[go: up one dir, main page]

EE200000146A - Monoamiini oksüdaasi inhibiitori kombinatsioon h5-HT 1B antagonisti või osalise agonistiga - Google Patents

Monoamiini oksüdaasi inhibiitori kombinatsioon h5-HT 1B antagonisti või osalise agonistiga

Info

Publication number
EE200000146A
EE200000146A EEP200000146A EEP200000146A EE200000146A EE 200000146 A EE200000146 A EE 200000146A EE P200000146 A EEP200000146 A EE P200000146A EE P200000146 A EEP200000146 A EE P200000146A EE 200000146 A EE200000146 A EE 200000146A
Authority
EE
Estonia
Prior art keywords
combination
monoamine oxidase
partial agonist
oxidase inhibitor
ht1b antagonist
Prior art date
Application number
EEP200000146A
Other languages
English (en)
Inventor
Berg Stefan
Ross Svante
Thorberg Seth-Olov
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000146A publication Critical patent/EE200000146A/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200000146A 1997-09-18 1998-09-09 Monoamiini oksüdaasi inhibiitori kombinatsioon h5-HT 1B antagonisti või osalise agonistiga EE200000146A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9703376A SE9703376D0 (sv) 1997-09-18 1997-09-18 A new combination
PCT/SE1998/001602 WO1999013878A1 (en) 1997-09-18 1998-09-09 A COMBINATION OF A MONOAMINE OXIDASE INHIBITOR AND A h5-HT1B ANTAGONIST OR PARTIAL AGONIST

Publications (1)

Publication Number Publication Date
EE200000146A true EE200000146A (et) 2001-02-15

Family

ID=20408296

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000146A EE200000146A (et) 1997-09-18 1998-09-09 Monoamiini oksüdaasi inhibiitori kombinatsioon h5-HT 1B antagonisti või osalise agonistiga

Country Status (27)

Country Link
US (1) US6159970A (et)
EP (1) EP1014986B1 (et)
JP (1) JP2001516719A (et)
KR (2) KR20010024084A (et)
CN (1) CN1278727A (et)
AR (1) AR013503A1 (et)
AT (1) ATE270889T1 (et)
AU (1) AU752719B2 (et)
BR (1) BR9812236A (et)
CA (1) CA2302204A1 (et)
DE (1) DE69825062T2 (et)
DK (1) DK1014986T3 (et)
EE (1) EE200000146A (et)
ES (1) ES2222603T3 (et)
HU (1) HUP0100621A2 (et)
ID (1) ID25789A (et)
IL (1) IL134775A0 (et)
IS (1) IS5401A (et)
MX (1) MXPA00002616A (et)
NO (1) NO20001400L (et)
PL (1) PL339368A1 (et)
PT (1) PT1014986E (et)
SE (1) SE9703376D0 (et)
SK (1) SK2832000A3 (et)
TR (1) TR200000725T2 (et)
WO (1) WO1999013878A1 (et)
ZA (1) ZA987804B (et)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957948A (en) * 1988-05-05 1990-09-18 Interface, Inc. Biocidal protective coating for heat exchanger coils
SE9601110D0 (sv) 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives
WO2002066454A1 (fr) * 2001-02-21 2002-08-29 Sankyo Company, Limited Derives de chromene
JP5080716B2 (ja) * 2001-07-20 2012-11-21 サイコジェニックス・インコーポレーテッド 注意欠陥・多動性障害の治療
US7732162B2 (en) 2003-05-05 2010-06-08 Probiodrug Ag Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
WO2007108742A1 (en) * 2006-03-17 2007-09-27 Astrazeneca Ab Novel tetralins as 5-ht6 modulators
JP5379692B2 (ja) 2006-11-09 2013-12-25 プロビオドルグ エージー 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての3−ヒドロキシ−1,5−ジヒドロ−ピロール−2−オン誘導体
EP2091948B1 (en) 2006-11-30 2012-04-18 Probiodrug AG Novel inhibitors of glutaminyl cyclase
EP2117540A1 (en) 2007-03-01 2009-11-18 Probiodrug AG New use of glutaminyl cyclase inhibitors
WO2008128985A1 (en) 2007-04-18 2008-10-30 Probiodrug Ag Thiourea derivatives as glutaminyl cyclase inhibitors
WO2011029920A1 (en) 2009-09-11 2011-03-17 Probiodrug Ag Heterocylcic derivatives as inhibitors of glutaminyl cyclase
WO2011107530A2 (en) 2010-03-03 2011-09-09 Probiodrug Ag Novel inhibitors
ES2481823T3 (es) 2010-03-10 2014-07-31 Probiodrug Ag Inhibidores heterocíclicos de glutaminil ciclasa (QC, EC 2.3.2.5)
EP2560953B1 (en) 2010-04-21 2016-01-06 Probiodrug AG Inhibitors of glutaminyl cyclase
ES2570167T3 (es) 2011-03-16 2016-05-17 Probiodrug Ag Derivados de benzimidazol como inhibidores de glutaminil ciclasa
EP3461819B1 (en) 2017-09-29 2020-05-27 Probiodrug AG Inhibitors of glutaminyl cyclase
WO2020183011A1 (en) 2019-03-14 2020-09-17 Institut Curie Htr1d inhibitors and uses thereof in the treatment of cancer
CN110179988A (zh) * 2019-07-10 2019-08-30 王大伟 五羟色胺再摄取抑制剂和单胺氧化酶抑制剂联合在制备治疗抑郁症或早泄药物中的应用
IL321485A (en) * 2022-12-14 2025-08-01 Luminous Mind Inc Treatment of psychological symptoms affecting other medical conditions (PFAOMC)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9119932D0 (en) * 1991-09-18 1991-10-30 Glaxo Group Ltd Chemical compounds
ES2162792T3 (es) * 1991-09-18 2002-01-16 Glaxo Group Ltd Derivados de benzanilida como antagonistas de 5-ht1d.
SE9601110D0 (sv) * 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives

Also Published As

Publication number Publication date
KR20010024084A (ko) 2001-03-26
DK1014986T3 (da) 2004-10-25
PL339368A1 (en) 2000-12-18
ES2222603T3 (es) 2005-02-01
SK2832000A3 (en) 2000-09-12
US6159970A (en) 2000-12-12
DE69825062T2 (de) 2005-08-25
AR013503A1 (es) 2000-12-27
PT1014986E (pt) 2004-10-29
WO1999013878A1 (en) 1999-03-25
NO20001400L (no) 2000-05-05
ATE270889T1 (de) 2004-07-15
MXPA00002616A (es) 2002-04-24
ZA987804B (en) 1999-03-18
EP1014986A1 (en) 2000-07-05
CN1278727A (zh) 2001-01-03
ID25789A (id) 2000-11-02
JP2001516719A (ja) 2001-10-02
BR9812236A (pt) 2000-07-18
KR20010024087A (ko) 2001-03-26
IL134775A0 (en) 2001-04-30
EP1014986B1 (en) 2004-07-14
IS5401A (is) 2000-03-14
AU9193198A (en) 1999-04-05
TR200000725T2 (tr) 2000-08-21
NO20001400D0 (no) 2000-03-17
SE9703376D0 (sv) 1997-09-18
AU752719B2 (en) 2002-09-26
HUP0100621A2 (hu) 2001-08-28
CA2302204A1 (en) 1999-03-25
DE69825062D1 (de) 2004-08-19

Similar Documents

Publication Publication Date Title
EE200000146A (et) Monoamiini oksüdaasi inhibiitori kombinatsioon h5-HT 1B antagonisti või osalise agonistiga
EE200000141A (et) 5-HT tagasihaarde inhibiitori kombinatsioon h5-HT 1B antagonisti või osalise agonistiga
ID18416A (id) Inhibitor metaloprotease diheterosiklik
NO985828L (no) Viskoelastisk overflateaktivt stoff basert pa gelingssammensetning for service-fluider i borehull
ID27574A (id) Inhibitor enzim
EE9900030A (et) HPPD geen ja inhibiitorid
PT977737E (pt) Quino- e quinazolinas antagonistas de crf
FI20085256L (fi) Retrovirusperäisten proteaasi-inhibiittoreiden yhdistelmä
DE69941559D1 (de) Enzymgemisch
DK0958287T3 (da) Sulfamidmetalloprotease-inhibitorer
DK0736525T3 (da) Benzonitriler som 5-HT-agonister og -antagonister
NO20003256D0 (no) ACE inhibitor-MMP inhibitor kombinasjoner
PT927183E (pt) Inibidores espirociclicos de metaloproteases
NO975073L (no) Lavtoksisk korrosjonshemmer
NO995545D0 (no) Korrosjonsinhibitor med lav toksisitet
ATE252547T1 (de) Matrixmetalloproteinaseinhibitoren
PT1194038E (pt) Composicao de quebra do repouso e sua utilizacao
ATE225346T1 (de) Fkbp inhibitoren
EE04142B1 (et) Selektiivse 5-HT 1A antagonisti kombinatsioon selektiivse h5-HT 1B antagonisti või osalise agonistiga
DE69720957T2 (de) Ace-hemmer
DK1115389T3 (da) Fructosamin-oxidase: antagonister og inhibitorer
SI1014985T1 (en) A combination of a 5-ht reuptake inhibitor and a h5-ht 1b antagonist or partial agonist
HK1032738A (en) A combination of a monoamine oxidase inhibitor and a h5-ht 1 beta antagonist or partial agonist
BR9800324A (pt) Bateria
ID18481A (id) 2-(3,5-difluorofenil)-3-(4-metilsulfonil)fenil)-2-siklopenten-1-on yang berguna sebagai inhibitor cox-2