DE122007000005I1 - Apolipoprotein-B Syntheseinhibitoren - Google Patents

Apolipoprotein-B Syntheseinhibitoren

Info

Publication number: DE122007000005I1
Authority: DE; Germany
Prior art keywords: apolipoprotein; synthesis inhibitors; inhibitors; synthesis
Prior art date: 1994-10-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

DE1995619995

Other languages

English (en)

Other versions

DE69519995D1 (en

DE69519995T2 (de

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Janssen Pharmaceutica NV

Original Assignee

Janssen Pharmaceutica NV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-27

Filing date

1995-10-19

Publication date

2007-04-26

1995-05-31 Priority claimed from US08/455,304 external-priority patent/US5521186A/en

1995-10-19 Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV

2007-04-26 Publication of DE122007000005I1 publication Critical patent/DE122007000005I1/de

Status Pending legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DE1995619995 1994-10-27 1995-10-19 Apolipoprotein-B Syntheseinhibitoren Pending DE122007000005I1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP94203120		1994-10-27
US08/455,304 US5521186A (en)	1994-10-27	1995-05-31	Apolipoprotein-β synthesis inhibitors
PCT/EP1995/004111 WO1996013499A1 (en)	1994-10-27	1995-10-19	Apolipoprotein-b synthesis inhibitors

Publications (1)

Publication Number	Publication Date
DE122007000005I1 true DE122007000005I1 (de)	2007-04-26

Family

ID=26136684

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DE1995619995 Pending DE122007000005I1 (de)	1994-10-27	1995-10-19	Apolipoprotein-B Syntheseinhibitoren
DE122007000005C Active DE122007000005I2 (de)	1994-10-27	1995-10-19	Apolipoprotein-b syntheseinhibitoren
DE69519995T Expired - Lifetime DE69519995T2 (de)	1994-10-27	1995-10-19	Apolipoprotein-b syntheseinhibitoren

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
DE122007000005C Active DE122007000005I2 (de)	1994-10-27	1995-10-19	Apolipoprotein-b syntheseinhibitoren
DE69519995T Expired - Lifetime DE69519995T2 (de)	1994-10-27	1995-10-19	Apolipoprotein-b syntheseinhibitoren

Country Status (30)

Country	Link
US (1)	US5929075A (de)
EP (1)	EP0788496B1 (de)
JP (1)	JP3025907B2 (de)
KR (1)	KR100227231B1 (de)
CN (1)	CN1068000C (de)
AP (1)	AP779A (de)
AT (1)	ATE198889T1 (de)
AU (1)	AU697744C (de)
BG (1)	BG63694B1 (de)
BR (1)	BR9509436A (de)
CA (1)	CA2203274C (de)
CY (1)	CY2256B1 (de)
CZ (1)	CZ286476B6 (de)
DE (3)	DE122007000005I1 (de)
DK (1)	DK0788496T3 (de)
ES (1)	ES2155535T3 (de)
FI (1)	FI119548B (de)
GR (1)	GR3035519T3 (de)
HR (1)	HRP950532B1 (de)
HU (1)	HU219862B (de)
IL (1)	IL115771A (de)
LU (1)	LU91306I2 (de)
NO (1)	NO311937B1 (de)
NZ (1)	NZ295353A (de)
OA (1)	OA10479A (de)
PT (1)	PT788496E (de)
RO (1)	RO118715B1 (de)
SK (1)	SK281908B6 (de)
TR (1)	TR199501295A2 (de)
WO (1)	WO1996013499A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20010023729A (ko) *	1997-11-03	2001-03-26	디르크 반테	지질 저하제 조성물
PL358909A1 (en) *	1998-04-27	2004-08-23	Janssen Pharmaceutica N.V.	Pellets having a core coated with a lipid lowering agent and a polymer
AU761032B2 (en) *	1998-12-22	2003-05-29	Janssen Pharmaceutica N.V.	S-oxide lipid lowering compounds
DE19945982A1 (de) *	1999-09-24	2001-03-29	Knoll Ag	Geschwindigkeitsbestimmte Partikel
US20050132022A1 (en) *	2003-12-12	2005-06-16	International Business Machines Corporation	Computer system with LAN-based I/O
AU2005205933B2 (en) *	2004-01-21	2010-02-18	Elanco Animal Health Ireland Limited	Mitratapide oral solution
US7649002B2 (en)	2004-02-04	2010-01-19	Pfizer Inc	(3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists
US7262318B2 (en) *	2004-03-10	2007-08-28	Pfizer, Inc.	Substituted heteroaryl- and phenylsulfamoyl compounds
AU2005230397B2 (en) *	2004-04-09	2010-04-08	Elanco Animal Health Ireland Limited	Intermittent dosing regimen for the treatment of overweight with MTP-inhibitors
US20050288340A1 (en) *	2004-06-29	2005-12-29	Pfizer Inc	Substituted heteroaryl- and phenylsulfamoyl compounds
PA8660701A1 (es)	2005-02-04	2006-09-22	Pfizer Prod Inc	Agonistas de pyy y sus usos
EP1890767A2 (de) *	2005-05-27	2008-02-27	Pfizer Products Inc.	Kombinationstherapie zur behandlung von fettleibigkeit oder aufrechterhaltung des gewichtverlusts
JP2009503050A (ja) *	2005-08-04	2009-01-29	ファイザー・リミテッド	ピペリジノイル−ピロリジンおよびピペリジノイル−ピペリジン化合物
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
AU2007219236B2 (en) *	2006-02-23	2012-06-21	Pfizer Limited	Melanocortin type 4 receptor agonist piperidinoylpyrrolidines
US8383660B2 (en)	2006-03-10	2013-02-26	Pfizer Inc.	Dibenzyl amine compounds and derivatives
AU2007320906A1 (en)	2006-11-13	2008-05-22	Pfizer Products Inc.	Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof
WO2008070496A2 (en)	2006-12-01	2008-06-12	Bristol-Myers Squibb Company	N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
ES2348530T3 (es) *	2007-05-25	2010-12-09	Janssen Pharmaceutica, N.V.	Síntesis mejorada de metanosulfonato de (2s-cis)-2-(bromometil)-2-(4-clorofenil)-1,3 dioxolan-4-metanol (éster).
CN102171206B (zh) *	2008-08-06	2014-06-25	辉瑞股份有限公司	作为mc4激动剂的二氮杂环庚烷和二氮杂环辛烷
EP2571871B1 (de) *	2010-05-19	2017-06-21	Sandoz AG	Verfahren zur Herstellung von chiralen Triazolonen
CR20200464A (es)	2018-03-08	2021-04-14	Incyte Corp	Compuestos diólicos de aminopirazina como inhibidores de pi3k-y
US11046658B2 (en)	2018-07-02	2021-06-29	Incyte Corporation	Aminopyrazine derivatives as PI3K-γ inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4313953A (en) *	1978-06-23	1982-02-02	Janssen Pharmaceutica, N.V.	Heterocyclic derivatives of (4-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
US4218458A (en) *	1978-06-23	1980-08-19	Janssen Pharmaceutica, N.V.	Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
US4766125A (en) *	1981-06-23	1988-08-23	Janssen Pharmaceutica N.V.	N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
US4619931A (en) *	1983-02-28	1986-10-28	Janssen Pharmaceutica, N.V.	[[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles
CA1292472C (en) *	1985-12-03	1991-11-26	Alfonsus Guilielmus Knaeps	Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl\|-1,3-dioxolan-2-yl\|methyl\|-1h-imidazoles and 1h-1,2,4-triazoles
NZ223799A (en) *	1987-03-25	1989-12-21	Janssen Pharmaceutica Nv	Azolylmethyl-dioxolanylmethoxyphenyl-piperazinyl-phenyl-triazolones and antimicrobial compositions
CA1331757C (en) *	1988-02-29	1994-08-30	Janssen Pharmaceutica Naamloze Vennootschap	5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
AU6359594A (en) *	1993-03-04	1994-09-26	Cytoven International N.V.	Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof
US5521186A (en) *	1994-10-27	1996-05-28	Janssen Pharmaceutica N.V.	Apolipoprotein-β synthesis inhibitors

1995
- 1995-10-19 PT PT95937804T patent/PT788496E/pt unknown
- 1995-10-19 BR BR9509436A patent/BR9509436A/pt not_active IP Right Cessation
- 1995-10-19 DE DE1995619995 patent/DE122007000005I1/de active Pending
- 1995-10-19 EP EP95937804A patent/EP0788496B1/de not_active Expired - Lifetime
- 1995-10-19 KR KR1019970702662A patent/KR100227231B1/ko not_active Expired - Fee Related
- 1995-10-19 DK DK95937804T patent/DK0788496T3/da active
- 1995-10-19 CN CN95195885A patent/CN1068000C/zh not_active Expired - Fee Related
- 1995-10-19 DE DE122007000005C patent/DE122007000005I2/de active Active
- 1995-10-19 NZ NZ295353A patent/NZ295353A/en not_active IP Right Cessation
- 1995-10-19 CZ CZ19971198A patent/CZ286476B6/cs not_active IP Right Cessation
- 1995-10-19 DE DE69519995T patent/DE69519995T2/de not_active Expired - Lifetime
- 1995-10-19 CA CA002203274A patent/CA2203274C/en not_active Expired - Fee Related
- 1995-10-19 RO RO97-00812A patent/RO118715B1/ro unknown
- 1995-10-19 HU HU9701956A patent/HU219862B/hu not_active IP Right Cessation
- 1995-10-19 JP JP8514288A patent/JP3025907B2/ja not_active Expired - Fee Related
- 1995-10-19 SK SK507-97A patent/SK281908B6/sk not_active IP Right Cessation
- 1995-10-19 WO PCT/EP1995/004111 patent/WO1996013499A1/en not_active Ceased
- 1995-10-19 ES ES95937804T patent/ES2155535T3/es not_active Expired - Lifetime
- 1995-10-19 AP APAP/P/1997/000968A patent/AP779A/en active
- 1995-10-19 AU AU38680/95A patent/AU697744C/en not_active Ceased
- 1995-10-19 AT AT95937804T patent/ATE198889T1/de active
- 1995-10-19 US US08/817,247 patent/US5929075A/en not_active Expired - Lifetime
- 1995-10-20 TR TR95/01295A patent/TR199501295A2/xx unknown
- 1995-10-26 IL IL11577195A patent/IL115771A/xx not_active IP Right Cessation
- 1995-10-27 HR HR950532A patent/HRP950532B1/xx not_active IP Right Cessation
1997
- 1997-04-10 BG BG101402A patent/BG63694B1/bg unknown
- 1997-04-24 NO NO19971895A patent/NO311937B1/no not_active IP Right Cessation
- 1997-04-25 FI FI971784A patent/FI119548B/fi not_active IP Right Cessation
- 1997-04-25 OA OA60997A patent/OA10479A/en unknown
2001
- 2001-03-05 GR GR20010400359T patent/GR3035519T3/el unknown
2002
- 2002-01-04 CY CY0200004A patent/CY2256B1/xx unknown
2007
- 2007-01-17 LU LU91306C patent/LU91306I2/fr unknown

Also Published As

Publication number	Publication date
US5929075A (en)	1999-07-27
KR100227231B1 (ko)	1999-11-01
JPH09511759A (ja)	1997-11-25
AU697744C (en)	2002-08-22
EP0788496A1 (de)	1997-08-13
CY2256B1 (en)	2003-07-04
NO971895D0 (no)	1997-04-24
CN1161695A (zh)	1997-10-08
MX9703074A (es)	1997-07-31
BG101402A (en)	1997-10-31
HRP950532A2 (en)	1997-08-31
FI971784L (fi)	1997-04-25
FI971784A0 (fi)	1997-04-25
AU697744B2 (en)	1998-10-15
DE122007000005I2 (de)	2008-04-24
BR9509436A (pt)	1998-01-06
AP779A (en)	1999-11-03
NO311937B1 (no)	2002-02-18
CZ286476B6 (en)	2000-04-12
NO971895L (no)	1997-04-24
OA10479A (en)	2002-04-09
GR3035519T3 (en)	2001-06-29
HU219862B (hu)	2001-08-28
IL115771A0 (en)	1996-01-19
SK50797A3 (en)	1998-04-08
LU91306I2 (fr)	2007-03-19
CA2203274A1 (en)	1996-05-09
WO1996013499A1 (en)	1996-05-09
AP9700968A0 (en)	1997-04-30
SK281908B6 (sk)	2001-09-11
CZ119897A3 (cs)	1998-03-18
ATE198889T1 (de)	2001-02-15
DE69519995D1 (en)	2001-03-01
PT788496E (pt)	2001-07-31
IL115771A (en)	2000-02-29
FI119548B (fi)	2008-12-31
BG63694B1 (bg)	2002-09-30
RO118715B1 (ro)	2003-09-30
CN1068000C (zh)	2001-07-04
EP0788496B1 (de)	2001-01-24
NZ295353A (en)	1998-08-26
HUT77360A (hu)	1998-03-30
JP3025907B2 (ja)	2000-03-27
HRP950532B1 (en)	2001-06-30
DE69519995T2 (de)	2001-08-23
AU3868095A (en)	1996-05-23
ES2155535T3 (es)	2001-05-16
TR199501295A2 (tr)	1996-06-21
DK0788496T3 (da)	2001-06-18
CA2203274C (en)	2002-02-19

Publication	Publication Date	Title
DE122007000005I1 (de)	2007-04-26	Apolipoprotein-B Syntheseinhibitoren
FI963597L (fi)	1996-11-14	Isoprenyylitransferaasi-inhibiittoreita
NO972930D0 (no)	1997-06-23	Fibronectin-adhesjonsinhibitorer
FI972160A0 (fi)	1997-05-21	Matriisimetalloproteaasi-inhibiittorit
FI964317A7 (fi)	1996-10-25	Tekijän-Xa-inhibiittoreita
DE69724809D1 (de)	2003-10-16	Refluxinhibitoren
FI955184A7 (fi)	1996-05-01	Bentsyylipiperidiinijohdannaiset
ATE230389T1 (de)	2003-01-15	Angiogenese inhibitoren
EE9700093A (et)	1997-10-15	Apolipoproteiin-B sünteesi inhiibitorid
FI964781L (fi)	1997-01-29	Uusia elastaasi-inhibiittoreita
BR9610514A (pt)	1999-03-30	Inibidores cicloantihelmínticos
CY2007006I1 (el)	2009-11-04	Αναστολεις συνθεσης απολιποπρωτεινης-β
FI1878U1 (fi)	1995-04-27	Maskmetspoe utan floete
FI943697A0 (fi)	1994-08-10	Riktningventil utan roera delar
ITRC940003A0 (it)	1994-05-26	Campanello per appuntamenti
UA852S (uk)	1995-06-30	Набір ваз
FI941265A0 (fi)	1994-03-17	Heterosyklisiä sulfoniamidotrombiini-inhibiittoreiHeterosyklisiä sulfoniamidotrombiini-inhibiittoreita ta