[go: up one dir, main page]

HU903057D0 - Process for the preparation of optically active 2-aryl-alkan-carboxylic acids, especially 2-aryl-propionic acids - Google Patents

Process for the preparation of optically active 2-aryl-alkan-carboxylic acids, especially 2-aryl-propionic acids

Info

Publication number
HU903057D0
HU903057D0 HU903057A HU305790A HU903057D0 HU 903057 D0 HU903057 D0 HU 903057D0 HU 903057 A HU903057 A HU 903057A HU 305790 A HU305790 A HU 305790A HU 903057 D0 HU903057 D0 HU 903057D0
Authority
HU
Hungary
Prior art keywords
active ingredient
aryl
excipient
solution
crystalline
Prior art date
Application number
HU903057A
Other languages
English (en)
Other versions
HUT54610A (en
Inventor
Henrich H Paradies
Samir B Hanna
Bernd Schneider
Original Assignee
Puetter Medice Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Puetter Medice Chem Pharm filed Critical Puetter Medice Chem Pharm
Publication of HU903057D0 publication Critical patent/HU903057D0/hu
Publication of HUT54610A publication Critical patent/HUT54610A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Catalysts (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU903057A 1989-05-16 1990-05-16 Process for producing optically active 2-aryl-alkanoil acids, first of all 2-aryl-propionic acids HUT54610A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35226989A 1989-05-16 1989-05-16

Publications (2)

Publication Number Publication Date
HU903057D0 true HU903057D0 (en) 1990-09-28
HUT54610A HUT54610A (en) 1991-03-28

Family

ID=23384455

Family Applications (2)

Application Number Title Priority Date Filing Date
HU904479A HUT56263A (en) 1989-05-16 1990-05-16 Process for producing water-soluble pharmaceutical compositions
HU903057A HUT54610A (en) 1989-05-16 1990-05-16 Process for producing optically active 2-aryl-alkanoil acids, first of all 2-aryl-propionic acids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU904479A HUT56263A (en) 1989-05-16 1990-05-16 Process for producing water-soluble pharmaceutical compositions

Country Status (16)

Country Link
US (1) US5380927A (hu)
EP (2) EP0398288B1 (hu)
JP (2) JPH03209344A (hu)
KR (1) KR920700613A (hu)
CN (2) CN1053010A (hu)
AT (1) ATE129230T1 (hu)
AU (3) AU5509190A (hu)
CA (2) CA2016888A1 (hu)
DD (2) DD300404A5 (hu)
DE (3) DE4015794A1 (hu)
FI (1) FI902435A7 (hu)
HU (2) HUT56263A (hu)
IL (2) IL94420A0 (hu)
NO (2) NO902190L (hu)
WO (1) WO1990014073A1 (hu)
ZA (2) ZA903756B (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT59692A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alkanoic acids and aminosugars
UA34430C2 (uk) 1991-05-13 2001-03-15 Дзе Бутс Компані Плс S(-)-2-(4-ізобутилфеніл)пропіонат натрію дигідрат, придатний для лікування запалення, болю і гіпертермії, фармацевтична композиція на його основі та спосіб одержання s(-)-2-(4-ізобутилфеніл)пропіонату натрію
EP0661989B1 (en) * 1992-09-21 1997-08-06 PHARMACIA & UPJOHN COMPANY Sustained-release protein formulations
ES2100037T3 (es) * 1992-12-02 1997-06-01 Knoll Ag Proceso para preparar enantiomeros sustancialmente puros de acidos fenilpropionicos.
IT1272149B (it) * 1993-03-26 1997-06-11 Zambon Spa Composizione farmeceutiche ad attivita' analgesica
JPH08509222A (ja) * 1993-04-22 1996-10-01 ミネソタ マイニング アンド マニュファクチャリング カンパニー 経皮抗炎症性組成物
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
DK106293D0 (da) * 1993-09-22 1993-09-22 Joergen Rasmussen Kapsel til indbringning af laegemidler i kreaturmaver
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
US20060030826A1 (en) * 1996-06-04 2006-02-09 Vance Products Incorporated,d/b/a Cook Urological Incorporated Implantable medical device with anti-neoplastic drug
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
FR2878746B1 (fr) 2004-12-02 2007-02-23 Vetoquinol Sa Sa Nouvelle composition pharmaceutique utilisable dans le domaine des vaccins
EP1690528A1 (de) * 2005-02-11 2006-08-16 Abbott GmbH & Co. KG Herstellung von Dosierungsformen mit einer festen Dispersion eines mikrokristallinen Wirkstoffs
UA119247C2 (uk) 2013-09-06 2019-05-27 РОЙВЕНТ САЙЕНСИЗ ҐмбГ Спіроциклічні сполуки як інгібітори триптофангідроксилази
US9611201B2 (en) 2015-03-05 2017-04-04 Karos Pharmaceuticals, Inc. Processes for preparing (R)-1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanol and 1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanone
WO2018187717A1 (en) * 2017-04-06 2018-10-11 Sri International Continuous flow synthesis of ibuprofen
GB2568698A (en) * 2017-11-23 2019-05-29 Akl Res & Development Ltd Formulation
CN112457182A (zh) * 2020-12-16 2021-03-09 江苏慧聚药业有限公司 一种氟比洛芬杂质的制备方法
CN119492694B (zh) * 2024-11-12 2025-09-30 科顺防水科技股份有限公司 化学阻根剂手性分布的测量方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB942743A (en) * 1959-05-22 1963-11-27 Welloome Foundation Ltd Oestrogen preparations and the manufacture thereof
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
FR1591573A (hu) * 1968-05-10 1970-05-04
US3862311A (en) * 1971-04-12 1975-01-21 Ciba Geigy Corp Novel method of enhancing progestational endometrial proliferation with progesterone
US3927084A (en) * 1973-01-29 1975-12-16 Nisshin Flour Milling Co Process for the production of 2(4-alkylphenyl)propionic acid
JPS5335069B2 (hu) * 1973-01-29 1978-09-25
IT1059677B (it) * 1974-03-22 1982-06-21 Neopharmed Spa Sale di lisina ad azione terapeutica
FR2287217A1 (fr) * 1974-10-08 1976-05-07 Hommel Ag Nouveaux acides phenylalcanoiques substitues et leurs derives, ainsi que procede de leur preparation et medicaments
US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
GB1480971A (en) * 1975-04-03 1977-07-27 Prodotti Antibiotici Spa Preparation of isobutylphenyl compounds
IT1051442B (it) * 1975-05-22 1981-04-21 Ind Chimica Prodotti Francis S Procedimento per la preparazione di derivati dell acido para isobutil fenilacetico
US4209638A (en) * 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
GB1572226A (en) * 1977-11-03 1980-07-30 Hoechst Uk Ltd Pharmaceutical preparations in solid unit dosage form
JPS6072976A (ja) * 1983-09-30 1985-04-25 Sagami Chem Res Center 水素化アルミニウムリチウム系不斉還元剤
DE3563848D1 (en) * 1984-04-06 1988-08-25 Zambon Spa Process for the preparation of optically active alpha-arylalkanoic acids and intermediates thereof
JPS6112294A (ja) * 1984-06-26 1986-01-20 Kureha Chem Ind Co Ltd ２−（置換フエニル）プロピオン酸の製造方法
DE3438830A1 (de) * 1984-10-23 1986-04-30 Rentschler Arzneimittel Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung
IT1201408B (it) * 1985-03-22 1989-02-02 Montedison Spa Processo per la preparazione biotecnologica di acidi alfa-arilalcanoici otticamente attivi
GB8514489D0 (en) * 1985-06-07 1985-07-10 Shell Int Research Producing 2-arylpropionic acids
JPS632935A (ja) * 1986-06-20 1988-01-07 Sumitomo Chem Co Ltd 光学活性アルコ−ル類の製造方法
US4851444A (en) * 1987-07-10 1989-07-25 Analgesic Associates Onset-hastened/enhanced analgesia
GB8716975D0 (en) * 1987-07-17 1987-08-26 Boots Co Plc Therapeutic agents
US4962124A (en) * 1987-11-17 1990-10-09 Analgesic Associates Onset-hastened/enhanced antipyretic response
US4868214A (en) * 1987-11-17 1989-09-19 Analgesic Associates Onset-hastened/enhanced analgesia

Also Published As

Publication number Publication date
JPH03209344A (ja) 1991-09-12
EP0398288B1 (de) 1995-10-18
IL94420A0 (en) 1991-03-10
AU3987893A (en) 1993-08-19
CN1053010A (zh) 1991-07-17
DE4015781A1 (de) 1990-12-13
HUT54610A (en) 1991-03-28
CA2016888A1 (en) 1990-11-16
HUT56263A (en) 1991-08-28
DE4015794A1 (de) 1990-11-29
ZA903756B (en) 1991-02-27
DE59009781D1 (de) 1995-11-23
AU5509290A (en) 1990-11-22
EP0398288A3 (de) 1992-01-15
AU643210B2 (en) 1993-11-11
KR920700613A (ko) 1992-08-10
HU904479D0 (en) 1991-06-28
NO902190D0 (no) 1990-05-16
NO905132L (no) 1990-11-29
EP0398288A2 (de) 1990-11-22
EP0398287A1 (de) 1990-11-22
ATE129230T1 (de) 1995-11-15
AU5509190A (en) 1990-11-22
WO1990014073A1 (de) 1990-11-29
JPH03506040A (ja) 1991-12-26
ZA903759B (en) 1991-02-27
DD300404A5 (de) 1992-06-11
US5380927A (en) 1995-01-10
FI902435A0 (fi) 1990-05-16
FI902435A7 (fi) 1990-11-17
CN1050373A (zh) 1991-04-03
DD300688A5 (de) 1992-07-02
NO902190L (no) 1990-11-19
IL94419A0 (en) 1991-03-10
NO905132D0 (no) 1990-11-27
CA2016887A1 (en) 1990-11-16

Similar Documents

Publication Publication Date Title
AU643210B2 (en) Process for preparing optically active 2-aryl-alkanoic acids, in particular 2-ayrl-propionic acids
FR2679467B1 (fr) Dispersion solide d'au moins un alcool polyhydrique dans un milieu anhydre et procede de preparation.
CA2103086A1 (en) Clear Antiperspirant Gel Stick and Method for Making Same
EP0796649A4 (en) PROCESS FOR THE PREPARATION OF A POLYETHER ETHER CETONE MEMBRANE
KR100459279B1 (ko) 장쇄 ｎ-아실 산성 아미노산의 제조 방법
CA1326036C (en) Process for the production of alkali metal salts of 2-pyrrolidon-5-carboxylic acid
DE2961566D1 (en) Process for the preparation of optically active 3-substituted 2-(2',2'-dihalovinyl)-cyclopropane-1-carboxylic acids and their derivatives; 4-(2',2',2'-trihaloethyl)-cyclobutane-1-sulphonic acid salts and their preparation
IE791875L (en) Sodium amoxicillin preparations
DK571683A (da) Antihelmintiske gelsammensaetninger og en fremgangsmaade til fremstilling heraf ved omgivelsernes temperatur
DE3363093D1 (en) Acid salts of 2-piperazinopyrimidine, process for their preparation and pharmaceutical compositions containing them
ATE69804T1 (de) Verfahren zur herstellung von d- oder l-alanin hoher enantiomerenreinheit.
EP0359956A3 (de) Verfahren und Vorrichtung zur Herstellung von 1,3-Diaminopropanol-2
HU201345B (en) Process for preparing shape-proof carrier gel
JPS6452741A (en) Novel process for producing optically active 1-(p-tolyl) ethylamine
IT1239892B (it) Procedimento per preparare uno smalto per prodotti ceramici che permette di migliorare la qualita'della produzione,e smalto cosi' ottenuto

Legal Events

Date Code Title Description
DFC9 Refusal of application