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FI970247L - Farmaseuttisia koostumuksia, jotka sisältävät kimeerisen TNF:ää sitovan proteiinin - Google Patents

Farmaseuttisia koostumuksia, jotka sisältävät kimeerisen TNF:ää sitovan proteiinin Download PDF

Info

Publication number
FI970247L
FI970247L FI970247A FI970247A FI970247L FI 970247 L FI970247 L FI 970247L FI 970247 A FI970247 A FI 970247A FI 970247 A FI970247 A FI 970247A FI 970247 L FI970247 L FI 970247L
Authority
FI
Finland
Prior art keywords
pharmaceutical compositions
binding protein
compositions containing
chimeric tnf
tnf
Prior art date
Application number
FI970247A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI970247A7 (fi
FI970247A0 (fi
Inventor
Robert Fredrich Geoffrey Booth
Werner Lesslauer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI970247L publication Critical patent/FI970247L/fi
Publication of FI970247A7 publication Critical patent/FI970247A7/fi
Publication of FI970247A0 publication Critical patent/FI970247A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI970247A 1994-07-22 1995-07-15 Farmaseuttisia koostumuksia, jotka sisältävät kimeerisen TNF:ää sitovan proteiinin FI970247A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94111455 1994-07-22
PCT/EP1995/002788 WO1996003141A1 (fr) 1994-07-22 1995-07-15 Compositions pharmaceutiques comprenant une proteine chimere liant le facteur de necrose tumorale

Publications (3)

Publication Number Publication Date
FI970247L true FI970247L (fi) 1997-01-21
FI970247A7 FI970247A7 (fi) 1997-01-21
FI970247A0 FI970247A0 (fi) 1997-01-21

Family

ID=8216138

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970247A FI970247A0 (fi) 1994-07-22 1995-07-15 Farmaseuttisia koostumuksia, jotka sisältävät kimeerisen TNF:ää sitovan proteiinin

Country Status (11)

Country Link
EP (1) EP0772449A1 (fr)
JP (1) JPH09508140A (fr)
AU (1) AU3111995A (fr)
BR (1) BR9508419A (fr)
CA (1) CA2195665A1 (fr)
CZ (1) CZ283219B6 (fr)
FI (1) FI970247A0 (fr)
HU (1) HUT76666A (fr)
NO (1) NO970264L (fr)
PL (1) PL318501A1 (fr)
WO (1) WO1996003141A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6350730B1 (en) 1994-08-17 2002-02-26 The Rockefeller University OB polypeptides and modified forms as modulators of body weight
US6429290B1 (en) 1994-08-17 2002-08-06 The Rockefeller University OB polypeptides, modified forms and derivatives
US6471956B1 (en) 1994-08-17 2002-10-29 The Rockefeller University Ob polypeptides, modified forms and compositions thereto
US20030040467A1 (en) 1998-06-15 2003-02-27 Mary Ann Pelleymounter Ig/ob fusions and uses thereof.
US6936439B2 (en) 1995-11-22 2005-08-30 Amgen Inc. OB fusion protein compositions and methods
KR20000010825A (ko) * 1996-05-08 2000-02-25 프리돌린 클라우스너, 롤란드 비. 보레르 종양괴사인자 수용체-면역 글로불린 융합 단백질을 사용한 천식의 치료방법
TW555765B (en) * 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
US7070771B1 (en) 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
AU5516898A (en) * 1996-12-12 1998-07-03 Genentech Inc. Hvem polypeptides and uses thereof
HK1040795B (en) 1998-11-27 2003-12-24 Synaptics (Uk) Limited position sensor
IL157446A0 (en) 2001-02-23 2004-03-28 Immunex Corp Immunex Corp Increased recovery of active proteins
WO2003011323A1 (fr) * 2001-07-30 2003-02-13 Genset S.A. Agonistes et antagonistes du contabix, destines au traitement de troubles metaboliques
US7786282B2 (en) 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
WO2003066165A1 (fr) 2002-02-06 2003-08-14 Ares Trading S.A. Facteur de necrose de tumeurs combine a un interferon dans le traitement de maladies demyelinisantes
JP5553963B2 (ja) 2004-10-22 2014-07-23 アムジエン・インコーポレーテツド 組換え抗体をリフォールディングする方法
US11111284B2 (en) 2014-08-21 2021-09-07 The General Hospital Corporation Tumor necrosis factor superfamily and TNF-like ligand muteins and methods of preparing

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98078A0 (en) * 1991-05-07 1992-06-21 Yeda Res & Dev Pharmaceutical compositions comprising an anticytokyne
EP1132471A3 (fr) * 1989-09-12 2001-11-28 F. Hoffmann-La Roche Ag Protéines liant le TNF
GB9015908D0 (en) * 1990-07-19 1990-09-05 Celltech Ltd Multivalent immunoglobulin
NZ256293A (en) * 1992-09-15 1997-06-24 Immunex Corp Method of treating tumour necrosis factor - mediated inflammation by use of tnf antagonist
AU682156B2 (en) * 1992-10-15 1997-09-25 Dana-Farber Cancer Institute, Inc. Treatment of insulin resistance in obesity linked type II diabetes using antagonists to TNF-alpha function

Also Published As

Publication number Publication date
CZ19397A3 (en) 1997-06-11
CA2195665A1 (fr) 1996-02-08
NO970264L (no) 1997-03-24
NO970264D0 (no) 1997-01-21
HUT76666A (en) 1997-10-28
PL318501A1 (en) 1997-06-23
FI970247A7 (fi) 1997-01-21
AU3111995A (en) 1996-02-22
JPH09508140A (ja) 1997-08-19
EP0772449A1 (fr) 1997-05-14
BR9508419A (pt) 1997-11-18
WO1996003141A1 (fr) 1996-02-08
FI970247A0 (fi) 1997-01-21
CZ283219B6 (cs) 1998-02-18

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