[go: up one dir, main page]

TW200626136A - Low oil emulsion compositions for delivering taxoids and other insoluble drugs - Google Patents

Low oil emulsion compositions for delivering taxoids and other insoluble drugs

Info

Publication number
TW200626136A
TW200626136A TW094133774A TW94133774A TW200626136A TW 200626136 A TW200626136 A TW 200626136A TW 094133774 A TW094133774 A TW 094133774A TW 94133774 A TW94133774 A TW 94133774A TW 200626136 A TW200626136 A TW 200626136A
Authority
TW
Taiwan
Prior art keywords
taxoids
delivering
oil emulsion
low oil
insoluble drugs
Prior art date
Application number
TW094133774A
Other languages
English (en)
Inventor
Andrew Xian Chen
Original Assignee
Andrew Xian Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Andrew Xian Chen filed Critical Andrew Xian Chen
Publication of TW200626136A publication Critical patent/TW200626136A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
TW094133774A 2004-09-28 2005-09-28 Low oil emulsion compositions for delivering taxoids and other insoluble drugs TW200626136A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/952,243 US8557861B2 (en) 2004-09-28 2004-09-28 Low oil emulsion compositions for delivering taxoids and other insoluble drugs

Publications (1)

Publication Number Publication Date
TW200626136A true TW200626136A (en) 2006-08-01

Family

ID=36099405

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094133774A TW200626136A (en) 2004-09-28 2005-09-28 Low oil emulsion compositions for delivering taxoids and other insoluble drugs

Country Status (14)

Country Link
US (1) US8557861B2 (zh)
EP (1) EP1804765A4 (zh)
JP (1) JP2008514720A (zh)
KR (1) KR20070063023A (zh)
CN (1) CN101094646A (zh)
AU (1) AU2005289398A1 (zh)
CA (1) CA2581635A1 (zh)
IL (1) IL182069A0 (zh)
MX (1) MX2007003727A (zh)
NO (1) NO20071651L (zh)
RU (1) RU2007116149A (zh)
TW (1) TW200626136A (zh)
WO (1) WO2006037089A2 (zh)
ZA (1) ZA200702536B (zh)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8557861B2 (en) 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
US20060067953A1 (en) * 2004-09-29 2006-03-30 Conforma Therapeutics Corporation Oral pharmaceutical formulations and methods for producing and using same
ES2784794T3 (es) * 2005-08-31 2020-10-01 Abraxis Bioscience Llc Composiciones que comprenden agentes farmacéuticos poco solubles en agua y agentes antimicrobianos
TWI376239B (en) * 2006-02-01 2012-11-11 Andrew Xian Chen Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
WO2007134354A1 (de) * 2006-05-23 2007-11-29 Ebewe Pharma Ges.M.B.H. Nfg. Kg Pharmazeutische formulierung
WO2008013785A2 (en) 2006-07-24 2008-01-31 Singh-Broemer And Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
AU2007299738B2 (en) 2006-09-20 2013-03-28 The Board Of Regents Of The University Of Texas System Methods for delivering volatile anesthetics for regional anesthesia and/or pain relief
WO2008042841A2 (en) * 2006-10-02 2008-04-10 Dr. Reddy's Laboratories Limited Docetaxel compositions
EP2025333A1 (en) * 2007-08-14 2009-02-18 Pharmatex Italia Srl Injectable pharmaceutical formulation of taxoids
CN101396354B (zh) * 2007-09-30 2010-12-01 江苏恒瑞医药股份有限公司 一种稳定的塔三烷类化合物液体组合物及其制备方法和其应用
FR2922107B1 (fr) * 2007-10-10 2010-02-26 Aventis Pharma Sa Nouvelles compositions a base de taxoides
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
AU2009206391A1 (en) * 2008-01-22 2009-07-30 Board Of Regents, The University Of Texas System Volatile anesthetic compositions and methods of use
AU2014277860A1 (en) * 2008-01-22 2015-01-22 Board Of Regents, The University Of Texas System Volatile anesthetic compositions and methods of use
CN102014961B (zh) 2008-01-22 2017-10-13 得克萨斯大学体系董事会 用于局部麻醉和/或疼痛缓解的含有萃取溶剂的挥发性麻醉剂组合物
BRPI0821895A2 (pt) * 2008-04-04 2014-10-07 Robert Shorr Composiçao farmacêutica, método de tratamento ou prevenção de uma doença, uma condição e sintomas das mesmas em animais de sangue quente, incluindo seres humanos, método de preparação da composição farmacêutica e método para diagnosticar uma doença, condição, síndrome.
JP5635504B2 (ja) * 2008-07-23 2014-12-03 ブハラット セルムズ アンド ヴァクシンズ リミテッド 安定した注射可能な水中油型ドセタキセルナノエマルション
FR2934955B1 (fr) * 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2934953B1 (fr) 2008-08-14 2011-01-21 Commissariat Energie Atomique Nanoemulsions de nanocristaux
EP2204167A1 (en) 2009-01-05 2010-07-07 Azad Pharma AG Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) * 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
US20110071090A1 (en) * 2009-03-11 2011-03-24 Stable Solutions Llc Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle
EP2662472B1 (de) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Verfahren zur Beschichtung einer Oberfläche eines Bauteils
WO2010129686A1 (en) 2009-05-05 2010-11-11 Vapogenix, Inc. Novel formulations of volatile anesthetics and methods of use for reducing inflammation
WO2010133294A2 (de) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapter, inhalationseinrichtung und zerstäuber
CN102038636B (zh) * 2009-10-23 2014-08-13 天士力控股集团有限公司 一种含有螯合剂的紫杉烷类药物溶液及其制备方法
CN102038635A (zh) 2009-10-23 2011-05-04 天津天士力集团有限公司 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法
CN102048688B (zh) * 2009-10-29 2014-03-05 中国医学科学院药物研究所 以胆固醇复合物为中间载体的紫杉醇亚微乳
JP5715640B2 (ja) 2009-11-25 2015-05-13 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
TWI438009B (zh) * 2010-02-19 2014-05-21 Teikoku Pharma Usa Inc 紫杉烷前－乳劑調配物及其製造與使用之方法
US10703722B2 (en) 2010-04-27 2020-07-07 Calcimedica, Inc. Compounds that modulate intracellular calcium
JP5824511B2 (ja) * 2010-05-03 2015-11-25 テイコク ファーマ ユーエスエー インコーポレーテッド 非水タキサンプロエマルジョン配合物ならびにそれを調製および使用する方法
WO2011153513A2 (en) * 2010-06-03 2011-12-08 Latitude Pharma Nanoemulsion composition containing vitamin k
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
BR112013003934A2 (pt) * 2010-08-20 2016-06-07 Reddys Lab Ltd Dr depot de fosfolipídeos
JP2012051823A (ja) * 2010-08-31 2012-03-15 Fujifilm Corp 難容性薬物含有水中油型乳化組成物及びその製造方法
CN101926757B (zh) * 2010-09-01 2013-01-02 北京大学 一种难溶性药物的液体组合物及其制备方法
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
US8586527B2 (en) 2011-10-20 2013-11-19 Jaipal Singh Cerivastatin to treat pulmonary disorders
EP2797585A4 (en) * 2011-12-29 2015-10-07 Latitude Pharmaceuticals Inc STABILIZED GLUCAGONNANOULULSIONS
RU2681835C2 (ru) 2012-01-23 2019-03-13 Сейдж Терапьютикс, Инк. Лекарственные формы нейроактивных стероидов и способы лечения нарушений цнс
US20150018320A1 (en) * 2012-02-29 2015-01-15 B. Braun Melsungen Ag Hormone Containing Emulsion Comprising Krill Phospholipids
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
IN2014MN02213A (zh) 2012-05-10 2015-07-10 Painreform Ltd
IL294306B2 (en) 2012-08-21 2024-01-01 Sage Therapeutics Inc Methods of treating epilepsy or status epilepticus
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
MX2015004703A (es) * 2012-10-16 2015-10-12 Genspera Inc Composiciones cancerigenas inyectables.
KR101951933B1 (ko) * 2013-03-12 2019-02-25 주식회사 아리바이오 라이소포스파티딜콜린 또는 이의 유도체를 포함하는 지질나노물질 및 이의 제조방법
US20140275261A1 (en) * 2013-03-15 2014-09-18 Dr. Reddy's Laboratories, Inc. Diclofenac parenteral compositions
CN103301062A (zh) * 2013-06-03 2013-09-18 四川百利药业有限责任公司 一种中长链脂肪乳注射液的制备方法
WO2015018904A1 (en) 2013-08-09 2015-02-12 Boehringer Ingelheim International Gmbh Nebulizer
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
KR101439898B1 (ko) * 2013-08-12 2014-09-17 박승재 상황버섯을 이용한 고품질 코코넛오일의 제조방법
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
BR112016023983B1 (pt) 2014-05-07 2022-10-18 Boehringer Ingelheim International Gmbh Contentor para um nebulizador, nebulizador para um fluido e método para conectar um contentor a um dispositivo indicador
KR102730574B1 (ko) 2014-05-07 2024-11-15 베링거 인겔하임 인터내셔날 게엠베하 분무기, 표시 디바이스 및 컨테이너
WO2016069409A1 (en) 2014-10-27 2016-05-06 Latitude Pharmaceuticals, Inc. Parenteral glucagon formulations
CN104473869A (zh) * 2014-11-20 2015-04-01 北京京科泰来科技有限公司 一种艾司洛尔脂肪乳及其制备方法
ES2922815T3 (es) * 2015-02-06 2022-09-20 Woodstock Sterile Solutions Inc Preparación de una emulsión de aceite en agua para formulaciones farmacéuticas estabilizadas con polímeros
AU2016224993B2 (en) 2015-02-27 2019-11-21 Calcimedica, Inc. Pancreatitis treatment
CN107683134B (zh) * 2015-05-15 2021-02-23 珠海贝海生物技术有限公司 多西他赛及人血清白蛋白复合物
EP3463299A4 (en) * 2016-06-07 2020-01-15 Targagenix, Inc. TAXOID NANOEMULSION COMPOSITIONS, AND METHODS OF USE THEREOF FOR TARGETING CANCER CELLS AND CANCER STEM CELLS
EP3573610A4 (en) * 2017-01-26 2021-01-13 Calcimedica, Inc. CRAC CHANNEL INHIBITOR COMPOSITIONS
US12522589B2 (en) 2020-11-13 2026-01-13 Calcimedica, Inc. Synthesis of CRAC channel inhibitors
WO2024206239A1 (en) * 2023-03-24 2024-10-03 Insitu Biologics, Inc. Sustained release cancer therapeutics formulations

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1792410B2 (de) * 1967-09-01 1980-03-13 Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm Arzneimittelzubereitung zur intravenösen Injektion
US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
EP0556394B1 (en) * 1990-11-06 2002-06-19 Nippon Shinyaku Company, Limited Lyophilized preparation and production thereof
IL101007A (en) * 1992-02-18 1997-08-14 Pharmos Ltd Dry stable compositions prepared by lyophilization
CA2086874E (en) * 1992-08-03 2000-01-04 Renzo Mauro Canetta Methods for administration of taxol
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US5478860A (en) * 1993-06-04 1995-12-26 Inex Pharmaceuticals Corp. Stable microemulsions for hydrophobic compound delivery
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
FR2718963B1 (fr) * 1994-04-25 1996-05-24 Rhone Poulenc Rorer Sa Nouvelle composition pharmaceutique à base de taxoïdes.
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US5635536A (en) 1994-12-07 1997-06-03 Pharmacia & Upjohn Aktiebolag Emulsion suitable for administering a sphingolipid
US6231600B1 (en) * 1995-02-22 2001-05-15 Scimed Life Systems, Inc. Stents with hybrid coating for medical devices
US5977172A (en) * 1995-09-13 1999-11-02 Nippon Shinyaku Co., Ltd. PGE1 -containing-freeze dried preparation and process for the production thereof
US6245349B1 (en) * 1996-02-23 2001-06-12 éLAN CORPORATION PLC Drug delivery compositions suitable for intravenous injection
DE19612566C2 (de) 1996-03-29 1999-02-25 Siemens Ag Vorrichtung zum Verhindern von Doppelabzügen
US5660858A (en) 1996-04-03 1997-08-26 Research Triangle Pharmaceuticals Cyclosporin emulsions
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
GB9715759D0 (en) 1997-07-26 1997-10-01 Danbiosyst Uk New emulsion formulations
US20020006613A1 (en) * 1998-01-20 2002-01-17 Shyjan Andrew W. Methods and compositions for the identification and assessment of cancer therapies
WO1999039696A1 (en) * 1998-02-10 1999-08-12 Sicor Inc. Propofol composition containing sulfite
US6979456B1 (en) * 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
US7030155B2 (en) * 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
CA2337445A1 (en) 1998-07-16 2000-01-27 Sumitomo Pharmaceuticals Co., Ltd. Preparations for immunotherapy for cancer having bacterial somatic constituent as the active ingredient
CA2338031C (en) * 1998-07-17 2006-12-05 Sankaram Bhima Mantripragada Biodegradable compositions for the controlled release of encapsulated substances
DE19843968A1 (de) 1998-09-24 2000-04-13 Hans Dietl Taxane enthaltende pharmazeutische Zubereitung zur intravenösen Applikation und Verfahren zu ihrer Herstellung
US6028108A (en) * 1998-10-22 2000-02-22 America Home Products Corporation Propofol composition comprising pentetate
US6140373A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6455280B1 (en) * 1998-12-22 2002-09-24 Genset S.A. Methods and compositions for inhibiting neoplastic cell growth
DE19900054A1 (de) * 1999-01-04 2000-07-06 Hans Dietl Taxane enthaltende stabile und sterile Emulsion und Verfahren zu ihrer Herstellung
JP2000212067A (ja) 1999-01-19 2000-08-02 Towa Yakuhin Kk 薬物含有エマルジョン製剤
TW422706B (en) * 1999-07-01 2001-02-21 Wang Iz Rung An oil-in-water emulsion type of paclitaxel
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
US6136846A (en) * 1999-10-25 2000-10-24 Supergen, Inc. Formulation for paclitaxel
WO2002053154A1 (en) 2000-12-28 2002-07-11 Daiichi Pharmaceutical Co., Ltd. Pharmaceutical emulsion preparation
US20030099674A1 (en) * 2001-08-11 2003-05-29 Chen Andrew X. Lyophilized injectable formulations containing paclitaxel or other taxoid drugs
US6858227B1 (en) * 2001-11-21 2005-02-22 Sonus Pharmaceuticals, Inc. Vitamin E conjugates
JP2005249110A (ja) 2004-03-05 2005-09-15 Daijiro Nakamura 回転出力装置
ES2283756T3 (es) 2002-03-01 2007-11-01 Novagali Pharma Sa Sistemas autoemulsionantes de administracion de farmaco para taxoides.
EP1585548B1 (en) * 2002-12-09 2018-06-27 Abraxis BioScience, LLC Compositions and methods of delivery of pharmacological agents
EP1510206A1 (en) 2003-08-29 2005-03-02 Novagali Pharma SA Self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs
US7713440B2 (en) * 2003-10-08 2010-05-11 Lyotropic Therapeutics, Inc. Stabilized uncoated particles of reversed liquid crystalline phase materials
EP1682552B1 (en) * 2003-10-29 2010-06-30 Sonus Pharmaceuticals, Inc. Tocopherol-modified therapeutic drug compounds
WO2005065676A1 (ja) 2004-01-09 2005-07-21 Otsuka Pharmaceutical Factory, Inc. パクリタキセルまたはドセタキセルを含む脂肪乳剤
JP2005225818A (ja) 2004-02-13 2005-08-25 Otsuka Pharmaceut Factory Inc パクリタキセル又はドセタキセルの医薬組成物
US7871632B2 (en) * 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
JP2008508302A (ja) 2004-07-28 2008-03-21 エスディー ファーマシューティカルズ インコーポレイティッド αコハク酸トコフェリル、そのアナログおよび塩の安定な注射用組成物
US8557861B2 (en) 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
WO2007075825A2 (en) * 2005-12-20 2007-07-05 Sonus Pharmaceuticals, Inc. Lipophilic anticancer drug compounds

Also Published As

Publication number Publication date
CN101094646A (zh) 2007-12-26
WO2006037089A2 (en) 2006-04-06
CA2581635A1 (en) 2006-04-06
IL182069A0 (en) 2007-07-24
US8557861B2 (en) 2013-10-15
EP1804765A4 (en) 2012-09-05
AU2005289398A1 (en) 2006-04-06
EP1804765A2 (en) 2007-07-11
US20060067952A1 (en) 2006-03-30
ZA200702536B (en) 2009-08-26
KR20070063023A (ko) 2007-06-18
MX2007003727A (es) 2007-06-05
JP2008514720A (ja) 2008-05-08
WO2006037089A3 (en) 2007-01-25
RU2007116149A (ru) 2008-11-10
NO20071651L (no) 2007-06-21

Similar Documents

Publication Publication Date Title
TW200626136A (en) Low oil emulsion compositions for delivering taxoids and other insoluble drugs
BRPI0717219B8 (pt) composição imunogênica, e, uso de uma composição imunogênica
BRPI0815828A2 (pt) Formulação de emulsão que impede interação através da interface água-óleo
BRPI0518228B8 (pt) inibidores de cinesina mitótica e uso dos mesmos
ZA200608200B (en) Microfluidized oil-in-water emulsions and vaccine compositions
BRPI0414840A (pt) método de download de arquivo de conteúdo e de recebimento de conteúdo adicional com uma janela e respectivo sistema de download de conteúdo, meios legìveis em computador e sistemas de computador
DE60131862D1 (de) Herstellung von vitaminemulsionen und konzentrate davon
PL387009A1 (pl) Kompozycje zawierające wytworzone przez metatezę nienasycone estry polioli
BR0310099A (pt) método para tratar dislipidemia ou uma doença associada com a dislipidemia
ATE538650T1 (de) Cannabinoid-rezeptor-antagonisten / inverse agonisten zur behandlung von übergewicht
ECSP077238A (es) Composiciones para entrega de drogas altamente solubles en agua
ECSP067062A (es) Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso
WO2006015120A3 (en) Stable injectable composition of alpha tocopheryl succinate, analogues and salts thereof
CY1116904T1 (el) Εμβολιο
ATE501705T1 (de) Antitranspirant-stick-zusammensetzungen
UA89315C2 (en) Butylbenzene phthalein intravenous emulsion
MX2008012224A (es) Limpiador de aparato dental.
EP2468772A3 (en) Antibodies to EGFL7 and methods for their use
ATE484273T1 (de) Niedermolekulare öl-in-wasser-silikonemulsion
NO20073762L (no) Visko-supplementsammensetning og fremgangsmater
DE502005006577D1 (de) 2-phenylethylbenzoat in kosmetischen öl-in-wasser-uv-lichtschutzemulsionen
DE502005006701D1 (de) Triterpenhaltiger oleogelbildner, triterpenhaltiges oleogel und verfahren zur herstellung eines triterpenhaltigen oleogels
CY1114497T1 (el) ΜΕΘΟΔΟΙ ΚΑΙ ΣΥΝΘΕΣΕΙΣ ΓΙΑ ΤΗΝ ΑΝΤΙΜΕΤΩΠΙΣΗ ΚΑΙ ΤΗΝ ΠΡΟΛΗΨΗ ΝΟΣΟΥ ΠΟΥ ΣΧΕΤΙΖΕΤΑΙ ΜΕ ΤΗΝ ΙΝΤΕΓΚΡΙΝΗ ανβ5
EA201001478A1 (ru) Вакцина
EA201291321A1 (ru) Способ разрушения эмульсий при добыче нефти с искусственным поддержанием давления пласта