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IT1190395B - Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido - Google Patents

Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido

Info

Publication number
IT1190395B
IT1190395B IT22310/85A IT2231085A IT1190395B IT 1190395 B IT1190395 B IT 1190395B IT 22310/85 A IT22310/85 A IT 22310/85A IT 2231085 A IT2231085 A IT 2231085A IT 1190395 B IT1190395 B IT 1190395B
Authority
IT
Italy
Prior art keywords
formil
ester
removal
peptide
group
Prior art date
Application number
IT22310/85A
Other languages
English (en)
Other versions
IT8522310A0 (it
Inventor
Goffredo Antonio Bolis
Giuseppe Cantarini
Col Marco Da
Original Assignee
Lark Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lark Spa filed Critical Lark Spa
Priority to IT22310/85A priority Critical patent/IT1190395B/it
Publication of IT8522310A0 publication Critical patent/IT8522310A0/it
Priority to DE8686830247T priority patent/DE3685786T2/de
Priority to EP86830247A priority patent/EP0214941B1/en
Priority to AT86830247T priority patent/ATE77627T1/de
Priority to US06/905,476 priority patent/US4851563A/en
Priority to CA000519452A priority patent/CA1290896C/en
Application granted granted Critical
Publication of IT1190395B publication Critical patent/IT1190395B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/122—Hydrolysis with acids different from HF
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT22310/85A 1985-09-30 1985-09-30 Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido IT1190395B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT22310/85A IT1190395B (it) 1985-09-30 1985-09-30 Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido
DE8686830247T DE3685786T2 (de) 1985-09-30 1986-09-05 Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n-formylaminosaeure.
EP86830247A EP0214941B1 (en) 1985-09-30 1986-09-05 Method for the removal of the formyl group from an ester of an n-formyl peptide or n-formyl aminoacid
AT86830247T ATE77627T1 (de) 1985-09-30 1986-09-05 Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n- formylaminosaeure.
US06/905,476 US4851563A (en) 1985-09-30 1986-09-09 Method for the removal of the formyl group from an ester of an N-formyl peptide or N-formyl aminoacid
CA000519452A CA1290896C (en) 1985-09-30 1986-09-30 Method for the removal of the formyl group from an ester of an n-formyl peptide or n-formyl aminoacid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22310/85A IT1190395B (it) 1985-09-30 1985-09-30 Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido

Publications (2)

Publication Number Publication Date
IT8522310A0 IT8522310A0 (it) 1985-09-30
IT1190395B true IT1190395B (it) 1988-02-16

Family

ID=11194494

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22310/85A IT1190395B (it) 1985-09-30 1985-09-30 Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido

Country Status (6)

Country Link
US (1) US4851563A (it)
EP (1) EP0214941B1 (it)
AT (1) ATE77627T1 (it)
CA (1) CA1290896C (it)
DE (1) DE3685786T2 (it)
IT (1) IT1190395B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8701035A (nl) * 1987-05-01 1988-12-01 Stamicarbon Werkwijze voor de bereiding van aspartylfenylalaninemethylester uit n-formylaspartylfenylalaninemethylester.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5823380B2 (ja) * 1974-12-05 1983-05-14 味の素株式会社 ホルミルキノ ダツリホウ
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
IT1194795B (it) * 1981-05-13 1988-09-28 Pierrel Spa Procedimento per la eliminazione del gruppo n-formile da peptidi n-formilati e da esteri di peptidi n-formilati
IT1175926B (it) * 1984-01-13 1987-08-12 Debi Derivati Biologici Procedimento per la preparazione dell'estere metilico di alfa-l-aspartil-l-fenilalanina
IT8422177A0 (it) * 1984-08-01 1984-08-01 Farchemia Spa Procedimento per la preparazione di esteri.

Also Published As

Publication number Publication date
EP0214941A2 (en) 1987-03-18
CA1290896C (en) 1991-10-15
IT8522310A0 (it) 1985-09-30
DE3685786D1 (de) 1992-07-30
EP0214941A3 (en) 1989-02-01
ATE77627T1 (de) 1992-07-15
EP0214941B1 (en) 1992-06-24
DE3685786T2 (de) 1993-01-21
US4851563A (en) 1989-07-25

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