IE812732L - 3-amino steroid compounds - Google Patents
3-amino steroid compoundsInfo
- Publication number
- IE812732L IE812732L IE812732A IE273281A IE812732L IE 812732 L IE812732 L IE 812732L IE 812732 A IE812732 A IE 812732A IE 273281 A IE273281 A IE 273281A IE 812732 L IE812732 L IE 812732L
- Authority
- IE
- Ireland
- Prior art keywords
- steroid compounds
- image
- amino steroid
- amino
- gb2087894a
- Prior art date
Links
- 125000004066 1-hydroxyethyl group Chemical group [H]OC([H])([*])C([H])([H])[H] 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0027—Azides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The title compounds of formula I and their salts are, with certain exceptions, new: <IMAGE> W is H or OH; X is ethyl, 1-hydroxyethyl, or acetyl; or W + X = ethylidene; R, is H or Me; R2 and R3 are each H, alkyl or hydroxyalkyl, R3 alternatively being acyl (including alkoxycarbonyl and radicals derived from amino acids and peptides), and at least one of R2 and R3 being other than H. Preparation: from the corresponding primary amines (R2 = R3 = H) Use: treatment of autoimmune diseases. <IMAGE>
[GB2087894A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8024750A FR2494698A1 (en) | 1980-11-21 | 1980-11-21 | NOVEL SUBSTITUTED 3-AMINO STEROID DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE812732L true IE812732L (en) | 1982-05-21 |
| IE52188B1 IE52188B1 (en) | 1987-08-05 |
Family
ID=9248226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2732/81A IE52188B1 (en) | 1980-11-21 | 1981-11-20 | New 3-amino steroid compounds,their production and pharmaceutical compositions containing them |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS57116099A (en) |
| KR (1) | KR880001239B1 (en) |
| AT (1) | AT389703B (en) |
| AU (1) | AU546100B2 (en) |
| BE (1) | BE891201A (en) |
| CA (1) | CA1175415A (en) |
| CH (1) | CH651056A5 (en) |
| DE (1) | DE3146117A1 (en) |
| DK (1) | DK161093C (en) |
| ES (1) | ES507309A0 (en) |
| FI (1) | FI77871C (en) |
| FR (1) | FR2494698A1 (en) |
| GB (1) | GB2087894B (en) |
| HU (1) | HU184896B (en) |
| IE (1) | IE52188B1 (en) |
| IL (1) | IL64224A0 (en) |
| IT (1) | IT1172086B (en) |
| LU (1) | LU83781A1 (en) |
| NL (1) | NL8105260A (en) |
| PT (1) | PT74015B (en) |
| SE (1) | SE451456B (en) |
| SU (1) | SU1327789A3 (en) |
| ZA (1) | ZA817806B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9084800B2 (en) * | 2011-11-07 | 2015-07-21 | Natreon, Inc. | Indolealkylamino-withasteroid conjugates and method of use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2430467A (en) * | 1944-02-11 | 1947-11-11 | Glidden Co | 3-amino-derivatives of steroids and method of making same |
| US2781342A (en) * | 1952-05-17 | 1957-02-12 | Upjohn Co | Steroid enamines |
| FR1311761A (en) * | 1959-09-12 | 1962-12-14 | Clin Byla Ets | Amino compounds of the steroid series and method of preparing such compounds |
| DE1189074B (en) * | 1959-09-12 | 1965-03-18 | Clin Byla Ets | Process for the preparation of 3-amino compounds of the androstane or pregnane series |
| NL103735C (en) * | 1961-02-17 | |||
| US3503959A (en) * | 1962-03-30 | 1970-03-31 | Sterling Drug Inc | 3-amino steroids |
| US3196168A (en) * | 1964-02-18 | 1965-07-20 | American Home Prod | Aminoaroyl aminosteroids |
| BE647858A (en) * | 1964-05-13 | |||
| US3196169A (en) * | 1964-11-03 | 1965-07-20 | American Home Prod | Aminoacyl aminosteroids |
| BE672238A (en) * | 1965-11-12 | 1966-03-01 | ||
| BE811304R (en) * | 1973-10-24 | 1974-06-17 | PREPARATION PROCEDURE FOR (20 S) 3 BETA -N-DIMETHYLAMINO | |
| FR2463777A1 (en) * | 1979-08-17 | 1981-02-27 | Roussel Uclaf | NOVEL DERIVATIVES OF 5A-PREGNAN-20-OL, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS |
-
1980
- 1980-11-21 FR FR8024750A patent/FR2494698A1/en active Granted
-
1981
- 1981-10-09 SE SE8105995A patent/SE451456B/en not_active IP Right Cessation
- 1981-10-26 HU HU813135A patent/HU184896B/en unknown
- 1981-11-06 IL IL64224A patent/IL64224A0/en not_active IP Right Cessation
- 1981-11-11 ZA ZA817806A patent/ZA817806B/en unknown
- 1981-11-18 KR KR1019810004462A patent/KR880001239B1/en not_active Expired
- 1981-11-18 AT AT0497081A patent/AT389703B/en not_active IP Right Cessation
- 1981-11-19 FI FI813677A patent/FI77871C/en not_active IP Right Cessation
- 1981-11-20 AU AU77723/81A patent/AU546100B2/en not_active Ceased
- 1981-11-20 NL NL8105260A patent/NL8105260A/en not_active Application Discontinuation
- 1981-11-20 JP JP56185540A patent/JPS57116099A/en active Granted
- 1981-11-20 PT PT74015A patent/PT74015B/en unknown
- 1981-11-20 LU LU83781A patent/LU83781A1/en unknown
- 1981-11-20 CH CH7459/81A patent/CH651056A5/en not_active IP Right Cessation
- 1981-11-20 DE DE19813146117 patent/DE3146117A1/en not_active Ceased
- 1981-11-20 BE BE0/206612A patent/BE891201A/en not_active IP Right Cessation
- 1981-11-20 SU SU813355225A patent/SU1327789A3/en active
- 1981-11-20 DK DK514981A patent/DK161093C/en not_active IP Right Cessation
- 1981-11-20 ES ES507309A patent/ES507309A0/en active Granted
- 1981-11-20 IT IT49746/81A patent/IT1172086B/en active
- 1981-11-20 CA CA000390559A patent/CA1175415A/en not_active Expired
- 1981-11-20 IE IE2732/81A patent/IE52188B1/en unknown
- 1981-11-23 GB GB8135218A patent/GB2087894B/en not_active Expired
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