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TW201611832A - Icaritin compound and application thereof - Google Patents

Icaritin compound and application thereof

Info

Publication number
TW201611832A
TW201611832A TW104130599A TW104130599A TW201611832A TW 201611832 A TW201611832 A TW 201611832A TW 104130599 A TW104130599 A TW 104130599A TW 104130599 A TW104130599 A TW 104130599A TW 201611832 A TW201611832 A TW 201611832A
Authority
TW
Taiwan
Prior art keywords
icaritin
compound
application
provides
present
Prior art date
Application number
TW104130599A
Other languages
English (en)
Other versions
TWI632907B (zh
Inventor
Kun Meng
Bo Zhang
Cheng Tang
xian-da Yuan
Original Assignee
Beijing Shenogen Pharma Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Shenogen Pharma Group Ltd filed Critical Beijing Shenogen Pharma Group Ltd
Publication of TW201611832A publication Critical patent/TW201611832A/zh
Application granted granted Critical
Publication of TWI632907B publication Critical patent/TWI632907B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Saccharide Compounds (AREA)
  • Epoxy Compounds (AREA)
TW104130599A 2014-09-16 2015-09-16 一種阿可拉定化合物晶型以及該化合物晶型的用途 TWI632907B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
??201410472018.1 2014-09-16
CN201410472018.1A CN104230870A (zh) 2014-09-16 2014-09-16 一种阿可拉定化合物以及该化合物的用途
CN201510419782.7A CN104945364B (zh) 2014-09-16 2015-07-16 一种阿可拉定化合物以及该化合物的用途
??201510419782.7 2015-07-16

Publications (2)

Publication Number Publication Date
TW201611832A true TW201611832A (en) 2016-04-01
TWI632907B TWI632907B (zh) 2018-08-21

Family

ID=52219873

Family Applications (1)

Application Number Title Priority Date Filing Date
TW104130599A TWI632907B (zh) 2014-09-16 2015-09-16 一種阿可拉定化合物晶型以及該化合物晶型的用途

Country Status (2)

Country Link
CN (2) CN104230870A (zh)
TW (1) TWI632907B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105476957B (zh) * 2014-12-18 2021-04-20 北京珅奥基医药科技有限公司 一种阿可拉定注射剂及其制备方法和用途
CN110699263B (zh) * 2019-10-29 2021-05-11 浙江工业大学 黑曲霉yh-6及其应用于提高淫羊藿中淫羊藿素的含量
CN116410166B (zh) * 2021-12-29 2025-11-28 山东新时代药业有限公司 一种淫羊藿苷元丙酮溶剂合物及其制备方法
CN116410168B (zh) * 2021-12-29 2025-12-05 山东新时代药业有限公司 一种淫羊藿苷元一水合物晶体及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101302548B (zh) * 2007-05-09 2011-04-13 北京珅奥基医药科技有限公司 淫羊藿素的制备方法
CN101200743B (zh) * 2007-12-17 2010-12-15 北京珅奥基医药科技有限公司 水合淫羊藿素的制备方法
CN102038673B (zh) * 2009-10-20 2012-07-25 北京珅奥基医药科技有限公司 羟基苯并吡喃酮类化合物在制备治疗白血病药物中的应用
CN103936705B (zh) * 2014-05-05 2015-10-21 北京盛诺基医药科技有限公司 阿可拉定化合物的晶型、含有该晶型的药物及用途

Also Published As

Publication number Publication date
TWI632907B (zh) 2018-08-21
CN104945364B (zh) 2017-03-08
CN104230870A (zh) 2014-12-24
CN104945364A (zh) 2015-09-30

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