IE810992L - Benzodioxines - Google Patents
BenzodioxinesInfo
- Publication number
- IE810992L IE810992L IE810992A IE99281A IE810992L IE 810992 L IE810992 L IE 810992L IE 810992 A IE810992 A IE 810992A IE 99281 A IE99281 A IE 99281A IE 810992 L IE810992 L IE 810992L
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- benzodioxines
- dioxins
- benzo
- trifluoromethyl
- Prior art date
Links
- HPARLNRMYDSBNO-UHFFFAOYSA-N 1,4-benzodioxine Chemical class C1=CC=C2OC=COC2=C1 HPARLNRMYDSBNO-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 150000002013 dioxins Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Benzo(1,4)dioxins of the formula: (FORMULA) and pharmaceutically acceptable acid addition salts thereof, in which X represents hydrogen, alkyl (1-4C), alkoxy (1-4C) or trifluoromethyl, having antihypertensive properties.
[EP0039646A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8010223A FR2482101A1 (en) | 1980-05-07 | 1980-05-07 | 2-METHANOL A-AMINOMETHYL BENZO (1,4) DIOXINS, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC APPLICATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IE810992L true IE810992L (en) | 1981-11-07 |
Family
ID=9241732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE810992A IE810992L (en) | 1980-05-07 | 1981-05-06 | Benzodioxines |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0039646A1 (en) |
| JP (1) | JPS57500510A (en) |
| DK (1) | DK417481A (en) |
| ES (1) | ES8202811A1 (en) |
| FR (1) | FR2482101A1 (en) |
| IE (1) | IE810992L (en) |
| WO (1) | WO1981003172A1 (en) |
| ZA (1) | ZA812948B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02138181A (en) * | 1988-11-08 | 1990-05-28 | Ist Luso Farmaco Italia Spa | 2,2-di-substituted 2,3-dihydro- 1,4-benzodioxine derivative having antihypertensive activity |
| AU5522498A (en) * | 1996-12-13 | 1998-07-03 | Merck & Co., Inc. | Substituted aryl piperazines as modulators of chemokine receptor activity |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1038333A (en) * | 1963-02-13 | 1966-08-10 | Ici Ltd | Pharmaceutical compositions |
| US3910930A (en) * | 1973-01-04 | 1975-10-07 | Janssen Pharmaceutica Nv | 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones |
| DE2325633A1 (en) * | 1973-05-21 | 1974-12-12 | Boehringer Sohn Ingelheim | PIPERAZINE DERIVATIVES |
-
1980
- 1980-05-07 FR FR8010223A patent/FR2482101A1/en active Granted
-
1981
- 1981-05-04 ZA ZA00812948A patent/ZA812948B/en unknown
- 1981-05-04 JP JP56501462A patent/JPS57500510A/ja active Pending
- 1981-05-04 WO PCT/EP1981/000039 patent/WO1981003172A1/en not_active Ceased
- 1981-05-06 IE IE810992A patent/IE810992L/en unknown
- 1981-05-06 EP EP81400710A patent/EP0039646A1/en not_active Withdrawn
- 1981-05-07 ES ES502003A patent/ES8202811A1/en not_active Expired
- 1981-09-21 DK DK417481A patent/DK417481A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES502003A0 (en) | 1982-03-01 |
| FR2482101A1 (en) | 1981-11-13 |
| ES8202811A1 (en) | 1982-03-01 |
| DK417481A (en) | 1982-01-08 |
| EP0039646A1 (en) | 1981-11-11 |
| ZA812948B (en) | 1982-05-26 |
| JPS57500510A (en) | 1982-03-25 |
| WO1981003172A1 (en) | 1981-11-12 |
| FR2482101B1 (en) | 1983-05-27 |
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