JP2018162228A - Skin external preparation or cosmetic composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a skin external preparation or a cosmetic composition having an excellent effect of sustaining a cooling sensation. SOLUTION: The following components (A) and (B); (A) contain a monoglyceride (B) cooling sensation agent for a fatty acid having 6 to 12 carbon atoms, and the content mass ratio of the components (A) and (B) ( A) / (B) is an external preparation for skin or a cosmetic composition having a value of 0.4 to 3. [Selection diagram] None

Description

  The present invention relates to an external preparation for skin or a cosmetic composition, and more particularly, to an external preparation for skin or a cosmetic composition excellent in the effect of sustaining cooling feeling.

  In the external preparation for skin or cosmetic, a cooling sensation agent is blended for the purpose of giving a refreshing feeling to the skin and scalp. For example, cooling agents such as menthol are used in lotions, shampoos, hair tonics, and the like to suppress hot flashes on the skin after sunburn and to give a refreshing feeling after use.

  However, the cooling sensation effect of such a cooling sensation agent generally decreases in a short time and is poor in sustainability. Therefore, prescription studies have been conducted for the purpose of improving the sustainability of the cooling sensation imparting effect. For example, Patent Document 1 describes that a cooling sensation effect and its sustainability can be enhanced by using a cooling sensation agent and a cationic surfactant in combination. In Patent Document 2, a surfactant combined with a cooling sensation agent and a specific polyhydric alcohol has been studied. When a nonionic surfactant is used, a cooling sensation is not exhibited, whereas a cationic surfactant is used. It has been shown that the use of an agent enhances the cooling effect and improves its sustainability.

  On the other hand, monoglycerides of fatty acids such as glyceryl caprylate have been conventionally used as nonionic surfactants and antibacterial agents, and for example, disclosed to be used as biofilm inhibitors formed by microorganisms. (Patent Document 3). However, until now, no action has been reported on the cooling sensation agent.

JP 2002-114649 A JP2013-136532A JP 2013-245187 A

  This invention makes it a subject to provide the skin external preparation or cosmetic composition which is excellent in the continuous effect of a cool feeling.

  As a result of diligent research to solve the above-mentioned problems, the present inventors combined the cooling sensation agent with a fatty acid monoglyceride at a specific ratio, so that the decrease in cooling sensation with time after application was suppressed. It has been found that the sustainability of the sensation effect is improved, and the present invention has been completed.

That is, the present invention includes the following components (A) and (B):
(A) Monoglyceride of a fatty acid having 6 to 12 carbon atoms (B) Skin containing a cooling sensate and having a mass ratio (A) / (B) of components (A) and (B) of 0.4 to 3 It is an external preparation or a cosmetic composition.

  The external preparation for skin or cosmetic composition of the present invention can impart a cooling sensation and maintain the effect for a long time.

  The skin external preparation or cosmetic composition of the present invention comprises (A) a monoglyceride of a fatty acid having 6 to 12 carbon atoms and (B) a cooling sensate as essential components.

  Component (A) A monoglyceride of a fatty acid having 6 to 12 carbon atoms is a monoester of glycerin and a fatty acid. The constituent fatty acid is a saturated or unsaturated fatty acid having 6 to 12 carbon atoms, and examples thereof include caproic acid, enanthic acid, caprylic acid, pelargonic acid, capric acid, undecyl acid, lauric acid and the like. Specific examples of the component (A) include, for example, glyceryl caproate, glyceryl caprylate, glyceryl caprate, glyceryl undecylenate, glyceryl laurate, and the like, and one or more of these can be used. Among these, from the viewpoint of the cooling sensation sustaining effect, a fatty acid having 8 to 11 carbon atoms as a constituent fatty acid is more preferable.

  As the component (B) cooling agent, 1-menthol, dl-camphor, menthyl lactate, monomenthyl succinate, menthone glycerol acetal, 3-l-menthoxypropane-1,2-diol, menthose glycerol ether, spiranthol, mint Examples thereof include oil, peppermint oil, thymol, menthyl acetate, isopulegol, cineol, borneol, thymol, other derivatives and analogs, and one or more of these can be used. Of these, 1-menthol, dl-camphor, and menthyl lactate are preferable, and l-menthol is particularly preferable from the viewpoint of a cooling sensation sustaining effect.

  The content of the component (A) in the external preparation for skin or cosmetic composition of the present invention is not particularly limited, but is 0.0001 to 3% by mass (hereinafter referred to as “%”) from the viewpoint of cooling effect and the like. Is more preferable, 0.001 to 2% is more preferable, and 0.01 to 1.5% is still more preferable. Further, the content of the component (B) is not particularly limited, but is preferably 0.0001 to 2%, more preferably 0.0005 to 1%, and still more preferably 0.001 to 0.00. 5%. The mass ratio (A) / (B) of the component (A) and the component (B) is 0.4-3. When (A) / (B) is smaller than 0.4, and when it exceeds 3, the cooling effect is not excellent. Furthermore, from the viewpoint of the cooling sensation sustaining effect, (A) / (B) is more preferably 0.4 to 1.8, further preferably 0.5 to 1.5, and particularly preferably 0.8 to 1.2. preferable.

  It is preferable that the skin external preparation or cosmetic composition of the present invention further contains a component (C) thickener from the viewpoint of cooling effect and preparation stability. Although it does not restrict | limit especially as a thickener, Synthetic polymers, such as a carbomer, acrylates / alkyl acrylate (C10-30) crosspolymer, polyvinyl alcohol, acrylic acid / alkyl methacrylate copolymer, polyacrylic acid, polyacrylamide, etc. And natural polymers such as xanthan gum, carrageenan, guar gum, locust bean gum, celluloses, agar, agarose, alkaligenes-producing polysaccharide, etc., and one or more of these can be used. Among these, carbomers, acrylates / alkyl acrylate (C10-30) crosspolymers, alkaline-genes-producing polysaccharides, and xanthan gum are preferable from the viewpoint of a cooling sensation effect, and carbomers, acrylates / alkyl acrylate (C10-30) crosspolymers are particularly preferable. Is preferred.

  The content of component (C) in the external preparation for skin or cosmetic composition of the present invention is not particularly limited, but is preferably 0.001 to 3%, more preferably 0.005 to 2 from the viewpoint of a cooling sensation sustained effect and the like. %, More preferably 0.01 to 1.5%.

  The skin external preparation or cosmetic composition of the present invention preferably further contains a component (D), an aqueous component, from the viewpoint of cooling effect and preparation stability. As the aqueous component, any component that is soluble in water may be used. Besides water, for example, monohydric alcohol such as ethanol, propylene glycol, 1,3-butylene glycol, dipropylene glycol, polyethylene glycol, glycerin. And polyhydric alcohols such as diglycerin and polyglycerin, and plant extracts such as aloe vera, lavender and rose. Among these, water, ethanol, and polyhydric alcohol are preferable. Among the polyhydric alcohols, 1,3-butylene glycol, dipropylene glycol, glycerin and propylene glycol are preferable, and 1,3-butylene glycol and dipropylene glycol are more preferable. The content of water in the external preparation for skin or cosmetic composition is preferably 20 to 90%, more preferably 30 to 85%, and still more preferably 40 to 80%. The content of the polyhydric alcohol is preferably 1 to 50%, more preferably 3 to 40%, and further preferably 5 to 30%. The ethanol content is preferably 1 to 60%, more preferably 1 to 50%, and further preferably 1 to 40%.

  The external preparation for skin or cosmetic composition of the present invention can appropriately contain, in addition to the above-mentioned components, components usually used for external preparations for skin or cosmetics as long as they do not interfere with the effects of the present invention. Examples of such optional components include oily components, powders, surfactants, aqueous components, ultraviolet absorbers, antioxidants, cosmetic components, humectants, and fragrances.

  Oily components include hydrocarbons, fats and oils, waxes, hardened oils, esters, regardless of properties such as solid oils, animal oils, vegetable oils, synthetic oils, semi-solid oils, liquid oils, volatile oils, etc. Examples thereof include oils, fatty acids, silicone oils, fluorine-based oils, lanolin derivatives, and oily gelling agents. Specifically, hydrocarbons such as liquid paraffin, squalane, petrolatum, polyethylene wax, ethylene / propylene copolymer, paraffin wax, montan wax, polyisobutylene, polybutene, ceresin wax, ozokerite wax, owl, olive oil, castor oil Oils such as mink oil, macadamian nut oil, beeswax, gay wax, carnauba wax, waxes such as candelilla wax, jojoba oil, glyceryl trioctanoate, glyceryl tribehenate, cetyl 2-ethylhexanoate, isopropyl myristate , Isopropyl palmitate, octyldodecyl myristate, pentaerythrityl tetraisostearate, pentaerythrityl rosinate, neopentyl glycol dioctanoate, cholesterol fat Esters such as esters, phytosterol fatty acid esters, triglycerides, diisostearyl malate, tridecyl trimellate, fatty acids such as stearic acid, lauric acid, myristic acid, behenic acid, isostearic acid, oleic acid, dimethylpolysiloxane, methylphenyl Polysiloxane, decamethylcyclopentasiloxane, octamethylcyclotetrasiloxane, trimethylsiloxysilicic acid, high polymerization degree methylphenyl polysiloxane, cross-linked polyether modified methylpolysiloxane, oleyl modified organopolysiloxane, behenyl modified organopolysiloxane, high Degree of polymerization: Silicones such as dimethylpolysiloxane, alkoxy-modified organopolysiloxane, fluorine-modified organopolysiloxane, perfluorodecane, Fluorine oils such as fluorooctane and perfluoropolyether, lanolin, lanolin acetate, lanolin derivatives such as lanolin fatty acid isopropyl, lanolin alcohol, sucrose fatty acid ester, dextrin fatty acid ester, starch fatty acid ester, aluminum isostearate, 12-hydroxystearic acid Examples thereof include oily gelling agents such as acids, and one or more of them can be used.

  As the powder, if it is a powder used as a powder generally used for external preparations for skin or cosmetics, a spherical shape, a plate shape, a needle-like shape, a fumed shape, a fine particle, a particle size such as a pigment class, It is not particularly limited by the particle structure such as porous or non-porous, for example, inorganic powders, glitter powders, organic powders, pigment powders, metal powders, composite powders, etc. Can be used. More specifically, white inorganic pigments such as titanium oxide, zinc oxide, cerium oxide and barium sulfate, iron oxide, carbon black, titanium / titanium oxide sintered product, chromium oxide, chromium hydroxide, bitumen, ultramarine blue, etc. Colored inorganic pigments, talc, muscovite, phlogopite, saucite, biotite, synthetic mica, sericite, synthetic sericite, kaolin, silicon carbide, bentonite, smectite, silicic anhydride, aluminum oxide, oxidation White body powders such as magnesium, zirconium oxide, antimony oxide, diatomaceous earth, aluminum silicate, magnesium aluminum silicate, calcium silicate, barium silicate, magnesium silicate, calcium carbonate, magnesium carbonate, hydroxyapatite, boron nitride , Bismuth oxychloride, fish scale foil, polyethylene terephthalate Glitter powder such as polyester, aluminum, epoxy laminated powder, polyethylene terephthalate / polyolefin laminated film powder, polyethylene terephthalate / polymethyl methacrylate laminated film powder, polyamide resin, polyethylene resin, polyacrylic resin, polyester resin, Fluorine resin, cellulose resin, polystyrene resin, copolymer resin such as styrene-acrylic copolymer resin, organic polymer resin powder such as polypropylene resin and urethane resin, organic low molecular weight such as zinc stearate and N-acyl lysine Organic powder, natural powder such as silk powder, cellulose powder, organic pigment powder such as fiber such as rayon and nylon, or metal powder such as aluminum powder, gold powder, silver powder, fine particle titanium oxide coated mica titanium, fine particle Zinc oxide coated mica Chita , Composite powders of barium sulfate-coated mica titanium, titanium oxide-containing silicon dioxide, zinc oxide-containing silicon dioxide, and the like. These powders can be used alone or in combination of two or more thereof. May be used.

  As the surfactant, any surfactant that is generally used for external preparations for skin or cosmetics can be used. Nonionic surfactant, anionic surfactant, cationic surfactant, amphoteric Surfactant etc. are mentioned. For example, glycerin fatty acid ester other than component (A), polyglycerin fatty acid ester, propylene glycol fatty acid ester, sorbitan fatty acid ester, sorbitol fatty acid ester, sucrose fatty acid ester and the like and alkylene glycol adducts thereof, polyoxyalkylene alkyl co-modification Nonionic surfactants such as silicone and polyether-modified silicone, fatty acids such as stearic acid and lauric acid and salts thereof, anionic surfactants such as polyoxyethylene alkyl ether sulfate and polyoxyethylene alkyl ether phosphate , Alkylamine salts, polyamine and alkanolamine fatty acid derivatives, cationic surfactants such as alkyl quaternary ammonium salts, amino acid type, sulfate ester type, sulfonic acid type, phosphoric acid ester Le-type, amphoteric surfactants such as lecithin.

  Examples of the ultraviolet absorber include benzophenone series, PABA series, cinnamic acid series, salicylic acid series, 4-tert-butyl-4'-methoxydibenzoylmethane, and oxybenzone. Examples of antioxidants include α-tocopherol and ascorbic acid, examples of cosmetic ingredients include vitamins, anti-inflammatory agents, herbal medicines, and examples of preservatives include paraoxybenzoic acid esters, phenoxyethanol, and 1,2-pentadiol. It is done.

  The external preparation for skin or cosmetic composition of the present invention can be prepared by mixing the above components (A) and (B) and optional components used as necessary according to a conventional method. The dosage form of the external preparation for skin or cosmetic composition of the present invention is not particularly limited, and may be aqueous, solubilized, oil-in-water, water-in-oil, or the like. In the case of an aqueous, solubilized or oil-in-water dosage form, from the viewpoint of formulation stability, the content ratio (A) / (B) of the components (A) and (B) is 0.4. It is preferable to set it to -1.8, More preferably, it is 0.5-1.5, More preferably, it is 0.8-1.2. Various properties such as liquid, gel, paste, cream, and solid can be taken as properties. The product forms include skin lotions, emulsions, beauty essences, facial cleansing foams, facial cleansing creams, sunscreens, hand creams, makeup bases, foundations, and other skin cosmetic compositions, shampoos, rinses, hair conditioners, hair mists, hair It can be set as a cosmetic composition for hair such as cream, hair essence and hair wax.

  Since the skin external preparation or cosmetic composition of the present invention thus obtained has an excellent cooling effect, it can be used as a skin external preparation or cosmetic composition for imparting a cool feeling.

  EXAMPLES Hereinafter, although an Example etc. are given and this invention is demonstrated in detail, this invention is not restrict | limited at all by these.

Examples 1-11
A lotion (solubilized type) having the formulation shown in Table 1 below was prepared according to the following production method. For each lotion, the cooling effect was evaluated by the following method. The results are also shown in Table 1.

(Production method)
A: Components (1) to (13) are mixed uniformly.
B: Components (14) to (19) are mixed uniformly.
C: A was added to B and mixed uniformly to obtain a skin lotion.

(Method for evaluating the effect of cooling sensation)
A use test was conducted by 15 specialist panels. 3 ml of each sample was placed on the inner side of the upper arm, and 10 minutes later, the feeling of cooling was evaluated by sensory evaluation. The determination was made according to the following criteria based on the number of people who felt a feeling of cooling continuously.
<Criteria>
◎: Nine or more people who felt a cold sensation ○: Seven to eight people who felt a chill sensation △: Three or more people who felt a cold sensation Less than ×: Less than 2 people feel the cold feeling

Comparative Examples 1-11
A lotion having the formulation shown in Table 2 below was prepared in the same manner as in Examples 1 to 11, and the cooling effect was evaluated. The results are also shown in Table 2.

  As shown in Tables 1 and 2, the lotions of the examples in which the cooling sensation agent (A) and the fatty acid monoglyceride (B) were used in combination at a predetermined ratio still had a cooling sensation even after 10 minutes had passed since application. Was maintained. On the other hand, (A) / (B) of about 0.3 or 4 (Comparative Examples 4 and 5), or other nonionic surfactants, cationic surfactants or oils instead of glyceryl caprylate In comparison with the cooling sensation agent alone (Comparative Example 2), almost no improvement in the cooling sensation sustaining effect was observed.

Test example 1
Stability test:
About the lotion of Examples 1, 8-9 and Comparative Examples 4 and 5, the stability test was done with the following method. The results are shown in Table 3.

(Stability evaluation method)
Each sample was placed in a transparent glass container, sealed, and stored in a thermostatic bath (5 ° C.) for 1 month, and then the transmittance was measured to evaluate the non-uniformity of the composition (the degree of poor stability over time). A spectrophotometer (measurement wavelength: 700 nm, spectrophotometer GeneQuant 100 & 1300 manufactured by GE Healthcare Japan, Inc.) was used as a measuring instrument. A disposable cell (material: PMMA, product number: BRA-759081D, manufactured by BrandTech) was used, and the measurement temperature was 25 ° C.

  The lotions of Examples 1 and 8 to 9 maintained high transparency even after storage at low temperatures and showed good stability as compared with Comparative Examples 4 and 5.

<Example 12: Lotion>
(Ingredient) (%)
1.1,3-butylene glycol 10
2. Glycerin 8
3. Ethanol 20
4). l-Menthol 0.05
5. Glyceryl caprylate 0.05
6). Xanthan gum 0.1
7). Hyaluronic acid Na 0.01
8). Hydrolyzed collagen 0.01
9. Citric acid 0.1
10. Sodium lactate 0.1
11. Fragrance 0.05
12 Purified water remaining

(Production method)
A: Components (1) to (5) are mixed uniformly.
B: Components (6) to (12) were added to A and mixed uniformly to obtain a lotion.

  The lotion of Example 12 had good stability and high cooling effect.

<Example 13: Shampoo>
(Ingredient) (%)
1. 1. Purified water remaining amount Cocoyl Methyl Taurine Na 3.9
3. Cocamidopropyl betaine 3.9
4). Laureth sulfate Na 3.5
5. Olefin (C14-16) sulfonic acid 3.0
6). Sodium benzoate 0.5
7). Cocoamphoacetate Na 2.0
8.1,3-Butylene glycol 0.1
9. Citric acid 0.5
10. EDTA-2Na 0.1
11. Polyquaternium-10 0.5
12 Na chloride 0.5
13. l-Menthol 0.5
14 dl-Camphor 0.5
15. Glyceryl caprylate 0.5
16. Ethanol 3.0
17. Fragrance 0.5

(Production method)
A: Components (1) to (12) are mixed uniformly.
B: Components (13) to (17) are mixed uniformly.
C: B was added to A and mixed uniformly to obtain a shampoo.

  The shampoo of Example 13 had good stability and high cooling effect.

<Example 14: Aerosol type emulsion>
(Ingredient) (%)
1. Purified water remaining 2.1,3-butylene glycol 15
3. Glycerol 7.7
4). Sucrose laurate 3.5
5. EDTA-2Na 0.01
6). Cetearyl alcohol 1.0
7). Behenyl alcohol 1.0
8). Polyglyceryl oleate-10 1.2
9. Polysorbate 80 1.0
10. Squalane 1.0
11. Ethanol 0.1
12 l-Menthol 0.05
13. Glyceryl caprylate 0.05
14 Fragrance 0.3

(Production method)
A: Components (1) to (5) are uniformly heated and mixed.
B: Components (6) to (10) are mixed uniformly.
C: A and B are added and emulsified.
D: Components (11) to (14) that are uniformly mixed are added to C cooled to 40 ° C.
E: The aerosol container type | mold emulsion was obtained by filling the aerosol container and enclosing carbon dioxide gas.

  The aerosol type emulsion of Example 14 had good stability and a high cooling sensation sustaining effect.

<Example 15: Base cosmetic>
(Ingredient) (%)
1. PEG-80 hydrogenated castor oil 0.4
2. 1,3-butylene glycol 12
3. Methylparaben 0.1
4). 4. Purified water remaining amount (Sodium acrylate / sodium acryloyldimethyltaurine)
Copolymer dispersion (Note 4) 1.5
6. 2- [4- (Diethylamino) -2-hydroxybenzoyl] benzoic acid hexyl ester 4
7). Methyl polysiloxane (6 cs (25 ° C.)) 2.5
8). Decamethylcyclopentasiloxane 3
9. Triethoxycaprylylsilane (3%) coated fine particle zinc oxide 6
10. (Vinyl Dimethicone / Lauryl Dimethicone) Cross Polymer 0.5
11. Polyhydroxystearic acid 0.1
12 Ethyl hexyl methoxycinnamate 7.5
13. Ethanol 5
14 l-Menthol 0.05
15. Glyceryl caprylate 0.05
(Note 4) SIMULGEL EG (manufactured by SEPPIC)

(Production method)
A: Components (1) to (5) are uniformly heated and mixed.
B: Components (6) to (8) are heated and mixed uniformly.
C: Components (9) to (12) are subjected to dispersion treatment with a three-roll mill.
D: A and B are added and emulsified.
E: C and components (13) to (15) mixed uniformly were added to D cooled to 40 ° C. to obtain a base cosmetic.
(result)
The base cosmetic of Example 15 had good stability and high cooling sensation sustaining effect.

  Since the cosmetic composition of the present invention is excellent in the cooling sensation sustaining effect, it can be suitably used for cosmetics that impart a refreshing feeling such as lotion.

Claims (6)

The following components (A) and (B);
(A) Monoglyceride of a fatty acid having 6 to 12 carbon atoms (B) Skin containing a cooling sensate and having a mass ratio (A) / (B) of components (A) and (B) of 0.4 to 3 External preparation or cosmetic composition.   The skin external preparation or cosmetic composition according to claim 1, wherein the fatty acid constituting the component (A) has 8 to 11 carbon atoms.   The skin external preparation or cosmetic composition according to claim 1 or 2, wherein the component (B) is one or more selected from the group consisting of l-menthol, menthyl lactate and dl-camphor. Furthermore, the following components (C) and (D);
(C) Thickener (D) The skin external preparation or cosmetic composition according to any one of claims 1 to 3, comprising an aqueous component.   The skin according to claim 4, wherein component (C) is one or more selected from the group consisting of carbomers, (acrylates / alkyl acrylates (C10-30)) crosspolymers, alkaligenes-producing polysaccharides and xanthan gum. External preparation or cosmetic composition. The skin external preparation or cosmetic composition according to any one of claims 1 to 5, which is for imparting a cool feeling.