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GB1049290A - Synthetic polypeptides - Google Patents

Synthetic polypeptides

Info

Publication number
GB1049290A
GB1049290A GB32561/62A GB3256162A GB1049290A GB 1049290 A GB1049290 A GB 1049290A GB 32561/62 A GB32561/62 A GB 32561/62A GB 3256162 A GB3256162 A GB 3256162A GB 1049290 A GB1049290 A GB 1049290A
Authority
GB
United Kingdom
Prior art keywords
lambda
polypeptide
solvent
filament
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB32561/62A
Inventor
Alan Arthur Randall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel UK PLC
Original Assignee
Courtaulds PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE636530D priority Critical patent/BE636530A/xx
Priority to NL297020D priority patent/NL297020A/xx
Application filed by Courtaulds PLC filed Critical Courtaulds PLC
Priority to GB32561/62A priority patent/GB1049290A/en
Priority to US295223A priority patent/US3331814A/en
Priority to DE19631495312 priority patent/DE1495312A1/en
Priority to FR945456A priority patent/FR1367282A/en
Priority to CH1044263A priority patent/CH431552A/en
Priority to SE9241/63A priority patent/SE303832B/xx
Priority to AT678963A priority patent/AT262517B/en
Publication of GB1049290A publication Critical patent/GB1049290A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/08—At least partially resorbable materials of animal origin, e.g. catgut, collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/06—Wet spinning methods
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/58—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products
    • D01F6/68—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyaminoacids or polypeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Materials Engineering (AREA)
  • Textile Engineering (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Analytical Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A process for making a synthetic polypeptide filament or film comprises forming a mixture of the N-carboanhydride derivatives of an lambda-imino acid and an lambda-amino acid in an inert solvent for the polypeptide, initiating the reaction of the derivatives to form the synthetic polypeptide with evolution of carbon dioxide and extruding the polypeptide dissolved in the solvent to form a filament or a film by contact with a coagulant or by evaporation of the solvent. The example describes the reaction of lambda-proline N-carboxy anhydride with g -methyl lambda-glutamate N-carboxy anhydride in the presence of ethyl acetate and methylene chloride, tri-n-butylamine being used as initiator.
GB32561/62A 1962-08-24 1962-08-24 Synthetic polypeptides Expired GB1049290A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
BE636530D BE636530A (en) 1962-08-24
NL297020D NL297020A (en) 1962-08-24
GB32561/62A GB1049290A (en) 1962-08-24 1962-08-24 Synthetic polypeptides
US295223A US3331814A (en) 1962-08-24 1963-07-15 Synthetic polypeptides of an l-imino acid and an l-amino acid
DE19631495312 DE1495312A1 (en) 1962-08-24 1963-07-25 Threads or yarns suitable for medical purposes and processes for their manufacture
FR945456A FR1367282A (en) 1962-08-24 1963-08-23 Enzyme-hydrolyzable polypeptides, their preparation and applications
CH1044263A CH431552A (en) 1962-08-24 1963-08-23 Process for the preparation of synthetic polypeptides
SE9241/63A SE303832B (en) 1962-08-24 1963-08-23
AT678963A AT262517B (en) 1962-08-24 1963-08-23 Process for the production of new polypeptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB32561/62A GB1049290A (en) 1962-08-24 1962-08-24 Synthetic polypeptides

Publications (1)

Publication Number Publication Date
GB1049290A true GB1049290A (en) 1966-11-23

Family

ID=10340564

Family Applications (1)

Application Number Title Priority Date Filing Date
GB32561/62A Expired GB1049290A (en) 1962-08-24 1962-08-24 Synthetic polypeptides

Country Status (9)

Country Link
US (1) US3331814A (en)
AT (1) AT262517B (en)
BE (1) BE636530A (en)
CH (1) CH431552A (en)
DE (1) DE1495312A1 (en)
FR (1) FR1367282A (en)
GB (1) GB1049290A (en)
NL (1) NL297020A (en)
SE (1) SE303832B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113150064A (en) * 2021-04-14 2021-07-23 中山大学 Artificial synthesis method and application of antibacterial and insect-resistant peptide

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3626948A (en) * 1968-12-23 1971-12-14 American Cyanamid Co Absorbable polyglycolic acid suture of enhanced in-vivo strength retention
US3867520A (en) * 1971-04-14 1975-02-18 Ajinomoto Kk Medicated polyamino acid film for occlusive dressing therapy
US3773737A (en) * 1971-06-09 1973-11-20 Sutures Inc Hydrolyzable polymers of amino acid and hydroxy acids
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
NL8202894A (en) * 1982-07-16 1984-02-16 Rijksuniversiteit POLYESTER FILAMENT MATERIAL.
US5110852A (en) * 1982-07-16 1992-05-05 Rijksuniversiteit Te Groningen Filament material polylactide mixtures
US4955913A (en) * 1985-03-28 1990-09-11 Robinson Walter C Surgical tie
US5101011A (en) * 1990-07-20 1992-03-31 Ajinomoto Co., Inc. Aligning agent for liquid crystals comprising poly alpha-amino acid having no optical activity
AU771188B2 (en) * 1999-03-05 2004-03-18 Shire Llc Use of protein conformation for the protection and release of chemical compounds
US7018654B2 (en) * 1999-03-05 2006-03-28 New River Pharmaceuticals Inc. Pharmaceutical composition containing an active agent in an amino acid copolymer structure
US6716452B1 (en) * 2000-08-22 2004-04-06 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US8394813B2 (en) 2000-11-14 2013-03-12 Shire Llc Active agent delivery systems and methods for protecting and administering active agents
US7169752B2 (en) * 2003-09-30 2007-01-30 New River Pharmaceuticals Inc. Compounds and compositions for prevention of overdose of oxycodone
US20060014697A1 (en) * 2001-08-22 2006-01-19 Travis Mickle Pharmaceutical compositions for prevention of overdose or abuse

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL238058A (en) * 1958-04-21
US3052655A (en) * 1958-08-01 1962-09-04 Sidney W Fox Thermal polymerization of amino acid mixtures containing aspartic acid or a thermal precursor of aspartic acid
US3076790A (en) * 1958-08-01 1963-02-05 Sidney W Fox Method of making copolymers of amino acids containing glutamic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113150064A (en) * 2021-04-14 2021-07-23 中山大学 Artificial synthesis method and application of antibacterial and insect-resistant peptide

Also Published As

Publication number Publication date
CH431552A (en) 1967-03-15
SE303832B (en) 1968-09-09
DE1495312A1 (en) 1969-03-06
NL297020A (en)
US3331814A (en) 1967-07-18
AT262517B (en) 1968-06-10
FR1367282A (en) 1964-07-17
BE636530A (en)

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