JP2007039363A - Slurry for production and external preparation for skin, containing the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a technique for improving the simple white finish of masking powder. <P>SOLUTION: This external preparation for the skins comprises (1) zinc oxide, and (2) polyglycerol-modified methylpolysiloxane. In this external preparation for the skins, the polyglycerol-modified methylpolysiloxane is preferably the methylpolysiloxane having a two-dimensional structure, and the surface of the zinc oxide is preferably coated with dimethicone and/or (dimethicone/methicone) copolymer. The external preparation for the skins is preferably produced by preliminarily highly mechanically dispersing the zinc oxide in a dispersing solvent together with the polyglycerol-modified methylpolysiloxane to obtain a slurry, and then adding the slurry to an external preparation for skins. The highly mechanical dispersion is preferably performed with a sand grinder, Eiger mill, Dino mill or Cobol mill. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a slurry suitable for production of a skin external preparation and a skin external preparation containing the slurry.

  In the field of external preparation for skin, powders such as titanium dioxide and zinc oxide are contained in base makeup cosmetics and UV protective cosmetics that use the concealing power, and are used for skin stains. It is used to cover skin troubles such as, and to protect the skin from ultraviolet rays. However, it often has a white finish that looks like a white wall, and is often unnatural and has a less human touch. One reason for this is that secondary agglomeration of titanium dioxide and zinc oxide is difficult to break down, and it is used in the form of secondary agglomeration under normal conditions of use. Conceivable. In other words, if the state of presence of these concealable powders in the external preparation for the skin can be crushed to a shape close to the primary particles, the whiteness can be suppressed and the UV protection effect and skin trouble cover effect can be achieved. It can be said that there is a possibility of playing.

  As a means for improving the dispersion state of the powder, there is a method of preparing a slurry by dispersing in advance in a fluid dispersion medium using a high mechanical force dispersion device, and blending this into a preparation system. Exist. (For example, refer to Patent Document 1) Here, the slurry means a liquid / powder mixed system exhibiting a viscous fluid characteristic classified into a slurry region. However, with regard to the concealing powder, it has not been possible to expect an improvement in dispersion until the finish of the smooth whiteness is improved even with such a manufacturing method via a slurry.

  As a method for improving the dispersion of the powder, there is a method in which the surface of the powder is previously treated with another metal oxide or silicone. (See, for example, Patent Document 2, Patent Document 3, and Patent Document 4) However, even with such a method, the improvement in dispersion until the white finish of the concealed powder is improved is improved. It was the present situation that I could not expect.

  On the other hand, polyglycerin-modified methylpolysiloxane, which is a substance having a surface-active action, is used as a raw material for cosmetics, and cosmetics containing this and powders are already known. . (See, for example, Patent Document 5, Patent Document 6, and Patent Document 7) However, there is no known skin external preparation containing 1) zinc oxide and 2) polyglycerin-modified methylpolysiloxane, and 1) zinc oxide. And 2) A slurry for producing a skin external preparation, in which polyglycerin-modified methylpolysiloxane is dispersed in a dispersion medium using a high mechanical force dispersing device, is not known at all. It has not been known at all in the cosmetics or slurries having such a configuration that the dispersibility of the concealing powder is remarkably improved and the white finish of the concealing powder is improved.

JP-A-2005-002078 JP 2003-003089 A JP 2002-212032 A Japanese Patent Application Laid-Open No. 08-104606 JP 2004-169015 A JP 10-316536 A JP 2003-183117 A

  The present invention has been made under such circumstances, and an object of the present invention is to provide a technique for improving the dispersed state of the concealing powder and improving the white finish of the concealing powder. .

In view of such circumstances, the present inventors have sought for a technique for improving the smooth white finish of the concealing powder, and as a result of intensive research efforts, 1) zinc oxide and 2) polyglycerin. The inventors have found that an external preparation for skin containing a modified methylpolysiloxane has such characteristics, and has completed the invention. That is, the present invention is as follows.
(1) A skin external preparation comprising 1) zinc oxide and 2) polyglycerin-modified methylpolysiloxane.
(2) The external preparation for skin according to (1), wherein the polyglycerin-modified methylpolysiloxane has a two-dimensional structure.
(3) The skin external preparation according to (1) or (2), wherein the surface of the zinc oxide is coated with dimethicone and / or (dimethicone / methicone) copolymer.
(4) Zinc oxide is produced in advance in a process in which zinc oxide is dispersed in a dispersion medium together with polyglycerin-modified methylpolysiloxane with high mechanical force, processed into a slurry, and then incorporated into a skin external preparation. The external preparation for skin according to any one of 1) to (3).
(5) The external preparation for skin according to (4), wherein high mechanical force dispersion in the slurry preparation is performed by a sand grinder, an Eiger mill, a dyno mill or a coball mill.
(6) The external preparation for skin according to any one of (1) to (5), which is in an emulsifier form.
(7) A slurry for producing an external preparation for skin, wherein 1) zinc oxide and 2) polyglycerin-modified methylpolysiloxane are dispersed in a dispersion medium using a high mechanical force dispersing device.
(8) The slurry according to (7), wherein the surface of the zinc oxide is coated with dimethicone and / or (dimethicone / methicone) copolymer.
(9) The slurry according to (7) or (8), wherein the high mechanical force dispersing device is a sand grinder, an Eiger mill, a dyno mill or a coball mill.

  ADVANTAGE OF THE INVENTION According to this invention, the technique of improving the dispersion state of concealment powder and improving the finish of the whiteness with which concealment powder was covered can be provided.

  The external preparation for skin of the present invention is characterized by containing zinc oxide. Zinc oxide can be used without any particular limitation as long as it is normally used in skin preparations such as cosmetics. The particle size of zinc oxide is not particularly limited, but the average particle size is preferably 10 to 50 nm, and particularly preferably 15 to 40 nm. Further, such zinc oxide can be used as it is, or can be used in a form in which the surface is treated in advance. For surface treatment, powder for conventional skin external preparations such as hydrogen methylpolysiloxane baking treatment, dimethicone coating treatment, (dimethicone / methicone) copolymer coating treatment, phospholipid coating treatment, metal soap coating treatment, acrylic resin coating treatment, etc. Surface treatment that is done by the body can be applied. A particularly preferred surface treatment is a dimethicone and / or (dimethicone / methicone) copolymer coating treatment. This is because reaggregation after dispersion can be suppressed. A suitable amount of the surface treatment is 1 to 30% by mass with respect to the total amount of the powder.

  Such zinc oxide or surface-treated zinc oxide can be used by purchasing commercially available products, or by purchasing commercially available products and treating the surfaces according to conventional methods. It can also be used after. Examples of commercially available products whose surfaces are not treated include, for example, “fine-particle zinc oxide MZ-300” (average particle size 30 to 40 nm) and “MZ-500” (average particle size) sold by Teika Co., Ltd. 20-30 nm), “MZ-700” (average particle size 10-20 nm) and the like, and those treated with methicone are “fine-particle zinc oxide MZ-300S” sold by Teika Corporation. (Average particle size 30 to 40 nm), “MZ-500S” (average particle size 20 to 30 nm), “MZ-700S” (average particle size 10 to 20 nm) and the like can be preferably exemplified. , "Fine particle zinc oxide MZ-300M" (average particle size 30 to 40 nm), "MZ-500M" (average particle size 20 to 30) sold by Teika Co., Ltd. m), and "MZ-700M" (average particle size: 10 to 20 nm) can be preferably exemplified. As examples of other surface treatments, production examples thereof are shown below.

<Production Example 1>
The coated titanium dioxide was surface treated according to the formulation shown below. That is, the prescription ingredients were kneaded well in a kneader, air-dried at 150 ° C. for 24 hours and fixed, and then pulverized with a pulverizer equipped with a 2 mm herringbone screen to give the surface-treated zinc oxide 1 Obtained.
Dimethicone 10% by mass
(Dimethicone / methicone) copolymer 5% by mass
"Fine particle titanium oxide MZ-500" 85 mass%
100% by mass of methylene chloride

  The zinc oxide thus obtained exhibits a very good dispersion state when properly dispersed. As a method of appropriately dispersing, a high mechanical force dispersing device is used together with a surfactant and a dispersion medium, and the slurry is processed into a slurry (solid fluid showing the viscodynamic characteristics of the slurry region). A preferred example of the surfactant is polyglycerin-modified methylpolysiloxane. Commercially available products of polyglycerin-modified methylpolysiloxane include two-dimensional polymer silicone KF-6104, silicone KF-6100, three-dimensional structure (crosspolymer) silicone KSG-710, silicone KSG-810, silicone KSG-820, silicone KSG-830, silicone KSG-840, etc. can be illustrated suitably. (All are manufactured by Shin-Etsu Silicone Co., Ltd.) Such surfactants are preferably blended in an amount of 1 to 10% by mass based on the total amount of the slurry. Silicone is particularly suitable as the dispersion medium, and volatile silicones such as cyclomethicone and dimethicone having a viscosity of 1 mPs or less are particularly preferred. A preferable content of the dispersion medium is 30 to 70% by mass with respect to the total amount of the slurry. 20-60 mass% is suitable for content of the zinc oxide which may be surface-treated with respect to the slurry whole quantity. As the high mechanical force dispersing device used for dispersing them, a media mill can be preferably exemplified, and for example, a sand grinder, an Eiger mill, a dyno mill or a coball mill can be particularly suitably exemplified. A particularly preferred example is a coball mill. Of course, the surfactant is excellent in powder dispersibility, and when combined with the secondary aggregation suppression effect of surface treatment, it is possible to embody an excellent dispersible skin external preparation without passing through a slurry. Also exist. Such a skin external preparation also belongs to the technical scope of the present invention. In this case, the preferable content of the polyglycerin-modified methylpolysiloxane is 0.1 to 5% by mass, more preferably 0.5 to 3% by mass, based on the total amount of the external preparation for skin.

  The skin external preparation of the present invention contains 1 to 20% by mass, more preferably 5 to 15% by mass of the coated powder which may be surface-treated in the above form. In such an amount range, it is possible to realize an ultraviolet protection effect that is inconspicuous in whiteness. In particular, when the cosmetic is incorporated in such a form, even if it is zinc oxide, the protective action against ultraviolet rays B becomes remarkable.

  In the external preparation for skin of the present invention, in addition to the above-mentioned components, optional components usually used in external preparations for skin such as cosmetics can be contained within a range not impairing the effects of the present invention. . Such optional ingredients include, for example, macadamia nut oil, avocado oil, corn oil, olive oil, rapeseed oil, sesame oil, castor oil, safflower oil, cottonseed oil, jojoba oil, coconut oil, palm oil, liquid lanolin, hydrogenated coconut oil Oil, wax, oil such as beeswax, canola wax, carnauba wax, ibotarou, lanolin, reduced lanolin, hard lanolin, jojoba wax, liquid paraffin, squalane, pristane, ozokerite, paraffin, ceresin, petrolatum , Hydrocarbons such as microcrystalline wax; higher fatty acids such as oleic acid, isostearic acid, lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, undecylenic acid; cetyl alcohol, stearyl alcohol, isostearyl Higher alcohols such as alcohol, behenyl alcohol, octyldodecanol, myristyl alcohol, cetostearyl alcohol; cetyl isooctanoate, isopropyl myristate, hexyldecyl isostearate, diisopropyl adipate, di-2-ethylhexyl sebacate, cetyl lactate, malic acid Diisostearyl, di-2-ethylhexanoic acid ethylene glycol, dicaprate neopentyl glycol, di-2-heptylundecanoic acid glycerin, tri-2-ethylhexanoic acid glycerin, tri-2-ethylhexanoic acid trimethylolpropane, tri Synthetic ester oils such as trimethylolpropane isostearate and pentane erythritol tetra-2-ethylhexanoate; dimethylpolysiloxane, methylphenylpoly Linear polysiloxanes such as oxane and diphenylpolysiloxane; cyclic polysiloxanes such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexanesiloxane; amino-modified polysiloxane, polyether-modified polysiloxane, alkyl-modified polysiloxane, Oil agents such as silicone oils such as modified polysiloxanes such as fluorine-modified polysiloxanes; Anionic surfactants such as fatty acid soap (sodium laurate, sodium palmitate, etc.), potassium lauryl sulfate, triethanolamine ether of alkyl sulfates; Cationic surfactants such as stearyltrimethylammonium, benzalkonium chloride, laurylamine oxide; imidazoline-based amphoteric surfactants (2-cocoyl-2-imida Zolinium hydroxide-1-carboxyethyloxy disodium salt, etc.), betaine surfactants (alkyl betaine, amide betaine, sulfobetaine, etc.), and amphoteric surfactants such as acylmethyltaurine; sorbitan fatty acid esters (sorbitan) Monostearate, sorbitan sesquioleate, etc.), glycerin fatty acids (glyceryl monostearate, etc.), propylene glycol fatty acid esters (propylene glycol monostearate, etc.), hardened castor oil derivatives, glycerin alkyl ethers, POE sorbitan fatty acid esters (POE sorbitan monooleate, polyoxyethylene sorbitan monostearate, etc.), POE sorbite fatty acid esters (POE-sorbitol monolaurate, etc.), POE glycerin fatty acid ester Tells (POE-glycerol monoisostearate, etc.), POE fatty acid esters (polyethylene glycol monooleate, POE distearate, etc.), POE alkyl ethers (POE2-octyldodecyl ether, etc.), POE alkyl phenyl ethers (POE nonylphenyl) Ethers, etc.), Pluronic types, POE / POP alkyl ethers (POE / POP2-decyltetradecyl ether, etc.), Tetronics, POE castor oil / hardened castor oil derivatives (POE castor oil, POE hardened castor oil, etc.), Nonionic surfactants such as sucrose fatty acid ester and alkyl glucoside; polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene Polyhydric alcohols such as recall, dipropylene glycol, diglycerin, isoprene glycol, 1,2-pentanediol, 2,4-hexanediol, 1,2-hexanediol, 1,2-octanediol; sodium pyrrolidonecarboxylate Moisturizing ingredients such as lactic acid and sodium lactate; powders such as mica, talc, kaolin, synthetic mica, calcium carbonate, magnesium carbonate, anhydrous silicic acid (silica), aluminum oxide, barium sulfate, etc. whose surface may be treated Body, the surface may be treated, bengara, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine, bitumen inorganic pigments; the surface may be treated, mica titanium, fish phosphorus foil, Pearl agents such as bismuth oxychloride; red 202, red 228, red 226 which may be raked No. 4, Yellow No. 4, Blue No. 404, Yellow No. 5, Red No. 505, Red No. 230, Red No. 223, Orange No. 201, Red No. 213, Yellow No. 204, Yellow No. 203, Blue No. 1, Green No. 201, Organic dyes such as purple 201 and red 204; organic powders such as polyethylene powder, polymethyl methacrylate, nylon powder, organopolysiloxane elastomer; paraaminobenzoic acid ultraviolet absorbers; anthranilic acid ultraviolet absorbers; Salicylic acid UV absorbers; cinnamic acid UV absorbers; benzophenone UV absorbers; sugar UV absorbers; 2- (2′-hydroxy-5′-t-octylphenyl) benzotriazole, 4-methoxy- UV absorbers such as 4′-t-butyldibenzoylmethane; lower alcohols such as ethanol and isopropanol; vitamins Vitamin Bs such as A or derivatives thereof, vitamin B6 hydrochloride, vitamin B6 tripalmitate, vitamin B6 dioctanoate, vitamin B2 or derivatives thereof, vitamin B12, vitamin B15 or derivatives thereof; α-tocopherol, β-tocopherol, γ- Preferred examples include vitamins such as tocopherol and vitamin E acetate, vitamins D, vitamin H, pantothenic acid, panthetin, pyrroloquinoline quinone and the like; and antibacterial agents such as phenoxyethanol. The skin external preparation of this invention can be manufactured by processing these according to a conventional method with an essential component. As an external preparation for skin, it can be applied without particular limitation as long as it is for external application to the skin. For example, cosmetics including quasi-drugs, external preparations for skin, and external items for skin are preferable examples. it can. Further, the preparation is not particularly limited as long as it is known for external preparations for skin, for example, a solubilizer form such as lotion, an emulsifier form such as emulsion or cream, and a dispersion dosage form such as aqueous foundation. However, application to an emulsifier form is preferable in that the effect can be expressed more reliably.

  Hereinafter, the present invention will be described in more detail with reference to examples, but it is needless to say that the present invention is not limited to such examples.

  According to the prescription shown below, the slurry 1-10 which is the slurry for skin external preparation manufacture of this invention and the slurry 11 used as a comparative example were created. Separately, a slurry 12 serving as a comparative example in which the polyglycerin-modified methyl polysiloxane in the slurry 1 was replaced with polyethylene glycol-modified methyl polysiloxane was also prepared. That is, the prescription ingredients were treated with a coball mill for 24 hours to obtain each slurry.

Powders listed in Table 1 (50-adjusted cyclomethicone amount) mass%
"Silicone KF6104" 5% by mass
Cyclomethicone 45% by mass
Cyclomethicone for adjustment Mass% listed in Table 1

  Using the slurry of Example 1, a cosmetic for UV protection, which is an external preparation for skin of the present invention, and a cosmetic of a comparative example were prepared and evaluated. The evaluation items were the protective action against ultraviolet rays B, and evaluation of whiteness, covering power and film feeling by a specialized panelist (beautician n = 1). The protective action (SPF) against ultraviolet B was determined according to a method defined by the Japan Cosmetic Industry Association. This is a value indicating how many times the minimum erythema dose can be increased. The larger this value is, the higher the protective action against ultraviolet B is. The whiteness was evaluated by setting the whiteness like a tile as a score of 5, the feeling of bare skin as a score of 1, and the score between 1 and 5 was divided into 5 parts sensuously. The cover power can determine how much skin troubles such as spots are not visible when applied to the face, as in the case where score 1 does not apply cosmetics, score 2: it becomes a little difficult to see, score 3: The score value was determined based on the criteria that the stain was covered but the presence was found, score 4: almost no stain was found, and score 5: no stain was found. Feeling of the film is evaluated as follows: score 1: feel no foreign film feeling, score 2: feel slightly, score 3: feel positive, score 4: clear foreign object feeling, score 5: feel foreign object and feel uncomfortable The score value. The results are shown in Table 2.

A Slurry described in Table 2 20% by mass
Polyethylene glycol modified silicone 2% by mass
Cyclomethicone 25% by mass
1,3-butanediol 8% by mass
Ethanol 5% by mass
40% by mass of water
(Manufacturing method)
A and B were heated to 80 ° C., and gradually added to E with stirring, emulsified, and cooled with stirring to obtain a cosmetic for UV protection.

  The cosmetic 1 was manufactured without going through the slurry. That is, according to the following prescription, a and b are heated to 80 ° C., c is dispersed with a disper, emulsified by gradually adding b to the mixture under stirring, and cooled with stirring to protect UV rays. 11 was obtained. The SPF of this product was 7.12, the score of whiteness was score 3, the covering power was score 3, and the film feeling was score 3. It was found that dispersibility and the like were improved as compared with the prior art.

"Silicone KF-6014" 1% by mass
Polyethylene glycol modified silicone 2% by mass
Cyclomethicone 34% by mass
1,3-butanediol 8% by mass
Ethanol 5% by mass
40% by mass of water
C Surface-treated zinc oxide 1 10% by mass

  The present invention can be applied to skin external preparations such as UV protection cosmetics.

Claims (9)

An external preparation for skin comprising 1) zinc oxide and 2) polyglycerin-modified methylpolysiloxane. The external preparation for skin according to claim 1, wherein the polyglycerin-modified methylpolysiloxane has a two-dimensional structure. The skin external preparation according to claim 1 or 2, wherein the surface of the zinc oxide is coated with dimethicone and / or (dimethicone / methicone) copolymer. The zinc oxide is manufactured in a step of performing high mechanical force dispersion together with polyglycerin-modified methylpolysiloxane in a dispersion medium in advance and processing it into a slurry, and then incorporating it into a skin external preparation. 3. The external preparation for skin according to any one of 3 above. The external preparation for skin according to claim 4, wherein high mechanical force dispersion in the slurry preparation is performed by a sand grinder, an Eiger mill, a dyno mill, or a coball mill. It is an emulsifier form, The skin external preparation in any one of Claims 1-5 characterized by the above-mentioned. A slurry for producing an external preparation for skin, comprising 1) zinc oxide and 2) polyglycerin-modified methylpolysiloxane dispersed in a dispersion medium using a high mechanical force dispersing device. The slurry according to claim 7, characterized in that the surface of the zinc oxide is coated with dimethicone and / or (dimethicone / methicone) copolymer. The slurry according to claim 7 or 8, wherein the high mechanical force dispersing device is a sand grinder, an Eiger mill, a dyno mill or a coball mill.