SMT201400080B - Derivati di pirazinoossazepina - Google Patents

Derivati di pirazinoossazepina

Info

Publication number: SMT201400080B
Authority: SM; San Marino
Prior art keywords: pyrazinooxazepine; derivatives; pyrazinooxazepine derivatives
Prior art date: 2009-06-15

Application number

SM201400080T

Other languages

English (en)

Italian (it)

Inventor

Shigekazu Sasaki

Tomokazu Kusumoto

Izumi Nomura

Hironobu Maezaki

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-06-15

Filing date

2014-06-25

Publication date

2014-09-08

2014-06-25 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2014-09-08 Publication of SMT201400080B publication Critical patent/SMT201400080B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Child & Adolescent Psychology (AREA)
Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SM201400080T 2009-06-15 2014-06-25 Derivati di pirazinoossazepina SMT201400080B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2009142673		2009-06-15
PCT/JP2010/060408 WO2010147226A1 (en)	2009-06-15	2010-06-14	Pyrazinooxazepine derivatives

Publications (1)

Publication Number	Publication Date
SMT201400080B true SMT201400080B (it)	2014-09-08

Family

ID=42561089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SM201400080T SMT201400080B (it)	2009-06-15	2014-06-25	Derivati di pirazinoossazepina

Country Status (40)

Country	Link
US (4)	US9115139B2 (es)
EP (1)	EP2442870B1 (es)
JP (2)	JP5579262B2 (es)
KR (1)	KR101768234B1 (es)
CN (1)	CN102458579B (es)
AR (1)	AR077094A1 (es)
AU (1)	AU2010260847B2 (es)
BR (1)	BRPI1011502A2 (es)
CA (1)	CA2765239C (es)
CL (1)	CL2011003154A1 (es)
CO (1)	CO6491037A2 (es)
CR (1)	CR20120021A (es)
CY (1)	CY1115483T1 (es)
DK (1)	DK2442870T3 (es)
DO (1)	DOP2011000393A (es)
EA (1)	EA021079B1 (es)
EC (1)	ECSP12011603A (es)
ES (1)	ES2480275T3 (es)
GE (1)	GEP20146168B (es)
HR (1)	HRP20140589T1 (es)
IL (1)	IL216761A (es)
JO (1)	JO3087B1 (es)
MA (1)	MA33430B1 (es)
ME (1)	ME01835B (es)
MX (1)	MX2011013081A (es)
MY (1)	MY157497A (es)
NZ (1)	NZ597507A (es)
PE (1)	PE20121049A1 (es)
PL (1)	PL2442870T3 (es)
PT (1)	PT2442870E (es)
RS (1)	RS53414B (es)
SG (1)	SG176696A1 (es)
SI (1)	SI2442870T1 (es)
SM (1)	SMT201400080B (es)
TN (1)	TN2011000630A1 (es)
TW (2)	TW201529584A (es)
UA (1)	UA108357C2 (es)
UY (1)	UY32707A (es)
WO (1)	WO2010147226A1 (es)
ZA (1)	ZA201109370B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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US8158617B2 (en) *	2006-05-16	2012-04-17	Takeda Pharmaceutical Company Limited	Fused heterocyclic compound and use thereof
EP2442870B1 (en) *	2009-06-15	2014-04-16	Takeda Pharmaceutical Company Limited	Pyrazinooxazepine derivatives
US20130267500A1 (en)	2010-09-01	2013-10-10	Arena Pharmaceuticals, Inc.	5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level
JP2014201578A (ja) *	2013-04-09	2014-10-27	武田薬品工業株式会社	線維筋痛症治療剤
JP2014214132A (ja) *	2013-04-26	2014-11-17	武田薬品工業株式会社	ニコチン依存症の予防・治療剤
WO2015066344A1 (en)	2013-11-01	2015-05-07	Arena Pharmaceuticals, Inc.	5-ht2c receptor agonists and compositions and methods of use
WO2017026538A1 (en)	2015-08-07	2017-02-16	Takeda Pharmaceutical Company Limited	Production method of pyrazine
TW201729814A (zh)	2015-12-24	2017-09-01	武田藥品工業股份有限公司	固形製劑
US9985579B2 (en)	2016-04-12	2018-05-29	Preformed Line Products Co.	Mounting assembly for mounting a solar panel
WO2019131902A1 (ja) *	2017-12-27	2019-07-04	武田薬品工業株式会社	腹圧性尿失禁および便失禁の治療薬

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JP2992677B2 (ja)	1995-06-05	1999-12-20	武田薬品工業株式会社	骨形成促進医薬組成物
SE0002754D0 (sv)	2000-07-21	2000-07-21	Pharmacia & Upjohn Ab	New pharmaceutical combination formulation and method of treatment with the combination
CN1227237C (zh)	2000-11-20	2005-11-16	比奥维特罗姆股份公司	作为五羟色胺5－ht2受体拮抗剂的哌嗪基吡嗪化合物
WO2002083863A2 (en)	2001-04-17	2002-10-24	Sepracor, Inc.	Thiazole and other heterocyclic ligands and use thereof
SE0201544D0 (sv)	2002-05-17	2002-05-17	Biovitrum Ab	Novel compounds and thier use
DE60321606D1 (de)	2002-06-19	2008-07-24	Biovitrum Ab Publ	Piperazinylpyrazine als Modulatoren des Serotonin 5-HT2C Rezeptors
EA008148B1 (ru)	2002-06-19	2007-04-27	Биовитрум Аб	Новые соединения, их применение и получение
WO2004067008A1 (ja)	2003-01-28	2004-08-12	Takeda Pharmaceutical Company Limited	受容体作動薬
CL2004000826A1 (es)	2003-04-25	2005-03-04	Pfizer	Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129
PL2332921T3 (pl) *	2003-06-17	2016-08-31	Arena Pharm Inc	Chlorowodorek 8-chloro-1-metylo-2,3,4,5-tetrahydro-1H-3-benzazepiny
CA2888392A1 (en)	2003-06-17	2005-03-03	Arena Pharmaceuticals, Inc.	Processes for preparing 3-benzazepines
JP2006056881A (ja)	2004-07-21	2006-03-02	Takeda Chem Ind Ltd	縮合環化合物
DK1926712T3 (da)	2005-09-01	2009-11-09	Lilly Co Eli	6-Substituerede 2,3,4,5-tetrahydro-1H-benzo[D]azepiner som 5-HT2C-receptoragonister
FR2895259B1 (fr)	2005-12-22	2008-02-22	Urosphere Sas	Methodes de traitement des incontinences urinaires
US8158617B2 (en) *	2006-05-16	2012-04-17	Takeda Pharmaceutical Company Limited	Fused heterocyclic compound and use thereof
JP5497429B2 (ja) *	2007-03-07	2014-05-21	武田薬品工業株式会社	ベンゾオキサゼピン誘導体およびその用途
WO2009032754A2 (en)	2007-08-31	2009-03-12	Kalypsys, Inc.	Heterocyclodiazepine cannabinoid receptor modulators for treatment of disease
WO2009063993A1 (ja) *	2007-11-15	2009-05-22	Takeda Pharmaceutical Company Limited	縮合ピリジン誘導体およびその用途
EP2216023A4 (en)	2007-11-15	2013-03-13	Takeda Pharmaceutical	CONDENSED PYRIDINE DERIVATIVE AND ITS USE
JP5361733B2 (ja)	2007-11-15	2013-12-04	武田薬品工業株式会社	ピリドオキサゼピン誘導体およびその用途
EP2442870B1 (en) *	2009-06-15	2014-04-16	Takeda Pharmaceutical Company Limited	Pyrazinooxazepine derivatives
US8299103B2 (en)	2009-06-15	2012-10-30	Boehringer Ingelheim International Gmbh	Compounds which selectively modulate the CB2 receptor

2010
- 2010-06-14 EP EP10727154.6A patent/EP2442870B1/en active Active
- 2010-06-14 TW TW104112674A patent/TW201529584A/zh unknown
- 2010-06-14 PE PE2011002104A patent/PE20121049A1/es active IP Right Grant
- 2010-06-14 EA EA201270017A patent/EA021079B1/ru not_active IP Right Cessation
- 2010-06-14 MA MA34535A patent/MA33430B1/fr unknown
- 2010-06-14 CA CA2765239A patent/CA2765239C/en not_active Expired - Fee Related
- 2010-06-14 NZ NZ597507A patent/NZ597507A/xx not_active IP Right Cessation
- 2010-06-14 GE GEAP201012529A patent/GEP20146168B/en unknown
- 2010-06-14 RS RS20140373A patent/RS53414B/sr unknown
- 2010-06-14 JO JOP/2010/0194A patent/JO3087B1/ar active
- 2010-06-14 CN CN201080036178.1A patent/CN102458579B/zh not_active Expired - Fee Related
- 2010-06-14 AU AU2010260847A patent/AU2010260847B2/en not_active Ceased
- 2010-06-14 JP JP2012514674A patent/JP5579262B2/ja not_active Expired - Fee Related
- 2010-06-14 MX MX2011013081A patent/MX2011013081A/es active IP Right Grant
- 2010-06-14 ES ES10727154.6T patent/ES2480275T3/es active Active
- 2010-06-14 HR HRP20140589AT patent/HRP20140589T1/hr unknown
- 2010-06-14 MY MYPI2011006107A patent/MY157497A/en unknown
- 2010-06-14 PT PT107271546T patent/PT2442870E/pt unknown
- 2010-06-14 US US13/377,918 patent/US9115139B2/en not_active Expired - Fee Related
- 2010-06-14 BR BRPI1011502A patent/BRPI1011502A2/pt not_active Application Discontinuation
- 2010-06-14 WO PCT/JP2010/060408 patent/WO2010147226A1/en not_active Ceased
- 2010-06-14 TW TW099119242A patent/TWI542592B/zh not_active IP Right Cessation
- 2010-06-14 US US12/814,692 patent/US8318722B2/en not_active Expired - Fee Related
- 2010-06-14 UA UAA201200408A patent/UA108357C2/ru unknown
- 2010-06-14 UY UY0001032707A patent/UY32707A/es not_active Application Discontinuation
- 2010-06-14 SI SI201030641T patent/SI2442870T1/sl unknown
- 2010-06-14 DK DK10727154.6T patent/DK2442870T3/da active
- 2010-06-14 KR KR1020127000935A patent/KR101768234B1/ko not_active Expired - Fee Related
- 2010-06-14 SG SG2011090149A patent/SG176696A1/en unknown
- 2010-06-14 ME MEP-2014-81A patent/ME01835B/me unknown
- 2010-06-14 PL PL10727154T patent/PL2442870T3/pl unknown
- 2010-06-14 AR ARP100102101A patent/AR077094A1/es not_active Application Discontinuation
2011
- 2011-07-28 US US13/192,865 patent/US8324201B2/en not_active Expired - Fee Related
- 2011-07-28 US US13/192,845 patent/US8314088B2/en not_active Expired - Fee Related
- 2011-12-04 IL IL216761A patent/IL216761A/en not_active IP Right Cessation
- 2011-12-08 TN TNP2011000630A patent/TN2011000630A1/en unknown
- 2011-12-14 CL CL2011003154A patent/CL2011003154A1/es unknown
- 2011-12-14 DO DO2011000393A patent/DOP2011000393A/es unknown
- 2011-12-20 ZA ZA2011/09370A patent/ZA201109370B/en unknown
2012
- 2012-01-13 EC ECSP12011603 patent/ECSP12011603A/es unknown
- 2012-01-13 CO CO12004620A patent/CO6491037A2/es active IP Right Grant
- 2012-01-13 CR CR20120021A patent/CR20120021A/es unknown
- 2012-01-31 JP JP2012019274A patent/JP5579203B2/ja not_active Expired - Fee Related
2014
- 2014-06-25 SM SM201400080T patent/SMT201400080B/xx unknown
- 2014-07-11 CY CY20141100527T patent/CY1115483T1/el unknown

Also Published As

Publication number	Publication date
AU2010260847A1 (en)	2012-01-19
PL2442870T3 (pl)	2014-12-31
US8318722B2 (en)	2012-11-27
JP2012530051A (ja)	2012-11-29
ZA201109370B (en)	2012-10-31
HRP20140589T1 (hr)	2014-08-01
US8324201B2 (en)	2012-12-04
AU2010260847B2 (en)	2016-11-24
EP2442870B1 (en)	2014-04-16
US20110288291A1 (en)	2011-11-24
MX2011013081A (es)	2012-01-20
UY32707A (es)	2011-01-31
JO3087B1 (ar)	2017-03-15
US20120135979A1 (en)	2012-05-31
NZ597507A (en)	2013-09-27
US9115139B2 (en)	2015-08-25
ME01835B (me)	2014-12-20
ECSP12011603A (es)	2012-03-30
CN102458579B (zh)	2014-11-05
EA021079B1 (ru)	2015-03-31
EP2442870A1 (en)	2012-04-25
IL216761A (en)	2016-03-31
CY1115483T1 (el)	2017-01-04
GEP20146168B (en)	2014-09-25
SI2442870T1 (sl)	2014-07-31
EA201270017A1 (ru)	2012-07-30
CL2011003154A1 (es)	2012-06-15
ES2480275T3 (es)	2014-07-25
CR20120021A (es)	2012-03-06
AR077094A1 (es)	2011-08-03
CA2765239A1 (en)	2010-12-23
SG176696A1 (en)	2012-01-30
KR20120034734A (ko)	2012-04-12
KR101768234B1 (ko)	2017-08-14
HK1169623A1 (en)	2013-02-01
TW201529584A (zh)	2015-08-01
JP2012107032A (ja)	2012-06-07
CN102458579A (zh)	2012-05-16
MA33430B1 (fr)	2012-07-03
US20110282054A1 (en)	2011-11-17
BRPI1011502A2 (pt)	2016-03-22
CO6491037A2 (es)	2012-07-31
TWI542592B (zh)	2016-07-21
TW201109338A (en)	2011-03-16
WO2010147226A1 (en)	2010-12-23
IL216761A0 (en)	2012-02-29
PE20121049A1 (es)	2012-08-22
PT2442870E (pt)	2014-07-16
JP5579262B2 (ja)	2014-08-27
US20100317651A1 (en)	2010-12-16
TN2011000630A1 (en)	2013-05-24
RS53414B (sr)	2014-12-31
MY157497A (en)	2016-06-15
DK2442870T3 (da)	2014-06-30
UA108357C2 (xx)	2015-04-27
JP5579203B2 (ja)	2014-08-27
CA2765239C (en)	2018-08-07
US8314088B2 (en)	2012-11-20
DOP2011000393A (es)	2012-02-15

Publication	Publication Date	Title
SMT201600298B (it)	2016-11-10	Derivati n3-sostituiti-n1-solfonil-5- fluoropirimidinone
SMT201600198B (it)	2016-08-31	Derivati di 1,2,4-triazina-4-ammina
BRPI1013246A2 (pt)	2016-04-05	derivados de benzofuralina
BR112012002828A2 (pt)	2015-10-13	derivados de 5-fluorpirimidinona
ECSP12011999A (es)	2012-07-31	Derivados benzamida sustituidos
DK2397480T3 (da)	2013-09-02	Diazepindionderivat
DK2462134T3 (da)	2014-08-11	N1-sulfonyl-5-fluorpyrimidinonderivater
EP2433940A4 (en)	2012-10-10	SPIROIMIDAZOLONDERIVAT
DK2308877T3 (da)	2014-04-22	Imidazopyridin-2-on-derivater
BRPI1008774A2 (pt)	2016-03-08	espiroamida substituída
BRPI1013844A2 (pt)	2016-04-12	derivados de piridina-isoxazol
BRPI1008827A2 (pt)	2016-02-23	deisobutenizador
BRPI1014968A2 (pt)	2016-12-13	subalargador
SMT201600076B (it)	2016-04-29	Derivati di 2-osso-1-pirrolidinil imidazotiadiazolo
SMT201400080B (it)	2014-09-08	Derivati di pirazinoossazepina
DK2275414T3 (da)	2015-06-22	Cyclopentylacrylamidderivat
BRPI1014454A2 (pt)	2016-04-05	derivados de isoxazol-pirazol
DK2387580T3 (da)	2014-10-13	Deoxyactagardinderivater
BR112012002810A2 (pt)	2015-09-15	derivados de n1-acil-5-fluoropirimidinona
BR112012004964A2 (pt)	2016-04-05	girocóptero
BRPI1008070A2 (pt)	2016-03-15	tricianoboratos
EP2492266A4 (en)	2013-03-13	5-hydroxypyrimidine-4-carboxamide
BRPI1011416A2 (pt)	2016-03-15	derivados de antraquinova novos
EP2401281A4 (en)	2012-08-15	PYRIMIDINPYRIMIDOINDAZOLDERIVAT
ATE534634T1 (de)	2011-12-15	2-phenyl-4-cyclopropyl-pyrimidinderivate