[go: up one dir, main page]

FI913817A7 - Nya utförningsformer av den huvudsakliga HIV-neutraliserande determinanten - Google Patents

Nya utförningsformer av den huvudsakliga HIV-neutraliserande determinanten Download PDF

Info

Publication number
FI913817A7
FI913817A7 FI913817A FI913817A FI913817A7 FI 913817 A7 FI913817 A7 FI 913817A7 FI 913817 A FI913817 A FI 913817A FI 913817 A FI913817 A FI 913817A FI 913817 A7 FI913817 A7 FI 913817A7
Authority
FI
Finland
Prior art keywords
new embodiments
major determinant
hiv neutralizing
hiv
neutralizing
Prior art date
Application number
FI913817A
Other languages
English (en)
Finnish (fi)
Other versions
FI913817L (fi
FI913817A0 (fi
Inventor
John A Lewis
Joseph P Davide
Julie Ann Waterbury
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI913817A0 publication Critical patent/FI913817A0/fi
Publication of FI913817L publication Critical patent/FI913817L/fi
Publication of FI913817A7 publication Critical patent/FI913817A7/sv

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI913817A 1990-08-13 1991-08-12 Nya utförningsformer av den huvudsakliga HIV-neutraliserande determinanten FI913817A7 (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56665490A 1990-08-13 1990-08-13
US56665690A 1990-08-13 1990-08-13
US56663890A 1990-08-13 1990-08-13

Publications (3)

Publication Number Publication Date
FI913817A0 FI913817A0 (fi) 1991-08-12
FI913817L FI913817L (fi) 1992-02-14
FI913817A7 true FI913817A7 (sv) 1992-02-14

Family

ID=27415998

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913817A FI913817A7 (sv) 1990-08-13 1991-08-12 Nya utförningsformer av den huvudsakliga HIV-neutraliserande determinanten

Country Status (11)

Country Link
EP (1) EP0471407A3 (sv)
JP (1) JPH06321808A (sv)
KR (1) KR920004422A (sv)
AU (1) AU642751B2 (sv)
CA (1) CA2048594A1 (sv)
FI (1) FI913817A7 (sv)
IE (1) IE912846A1 (sv)
IL (1) IL99077A0 (sv)
NO (1) NO913127L (sv)
NZ (1) NZ239281A (sv)
PT (1) PT98633A (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2071088A1 (en) * 1991-06-19 1992-12-20 Emilio A. Emini Conjugates of the class ii protein of the outer membrane of neisseria meningitidis and of hiv-1 related peptides, and vaccines containing same
US5556744A (en) * 1992-05-29 1996-09-17 The Trustees Of The University Of Pennsylvania Methods and compositions for diagnosing and treating certain HIV infected patients
GB2282378A (en) * 1993-09-30 1995-04-05 Merck & Co Inc Conjugates of epitopes of HIV with a protein complex from Neisseria
GB2282380A (en) * 1993-09-30 1995-04-05 Merck & Co Inc Conjugate of epitopes of HIV with a protein complex from Neisseria
FI961350L (sv) * 1994-07-25 1996-03-25 Boehringer Mannheim Gmbh Hapten-märkta peptider
GB2294047A (en) * 1994-10-14 1996-04-17 Merck & Co Inc Synthetic peptides for use as epitopes specific for HIV
FR2731225B1 (fr) * 1995-03-03 2003-10-31 Pasteur Institut Peptides de glycoproteine transmembranaire d'enveloppe et de proteine de capside du retrovirus humain du type hiv-1 et peptides presentant avec eux une parente immunologique
CA2652992C (fr) 1994-10-20 2014-10-07 Institut Pasteur Sequences nucleotidiques d'antigenes retroviraux vih-1 groupe (ou sous-groupe) o
US7090848B1 (en) * 1998-08-04 2006-08-15 Henry M. Jackson Foundation For The Advancement Of Military Medicine HIV-1 envelope protein associated with a broadly reactive neutralizing antibody response
US6911527B1 (en) 1999-01-11 2005-06-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services HIV related peptides
WO2000042068A2 (en) * 1999-01-11 2000-07-20 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hiv related peptides
US8022040B2 (en) * 2004-11-29 2011-09-20 The Regents Of The University Of California Hydroxyapatite-binding peptides for bone growth and inhibition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695624A (en) * 1984-05-10 1987-09-22 Merck & Co., Inc. Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
NZ214503A (en) * 1984-12-20 1990-02-26 Merck & Co Inc Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates
CA1339363C (en) * 1987-05-01 1997-08-26 Alan Ray Flesher Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
NL8702403A (nl) * 1987-10-09 1989-05-01 Stichting Centr Diergeneeskund Oligopeptiden en gebruik daarvan voor diagnostische en vaccinatiedoeleinden voor aids en arc.
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
AU640619B2 (en) * 1988-10-03 1993-09-02 Repligen Corporation Hiv proteins and peptides useful in the diagnosis, prophylaxis or therapy of aids
IL94558A0 (en) * 1989-06-06 1991-03-10 Merck & Co Inc Conjugate immunogen for aids and vaccine and pharmaceutical compositions containing it

Also Published As

Publication number Publication date
EP0471407A2 (en) 1992-02-19
FI913817L (fi) 1992-02-14
FI913817A0 (fi) 1991-08-12
NO913127L (no) 1992-02-14
NO913127D0 (no) 1991-08-12
IE912846A1 (en) 1992-02-26
AU8177791A (en) 1992-02-20
AU642751B2 (en) 1993-10-28
CA2048594A1 (en) 1992-02-14
JPH06321808A (ja) 1994-11-22
KR920004422A (ko) 1992-03-27
NZ239281A (en) 1993-09-27
IL99077A0 (en) 1992-07-15
EP0471407A3 (en) 1993-05-12
PT98633A (pt) 1992-06-30

Similar Documents

Publication Publication Date Title
FI914174A7 (sv) Förfarande för framställning av piperidylalkylaminer
FI963424A7 (sv) Förfarande för framställning av terapeutiskt aktiva tiofensulfonamider
FI905451A0 (fi) Vaermekaendande silikonkompositionen med foerbaettrad livstid i flytande form.
FI906208A7 (sv) Virala ämnen
FI930070A7 (fi) Hiv-inhiberande benzenacetamidderivat
BR9100276A (pt) Poco submarino
FI910624A7 (sv) Degar
NO911122D0 (no) Fremgangsmaate for fremstilling av antihyperkolesterolemiske midler.
FI913817A7 (sv) Nya utförningsformer av den huvudsakliga HIV-neutraliserande determinanten
TR24939A (tr) Triazolinonlarin istihsal edilmesi
FI930894A0 (fi) Form foer flotationsprodukter
FI930674L (fi) Terapeutiska aemnen
MX9102079A (es) Plemezcla de semduramicina
FI923486A7 (fi) Terapeutiska aemnen.
FI931071L (fi) Terapeutiska aemnen
FI913285A0 (fi) Svavelsubstituerade mevinsyraderivat.
KR920004444U (ko) 용광로 내부 관찰구
ZA916344B (en) New embodiments of the hiv principal neutralizing determinant
FI901420A7 (sv) Producering av modifierat PE40
DK0439244T3 (da) Nodulariseringsfremgangsmåde
FI923528L (fi) Terapeutiska aemnen.
KR920012095U (ko) 용광로 내부 관찰구
FI931938A7 (sv) Mellanprodukter vid framställning av 4,5-difluorantranilinsyra
FI913414A7 (sv) Förfarande för framställning av 2-hydroxi-3-halogen-5-nitropyridiner
FI906365L (fi) Borsttvaettmaskin foer slaktdjur.

Legal Events

Date Code Title Description
FD Application lapsed