GB2019393A - Process for the preparation of 2- (3-benzoylphenyl)-propionic acid - Google Patents
Process for the preparation of 2- (3-benzoylphenyl)-propionic acidInfo
- Publication number
- GB2019393A GB2019393A GB7912148A GB7912148A GB2019393A GB 2019393 A GB2019393 A GB 2019393A GB 7912148 A GB7912148 A GB 7912148A GB 7912148 A GB7912148 A GB 7912148A GB 2019393 A GB2019393 A GB 2019393A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzoylphenyl
- propionic acid
- preparation
- thallium
- iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 title abstract 3
- XWVKTOHUMPLABF-UHFFFAOYSA-N thallium(3+) Chemical class [Tl+3] XWVKTOHUMPLABF-UHFFFAOYSA-N 0.000 abstract 2
- KSQSNIADOOKZAT-UHFFFAOYSA-N 1-(3-benzoylphenyl)propan-1-one Chemical compound CCC(=O)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 KSQSNIADOOKZAT-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052901 montmorillonite Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A process for the preparation of 2 -(3-benzoylphenyl)-propionic acid comprises treating 3- propionylbenzophenone with a thallium (III) salt in a suitable solvent, thereby to produce an intermediate ester which is hydrolyzed to produce the desired 2-(3-benzoylphenyl) propionic acid. In a particular mode of carrying out the process of the invention the thallium (III) salt may be bound to a suitable carrier, such as an acidic montmorillonite earth.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| YU83578A YU39566B (en) | 1978-04-07 | 1978-04-07 | Process of preparing 2-(3-benzoyl-phenyl)-propionic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2019393A true GB2019393A (en) | 1979-10-31 |
| GB2019393B GB2019393B (en) | 1982-06-03 |
Family
ID=25551632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7912148A Expired GB2019393B (en) | 1978-04-07 | 1979-04-06 | Process for the preparation of 2-(3-benzoylphenyl)-propionic acid |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS584698B2 (en) |
| AT (1) | AT367730B (en) |
| DE (1) | DE2913770C2 (en) |
| FR (1) | FR2421865A1 (en) |
| GB (1) | GB2019393B (en) |
| PL (1) | PL114485B1 (en) |
| YU (1) | YU39566B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2163986A1 (en) * | 1999-07-13 | 2002-02-01 | Menarini Lab | Set of inflammation and pain inhibitors for e.g. cyclooxygenase activity inhibitors comprises alpha aryl propionic acids and aryl acetic acids |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8400239D0 (en) * | 1984-01-19 | 1984-01-19 | Pharmacia Ab | NEW ARYLETIC ACID DERIVATIVES |
| JPH07100678B2 (en) * | 1987-03-12 | 1995-11-01 | 日本石油化学株式会社 | Method for producing α- (3-benzoylphenyl) propionic acid |
| ES2050072B1 (en) * | 1992-07-28 | 1994-12-16 | Menarini Lab | "PROCEDURE FOR OBTAINING META- AND PARA-ACILBENZOIC ACIDS" |
-
1978
- 1978-04-07 YU YU83578A patent/YU39566B/en unknown
-
1979
- 1979-04-04 AT AT0247879A patent/AT367730B/en not_active IP Right Cessation
- 1979-04-05 DE DE19792913770 patent/DE2913770C2/en not_active Expired
- 1979-04-06 PL PL21474479A patent/PL114485B1/en unknown
- 1979-04-06 GB GB7912148A patent/GB2019393B/en not_active Expired
- 1979-04-06 FR FR7908740A patent/FR2421865A1/en not_active Withdrawn
- 1979-04-07 JP JP4156779A patent/JPS584698B2/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2163986A1 (en) * | 1999-07-13 | 2002-02-01 | Menarini Lab | Set of inflammation and pain inhibitors for e.g. cyclooxygenase activity inhibitors comprises alpha aryl propionic acids and aryl acetic acids |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2019393B (en) | 1982-06-03 |
| JPS584698B2 (en) | 1983-01-27 |
| PL214744A1 (en) | 1979-12-17 |
| PL114485B1 (en) | 1981-01-31 |
| DE2913770C2 (en) | 1983-03-10 |
| FR2421865A1 (en) | 1979-11-02 |
| AT367730B (en) | 1982-07-26 |
| YU39566B (en) | 1984-12-31 |
| JPS54157540A (en) | 1979-12-12 |
| YU83578A (en) | 1982-10-31 |
| ATA247879A (en) | 1981-12-15 |
| DE2913770A1 (en) | 1979-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |