IT1178911B - OSMOTIC DEVICE HAVING TWO THERMODYNAMIC ACTIVITIES FOR THE CONTROLLED SPEED DELIVERY OF A SUBSTANCE, PARTICULARLY A DRUG TO THE ENVIRONMENT TO WHICH IT IS INTENDED - Google Patents
OSMOTIC DEVICE HAVING TWO THERMODYNAMIC ACTIVITIES FOR THE CONTROLLED SPEED DELIVERY OF A SUBSTANCE, PARTICULARLY A DRUG TO THE ENVIRONMENT TO WHICH IT IS INTENDEDInfo
- Publication number
- IT1178911B IT1178911B IT8467283A IT6728384A IT1178911B IT 1178911 B IT1178911 B IT 1178911B IT 8467283 A IT8467283 A IT 8467283A IT 6728384 A IT6728384 A IT 6728384A IT 1178911 B IT1178911 B IT 1178911B
- Authority
- IT
- Italy
- Prior art keywords
- drug
- substance
- environment
- intended
- controlled speed
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000003204 osmotic effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- External Artificial Organs (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49376083A | 1983-05-11 | 1983-05-11 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8467283A0 IT8467283A0 (en) | 1984-03-23 |
| IT8467283A1 IT8467283A1 (en) | 1985-09-23 |
| IT1178911B true IT1178911B (en) | 1987-09-16 |
Family
ID=23961585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8467283A IT1178911B (en) | 1983-05-11 | 1984-03-23 | OSMOTIC DEVICE HAVING TWO THERMODYNAMIC ACTIVITIES FOR THE CONTROLLED SPEED DELIVERY OF A SUBSTANCE, PARTICULARLY A DRUG TO THE ENVIRONMENT TO WHICH IT IS INTENDED |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS6041609A (en) |
| AT (1) | AT397180B (en) |
| AU (1) | AU566110B2 (en) |
| BE (1) | BE898819A (en) |
| CA (1) | CA1222950A (en) |
| CH (1) | CH669329A5 (en) |
| DE (1) | DE3417113A1 (en) |
| DK (1) | DK163910C (en) |
| ES (1) | ES532018A0 (en) |
| FR (1) | FR2545721B1 (en) |
| GB (1) | GB2140687B (en) |
| IE (1) | IE56515B1 (en) |
| IL (1) | IL71727A (en) |
| IT (1) | IT1178911B (en) |
| MX (1) | MX163518B (en) |
| NL (1) | NL192250C (en) |
| NO (1) | NO170834C (en) |
| NZ (1) | NZ206600A (en) |
| SE (1) | SE455918B (en) |
| ZA (1) | ZA842422B (en) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH075457B2 (en) * | 1983-08-16 | 1995-01-25 | ザ ウエルカム フアウンデ−シヨン リミテツド | Pharmaceutical composition allowing the release of the active ingredient in a controlled manner |
| US4600773A (en) * | 1983-12-01 | 1986-07-15 | Eli Lilly And Company | Crystalline cephalexin hydrochloride monohydrate |
| US4624847A (en) * | 1985-04-22 | 1986-11-25 | Alza Corporation | Drug delivery device for programmed delivery of beneficial drug |
| US4963141A (en) * | 1985-08-16 | 1990-10-16 | Alza Corporation | Dispensing system for administering beneficial agent formulation to ruminants |
| ES8800043A1 (en) * | 1985-08-16 | 1987-10-16 | Alza Corp | Osmotic dispenser |
| US4704118A (en) * | 1985-08-16 | 1987-11-03 | Alza Corporation | Ruminant dispensing device with thermo-activated memory |
| US4723957A (en) * | 1986-02-07 | 1988-02-09 | Alza Corp. | System for delivering drug with enhanced bioacceptability |
| US4716496A (en) * | 1986-05-09 | 1987-12-29 | Eaton Corporation | Panel-mounted control station housing |
| US4814181A (en) * | 1987-09-03 | 1989-03-21 | Alza Corporation | Dosage form comprising fast agent delivery followed by slow agent delivery |
| US4816263A (en) * | 1987-10-02 | 1989-03-28 | Alza Corporation | Dosage form for treating cardiovascular diseases comprising isradipine |
| DE3871343D1 (en) * | 1987-11-25 | 1992-06-25 | American Cyanamid Co | SYSTEM FOR THE DELAYED (CONTROLLED) RELEASE OF SUBSTITUTED DIHYDROPYRIDINE CALCIUMANTAGONISTS. |
| US4837111A (en) * | 1988-03-21 | 1989-06-06 | Alza Corporation | Dosage form for dispensing drug for human therapy |
| US4855141A (en) * | 1988-03-25 | 1989-08-08 | Alza Corporation | Device comprising means for protecting and dispensing fluid sensitive medicament |
| US4859470A (en) * | 1988-06-02 | 1989-08-22 | Alza Corporation | Dosage form for delivering diltiazem |
| US5612059A (en) * | 1988-08-30 | 1997-03-18 | Pfizer Inc. | Use of asymmetric membranes in delivery devices |
| IL91398A (en) * | 1988-08-30 | 1994-05-30 | Pfizer | Pharmaceutical delivery device comprising active substance surrounded by asymmetric membrane |
| GR1000270B (en) * | 1988-09-30 | 1992-05-12 | Alza Corp | Dose for cardiovascular troubles therapy |
| US5030452A (en) * | 1989-01-12 | 1991-07-09 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
| IL92966A (en) * | 1989-01-12 | 1995-07-31 | Pfizer | Dispensing devices powered by hydrogel |
| US5108756A (en) * | 1989-01-12 | 1992-04-28 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
| EP0408496A3 (en) * | 1989-07-12 | 1992-07-01 | Ciba-Geigy Ag | Solid dosage form for pharmaceutical substances |
| US5000962A (en) * | 1989-08-25 | 1991-03-19 | Schering Corporation | Long acting diltiazem formulation |
| US4992277A (en) * | 1989-08-25 | 1991-02-12 | Schering Corporation | Immediate release diltiazem formulation |
| US5067960A (en) * | 1989-12-06 | 1991-11-26 | Medtronic, Inc. | Muscle fitness detection by colorimetry |
| US5190763A (en) * | 1990-05-07 | 1993-03-02 | Alza Corporation | Dosage form indicated for the management of abnormal posture, tremor and involuntary movement |
| US5081161A (en) * | 1990-06-15 | 1992-01-14 | E. I. Du Pont De Nemours And Company | Process for making shaped articles of a thermoplastic resin having a microcellular structure |
| NZ238867A (en) * | 1990-07-12 | 1993-08-26 | Alza Corp | Dosage form for delayed release comprising pharmaceutically active substance and a drug-release hindering means and a second composition which imbibes fluid, expands, and ejects the active substance from the device |
| CA2087435C (en) * | 1990-08-07 | 1998-05-05 | Scott Max Herbig | Use of interfacially-polymerized membranes in delivery devices |
| US5166145A (en) * | 1990-09-10 | 1992-11-24 | Alza Corporation | Antiemetic therapy |
| DK0550641T3 (en) * | 1990-09-28 | 1994-08-22 | Pfizer | Dispensing device containing a hydrophobic medium |
| US5208037A (en) * | 1991-04-22 | 1993-05-04 | Alza Corporation | Dosage forms comprising polymers comprising different molecular weights |
| EP0612519B1 (en) * | 1993-02-23 | 2001-04-04 | Wolfgang Dr. Werner | Use of a calcium formulation in a medicament for therapeutic application to milk cows suffering from hypocalcaemia |
| US6440457B1 (en) | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
| US6287598B1 (en) * | 1993-05-28 | 2001-09-11 | Alza Corporation | Method for providing sustained antiepileptic therapy |
| HU213407B (en) * | 1993-12-09 | 1997-06-30 | Egyt Gyogyszervegyeszeti Gyar | Process for producing tablet with diffusive-osmotic release |
| US5460826A (en) * | 1994-06-27 | 1995-10-24 | Alza Corporation | Morphine therapy |
| US5948787A (en) | 1997-02-28 | 1999-09-07 | Alza Corporation | Compositions containing opiate analgesics |
| DE19962924A1 (en) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituted oxazolidinones and their use |
| US6733783B2 (en) * | 2000-10-30 | 2004-05-11 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
| US20110104214A1 (en) | 2004-04-15 | 2011-05-05 | Purdue Pharma L.P. | Once-a-day oxycodone formulations |
| DE10129725A1 (en) | 2001-06-20 | 2003-01-02 | Bayer Ag | Combination therapy of substituted oxazolidinones |
| DE10300111A1 (en) | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Process for the preparation of 5-chloro-N - ({(5S) -2-oxo-3- [4- (3-oxo-4-morpholinyl) phenyl] -1,3-oxazolidin-5-yl} methyl ) -2-thiophenecarboxamide |
| US10213387B2 (en) | 2003-09-19 | 2019-02-26 | Sun Pharma Advanced Research Company Ltd. | Oral drug delivery system |
| KR101164881B1 (en) * | 2003-09-19 | 2012-07-23 | 썬 파마슈티컬 인더스트리스 리미티드 | Oral drug delivery system |
| US10226428B2 (en) | 2003-09-19 | 2019-03-12 | Sun Pharma Advanced Research Company Ltd. | Oral drug delivery system |
| DE10355461A1 (en) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Solid, high bioavailabilty oral formulations of N-substituted 5-chloro-2-thiophene-carboxamide derivative in hydrophilized form, useful for combating thrombo-embolic diseases |
| DE102004062475A1 (en) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Solid, orally administrable, modified release pharmaceutical dosage forms |
| EP1685841A1 (en) | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
| DE102005031577A1 (en) * | 2005-07-06 | 2007-01-11 | Bayer Healthcare Ag | Pharmaceutical dosage forms containing a combination of nifedipine and / or nisoldipine and an angiotensin II antagonist |
| DE102005045518A1 (en) | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | New 5-thienylaminocarbonylmethyl-oxazolidin-2-one derivatives, useful for treating and preventing thromboembolic disease, are selective inhibitors of coagulation factor Xa |
| DE102005047561A1 (en) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Drug delivery system, useful to treat and/or prevent e.g. thromboembolic disease, comprises 5-chloro-N-(((5S)-2-oxo-3-(4-(3-oxo-4-morpholinyl)-phenyl)-1,3-oxazolidine-5-yl)-methyl)-2-thiophene carboxamide with fast release active substance |
| PT1934208E (en) | 2005-10-04 | 2011-06-01 | Bayer Schering Pharma Ag | Novel polymorphous form of 5-chloro-n-({ (5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide |
| DE102008059206A1 (en) | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmaceutical dosage form containing nifedipine or nisoldipine and an angiotensin II antagonist and / or a diuretic |
| WO2010139111A1 (en) * | 2009-06-02 | 2010-12-09 | Dow Global Technologies Inc. | Sustained release dosage form |
| DE102011007272A1 (en) | 2011-04-13 | 2012-10-18 | Bayer Pharma Aktiengesellschaft | Branched 3-phenylpropionic acid derivatives and their use |
| MX2014013320A (en) | 2012-05-07 | 2015-08-10 | Bayer Pharma AG | Process for manufacturing a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil. |
| UY34856A (en) | 2012-07-03 | 2013-12-31 | Bayer Pharma AG | PHARMACEUTICAL PRESENTATION FORMS CONTAINING 5-CHLORO-N - ({(5S) -2-OXO-3- [4- (3-OXO-4- MORPHOLINYL) -PHENYL] -1,3-OXAZOLIDIN-5-IL} -METIL) -2-THIOFENCARBOXAMIDE |
| JP5941117B2 (en) * | 2014-10-17 | 2016-06-29 | ダウ グローバル テクノロジーズ エルエルシー | Sustained release formulation |
| US10905667B2 (en) | 2018-07-24 | 2021-02-02 | Bayer Pharma Aktiengesellschaft | Orally administrable modified-release pharmaceutical dosage form |
| KR20210035235A (en) | 2018-07-24 | 2021-03-31 | 바이엘 악티엔게젤샤프트 | Pharmaceutical dosage forms that can be administered orally and have modified release |
| CN112469398A (en) | 2018-07-24 | 2021-03-09 | 拜耳公司 | Pharmaceutical dosage form for oral administration with a sustained release effect |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL38538A (en) * | 1971-01-13 | 1974-09-10 | Alza Corp | Osmotic dispenser |
| US3977404A (en) * | 1975-09-08 | 1976-08-31 | Alza Corporation | Osmotic device having microporous reservoir |
| US4111202A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
| US4160452A (en) * | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
| US4200098A (en) * | 1978-10-23 | 1980-04-29 | Alza Corporation | Osmotic system with distribution zone for dispensing beneficial agent |
| US4265874A (en) * | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4449983A (en) * | 1982-03-22 | 1984-05-22 | Alza Corporation | Simultaneous delivery of two drugs from unit delivery device |
-
1983
- 1983-12-16 NZ NZ206600A patent/NZ206600A/en unknown
- 1983-12-19 AU AU22511/83A patent/AU566110B2/en not_active Expired
- 1983-12-22 GB GB08334189A patent/GB2140687B/en not_active Expired
-
1984
- 1984-01-05 IE IE10/84A patent/IE56515B1/en not_active IP Right Cessation
- 1984-01-24 NO NO840248A patent/NO170834C/en not_active IP Right Cessation
- 1984-02-02 BE BE0/212326A patent/BE898819A/en not_active IP Right Cessation
- 1984-02-13 JP JP59024947A patent/JPS6041609A/en active Granted
- 1984-02-24 DK DK099784A patent/DK163910C/en not_active IP Right Cessation
- 1984-02-29 MX MX200502A patent/MX163518B/en unknown
- 1984-03-15 AT AT0088084A patent/AT397180B/en not_active IP Right Cessation
- 1984-03-23 IT IT8467283A patent/IT1178911B/en active
- 1984-03-30 ZA ZA842422A patent/ZA842422B/en unknown
- 1984-04-05 FR FR8405362A patent/FR2545721B1/en not_active Expired
- 1984-04-27 ES ES532018A patent/ES532018A0/en active Granted
- 1984-05-02 IL IL71727A patent/IL71727A/en not_active IP Right Cessation
- 1984-05-08 NL NL8401470A patent/NL192250C/en not_active IP Right Cessation
- 1984-05-09 SE SE8402512A patent/SE455918B/en not_active IP Right Cessation
- 1984-05-09 DE DE3417113A patent/DE3417113A1/en active Granted
- 1984-05-10 CA CA000453998A patent/CA1222950A/en not_active Expired
- 1984-05-10 CH CH2309/84A patent/CH669329A5/de not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19980327 |