RU2018136229A - Гербициды - Google Patents
Гербициды Download PDFInfo
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- RU2018136229A RU2018136229A RU2018136229A RU2018136229A RU2018136229A RU 2018136229 A RU2018136229 A RU 2018136229A RU 2018136229 A RU2018136229 A RU 2018136229A RU 2018136229 A RU2018136229 A RU 2018136229A RU 2018136229 A RU2018136229 A RU 2018136229A
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- Prior art keywords
- alkyl
- compound
- formula
- hydrogen
- alkoxyc
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- 239000004009 herbicide Substances 0.000 title claims 4
- 150000001875 compounds Chemical class 0.000 claims 13
- 229910052739 hydrogen Inorganic materials 0.000 claims 9
- 239000001257 hydrogen Substances 0.000 claims 9
- 125000004093 cyano group Chemical group *C#N 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 230000002363 herbicidal effect Effects 0.000 claims 6
- 125000005842 heteroatom Chemical group 0.000 claims 6
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 5
- 229910052736 halogen Inorganic materials 0.000 claims 5
- 150000002367 halogens Chemical class 0.000 claims 5
- 125000001072 heteroaryl group Chemical group 0.000 claims 5
- 150000002431 hydrogen Chemical class 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 125000004122 cyclic group Chemical group 0.000 claims 4
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims 3
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 3
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 3
- 241000196324 Embryophyta Species 0.000 claims 3
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 2
- 125000001188 haloalkyl group Chemical group 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000000575 pesticide Substances 0.000 claims 2
- -1 phenoxy, pyridinyl Chemical group 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 1
- 150000001204 N-oxides Chemical class 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 239000000729 antidote Substances 0.000 claims 1
- 125000004104 aryloxy group Chemical group 0.000 claims 1
- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 125000005553 heteroaryloxy group Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000000714 pyrimidinyl group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims 1
- 125000000335 thiazolyl group Chemical group 0.000 claims 1
- 125000001544 thienyl group Chemical group 0.000 claims 1
- 125000004001 thioalkyl group Chemical group 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/32—Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N2300/00—Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Claims (41)
1. Соединение формулы (I)
или его соль или N-оксид, где
X1 представляет собой N или CR1;
R1 выбран из группы, состоящей из водорода, галогена, циано, С1-С6алкила, С3-С6циклоалкила, С2-С6алкенила, С2-С6алкинила, C1-С6алкокси, -С(О)ОС1-С6алкила, -S(O)pC1-С6алкила, NR6R7, C1-С6галогеналкокси и С1-С6галогеналкила;
R2 выбран из группы, состоящей из галогена, циано, нитро, C1-С6алкила, С1-С6галогеналкила, С2-С6алкенила, С2-С6алкинила, С3-С6циклоалкила, -С(O)ОС1-С6алкила, -S(O)р(С1-С6алкил), C1-С6алкокси и C1-С6галогеналкокси;
R3 представляет собой -C(O)R9;
R4 выбран из группы, состоящей из водорода, C1-С6алкила, С1-С6галогеналкила, С3-С6алкенила, С3-С6алкинила, СrалкоксиCsалкила, -СrалкоксиСsгалогеналкила, СrалкоксиСsтиоалкила, -C(O)R9 и -(CRaRb)qR5;
каждый Ra независимо представляет собой водород или C1-С2алкил;
каждый Rb независимо представляет собой водород или C1-С2алкил;
Rc представляет собой водород или С1-С4алкил;
R5 представляет собой -С(O)ОС1-С6алкил, -С3-С6циклоалкил, циано, -NR6R7, -C(O)NRaRb, -S(O)p(R11)n, -арил или -гетероарил, при этом указанные арил и гетероарил необязательно замещены 1-3 независимыми R8;
R6 и R7 независимо выбраны из группы, состоящей из водорода и С1-С6алкила;
каждый R8 независимо выбран из группы, состоящей из галогена, С1-С6алкила и С1-С6алкокси-, C1-С6галогеналкила, C1-С6галогеналкокси-, циано и S(O)Р(С1-C6алкил);
каждый R9 независимо выбран из группы, состоящей из водорода, C1-С6алкила, СrалкоксиCsалкила, C1-С6галогеналкила,
СrалкоксиCsгалогеналкила, С2-С6алкенила, С2-С6алкинила и -(CRaRb)qR10;
или R4 и R9 вместе с атомами, к которым они присоединены, образуют 5-7-членную кольцевую систему, содержащую 1-3 гетероатома, при этом по меньшей мере один гетероатом представляет собой N, и любой дополнительный гетероатом независимо выбран из S, О и N;
R10 представляет собой -C(O)ORc, -OC(O)Rc, -С3-С6циклоалкил или -арильное, -арилокси-, -гетероарильное, -гетероарилокси- или -гетероциклильное кольцо, при этом указанное кольцо необязательно замещено 1-3 независимыми R8;
каждый n независимо равняется 0 или 1;
p равняется 0, 1 или 2;
каждый q независимо равняется 0, 1, 2, 3, 4, 5 или 6;
r равняется 1, 2, 3, 4 или 5;
s равняется 1, 2, 3, 4 или 5, и сумма r+s равна 6 или меньше; и
R11 представляет собой C1-С6алкил.
2. Соединение формулы (I) по п. 1, где X1 представляет собой N.
3. Соединение формулы (I) по п. 1, где X1 представляет собой CR1, и R1 представляет собой галоген или циано.
4. Соединение формулы (I) по любому из предыдущих пунктов, где R2 представляет собой галоген, циано, C1-С6алкил или C1-С6галогеналкил.
5. Соединение формулы (I) по любому из предыдущих пунктов, где в R3 R9 представляет собой C1-С6алкил, C1-С3галогеналкил, C1-С3алкоксиС1-С3алкил или -(CRaRb)qR10.
6. Соединение формулы (I) по п. 5, где R10 представляет собой -C(O)ORc, -OC(O)Rc, циклопропил, циклобутил, циклопентил, циклогексил или кольцевую систему, выбранную из фенила, фенокси, пиридинила, пиримидинила, тиазолила и тиофенила, при этом указанная кольцевая система необязательно замещена 1-3 независимыми R8.
7. Соединение формулы (I) по любому из предыдущих пунктов, где R4 выбран из группы, состоящей из водорода, С1-С4алкила, С3-С6алкенила, СrалкоксиCsалкила, СrалкилтиоCsалкила, С3-С6алкинила, С1-С3галогеналкила, СrалкоксиCsгалогеналкила, -C(O)R9 и -(CRaRb)qR5.
8. Соединение формулы (I) по п. 7, где R4 представляет собой -C(O)R9, и указанный R9 представляет собой C1-С3алкил, С2-С4алкенил или -(CRaRb)qR10.
9. Соединение формулы (I) по п. 7, где R4 представляет собой -(CRaRb)qR5, и при этом в R4
q равняется 1, 2 или 3;
Ra и Rb независимо представляют собой водород, метил или этил; и
R5 представляет собой -C(O)NRaRb, -NR6R7, циано, -С3-С6циклоалкил, -арил или -гетероарил, при этом указанные арил и гетероарил необязательно замещены 1-3 независимыми R8.
10. Соединение формулы (I) по любому из пп. 1-4, где R4 и R9 вместе с атомами, к которым они присоединены, образуют 5-7-членную кольцевую систему, содержащую 1-3 гетероатома, при этом по меньшей мере один гетероатом представляет собой N, и любой дополнительный гетероатом независимо выбран из S, О и N.
11. Гербицидная композиция, содержащая гербицидно эффективное количество соединения формулы (I) по любому из предыдущих пунктов и приемлемое с точки зрения сельского хозяйства вспомогательное средство для составления.
12. Гербицидная композиция по п. 11, дополнительно содержащая по меньшей мере один дополнительный пестицид.
13. Гербицидная композиция по п. 12, где дополнительный пестицид представляет собой гербицид или антидот гербицида.
14. Способ контроля сорняков в месте произрастания, предусматривающий применение к месту произрастания достаточного для контроля сорняков количества соединения по любому из пп. 1-10 или достаточного для контроля сорняков количества композиции по любому из пп. 11-14.
15. Применение соединения формулы (I) по любому из пп. 1-10 в качестве гербицида.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1604970.2A GB201604970D0 (en) | 2016-03-23 | 2016-03-23 | Improvements in or relating to organic compounds |
| GB1604970.2 | 2016-03-23 | ||
| PCT/EP2017/056291 WO2017162524A1 (en) | 2016-03-23 | 2017-03-16 | Herbicides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2018136229A true RU2018136229A (ru) | 2020-04-23 |
| RU2018136229A3 RU2018136229A3 (ru) | 2020-04-30 |
| RU2762575C2 RU2762575C2 (ru) | 2021-12-21 |
Family
ID=55968797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018136229A RU2762575C2 (ru) | 2016-03-23 | 2017-03-16 | Гербициды |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US11230538B2 (ru) |
| EP (2) | EP3433245B1 (ru) |
| JP (1) | JP7171437B2 (ru) |
| KR (1) | KR102423205B1 (ru) |
| CN (1) | CN108884069B (ru) |
| AR (1) | AR107953A1 (ru) |
| AU (1) | AU2017239002B2 (ru) |
| BR (2) | BR122022000691B1 (ru) |
| CA (1) | CA3016207A1 (ru) |
| DK (1) | DK3433245T3 (ru) |
| ES (1) | ES2921649T3 (ru) |
| GB (1) | GB201604970D0 (ru) |
| HU (1) | HUE059462T2 (ru) |
| MY (1) | MY197968A (ru) |
| PL (1) | PL3433245T3 (ru) |
| RS (1) | RS63363B1 (ru) |
| RU (1) | RU2762575C2 (ru) |
| UA (1) | UA124061C2 (ru) |
| UY (1) | UY37162A (ru) |
| WO (1) | WO2017162524A1 (ru) |
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| GB201604970D0 (en) * | 2016-03-23 | 2016-05-04 | Syngenta Participations Ag | Improvements in or relating to organic compounds |
| BR112018069397B1 (pt) * | 2016-03-23 | 2022-08-23 | Syngenta Participations Ag | Compostos herbicidas e composição herbicida compreendendo os referidos compostos |
| CN110446709B (zh) | 2017-01-23 | 2023-09-12 | 锐新医药公司 | 作为变构shp2抑制剂的二环化合物 |
| GB201715413D0 (en) * | 2017-09-22 | 2017-11-08 | Syngenta Participations Ag | Improvements in or relating to organic compounds |
| GB201715323D0 (en) * | 2017-09-22 | 2017-11-08 | Syngenta Participations Ag | Improvements in or relating to organic compounds |
| EP3694848A1 (en) * | 2017-10-12 | 2020-08-19 | Revolution Medicines, Inc. | Pyridine, pyrazine, and triazine compounds as allosteric shp2 inhibitors |
| CA3199238A1 (en) | 2020-10-23 | 2022-04-28 | Vertellus Holdings Llc | Methods of making nicotinic acid derivatives |
| KR102889668B1 (ko) * | 2020-11-03 | 2025-11-24 | 주식회사 엘지화학 | 작물보호제용 신규 화합물 |
| KR102889677B1 (ko) * | 2020-11-03 | 2025-11-21 | 주식회사 엘지화학 | 작물보호제용 신규 화합물 |
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| BR112018069397B1 (pt) | 2016-03-23 | 2022-08-23 | Syngenta Participations Ag | Compostos herbicidas e composição herbicida compreendendo os referidos compostos |
| GB201604970D0 (en) * | 2016-03-23 | 2016-05-04 | Syngenta Participations Ag | Improvements in or relating to organic compounds |
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| UA124061C2 (uk) | 2021-07-14 |
| PL3433245T3 (pl) | 2022-08-01 |
| KR20180128004A (ko) | 2018-11-30 |
| US11230538B2 (en) | 2022-01-25 |
| BR112018069394B1 (pt) | 2022-08-02 |
| JP7171437B2 (ja) | 2022-11-15 |
| JP2019514848A (ja) | 2019-06-06 |
| GB201604970D0 (en) | 2016-05-04 |
| US20190330179A1 (en) | 2019-10-31 |
| KR102423205B1 (ko) | 2022-07-19 |
| ZA201805795B (en) | 2019-06-26 |
| AU2017239002B2 (en) | 2021-07-29 |
| BR112018069394A2 (pt) | 2019-01-22 |
| EP3433245A1 (en) | 2019-01-30 |
| AU2017239002A1 (en) | 2018-09-13 |
| WO2017162524A1 (en) | 2017-09-28 |
| CN108884069B (zh) | 2021-04-27 |
| UY37162A (es) | 2017-10-31 |
| EP3433245B1 (en) | 2022-04-27 |
| RS63363B1 (sr) | 2022-07-29 |
| US20210130319A1 (en) | 2021-05-06 |
| BR122022000691B1 (pt) | 2023-02-23 |
| RU2018136229A3 (ru) | 2020-04-30 |
| HUE059462T2 (hu) | 2022-11-28 |
| CN108884069A (zh) | 2018-11-23 |
| AR107953A1 (es) | 2018-07-04 |
| CA3016207A1 (en) | 2017-09-28 |
| DK3433245T3 (da) | 2022-07-11 |
| EP3868749A1 (en) | 2021-08-25 |
| MY197968A (en) | 2023-07-25 |
| ES2921649T3 (es) | 2022-08-30 |
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