PT72825A - Process for the preparation of an injectable oxytetracycline composition - Google Patents

Process for the preparation of an injectable oxytetracycline composition

Info

Publication number: PT72825A
Authority: PT; Portugal
Prior art keywords: magnesium; preparation; oxytetracycline; injectable; oxytetracycline composition
Prior art date: 1980-04-10

Application number

PT72825A

Other languages

English (en)

Other versions

PT72825B (en

Original Assignee

Diamond Shamrock Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-04-10

Filing date

1981-04-09

Publication date

1981-05-01

1981-04-09 Application filed by Diamond Shamrock Corp filed Critical Diamond Shamrock Corp

1981-05-01 Publication of PT72825A publication Critical patent/PT72825A/pt

1983-01-10 Publication of PT72825B publication Critical patent/PT72825B/pt

Links

239000004100 Oxytetracycline Substances 0.000 title abstract 2
229960000625 oxytetracycline Drugs 0.000 title abstract 2
235000019366 oxytetracycline Nutrition 0.000 title abstract 2
IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 title abstract 2
IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 title 1
TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 abstract 4
OWFJMIVZYSDULZ-PXOLEDIWSA-N (4s,4ar,5s,5ar,6s,12ar)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]4(O)C(=O)C3=C(O)C2=C1O OWFJMIVZYSDULZ-PXOLEDIWSA-N 0.000 abstract 2
229910001629 magnesium chloride Inorganic materials 0.000 abstract 2
230000003115 biocidal effect Effects 0.000 abstract 1
229940074076 glycerol formal Drugs 0.000 abstract 1
239000007972 injectable composition Substances 0.000 abstract 1
UEGPKNKPLBYCNK-UHFFFAOYSA-L magnesium acetate Chemical compound [Mg+2].CC([O-])=O.CC([O-])=O UEGPKNKPLBYCNK-UHFFFAOYSA-L 0.000 abstract 1
239000011654 magnesium acetate Substances 0.000 abstract 1
229940069446 magnesium acetate Drugs 0.000 abstract 1
235000011285 magnesium acetate Nutrition 0.000 abstract 1
ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 abstract 1
239000001095 magnesium carbonate Substances 0.000 abstract 1
229910000021 magnesium carbonate Inorganic materials 0.000 abstract 1
150000002681 magnesium compounds Chemical class 0.000 abstract 1
VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 abstract 1
239000000347 magnesium hydroxide Substances 0.000 abstract 1
229910001862 magnesium hydroxide Inorganic materials 0.000 abstract 1
239000000395 magnesium oxide Substances 0.000 abstract 1
CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 abstract 1
AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Inorganic Chemistry (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Switches With Compound Operations (AREA)
Switch Cases, Indication, And Locking (AREA)
Massaging Devices (AREA)

PT72825A 1980-04-10 1981-04-09 Process for the preparation of an injectable oxytetracycline composition PT72825B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US13914780A	1980-04-10	1980-04-10

Publications (2)

Publication Number	Publication Date
PT72825A true PT72825A (en)	1981-05-01
PT72825B PT72825B (en)	1983-01-10

Family

ID=22485318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT72825A PT72825B (en)	1980-04-10	1981-04-09	Process for the preparation of an injectable oxytetracycline composition

Country Status (8)

Country	Link
EP (1)	EP0038013B1 (pt)
AT (1)	ATE14191T1 (pt)
CA (1)	CA1163197A (pt)
DE (1)	DE3171299D1 (pt)
DK (1)	DK161281A (pt)
ES (1)	ES8302459A1 (pt)
GR (1)	GR75193B (pt)
PT (1)	PT72825B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6110905A (en) *	1994-07-09	2000-08-29	Norbrook Laboratories Limited	Long-acting oxytetracycline composition
GB9413873D0 (en) *	1994-07-09	1994-08-31	Norbrook Lab Ltd	Long-acting oxytetracycline composition
US6310053B1 (en)	1995-07-05	2001-10-30	Norbrook Laboratories Limited	Long-acting oxytetracycline composition
RU2178698C1 (ru) *	2000-11-28	2002-01-27	Закрытое Акционерное Общество "Нита-Фарм"	Способ получения композиции магниевого комплекса окситетрациклина пролонгированного действия
CA2980527A1 (en)	2015-03-23	2016-09-29	BioPharmX, Inc.	Pharmaceutical tetracycline composition for dermatological use
CN111035614B (zh) *	2019-12-20	2024-02-02	北京喜禽药业有限公司	一种高含量土霉素注射液及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3004894A (en) *	1959-04-07	1961-10-17	Upjohn Co	Therapeutic composition comprising tetracycline and a dioxolane
NL141086B (nl) *	1969-03-13	1974-02-15	Diamond Shamrock Corp	Werkwijze voor het bereiden van een voor parenterale toediening geschikt oxytetracyclinepreparaat.
DE2001604C2 (de) *	1970-01-15	1983-04-14	Pfizer Gmbh, 7500 Karlsruhe	Verwendung von Polyäthylenglykol zur Herstellung von Oxytetracyclinlösungen zur parenteralen, peroralen und lokalen Anwendung
GB1508601A (en) *	1974-01-19	1978-04-26	Norbrook Labor Ltd	Oxytetracycline solution
US4018889A (en) *	1976-01-02	1977-04-19	Pfizer Inc.	Oxytetracycline compositions

1981
- 1981-03-25 CA CA000373832A patent/CA1163197A/en not_active Expired
- 1981-04-07 EP EP81102618A patent/EP0038013B1/en not_active Expired
- 1981-04-07 DE DE8181102618T patent/DE3171299D1/de not_active Expired
- 1981-04-07 AT AT81102618T patent/ATE14191T1/de active
- 1981-04-08 GR GR64619A patent/GR75193B/el unknown
- 1981-04-09 DK DK161281A patent/DK161281A/da not_active IP Right Cessation
- 1981-04-09 PT PT72825A patent/PT72825B/pt unknown
- 1981-04-09 ES ES501218A patent/ES8302459A1/es not_active Expired

Also Published As

Publication number	Publication date
ES501218A0 (es)	1983-01-16
DK161281A (da)	1981-10-11
EP0038013A2 (en)	1981-10-21
PT72825B (en)	1983-01-10
EP0038013B1 (en)	1985-07-10
DE3171299D1 (en)	1985-08-14
ATE14191T1 (de)	1985-07-15
EP0038013A3 (en)	1982-09-22
ES8302459A1 (es)	1983-01-16
CA1163197A (en)	1984-03-06
GR75193B (pt)	1984-07-13

Publication	Publication Date	Title
HK20782A (en)	1982-05-21	Antibiotic-containing composition
JPS53138446A (en)	1978-12-02	Resin composition
PT72825B (en)	1983-01-10	Process for the preparation of an injectable oxytetracycline composition
JPS53129242A (en)	1978-11-11	Chlorine-containing resin composition
JPS5243847A (en)	1977-04-06	Stabilized synthetic resin compositions
ES430344A1 (es)	1976-09-16	Procedimiento para la preparacion de hormigon inyectable impermeable al agua de alta resistencia inicial.
ES417838A1 (es)	1976-06-16	Un metodo de preparacion de granulos que contienen copoli- meros.
JPS5212256A (en)	1977-01-29	Halogen-containing resin compositions
AU474240B2 (en)	1976-07-15	Acid dyeable composition
JPS53141386A (en)	1978-12-09	Radically-curable composition
GB1532524A (en)	1978-11-15	Method of lowering the potassium oxide content of wood fly ash
JPS5225776A (en)	1977-02-25	Preparation of 2,4-disubstituted 6-membered cyclic ethers
JPS5269950A (en)	1977-06-10	Polyolefin compositions with improved now-fogging and antistatic prope rties
GB1374360A (en)	1974-11-20	Transesterification of quinoxaline-2-carboxylic acid esters
JPS5282895A (en)	1977-07-11	Fire-resistant mixture
JPS5226547A (en)	1977-02-28	Method for storing silicone-grafted polyolefin molding composition
GB1457796A (en)	1976-12-08	Metabolite a-27106 and process for its preparation and use
JPS53102332A (en)	1978-09-06	High solid urethane-paint composition
JPS5240561A (en)	1977-03-29	Novel hydrocarbon resin compositions
JPS5228544A (en)	1977-03-03	Gasket compositions based on polyvinyl chloride
JPS546039A (en)	1979-01-17	Additive for polyolefin and composition
JPS5269457A (en)	1977-06-09	Flame-retarded acrylonitrile-butadiene styrene copolymer compositions
JPS51111311A (en)	1976-10-01	Cassettes tape recorder
JPS5249260A (en)	1977-04-20	Stabilized halogen-containing resin compositions
JPS5432457A (en)	1979-03-09	Preparation of 2-alkyl-3-hydroxycyclo-pentylacetic acid esters and perfume composition containing the same