HU903933D0 - Process for producing new acetilcholinesterase inhibitors - Google Patents

Process for producing new acetilcholinesterase inhibitors

Info

Publication number: HU903933D0
Authority: HU; Hungary
Prior art keywords: acetilcholinesterase; inhibitors; producing new; producing; new
Prior art date: 1989-06-22

Application number

HU903933A

Other languages

English (en)

Other versions

HU210569B (en

HUT54695A (en

Inventor

Daniel Schirlin

Jean-Noel Collard

Jean-Marie Hornsperger

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-22

Filing date

1990-06-20

Publication date

1990-11-28

1990-06-20 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1990-11-28 Publication of HU903933D0 publication Critical patent/HU903933D0/hu

1991-03-28 Publication of HUT54695A publication Critical patent/HUT54695A/hu

1995-05-29 Publication of HU210569B publication Critical patent/HU210569B/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Silicates, Zeolites, And Molecular Sieves (AREA)

HU903933A 1989-06-22 1990-06-20 Process for the production of novel acetylcholinesterase inhibitors and pharmaceutical compositions containing the same HU210569B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP89401775A EP0403713A1 (en)	1989-06-22	1989-06-22	Novel acetylcholinesterase inhibitors

Publications (3)

Publication Number	Publication Date
HU903933D0 true HU903933D0 (en)	1990-11-28
HUT54695A HUT54695A (en)	1991-03-28
HU210569B HU210569B (en)	1995-05-29

Family

ID=8202963

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU903933A HU210569B (en)	1989-06-22	1990-06-20	Process for the production of novel acetylcholinesterase inhibitors and pharmaceutical compositions containing the same

Country Status (19)

Country	Link
EP (2)	EP0403713A1 (hu)
JP (1)	JP2879951B2 (hu)
KR (1)	KR0139529B1 (hu)
CN (1)	CN1027759C (hu)
AR (1)	AR247214A1 (hu)
AT (1)	ATE119535T1 (hu)
AU (1)	AU626428B2 (hu)
CA (1)	CA2019231C (hu)
DE (1)	DE69017543T2 (hu)
DK (1)	DK0409676T3 (hu)
ES (1)	ES2072406T3 (hu)
FI (1)	FI97619C (hu)
HU (1)	HU210569B (hu)
IE (1)	IE66155B1 (hu)
IL (1)	IL94779A (hu)
NO (1)	NO178374C (hu)
NZ (1)	NZ234136A (hu)
PT (1)	PT94449B (hu)
ZA (1)	ZA904715B (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5523442A (en) *	1993-02-16	1996-06-04	Merrell Pharmaceuticals Inc.	Silylated acetylcholinesterase inhibitors
EP0611769A1 (en) *	1993-02-16	1994-08-24	Merrell Dow Pharmaceuticals Inc.	Silylated acetylcholinesterase inhibitors
EP0627400A1 (en) *	1993-06-04	1994-12-07	Merrell Dow Pharmaceuticals Inc.	Aromatic acetylcholinesterase inhibitors
US5554780A (en) *	1994-05-05	1996-09-10	Merrell Pharmaceuticals Inc.	Process for the preparation of 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives
US5486638A (en) *	1994-11-08	1996-01-23	Marion Merrell Dow Inc.	Process for the preparation of 1-halo-3-trialkysilanyl-benzene derivatives
EP0749972A1 (en) *	1995-06-21	1996-12-27	Merrell Pharmaceuticals Inc.	A process for preparing 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives
US6673784B1 (en)	1996-03-19	2004-01-06	G. D. Searle & Co.	Electrophilic ketones for the treatment of herpesvirus infections
CN1059702C (zh) *	1997-12-30	2000-12-20	中国科学院上海细胞生物学研究所	从哺乳类细胞中获得脑型乙酰胆碱酯酶的方法
US6218383B1 (en)	1998-08-07	2001-04-17	Targacept, Inc.	Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
US6084117A (en) *	1999-11-22	2000-07-04	Albemarle Corporation	Production of silated haloarenes by selective silylation of polyhaloarenes
EA202092673A3 (ru)	2010-02-09	2021-05-31	Дзе Джонс Хопкинс Юниверсити	Способы и композиции для улучшения когнитивной функции
US20140206667A1 (en)	2012-11-14	2014-07-24	Michela Gallagher	Methods and compositions for treating schizophrenia
WO2014090929A1 (en)	2012-12-13	2014-06-19	H. Lundbeck A/S	Compositions comprising vortioxetine and donepezil
JP6433482B2 (ja)	2013-03-15	2018-12-05	エージンバイオ，インコーポレイテッド	認知機能を改善するための方法および組成物
EP2968237A4 (en)	2013-03-15	2016-08-31	Univ Johns Hopkins	METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
BR112017025031B1 (pt)	2015-05-22	2023-03-21	Agenebio, Inc	Composições farmacêuticas de liberação prolongada de levetiracetam
CN112826794B (zh)	2019-11-06	2022-02-11	上海交通大学医学院	一种靶向修复神经血管病变的纳米复合物及其制备与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL25820A (en) *	1966-05-22	1971-02-25	Yissum Res Dev Co	Silicon containing beta-hydroxy alpha-phenyl carboxylic acids,their amide and ester derivatives and intermediates for their preparation
US4835099A (en) *	1986-11-20	1989-05-30	Becton, Dickinson And Company	Signal enhancement in immunoassay by modulation of enzymatic catalysis

1989
- 1989-06-22 EP EP89401775A patent/EP0403713A1/en not_active Withdrawn
1990
- 1990-06-18 ZA ZA904715A patent/ZA904715B/xx unknown
- 1990-06-18 CA CA002019231A patent/CA2019231C/en not_active Expired - Lifetime
- 1990-06-19 IL IL9477990A patent/IL94779A/en not_active IP Right Cessation
- 1990-06-19 AU AU57584/90A patent/AU626428B2/en not_active Ceased
- 1990-06-19 NZ NZ234136A patent/NZ234136A/xx unknown
- 1990-06-20 FI FI903104A patent/FI97619C/fi active IP Right Grant
- 1990-06-20 DE DE69017543T patent/DE69017543T2/de not_active Expired - Lifetime
- 1990-06-20 ES ES90401745T patent/ES2072406T3/es not_active Expired - Lifetime
- 1990-06-20 AT AT90401745T patent/ATE119535T1/de not_active IP Right Cessation
- 1990-06-20 EP EP90401745A patent/EP0409676B1/en not_active Expired - Lifetime
- 1990-06-20 AR AR90317164A patent/AR247214A1/es active
- 1990-06-20 HU HU903933A patent/HU210569B/hu not_active IP Right Cessation
- 1990-06-20 DK DK90401745.6T patent/DK0409676T3/da active
- 1990-06-21 KR KR1019900009196A patent/KR0139529B1/ko not_active Expired - Fee Related
- 1990-06-21 IE IE225290A patent/IE66155B1/en not_active IP Right Cessation
- 1990-06-21 NO NO902776A patent/NO178374C/no not_active IP Right Cessation
- 1990-06-21 PT PT94449A patent/PT94449B/pt not_active IP Right Cessation
- 1990-06-22 CN CN90103127A patent/CN1027759C/zh not_active Expired - Fee Related
- 1990-06-22 JP JP2163002A patent/JP2879951B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ZA904715B (en)	1991-04-24
JPH0338591A (ja)	1991-02-19
NZ234136A (en)	1994-04-27
CN1048389A (zh)	1991-01-09
EP0409676A1 (en)	1991-01-23
AU626428B2 (en)	1992-07-30
FI903104A0 (fi)	1990-06-20
ES2072406T3 (es)	1995-07-16
IE66155B1 (en)	1995-12-13
NO178374B (no)	1995-12-04
AR247214A1 (es)	1994-11-30
PT94449B (pt)	1997-02-28
IE902252L (en)	1990-12-22
DK0409676T3 (da)	1995-03-27
NO902776L (no)	1990-12-27
NO178374C (no)	1996-03-13
ATE119535T1 (de)	1995-03-15
NO902776D0 (no)	1990-06-21
IE902252A1 (en)	1991-01-16
KR910000757A (ko)	1991-01-30
DE69017543T2 (de)	1995-07-06
AU5758490A (en)	1991-01-03
FI97619B (fi)	1996-10-15
HU210569B (en)	1995-05-29
CA2019231A1 (en)	1990-12-22
CN1027759C (zh)	1995-03-01
DE69017543D1 (de)	1995-04-13
FI97619C (fi)	1997-01-27
IL94779A (en)	1996-09-12
EP0403713A1 (en)	1990-12-27
EP0409676B1 (en)	1995-03-08
JP2879951B2 (ja)	1999-04-05
HUT54695A (en)	1991-03-28
PT94449A (pt)	1991-02-08
KR0139529B1 (ko)	1998-07-01
CA2019231C (en)	2000-07-11

Publication	Publication Date	Title
HU904585D0 (en)	1990-12-28	Process for producing new fluorine containing peptidaze inhibitors
HU902462D0 (en)	1990-08-28	Process for producing 3-substituted-2-oxindole derivatives
HUT46707A (en)	1988-11-28	Process for producing new peptidase inhibitors
YU99590A (en)	1991-10-31	Process for obtaining cephiriaxone
HU903933D0 (en)	1990-11-28	Process for producing new acetilcholinesterase inhibitors
HUT57790A (en)	1991-12-30	Process for producing deoxyfluoronucleoside derivatives
HU902106D0 (en)	1990-07-28	Process for producing cephodisime-disodium
HU907154D0 (en)	1991-05-28	Process for producing acat inhibitors
HU907034D0 (en)	1991-05-28	Process for producing acat inhibitors
HU901814D0 (en)	1990-07-28	Process for producing inhibitors of aldose-reductase
HUT54409A (en)	1991-02-28	Process for producing new somatotropin-analogues
HU903908D0 (en)	1990-11-28	Process for producing new r(-)-3-quinuclidinole derivatives
HU904920D0 (en)	1991-01-28	Process for producing neoalkyl-triol-triesthers
HU903160D0 (en)	1990-10-28	Process for producing new compounds
HU906464D0 (en)	1991-04-29	Process for producing chloro-fluoro-propanes
HU907033D0 (en)	1991-05-28	Process for producing acat inhibitors
HU906520D0 (en)	1991-04-29	Process for producing diaza-bicycloamine derivatives
HU905944D0 (en)	1991-03-28	Process for producing new macrolidic compounds
HU907221D0 (en)	1991-05-28	Process for producing cepheme derivatives
HUT54607A (en)	1991-03-28	Process for producing chloro-carboxylic acid-chlorides
HUT54096A (en)	1991-01-28	Process for producing fluoro-phenols
HU906514D0 (en)	1991-04-29	Process for producing phenoxi-heterocyclic compounds
HUT61250A (en)	1992-12-28	Process for producing tetrathiocarbonates
EP0429077A3 (en)	1991-11-13	Process for producing inulooligosaccharides
HUT58281A (en)	1992-02-28	Process for producing 4-trans-/n-isopropyliden-amino/-cyclohexanol

Legal Events

Date	Code	Title	Description
2001-03-28	HMM4	Cancellation of final prot. due to non-payment of fee