SG158853A1 - Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue - Google Patents
Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissueInfo
- Publication number
- SG158853A1 SG158853A1 SG201000029-7A SG2010000297A SG158853A1 SG 158853 A1 SG158853 A1 SG 158853A1 SG 2010000297 A SG2010000297 A SG 2010000297A SG 158853 A1 SG158853 A1 SG 158853A1
- Authority
- SG
- Singapore
- Prior art keywords
- isolation
- identification
- mesenchymal tissue
- multipotent cells
- osteochondral mesenchymal
- Prior art date
Links
- 238000002955 isolation Methods 0.000 title abstract 4
- 210000002894 multi-fate stem cell Anatomy 0.000 title abstract 4
- 210000004027 cell Anatomy 0.000 abstract 3
- -1 CD49A Proteins 0.000 abstract 2
- 102100035248 Alpha-(1,3)-fucosyltransferase 4 Human genes 0.000 abstract 1
- 102100022749 Aminopeptidase N Human genes 0.000 abstract 1
- 102100032912 CD44 antigen Human genes 0.000 abstract 1
- 102100022002 CD59 glycoprotein Human genes 0.000 abstract 1
- 102100037904 CD9 antigen Human genes 0.000 abstract 1
- 102100025680 Complement decay-accelerating factor Human genes 0.000 abstract 1
- 102100037241 Endoglin Human genes 0.000 abstract 1
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 abstract 1
- 101001022185 Homo sapiens Alpha-(1,3)-fucosyltransferase 4 Proteins 0.000 abstract 1
- 101000757160 Homo sapiens Aminopeptidase N Proteins 0.000 abstract 1
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 abstract 1
- 101000897400 Homo sapiens CD59 glycoprotein Proteins 0.000 abstract 1
- 101000738354 Homo sapiens CD9 antigen Proteins 0.000 abstract 1
- 101000856022 Homo sapiens Complement decay-accelerating factor Proteins 0.000 abstract 1
- 101000881679 Homo sapiens Endoglin Proteins 0.000 abstract 1
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 abstract 1
- 101000994365 Homo sapiens Integrin alpha-6 Proteins 0.000 abstract 1
- 101001046686 Homo sapiens Integrin alpha-M Proteins 0.000 abstract 1
- 101001046677 Homo sapiens Integrin alpha-V Proteins 0.000 abstract 1
- 101000935043 Homo sapiens Integrin beta-1 Proteins 0.000 abstract 1
- 101000599852 Homo sapiens Intercellular adhesion molecule 1 Proteins 0.000 abstract 1
- 101000917858 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-A Proteins 0.000 abstract 1
- 101000917839 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-B Proteins 0.000 abstract 1
- 101001063392 Homo sapiens Lymphocyte function-associated antigen 3 Proteins 0.000 abstract 1
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 abstract 1
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 abstract 1
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 abstract 1
- 102100032816 Integrin alpha-6 Human genes 0.000 abstract 1
- 102100022338 Integrin alpha-M Human genes 0.000 abstract 1
- 102100022337 Integrin alpha-V Human genes 0.000 abstract 1
- 102100025304 Integrin beta-1 Human genes 0.000 abstract 1
- 102100037877 Intercellular adhesion molecule 1 Human genes 0.000 abstract 1
- 102100029185 Low affinity immunoglobulin gamma Fc region receptor III-B Human genes 0.000 abstract 1
- 102100030984 Lymphocyte function-associated antigen 3 Human genes 0.000 abstract 1
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 abstract 1
- 102000003729 Neprilysin Human genes 0.000 abstract 1
- 108090000028 Neprilysin Proteins 0.000 abstract 1
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 abstract 1
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 abstract 1
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Rheumatology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200402355A ES2313805B1 (es) | 2004-10-04 | 2004-10-04 | Identificacion y aislamiento de celulas multipotentes de tejido mesenquimal no osteocondral. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG158853A1 true SG158853A1 (en) | 2010-02-26 |
Family
ID=35457282
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013051040A SG192459A1 (en) | 2004-10-04 | 2005-10-04 | Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue |
| SG201000029-7A SG158853A1 (en) | 2004-10-04 | 2005-10-04 | Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013051040A SG192459A1 (en) | 2004-10-04 | 2005-10-04 | Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20060073124A1 (es) |
| EP (5) | EP3342857A1 (es) |
| JP (2) | JP2008515413A (es) |
| KR (1) | KR20070085294A (es) |
| CN (1) | CN101056974B (es) |
| AU (1) | AU2005291353A1 (es) |
| CA (1) | CA2583151C (es) |
| CY (1) | CY1116198T1 (es) |
| DK (1) | DK2292736T3 (es) |
| ES (2) | ES2313805B1 (es) |
| HU (1) | HUE025155T2 (es) |
| IL (1) | IL182441A (es) |
| PL (1) | PL2292736T3 (es) |
| PT (1) | PT2292736E (es) |
| SG (2) | SG192459A1 (es) |
| SI (1) | SI2292736T1 (es) |
| WO (1) | WO2006037649A1 (es) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7807458B2 (en) | 2003-01-30 | 2010-10-05 | The United States Of America As Represented By The Secretary Of The Department Of Veterans Affairs | Multilineage-inducible cells and uses thereof |
| EP1620827B1 (en) * | 2003-04-24 | 2010-06-02 | Koninklijke Philips Electronics N.V. | Non-invasive left ventricular volume determination |
| US7266519B2 (en) * | 2003-06-30 | 2007-09-04 | Qualcomm Incorporated | Billing system with authenticated wireless device transaction event data |
| ITRM20030376A1 (it) * | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| ES2313805B1 (es) | 2004-10-04 | 2009-12-23 | Cellerix, S.L. | Identificacion y aislamiento de celulas multipotentes de tejido mesenquimal no osteocondral. |
| CA2585980C (en) * | 2004-11-08 | 2017-09-26 | The Johns Hopkins University | Cardiac stem cells |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| EP3184630B1 (en) | 2005-09-23 | 2019-07-17 | TiGenix, S.A.U. | Cell populations having immunoregulatory activity, method for isolation and uses |
| EP1978977A4 (en) * | 2006-01-24 | 2010-03-17 | Christopher J Centeno | METHOD AND SYSTEM FOR ISOLATION AND TRANSPLANTATION OF MESENCHYMAL STEM CELLS FOR USE IN CLINICAL MEDIA |
| US20080025953A1 (en) * | 2006-07-25 | 2008-01-31 | Kiminobu Sugaya | Vigor Enhancement of Animals Via Administration of Stem Cells |
| KR100827660B1 (ko) | 2006-10-25 | 2008-05-07 | 대한민국 (식품의약품안전청장) | Ｃｄ9를 발현하는 인간 중간엽 줄기세포의 선별 및배양방법 |
| ES2441560T3 (es) | 2006-11-03 | 2014-02-05 | Aastrom Biosciences, Inc. | Poblaciones celulares mixtas para la reparación de tejidos y técnica de separación para el procesamiento celular |
| US20100093089A1 (en) * | 2006-11-09 | 2010-04-15 | Eduardo Marban | Dedifferentiation of adult mammalian cardiomyocytes into cardiac stem cells |
| FR2918073B1 (fr) * | 2007-06-27 | 2012-10-19 | Univ Paris Curie | Cellules fixatrices de cellules tumorales. |
| US9095562B2 (en) | 2007-07-05 | 2015-08-04 | Regenerative Sciences, Inc. | Methods and compositions for optimized expansion and implantation of mesenchymal stem cells |
| WO2009085969A2 (en) * | 2007-12-19 | 2009-07-09 | Regenerative Sciences, Llc | Compositions and methods to promote implantation and engrafment of stem cells |
| EP2257176B1 (en) | 2008-03-14 | 2013-09-18 | Regenerative Sciences, LLC | Compositions and methods for cartilage repair |
| GB0814249D0 (en) * | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
| AU2015268704B2 (en) * | 2008-08-04 | 2017-08-10 | Consejo Superior De Investigaciones Cientificas | Uses of mesenchymal stem cells |
| CN106995797B (zh) | 2008-08-18 | 2021-04-30 | 中胚有限公司 | 单克隆抗体stro-4 |
| KR20120006481A (ko) | 2008-12-05 | 2012-01-18 | 리제너러티브 사이언시즈, 엘엘씨 | 무혈관 조직의 복구를 촉진하기 위한 방법 및 조성물 |
| US20100168022A1 (en) * | 2008-12-11 | 2010-07-01 | Centeno Christopher J | Use of In-Vitro Culture to Design or Test Personalized Treatment Regimens |
| US20110054929A1 (en) * | 2009-09-01 | 2011-03-03 | Cell Solutions Colorado Llc | Stem Cell Marketplace |
| JP5810435B2 (ja) * | 2009-09-30 | 2015-11-11 | 国立大学法人 熊本大学 | 内胚葉細胞、腸管細胞又は膵細胞の検出方法 |
| US9113950B2 (en) | 2009-11-04 | 2015-08-25 | Regenerative Sciences, Llc | Therapeutic delivery device |
| US9249392B2 (en) | 2010-04-30 | 2016-02-02 | Cedars-Sinai Medical Center | Methods and compositions for maintaining genomic stability in cultured stem cells |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
| US20130071360A1 (en) | 2011-06-29 | 2013-03-21 | Biorestorative Therapies, Inc. | Brown Fat Cell Compositions and Methods |
| DK2634195T3 (en) * | 2012-03-01 | 2017-02-27 | Miltenyi Biotec Gmbh | Separation of living pristine neurons |
| EP2861238A4 (en) | 2012-06-05 | 2016-03-16 | Capricor Inc | OPTIMIZED METHODS FOR GENERATING CARDIAC STEM CELLS FROM CARDIAC TISSUE AND THEIR USE IN CARDIAC THERAPY |
| US9828603B2 (en) | 2012-08-13 | 2017-11-28 | Cedars Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
| EP3795678B1 (en) | 2013-04-19 | 2023-07-12 | Biorestorative Therapies, Inc. | Human brown adipose derived stem cells and uses |
| EP3027235A1 (en) | 2013-07-30 | 2016-06-08 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| BR102013033827B1 (pt) | 2013-12-27 | 2021-09-08 | Regenera - Medicina Veterinária Avançada Ltda. | Concentrado multipotente e imunocompatível de células-tronco e biofármaco e forma de dosagem que o compreendem |
| CA2962444C (en) | 2014-10-03 | 2023-09-05 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| US10531957B2 (en) | 2015-05-21 | 2020-01-14 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| AU2016342387B2 (en) | 2015-10-23 | 2021-12-09 | Rigshospitalet | Stem cell therapy based on adipose-derived stem cells |
| CN108289915A (zh) | 2015-11-24 | 2018-07-17 | 日本乐敦制药株式会社 | 包含脂肪组织来源基质细胞的肝病治疗剂及其制造方法 |
| JP6714932B2 (ja) * | 2015-12-01 | 2020-07-01 | 株式会社ＡｄｉｐｏＳｅｅｄｓ | 脊椎動物の脂肪組織由来間葉系細胞株の製造方法 |
| EP3402543B1 (en) | 2016-01-11 | 2021-09-08 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
| GB201604304D0 (en) * | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| WO2017210652A1 (en) | 2016-06-03 | 2017-12-07 | Cedars-Sinai Medical Center | Cdc-derived exosomes for treatment of ventricular tachyarrythmias |
| ES2890850T3 (es) | 2016-08-26 | 2022-01-24 | Juno Therapeutics Inc | Métodos para enumerar partículas presentes en una composición celular |
| US11541078B2 (en) | 2016-09-20 | 2023-01-03 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
| US12529033B2 (en) | 2016-11-18 | 2026-01-20 | Regents Of The University Of Minnesota | Method of isolating myogenic progenitors using CD54 |
| WO2018195210A1 (en) | 2017-04-19 | 2018-10-25 | Cedars-Sinai Medical Center | Methods and compositions for treating skeletal muscular dystrophy |
| EP3417888A1 (de) * | 2017-06-25 | 2018-12-26 | co.don AG | Verfahren zum herstellen von transplantierbarem knorpelgewebe |
| WO2019126068A1 (en) | 2017-12-20 | 2019-06-27 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
| US11622964B2 (en) | 2018-01-29 | 2023-04-11 | Institute Of Zoology, Chinese Academy Of Sciences | Method for destroying cellular mechanical homeostasis and promoting regeneration and repair of tissues and organs, and use thereof |
| CN110090300A (zh) * | 2018-01-29 | 2019-08-06 | 中国科学院动物研究所 | 一种促进组织器官的再生修复的方法及其应用 |
| US12146137B2 (en) | 2018-02-05 | 2024-11-19 | Cedars-Sinai Medical Center | Methods for therapeutic use of exosomes and Y-RNAS |
| EP3759490A1 (en) | 2018-02-28 | 2021-01-06 | Juno Therapeutics, Inc. | Methods for detecting particles present in a cell composition |
| CN114158274A (zh) * | 2019-07-22 | 2022-03-08 | 株式会社资生堂 | 真皮鞘杯细胞的鉴别方法 |
| ES2957507A1 (es) * | 2022-06-09 | 2024-01-19 | Fundacion Instituto De Investig Sanitaria Fundacion Jimenez Diaz | Tratamiento de la disfuncion de las glandulas de meibomio |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811094A (en) | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
| US6294346B1 (en) | 1991-07-08 | 2001-09-25 | Neurospheres Holdings, Ltd. | Use of multipotent neural stem cells and their progeny for the screening of drugs and other biological agents |
| CA2253724A1 (en) | 1996-04-26 | 1997-11-06 | Case Western Reserve University | Skin regeneration using mesenchymal stem cells |
| AU9127098A (en) | 1997-09-04 | 1999-03-22 | Osiris Therapeutics, Inc. | Ligands that modulate differentiation of mesenchymal stem cells |
| WO1999047163A2 (en) | 1998-03-18 | 1999-09-23 | Osiris Therapeutics, Inc. | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| US5958767A (en) | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
| JP2002537849A (ja) * | 1999-03-10 | 2002-11-12 | ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション | 脂肪由来の幹細胞および格子 |
| US20030082152A1 (en) * | 1999-03-10 | 2003-05-01 | Hedrick Marc H. | Adipose-derived stem cells and lattices |
| US20050153442A1 (en) * | 1999-03-10 | 2005-07-14 | Adam Katz | Adipose-derived stem cells and lattices |
| US7670628B2 (en) * | 1999-07-07 | 2010-03-02 | Angioblast Systems, Inc. | Mesenchymal precursor cell |
| EP1261694B1 (en) * | 2000-02-26 | 2008-01-16 | Artecel, Inc. | Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof |
| ATE384079T1 (de) * | 2002-06-14 | 2008-02-15 | Cartela Ab | Marker für stammzellen und dessen verwendung |
| BR0305721A (pt) * | 2002-07-31 | 2004-09-28 | Saint Laurent Parfums | Célula-tronco humana, população de células, processo para obtenção de células-tronco, para a produção de células diferenciadas da linhagem mesodérmica, para seleção que permite identificar agentes suscetìveis de apresentar uma atividade lipolìtica e uma atividade insulino-sensibilizante, utilização de uma célula, utilização de células-tronco, composição farmacêutica, célula humana, população celular humana multipotente |
| ES2265199B1 (es) * | 2003-06-12 | 2008-02-01 | Cellerix, S.L. | Celulas madre adultas multipotentes procedentes de condrocitos desdiferenciados y sus aplicaciones. |
| KR20060036933A (ko) * | 2003-10-07 | 2006-05-02 | 바이오마스터 인코포레이티드 | 지방-유래 전구세포의 세포 분화 |
| JP4217262B2 (ja) * | 2003-11-04 | 2009-01-28 | 株式会社バイオマスター | 脂肪組織から幹細胞を調製するための方法およびシステム |
| EP2298862B1 (en) | 2004-03-22 | 2017-08-30 | Mesoblast International Sàrl | Mesenchymal stem cells and uses therefor |
| RU2252252C1 (ru) * | 2004-04-09 | 2005-05-20 | Тепляшин Александр Сергеевич | Способ выделения мезенхимальных стволовых клеток |
| ES2313805B1 (es) | 2004-10-04 | 2009-12-23 | Cellerix, S.L. | Identificacion y aislamiento de celulas multipotentes de tejido mesenquimal no osteocondral. |
| ES2264862B8 (es) | 2004-08-25 | 2017-01-20 | Cellerix, S.L. | Biomaterial para sutura. |
| GB0814249D0 (en) * | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
-
2004
- 2004-10-04 ES ES200402355A patent/ES2313805B1/es not_active Expired - Fee Related
-
2005
- 2005-02-25 US US11/065,461 patent/US20060073124A1/en not_active Abandoned
- 2005-10-04 PT PT101830735T patent/PT2292736E/pt unknown
- 2005-10-04 DK DK10183073.5T patent/DK2292736T3/en active
- 2005-10-04 ES ES10183073.5T patent/ES2535042T3/es not_active Expired - Lifetime
- 2005-10-04 EP EP18152520.5A patent/EP3342857A1/en not_active Ceased
- 2005-10-04 WO PCT/EP2005/010811 patent/WO2006037649A1/en not_active Ceased
- 2005-10-04 JP JP2007535099A patent/JP2008515413A/ja not_active Withdrawn
- 2005-10-04 CA CA2583151A patent/CA2583151C/en not_active Expired - Lifetime
- 2005-10-04 EP EP05796904A patent/EP1812558A1/en not_active Withdrawn
- 2005-10-04 PL PL10183073T patent/PL2292736T3/pl unknown
- 2005-10-04 SI SI200531957T patent/SI2292736T1/sl unknown
- 2005-10-04 KR KR1020077010158A patent/KR20070085294A/ko not_active Ceased
- 2005-10-04 EP EP16206687.2A patent/EP3165601A1/en not_active Withdrawn
- 2005-10-04 US US11/576,573 patent/US20070248580A1/en not_active Abandoned
- 2005-10-04 EP EP10183073.5A patent/EP2292736B1/en not_active Revoked
- 2005-10-04 SG SG2013051040A patent/SG192459A1/en unknown
- 2005-10-04 CN CN200580039099.5A patent/CN101056974B/zh not_active Expired - Lifetime
- 2005-10-04 HU HUE10183073A patent/HUE025155T2/en unknown
- 2005-10-04 EP EP20140196588 patent/EP2862925A1/en not_active Withdrawn
- 2005-10-04 SG SG201000029-7A patent/SG158853A1/en unknown
- 2005-10-04 AU AU2005291353A patent/AU2005291353A1/en not_active Abandoned
-
2007
- 2007-04-10 IL IL182441A patent/IL182441A/en active IP Right Grant
-
2012
- 2012-08-24 JP JP2012185671A patent/JP5732011B2/ja not_active Expired - Lifetime
-
2015
- 2015-04-17 CY CY20151100356T patent/CY1116198T1/el unknown
- 2015-08-24 US US14/834,006 patent/US10729726B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP2292736B1 (en) | 2015-01-21 |
| JP5732011B2 (ja) | 2015-06-10 |
| DK2292736T3 (en) | 2015-04-20 |
| EP2862925A1 (en) | 2015-04-22 |
| EP2292736A3 (en) | 2011-06-15 |
| PT2292736E (pt) | 2015-04-29 |
| EP3342857A1 (en) | 2018-07-04 |
| IL182441A (en) | 2015-08-31 |
| US20170296585A1 (en) | 2017-10-19 |
| ES2535042T3 (es) | 2015-05-04 |
| EP3165601A1 (en) | 2017-05-10 |
| ES2313805B1 (es) | 2009-12-23 |
| SG192459A1 (en) | 2013-08-30 |
| CN101056974B (zh) | 2015-11-25 |
| US20060073124A1 (en) | 2006-04-06 |
| IL182441A0 (en) | 2007-07-24 |
| CN101056974A (zh) | 2007-10-17 |
| JP2013013411A (ja) | 2013-01-24 |
| CA2583151C (en) | 2015-09-15 |
| US10729726B2 (en) | 2020-08-04 |
| KR20070085294A (ko) | 2007-08-27 |
| ES2313805A1 (es) | 2009-03-01 |
| EP1812558A1 (en) | 2007-08-01 |
| PL2292736T3 (pl) | 2015-07-31 |
| JP2008515413A (ja) | 2008-05-15 |
| EP2292736A2 (en) | 2011-03-09 |
| US20070248580A1 (en) | 2007-10-25 |
| SI2292736T1 (sl) | 2015-05-29 |
| WO2006037649A1 (en) | 2006-04-13 |
| CY1116198T1 (el) | 2017-02-08 |
| CA2583151A1 (en) | 2006-04-13 |
| HUE025155T2 (en) | 2016-03-29 |
| AU2005291353A1 (en) | 2006-04-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG158853A1 (en) | Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue | |
| NZ594848A (en) | Use of adipose tissue-derived stromal stem cells in treating fistula | |
| JP2016116523A5 (es) | ||
| EP2155860A4 (en) | MULTIPOTENTIAL STEM CELLS AND THEIR USE | |
| Mafi et al. | Adult mesenchymal stem cells and cell surface characterization-a systematic review of the literature | |
| JP2008546397A5 (es) | ||
| MX2019003936A (es) | Metodo para aislar celulas madre mesenquimales a partir de membrana amniotica de cordon umbilical utilizando un medio de cultivo celular. | |
| Bochev et al. | Mesenchymal stem cells from human bone marrow or adipose tissue differently modulate mitogen‐stimulated B‐cell immunoglobulin production in vitro | |
| Wada et al. | Immunomodulatory effects of stem cells | |
| Kögler et al. | Comparative generation and characterization of pluripotent unrestricted somatic stem cells with mesenchymal stem cells from human cord blood | |
| Liu et al. | Mesenchymal stem cells: biology and clinical potential in type 1 diabetes therapy | |
| Margossian et al. | Mesenchymal stem cells derived from Wharton's jelly: comparative phenotype analysis between tissue and in vitro expansion | |
| CO6251330A2 (es) | Tratamiento de enfermedades y transtornos utilizando celulas formadoras de colonias de autorenovacion cultivadas y expandidas in vitro | |
| WO2007146106A3 (en) | Procurement, isolation and cryopreservation of maternal placental cells | |
| IL150789A0 (en) | Multipotent neural stem cells from peripheral tissues and uses thereof | |
| WO2006133052A3 (en) | A cellular therapy for ocular degeneration | |
| EP2048228B8 (en) | Human liver progenitors | |
| NZ712789A (en) | Placental stem cell populations | |
| SG179432A1 (en) | Procurement, isolation and cryopreservation of endometrial/menstrual cells | |
| WO2005116192A3 (en) | Genetically engineered cells for therapeutic applications | |
| GB2462569A (en) | Primate stem cells produced by somatic cell nuclear transfer | |
| Campioni et al. | Loss of Thy-1 (CD90) antigen expression on mesenchymal stromal cells from hematologic malignancies is induced by in vitro angiogenic stimuli and is associated with peculiar functional and phenotypic characteristics | |
| RU2015139970A (ru) | Популяция стволовых клеток шейки матки человека и ее применение | |
| WO2012008733A3 (ko) | 1기 태반조직 유래 줄기세포 및 이를 함유하는 세포치료제 | |
| EP2964755B1 (en) | Menstrual stems cells for the efficient support and expansion of cd34+ cd133+ hematopoietic stem cells in vitro |