, cucurbitaceae, citrus fruits, vegetables, coffee, fibers, legumes, and ornamental plants. In some embodiments, the present invention is applied to the treatment of potato, coffee, citrus, melon, red pepper, soybean, tomato, cotton, pistachio and flower.

The combination of component (A) at least one new nicotine insecticide and component (B) at least one ivermectin insecticide is particularly effective in controlling and preventing the infestation of: ‧Tetranychus on tomato ( Tetranychus urticae, Tetranychus Ivani); Thrips (Thrips palm); Moths (Liriomyza tomato); Aphids on the genus Citrus (Aphid citrus); Leaf miners (Citrus leaf miners) ); Tetranychus urticae (Tetranychus urticae); and Asian citrus psyllid (Citrus psyllid); European red mites on pistachio (Palonychus elm); and pistachio psyllids (Pistachio pistachio) Psylla carina); ‧ aphids on cotton (cotton aphid); and thrips (western flower thrips); ‧ leaf miners on coffee (coffee leaf miners); ‧Whitefly on melon (Whitefly B); and leaf miner (Liriomyza huidobrensis); ‧Aphids on potato (Myzus persicae); and leaf miner (Liriomyza huidobrensis); ‧On red pepper的Thrips (Thrips palm); ‧Stink bugs on soybeans (Hero American bug); Tetranychus urticae (Tetranychus urticae); Stink bugs (Tripodidae); and mites (Monoconychus Planckii); and Spider mites on roses (Tetranychus urticae, Tetranychus Ivanii).

The present invention can be applied in the treatment of plants, plant parts and/or their surrounding environment.

The present invention is particularly effective in controlling the infestation of: ‧Tetranychus mites (Tetranychus urticae and Tetranychus Ivani) on tomatoes; and Thrips (Thrips palm); and Moths (Liriomyza tomato) ‧Aphids on the genus Citrus (Citrus aphid); Citrus leaf miner (Citrus leaf miner); Tetranychus urticae (Tetranychus urticae); and Asian citrus psyllid (Citrus psyllid); ‧Pistachio pistachio European red mite (Palonychus elm); and pistachio psyllid (Psylla lunata); ‧aphids on cotton (cotton aphid); and thrips (Western flower thrips); ‧coffee Leaf miner (Coffee leaf miner); ‧Whitefly on melon (Whitefly type B); and Leafminer (Liriomyza huidobrensis); ‧Aphids on potato (Myzus persicae); and Leaf miner Insects (Liriomyza huidobrensis); ‧Thrips on red pepper (Thrips palm); ‧Stink bugs on soybeans (Hero American bug); Tetranychus urticae (Tetranychus urticae); Stink bugs (Lepidoptera spp.); And mites (Monoconychus Planckii); and ‧Tetranychus mites on roses (Tetranychus urticae, Tetranychus Ivani).

As mentioned above, the synergistic insecticidal composition comprising component (A) at least one new nicotine insecticide and component (B) at least one ivermectin insecticide can be used to improve The treatment is applied to the plant, its plant parts and/or its surrounding environment, wherein the weight of the applied components (A) and (B) is preferably about 11:1.

The present invention is particularly effective in controlling the following items: ‧Tetranychus mites (Tetranychus urticae and Tetranychus Ivanii) on tomatoes; Thrips (Thrips palm); Moths (Liriomyza tomato); ‧Citrus Aphid (Citrus aphid); Citrus leaf miner (Citrus leaf miner); Tetranychus urticae (Tetranychus urticae); and Asian citrus psyllid (Citrus psyllid); ‧European red on pistachio Mites (Palonychus elm); and pistachio psyllids (Psylla lunata); aphids on cotton (cotton aphid); and thrips (western flower thrips); ‧leaf miners on coffee Insects (Coffee leaf miner); ‧Whitefly on melon (Whitefly type B); and Leafminer (Liriomyza huidobrensis); ‧Aphids on potato (Myzus persicae); and Leafminer (South American spot Liriomyza); ‧Thrips on red peppers (Thrips palm); ‧Stinkbugs on soybeans (Hero American stinkbug); Tetranychus urticae (Tetranychus urticae); Stink bugs (Lepidoptera); and mites (Pulan) Gram monoclawed mites); and ‧ spider mites on roses (Tetranychus urticae, Tetranychus Ivani).

As mentioned above, in a preferred embodiment, the present invention utilizes idamide as component (A) and abatine as component (B). Component (A) and (B) The particularly effective weight ratio in the composition is about 11:1.

This type of combination of Idamide and Abatin is particularly effective in controlling the following: ‧Tetranychus urticae (Tetranychus urticae, Tetranychus ivani) on tomatoes; Thrips (Thrips palm); and Moths ( Liriomyza tomato); ‧Aphids on Citrus (Citrus aphid); Citrus leaf miner (Citrus leaf miner); Two-spotted spider mite (Tetranychus urticae); and Asian citrus psyllid (Citrus psyllid) ‧European red mite on pistachio (Panonychus elm); and pistachio psyllid (Psyllus psyllus); ‧ aphids on cotton (cotton aphid); and thrips (western flower thistle) Horse); ‧Leaf miner on coffee (Coffee leaf miner); ‧Whitefly on melon (Whitefly type B); and Leafminer (Liriomyza huidobrensis); ‧Aphids on potato (Myzus persicae) ); and leaf miner (Liriomyza huidobrensis); ‧Thrips on red pepper (Thrips palm); ‧Stinkbug on soybeans (Hero American bug); Tetranychus urticae (Tetranychus urticae); Stinkbug ( Spp.); and mites (Monoconychus Planckii); and ‧ spider mites (Tetranychus urticae, Tetranychus Ivani) on roses, when the components (A) idamide and (B) ) When a synergistic combination of abatin (preferably in the form of a composition) is applied to plants, their plant parts and/or the surrounding environment, the weight of component (A) is approximately based on the weight of the composition. 30%; and the weight of component (B) is about 2.8% by weight of the composition.

Use at least one new nicotine insecticide containing as component (A) and A composition of at least one ivermectin insecticide as component (B) is used to control insect infestation in plants and plant parts. The composition containing the components (A) Idamide and (B) Abatin can be used to control the following: ‧Tetranychus urticae (Tetranychus urticae, Tetranychus ivani) on tomatoes; Thrips (palm Thrips); and moths (Lycopersicon esculenta); ‧Aphids on Citrus (Citrus aphid); Citrus leaf miner (Citrus leaf miner); Tetranychus urticae (Tetranychus urticae); and Asian citrus Psyllids (Asian citrus psylla) (Citrus psyllids); ‧European red mites (Palonychus elm) on pistachios; and Psyllids (Psyllus psyllus); ‧Aphids on cotton (Cotton aphid); and Thrips (Western Flower Thrips); ‧Leaf miner on coffee (Coffee leaf miner); ‧Whitefly on melon (Whitefly type B); and Leafminer (South American spot Liriomyza); ‧Aphids on potato (Myzus persicae); and Leafminer (Liriomyza huidobrensis); ‧Thrips on red peppers (Thrips palm); ‧Stinkbugs on soybeans (Hero american bug); 2 Tetranychus urticae (Tetranychus urticae); Stinkbug (Tetranychus spp); and mites (Monoconychus Planckii); and Tetranychus urticae on roses (Tetranychus urticae, Tetranychus Ivanii).

Each composition can be applied to the leaves or fruits of the plant or the environment around the plant.

More specifically, a composition comprising at least one new nicotine insecticide as component (A) and at least one ivermectin insecticide as component (B) is used to control insect infestation in plants and plant parts dye. Contains component (A) The combination of damine and (B) abatin can be used to control: moths on tomatoes (liriomyza lycopersicum); European red mites (panonychus elm) on pistachios and pistachio psyllids (Ah Psyllid psyllids); thrips on cotton (Western flower thrips); leaf miners on coffee (coffee leaf miners); leaf miners on melon (liriomyza huidobrensis); stink bugs on soybeans (Hero American bug), two-spotted spider mites (two-spotted spider mite), stinkbugs (Bonus genus), and mites (Planck-monoclawed mites); and spider mites on roses (two-spotted spider mites, Ivans spider mites) ).

The composition of the present invention may contain other pesticides (such as fungicides), other insecticides and nematicides, growth factors and fertilizers or be mixed with them. Similarly, in the methods and uses of the present invention, components (A) and (B) can be used together with other pesticides (such as fungicides), other insecticides and nematicides, growth factors and fertilizers.

The application (usage) amount of the components (A) and (B) of the present invention can vary, for example, according to the type of use, crop type, specific active compound in the combination, and plant type, but the active compound in the combination is made as desired. It is applied in an effective amount for effects (such as insect or pest control). The application amount of the component for a given set of conditions can be easily determined by experimentation.

Components (A) and (B) and any other pesticides can be applied and used in pure form as solid active compounds, for example at a specific particle size, or preferably together with at least one adjuvant or adjuvant component And use, as are customary auxiliaries or adjuvant components in formulation technology, such as extenders, for example solvents or solid carriers or surface active compounds (surfactants), as described in more detail above. Generally, components (A) and (B) are in the form of a formulation composition together with one or more of the above-mentioned customary formulation assistants.

Examples of the types of formulations used in the premix composition are: solution (SL), emulsion (EC), water-based emulsion (EW), microemulsion (ME), oil-based suspension (OD), seed treatment suspension (FS) ), water-dispersible granules (WG), water-soluble granules (SG), water-dispersible powder (WP), water-soluble powder (SP), granules (GR), capsule granules (CG), fine granules (FG), macrogranules (GG), aqueous suspension emulsions (SE), microcapsule suspensions (CS), microgranules (MG) or preferably aqueous suspensions (SC).

Using pure (ie undiluted) or diluted with a suitable solvent (especially water) such preparations can be sprayed, poured or soaked to treat plants, plant parts and/or the surrounding environment and protect them from Insect influence. Generally, the formulation can be diluted with water at a ratio of 10 to 1000 mL or 10 to 800 mL of the formulation in 100 L of water.

In some embodiments, the composition is an aqueous suspension. For aqueous suspension formulations, the composition can be diluted with water at a ratio of 10 to 600 mL of the composition in 100 L of water. For an aqueous suspension formulation applied to tomatoes, the composition can be diluted with water at a concentration of 10 to 150 mL in 100 L of water, more preferably 10 mL to 90 mL in 100 L of water (water 1000 L/ha). For aqueous suspension formulations applied to citrus, the composition can be used in 100 L of water with a concentration of 10 to 150 mL, more preferably 10 mL to 50 mL of 100 L of water (water 2000L to 5000L/ha). dilution. For an aqueous suspension formulation applied to pistachios, the composition can be diluted with water at a concentration of 10 mL to 150 mL in 100 L of water, more preferably 10 mL to 50 mL in 100 L of water (water 1000 L/ha). .

For aqueous suspension formulations applied to potatoes and melons, the composition can be The composition is 10 to 800 mL/ha, preferably from 100 to 600 mL/ha, and most preferably 300 mL/ha is diluted with water.

For water suspension formulations applied to coffee and red pepper, the composition can be used at a concentration of 10 to 800 mL/ha, preferably from 100 to 400 mL/ha, and most preferably 250 to 300 mL/ha. dilution.

For aqueous suspension formulations applied to soybeans, the composition can be diluted with water at a concentration of 10 to 800 mL of composition/ha, preferably from 100 to 600 mL/ha, and most preferably 300 to 400 mL/ha.

For water suspension formulations applied to flowers (such as roses), the composition can be made at a concentration of 10 to 800 mL/ha, preferably from 200 to 700 mL/ha, and most preferably 450 to 650 mL/ha. Dilute with water.

Components (A) and (B) can be applied to plants, plant parts and their surroundings at a ratio of from about 1 g to about 500 g total active ingredients per hectare, preferably from about 20 g to about 400 g total active ingredients per hectare .

Components (A) and (B) can be applied using any method known in the art. Such methods include coating, spraying, dipping, soaking, injection and irrigation.

The active ingredients (A) and (B) can be applied simultaneously or continuously at short intervals (for example, on the same day) to plants, plant parts and/or their surrounding environment that it is desired to control. Components (A) and (B) can be applied to the plant, one or more parts thereof (such as leaves or seeds) or the surrounding environment in any order. Each component can be applied only once or multiple times. Preferably, each of the components (A) and (B) is applied multiple times, specifically from 2 to 5 times, more preferably 2 to 3 times.

The active ingredients (A) and (B) can be administered in any suitable form, as described above. Typically, the active ingredient is administered as a formulation, i.e. containing one or more The active ingredient is combined with additional carriers, surfactants, or other adjuvant-facilitating compositions commonly used in formulation techniques.

In the case of simultaneous application of components (A) and (B) in the present invention, they may be applied as a composition containing components (A) and (B), in this case, components (A) and (B) can be obtained from separate formulation sources and mixed together (called tank mixes, ready-to-use applications, spray liquids or slurries), as appropriate with other pesticides; or components (A) and (B) ) Can be obtained as a single source of formulation mixture (referred to as premix, concentrate, formulated compound (or product)), and mixed with other pesticides as appropriate.

The compositions, methods and uses according to the invention are characterized in that they are particularly well tolerated by plants and are environmentally friendly.

The embodiments of the present invention will be further described by the following examples, which are given to illustrate the method of the present invention rather than to limit the present invention.

Percentages are expressed as percentages by weight, unless otherwise stated.

In the following formulation examples, Examples 1 to 3 are comparative examples and do not provide an embodiment of the present invention.

Example 1- Edamide (50%)-WG

Prepare a water dispersible granule (WG) formulation with the following composition:

Example 2-Abatin (10%)-EC

Prepare an emulsion (EC) with the following composition:

Example 3-Inmectin (10%)-EC

Prepare an emulsion (EC) with the following composition:

Example 4-Idamide (30%) + Abatin (2.8%)-SC

將精細研磨的益達胺和阿巴汀與助劑緊密地混合，給出水懸劑，從該水懸劑可以藉由用水稀釋獲得具有任何希望稀釋度的懸浮液。 Prepare an aqueous suspension (SC) with the following composition:

The finely ground idadamide and abatine are mixed closely with the adjuvant to give an aqueous suspension from which a suspension with any desired dilution can be obtained by dilution with water.

Example 5-Idamide (30%) + Inmectin (2.8%)-SC

Prepare an aqueous suspension (SC) with the following composition:

The finely ground idazamide and inpentine are intimately mixed with the adjuvant to give an aqueous suspension from which a suspension with any desired dilution can be obtained by diluting with water.

Example 6-Idamide (20%) + Abatin (5%)-SC

Prepare an aqueous suspension (SC) with the following composition:

The finely ground Idamide and Abatin are mixed closely with the adjuvant to give an aqueous suspension from which a suspension with any desired dilution can be obtained by dilution with water.

Example 7-Idamide (40%) + Inmectin (1.5%)-SC

Prepare an aqueous suspension (SC) with the following composition:

The finely ground idazamide and inpentine are intimately mixed with the adjuvant to give an aqueous suspension from which a suspension with any desired dilution can be obtained by diluting with water.

Example 8-Idamide (50%) + Abatin (1%)-SC

Prepare an aqueous suspension (SC) with the following composition:

The finely ground Idamide and Abatin are mixed closely with the adjuvant to give an aqueous suspension from which a suspension of any desired dilution can be obtained by dilution with water.

Example 9-Idamide (30%) + Abatin (2.8%)-EC

Prepare an emulsion (EC) with the following composition:

Example 10-Idamide (30%) + Abatin (2.8%)-WP

Prepare water dispersible powder (WP) with the following composition:

Biological examples

When the activity of the composition containing the two active compounds is greater than the sum of the activities of the two active compounds administered alone, the combination of the two active compounds has a synergistic effect. The expected activity of a given combination of two active compounds can be calculated by the so-called "Colby equation" (see SR Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations" of Herbicide Combinations)", Weeds 1967, 15, 20-22): Thus: A = when the active compound A is used at an application rate of mg/ha, the percentage of activity of compound A; B = when it is measured in ng When using active compound B at an application rate of /ha, the activity percentage of compound B; E=the estimated activity percentage when using compound A and B together at an application rate of mg/ha and ng/ha; then: E=A+ B-(A×B/100).

If the actual activity observed for the combination of compounds A and B is greater than the calculated activity, then the activity of the combination is superadditive. In other words, there is a synergy.

Field trial 1-Tomato-Tetranychus (Tetranychus urticae)

The spider mites (Tetranychus urticae) are reared in the laboratory. Count the number of mites, collect the mites and place them on healthy young tomato plants.

Samples of the respective formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining mite population was checked and the number of remaining mites was counted. The results are listed in Table A.

The results in Table A show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 2-Tomato-Tetranychus (Tetranychus Ivani)

The spider mites (Tetranychus Ivani) are reared in the laboratory. Count the number of mites, collect the mites and place them on healthy young tomato plants.

Samples of the respective formulations of Examples 1 to 10 were diluted with water and then sprayed on On the plant.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining mites population was checked and the number of mites was counted. The results are listed in Table B.

The results in Table B show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of the target pest infestation.

Field trial 3-Tomato-Thrips (Thrips palm)

Thrips (Thrips palm) are raised in the laboratory. The number of thrips was counted, the thrips were collected and then placed on healthy young tomato plants.

Samples of the formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining thrips population was checked and the number of remaining thrips was counted. The results are listed in Table C.

The results in Table C show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field Trial 4-Tomato-Moth (Liriomyza sativae)

The larvae of the moth (Liriomyza sativae) are reared in the laboratory. The number of larvae is counted, the larvae are collected and then placed on healthy young tomato plants.

Samples of the formulations of Examples 1 to 10 were diluted in 100 L of water and then sprayed on the plants. The spray was applied at a volume rate of 1000 L/ha.

Put the treated plants at a temperature of 21°C to 25°C and 80% relative air humidity Keep in the room for 10 days, then check the remaining larvae population and count the number of larvae. The results are listed in Table D.

The results in Table D show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 5-orange-aphids (large orange aphid)

Raise aphids (large orange aphid) in the laboratory. The number of aphids was counted, the aphids were collected and then placed on healthy young orange plants.

Samples of the respective formulations of Examples 1 to 10 were diluted with 100 L of water and then sprayed on the plants. The spray was applied at a volume rate of 2000 L/ha.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days. After that, the remaining aphids population was checked and the remaining aphids were Number count. The results are listed in Table E.

The results in Table E show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 6-Orange-Citrus leaf miner (Citrus leaf miner)

The citrus leaf miner (Citrus leaf miner) is raised in the laboratory. Count the number of insects, collect the insects and place them on healthy young orange plants.

The samples of the formulations of Examples 1 to 10 were diluted with 100 L of water and then sprayed on the plants. The spray was applied at a volume rate of 2500 L/ha.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining citrus leaf miner population was checked and the number of remaining insects was counted. The results are listed in Table F.

The results in Table F show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field Test 7-Pomelo-Tetranychus urticae (Tetranychus urticae)

The spider mites (Tetranychus urticae) are reared in the laboratory. Count the number of mites, collect the mites and place them on healthy young pomelo plants.

The samples of the formulations of Examples 1 to 10 were diluted with 100 L of water and then sprayed on the plants. The spray was applied at a volume rate of 3000 L/ha.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining population was checked and the number of mites was counted. The results are listed in Table G.

The results in Table G show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of the target pest infestation.

Field trial 8-pistachio-European red mite (Panoonychus elm)

The European red mite (panonychus elm) is raised in the laboratory. Count the number of mites, collect the mites and place them on healthy young pistachio plants.

Samples of the formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining population was checked and the number of mites was counted. The results are listed in Table H.

The results in Table H show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in treating the infestation of target pests.

Field Test 9-Pistachio-Psylla pistachios (Psylla pistachio)

The pistachio psyllids (Psylla pistachios) are kept in the laboratory. Count the number of insects, collect them and place them on healthy young pistachio plants.

Samples of the formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining insect population was checked and the number of insects was counted. The results are listed in Table I.

The results in Table I show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 10-cotton-aphids (cotton aphid)

Raise aphids (cotton aphid) in the laboratory. The number of aphids was counted, the aphids were collected and then placed on healthy cotton young plants.

Samples of the formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining aphids population was checked and the number of aphids was counted. The results are listed in Table J.

The results in Table J show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 11-Cotton-Thrips (Western Flower Thrips)

Thrips (Western flower thrips) are raised in the laboratory. The number of thrips was counted, the thrips were collected and then placed on healthy young cotton plants.

Samples of the formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining thrips population was checked and the number of thrips was counted. The results are listed in Table K.

The results in Table K show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of the target pest infestation.

Field trial 12-coffee-leaf miner (Coffee leaf miner)

The leaf miner (coffee leaf miner) is raised in the laboratory. Count the number of insects, collect leaf miners and place them on healthy young coffee plants.

Samples of the respective formulations of Examples 1 to 10 were diluted and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining leaf miner population was checked and the number of leaf miners was counted. The results are listed in Table L.

The results in Table L show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 13-melon-whitefly (whitefly type B)

Whitefly (Whitefly type B) is raised in the laboratory. Count the number of insects, collect the insects and place them on healthy young melon plants.

Samples of the respective formulations of Examples 1 to 10 were diluted and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining insect population was checked and the number of insects was counted. The results are listed in Table M.

The results in Table M show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 14-potato-aphids (Myzus persicae)

Raise aphids (Myzus persicae) in the laboratory. The number of aphids was counted, the aphids were collected and then placed on healthy young potato plants.

Samples of the respective formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining aphids population was checked and the number of aphids was counted. The results are listed in Table N.

The results in Table N show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 15-Red pepper-Thrips (Thrips palm)

Thrips (Thrips palm) are raised in the laboratory. Count the number of thrips, collect the thrips and place them on healthy young red pepper plants.

Samples of the respective formulations of Examples 1 to 10 were diluted and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining thrips population was checked and the number of thrips was counted. The results are listed in Table O.

The results in Table O show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 16-Soybean-Stinkbug (Hero American bug)

Raise stink bugs (hero american stink bug) in the laboratory. Count the number of insects, collect the insects and place them on healthy young soybean plants.

Samples of the respective formulations of Examples 1 to 10 were diluted and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining insect population was checked and the number of thrips was counted. The results are listed in Table P.

The results in Table P show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 17-Soybean-Tetranychus urticae (Tetranychus urticae)

The two-spotted spider mite (Tetranychus urticae) is raised in the laboratory. Count the number of insects, collect the insects and place them on healthy young soybean plants.

Samples of the formulations of Examples 1 to 10 were diluted and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining population was checked and the number of insects was counted. The results are listed in Table Q.

The results in Table Q show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in treating the target pest infestation.

Field Experiment 18-Soybean-Stinkbug (Pinkbug)

Raise stink bugs (Binbugs) in the laboratory. Count the number of insects, collect the insects and place them on healthy young soybean plants.

Samples of the formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining population was checked and the number of insects was counted. The results are listed in Table R.

The results in Table R show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of the target pest infestation.

Field Test 19-Soybean-Mite (Monoconychus Planckii)

Raise mites (Monoclonus Planckii) in the laboratory. Count the number of insects, collect mites and place them on healthy young soybean plants.

Samples of the respective formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining population was checked and the remaining insects were counted. The results are listed in Table S.

The results in Table S show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field Test 20-Orange-Asian Citrus Psyllid (Psyllus citrus)

Raise Asian citrus psyllids (Citrus psyllids) in the laboratory. Count the number of insects, collect the insects and place them on healthy young orange plants.

The samples of the formulations of Examples 1 to 10 were diluted with 100 L of water and then sprayed on the plants. The spray was applied at a volume rate of 2500 L/ha.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days. Afterwards, check the remaining population of Asian citrus psyllids and count the number. The results are listed in Table T.

The results in Table T show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field trial 21-Melon-Leafminer (Liriomyza huidobrensis)

The larvae of leaf miner (Liriomyza huidobrensis) are kept in the laboratory. The number of larvae is counted, the larvae are collected and then placed on healthy young melon plants.

Samples of the respective formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days, after which the remaining larvae population was checked and the number of larvae was counted. The results are listed in Table U.

The results in Table U show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in the treatment of the target pest infestation.

Field trial 22-rose-Tetranychus (Tetranychus urticae)

The spider mites (Tetranychus urticae) are reared in the laboratory. Count the number of mites, collect the mites and place them on healthy young rose plants.

Samples of the formulations of Examples 1 to 10 were diluted with water and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days. Afterwards, check the remaining mites population and count the number of remaining mites. The results are listed in Table V.

The results in Table V show the synergistic effects of the new nicotine insecticide and ivermectin insecticide in the treatment of target pest infestation.

Field Test 23-Rose-Tetranychus (Tetranychus Ivani)

The spider mites (Tetranychus Ivani) are reared in the laboratory. Count the number of mites, collect the mites and place them on healthy young rose plants.

Samples of the respective formulations of Examples 1 to 10 were diluted and then sprayed on the plants.

The treated plants were kept in a greenhouse at 21°C to 25°C and 80% relative air humidity for 10 days. After that, check the remaining mites population and count the number of mites. The results are listed in Table W.

The results in Table W show the synergistic effect of the new nicotine insecticide and ivermectin insecticide in treating the infestation of target pests.

Claims (22)

An insecticidal composition comprising components: (A) at least one new nicotine insecticide; and (B) at least one ivermectin insecticide, wherein the new nicotine insecticide is idamide; wherein the The vermectin insecticide is selected from the group consisting of abastin and inmectin; and the weight ratio of component (A) to component (B) is from 10.7:1 to 15:1. The insecticidal composition described in item 1 of the scope of the patent application, wherein the component (B) comprises abatin. The insecticidal composition according to item 1 or 2 of the scope of the patent application, wherein component (A) is present in an amount of at least 1% or from about 1% to about 75% by weight of the composition. The insecticidal composition according to item 1 or 2 of the scope of the patent application, wherein component (B) is present in an amount of at least 0.2% or from about 1% to about 50% by weight of the composition. The insecticidal composition described in item 1 of the scope of the patent application, wherein the components (A) and (B) of the composition are: (A) idamide and (B) abatine; or (A) benefit Dalamine and (B) inmectin. The insecticidal composition according to item 1 or 2 of the scope of the patent application, wherein the composition is in solution (SL), emulsion (EC), water-based emulsion (EW), oil-based suspension (OD), seed treatment suspension (FS), water-dispersible granules (WG), water-soluble granules (SG), water-dispersible powder (WP), water-soluble powder (SP), granules (GR), capsule granules (CG), In the form of fine granules (FG), large granules (GG), aqueous suspension emulsion (SE), microcapsule suspension (CS), microgranules (MG) or aqueous suspension (SC). A combination of (A) at least one new nicotine insecticide and (B) at least one ivermectin insecticide is used to prevent, control and/or treat insect infestation in plants, plant parts and/or their surrounding environment The use of; wherein the new nicotine insecticide is idamide; wherein the ivermectin insecticide is selected from the group consisting of abatin and inmitin; and wherein the component (A) and the component (B) are The weight ratio is from 10.7:1 to 15:1. The use as described in item 7 of the scope of the patent application, wherein the component (B) contains abatin. The use described in item 7 of the scope of the patent application, wherein the component (A) and the component (B) are: (A) idamide and (B) abatine; or (A) idamide and (B) Inmetine. The use described in item 7 or 8 of the scope of the patent application, wherein the component (A) and the component (B) are applied consecutively and/or simultaneously. The use as described in item 7 or 8 of the scope of patent application, wherein the composition described in any one of items 1 to 6 of the scope of patent application is used. The use according to item 7 or 8 of the scope of the patent application, wherein the plant is selected from fruits, Cucurbitaceae, citrus fruits, vegetables, coffee, fiber plants, legumes and ornamental plants. The use described in item 12 of the scope of patent application, wherein the plant is selected from potato, coffee, citrus, melon, red pepper, soybean, tomato, cotton, pistachio, rose. Such as the use described in item 7 or 8 of the scope of patent application, wherein the insect infestation is caused by the following items: ‧Aphids on tomatoes; tea mites; beetles; leafhoppers; leaf miners (Liriomyza leafminers); Tetranychus mites (Tetranychus urticae, Tetranychus Evans); Thrips (Thrips palm); Tomato pinworms; Tomato psyllids; Tomato spiny skin mites; Whitefly; or moths (Tomato spot Liriomyza); ‧Aphids on the genus Citrus (Citrus aphid); Asian citrus psyllid (Citrus psyllid); Gnat; Tea mites; Orange bud mite; Citrus leaf miner (Citrus leaf miner); Citrus root Weevil (larval complex); Citrus rust mite; Citrus thrips; Leafhopper/Marksman; Leaf miner; Mealbug; Scale insect; Tetranychus urticae (Tetranychus urticae); Whitefly; Thrips; or Tetranychus; ‧ aphids on pistachios (except black pecan aphids); European red mites (panonychus elm); two-spotted spider mites; whitefly; pistachio psyllids (pistachio carina); or spider mites; ‧Aphids on cotton (cotton aphid); or thrips (Western flower thrips); ‧leaf miners on coffee (coffee leaf miners); ‧whiteflies on melon (whitefly type B); or Leaf insect (Liriomyza huidobrensis); ‧Aphids on potato (Myzus persicae); or leaf miner (Liriomyza huidobrensis); ‧Thrips on red pepper (Thrips palm); ‧Stinkbug on soybeans (Hero American bug); Tetranychus urticae (Tetranychus urticae); Stinkbug (Tetranychus urticae); Or mites (Monoconychus Planckii); or Tetranychus urticae on roses (Tetranychus urticae, Tetranychus Ivansi ). A method for controlling insect infestation in plants, plant parts and/or their surrounding environment, the method comprising applying (A) at least a new nicotine insecticide to the plants, plant parts and/or their surrounding environment (B) at least one ivermectin insecticide; wherein the new nicotine insecticide is idamide; wherein the ivermectin insecticide is selected from the group consisting of abatin and inmeter; and wherein the component ( The weight ratio of A) to the component (B) is from 10.7:1 to 15:1. The method described in item 15 of the scope of patent application, wherein component (B) contains Abba Ting. The method described in item 15 of the scope of the patent application, wherein the component (A) and the component (B) are: (A) idamide and (B) abatine; or (A) idamide and (B) Inmetine. The method described in item 15 or 16 of the scope of the patent application, wherein the component (A) and the component (B) are applied consecutively and/or simultaneously. The method described in item 15 or 16 of the scope of patent application, wherein the composition described in any one of items 1 to 6 of the scope of patent application is used. The method according to item 15 or 16, wherein the plants are selected from fruits, cucurbitaceae, citrus fruits, vegetables, coffee, fiber plants, legumes and ornamental plants. The method described in item 20 of the scope of patent application, wherein the plants are selected from potato, coffee, citrus, melon, red pepper, soybean, tomato, cotton, pistachio, rose. Such as the method described in item 15 or 16 of the scope of patent application, wherein the insect infestation is caused by the following: ‧ aphids on tomato; tea mites; beetles; leafhoppers; leaf miners of the genus Liriomyza; spider mites ( Tetranychus urticae, Tetranychus Ivanii); Thrips (Thrips palm); Tomato pinworms; Tomato psyllids; Tomato spiny skin mites; Whitefly; or Moths (Liriomyza tomato); ‧On Citrus Aphid (Citrus aphid); Asian citrus psyllid (Citrus psyllid); Gnat; Tea mites; Citrus sprout mite; Citrus leaf miner (Citrus leaf miner); Citrus root weevil (larval complex); Citrus rust mite; citrus thrips; leafhoppers/ sharpshooter insects; leaf miners; mealybugs; scale insects; two-spotted spider mites (Tetranychus urticae); whiteflies; thrips; or spider mites; Aphids (except black pecan aphids); European red mite Mites); two-spotted spider mite; whitefly; pistachio psyllid (Psylla spp.); or spider mite; ‧aphids on cotton (cotton aphid); or thrips (Western flower thrips); ‧on coffee Leaf miner (Coffee leaf miner); ‧Whitefly on melon (Whitefly type B); or Leafminer (Liriomyza huidobrensis); ‧Aphids on potato (Myzus persicae); or Leafminer (Liriomyza huidobrensis); ‧Thrips on red peppers (Thrips palm); ‧Stink bugs on soybeans (Hero American bug); Tetranychus urticae (Tetranychus urticae); Stink bugs (Lepidoptera); or Mite (Planck's monoclawed mite); or ‧ Tetranychus on roses (Tetranychus urticae, Tetranychus Ivani).