CN103876863A - Biological type artificial joint prosthesis - Google Patents
Biological type artificial joint prosthesis Download PDFInfo
- Publication number
- CN103876863A CN103876863A CN201410157193.1A CN201410157193A CN103876863A CN 103876863 A CN103876863 A CN 103876863A CN 201410157193 A CN201410157193 A CN 201410157193A CN 103876863 A CN103876863 A CN 103876863A
- Authority
- CN
- China
- Prior art keywords
- artificial joint
- joint prosthesis
- prosthese
- tissue engineering
- bone tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 32
- 108010048734 sclerotin Proteins 0.000 claims description 3
- 239000000463 material Substances 0.000 claims 3
- 239000002184 metal Substances 0.000 claims 1
- 239000002861 polymer material Substances 0.000 claims 1
- 238000005516 engineering process Methods 0.000 abstract description 2
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 230000003014 reinforcing effect Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 description 3
- 230000000975 bioactive effect Effects 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000003754 machining Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000012659 Joint disease Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/32—Joints for the hip
- A61F2/36—Femoral heads ; Femoral endoprostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a biological type artificial joint prosthesis. The biological type artificial joint prosthesis comprises a surface porous structure and an internal three-dimensional porous bone tissue engineering supporting structure. The surface porous structure is communicated with the internal three-dimensional porous bone tissue engineering supporting structure. According to the biological type artificial joint prosthesis, the bone tissue engineering technology is applied to the artificial joint prosthesis, and the artificial joint prosthesis and bone tissues can grow into a whole; because the structure between the artificial joint prosthesis and a bone interface is successive, functions and stress transfer of the artificial joint prosthesis are successive, the interface bonding strength can reach or even exceed the strength of the artificial joint prosthesis and the strength of a bone; consequently, the biological type artificial joint prosthesis can effectively shorten the reinforcing and fixing time to obtain permanent stability and can obviously reduce complications caused by prosthetic loosening and sinking, so the service life of the artificial joint can be prolonged.
Description
Technical field
The invention belongs to technical field of medical instruments, be specifically related to a kind of Biotype artificial articular prosthesis.
Background technology
Along with the raising of expanding economy and people's living standard, prosthetic replacement has been widely used in clinical and has obtained good clinical effectiveness, is acknowledged as effective Therapeutic Method of all kinds of ultimate joint diseases.But As time goes on, the complication such as the prosthetic loosening sinking being produced by this operation also become increasingly conspicuous, the clinical efficacy of operation and patient's quality of life are had a strong impact on.Once there is these adverse consequencess in patient, often need patient to carry out revision procedure treatment, this has not only increased patient's operation misery and medical expense, and clinical efficacy after overhauling also to can not show a candle to first operation desirable.
In order to solve the complication of the loosening sinking of artificial joint prosthesis, extend the service life of prosthese, Chinese scholars has been done a large amount of research work from aspects such as materialogy, physics and biomechanicss, show that biological activity is fixedly the desired combination mode between prosthese and osseous tissue, under this combination, between prosthese and osseous tissue, can become one by " growth ".Present continuously because structure between prosthese-osseous tissue interface makes function and Stress Transfer continuously, this kind of interface bond strength can meet or exceed prosthese and bone self intensity separately, therefore can shorten strong regular time permanent stable to obtain.
In prior art, mainly promote the osseous tissue prosthese of growing into by bioactive substance coating, but owing to being subject to the impact of coating and prosthese bond strength and bioactive substance degree of crystallinity etc., often cannot fundamentally realize biological activity fixes, the incidence rate that causes prosthetic loosening to sink is still very high, has had a strong impact on the service life of prosthese.
Summary of the invention
The object of the invention is to for deficiency of the prior art, propose a kind of Biotype artificial articular prosthesis becoming one by bone tissue engineering scaffold structure induction osseous tissue and prosthese " growth ".
To achieve these goals, the technical solution used in the present invention is.
The prosthese wall of artificial joint is become to loose structure with the Surface Machining of sclerotin contact portion, the three-dimensional porous bone tissue engineering supporting structure with certain porosity is processed in the inside of prosthese wall, and the three-dimensional porous bone tissue engineering supporting structure of the loose structure of prosthese wall surface and prosthese pars intramuralis connects mutually.
After this Biotype artificial articular prosthesis is implanted, osseous tissue just can be by the loose structure of the prosthese wall surface prosthese inside of growing into, the whole prosthese of growing under the induction of prosthese interior three-dimensional porous bone tissue engineering supporting structure, thereby artificial joint prosthesis and surrounding bone tissue " growth " are become one, shorten strong regular time of prosthese, reduce the complication that prosthetic loosening sinks, extended the service life of artificial joint.
Advantage of the present invention and beneficial effect are.
Bone tissue engineer is applied to artificial joint prosthesis by the present invention, between prosthese and osseous tissue, can become one by " growth ", because making function and Stress Transfer continuously, structure between prosthese-bone interface presents continuously, interface bond strength can meet or exceed prosthese and bone self intensity separately, therefore this Biotype artificial articular prosthesis not only can effectively shorten strong regular time to obtain permanent stablizing, and can obviously reduce the complication that prosthetic loosening sinks, extend the service life of artificial joint.
Accompanying drawing explanation
Fig. 1 is the artificial femoral hip prosthesis prosthetic surface of the present invention schematic diagram.
Fig. 2 is the artificial femoral hip prosthesis prosthese of the present invention schematic cross-sectional view.
In figure 1, prosthese wall; 2, the loose structure of prosthetic surface; 3, three-dimensional porous bone tissue engineering supporting structure.
The specific embodiment
Below in conjunction with accompanying drawing, the present invention is further described.
As depicted in figs. 1 and 2, the prosthese wall (1) of artificial joint is become to loose structure (2) with the Surface Machining of sclerotin contact portion, the three-dimensional porous bone tissue engineering supporting structure (3) with certain porosity is processed in the inside of prosthese wall (1), and the loose structure (2) on prosthese wall (1) surface and the three-dimensional porous bone tissue engineering supporting structure (3) of prosthese pars intramuralis connect mutually.
After this Biotype artificial articular prosthesis is implanted, osseous tissue just can be by the loose structure (2) on prosthese wall (1) the surface prosthese inside of growing into, the whole prosthese of growing under the induction of prosthese interior three-dimensional porous bone tissue engineering supporting structure (3), thereby artificial joint prosthesis and surrounding bone tissue " growth " are become one, shorten strong regular time of prosthese, reduce the complication that prosthetic loosening sinks, extended the service life of artificial joint.
Claims (7)
1. a Biotype artificial articular prosthesis, comprises surperficial loose structure and inner three-dimensional porous bone tissue engineering supporting structure, and the loose structure on described surface and inner three-dimensional porous bone tissue engineering supporting structure connect mutually.
2. a kind of Biotype artificial articular prosthesis according to claim 1, is characterized in that: the loose structure on surface can be distributed in whole prosthese and sclerotin contact portion, also can only be distributed in as required a certain part.
3. a kind of Biotype artificial articular prosthesis according to claim 1, is characterized in that: the fixing requirement of the loose structure on surface nothing in form and size.
4. a kind of Biotype artificial articular prosthesis according to claim 1, is characterized in that: inner three-dimensional porous bone tissue engineering supporting structure can be distributed in whole prosthese, also can only be distributed in as required a certain part in prosthese.
5. a kind of Biotype artificial articular prosthesis according to claim 1, is characterized in that: inner three-dimensional porous bone tissue engineering supporting structure has certain porosity.
6. a kind of Biotype artificial articular prosthesis according to claim 1, is characterized in that: it is characterized in that: the material of inner three-dimensional porous bone tissue engineering supporting structure is not limited to consistent with prosthese.
7. a kind of Biotype artificial articular prosthesis according to claim 1, it is characterized in that: it is characterized in that: the material of inner three-dimensional porous bone tissue engineering supporting structure can be metal, pottery, natural or synthesized polymer material, but is not limited to homogenous material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410157193.1A CN103876863A (en) | 2014-04-20 | 2014-04-20 | Biological type artificial joint prosthesis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410157193.1A CN103876863A (en) | 2014-04-20 | 2014-04-20 | Biological type artificial joint prosthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103876863A true CN103876863A (en) | 2014-06-25 |
Family
ID=50946212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410157193.1A Pending CN103876863A (en) | 2014-04-20 | 2014-04-20 | Biological type artificial joint prosthesis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103876863A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003013396A1 (en) * | 2001-08-11 | 2003-02-20 | Stanmore Implants Worldwide Ltd. | Surgical implant |
| CN101049516A (en) * | 2006-04-07 | 2007-10-10 | 中国科学院金属研究所 | Imbedded body in porous titanium of biologic medical use, and preparation method |
| CN101283936A (en) * | 2008-05-29 | 2008-10-15 | 上海交通大学 | Partial grid structure artificial joint prosthesis and preparation method thereof |
| CN101301230A (en) * | 2008-06-26 | 2008-11-12 | 上海交通大学 | Preparation method of artificial joint prosthesis with locally controllable porous structure |
| CN203354694U (en) * | 2013-04-26 | 2013-12-25 | 重庆润泽医药有限公司 | Riveted type artificial joint with good biocompatibility |
| CN103690275A (en) * | 2013-12-31 | 2014-04-02 | 南京航空航天大学 | Bamboo-structure-simulated hollow-hole bone-integrated artificial hip joint femoral component |
-
2014
- 2014-04-20 CN CN201410157193.1A patent/CN103876863A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003013396A1 (en) * | 2001-08-11 | 2003-02-20 | Stanmore Implants Worldwide Ltd. | Surgical implant |
| CN101049516A (en) * | 2006-04-07 | 2007-10-10 | 中国科学院金属研究所 | Imbedded body in porous titanium of biologic medical use, and preparation method |
| CN101283936A (en) * | 2008-05-29 | 2008-10-15 | 上海交通大学 | Partial grid structure artificial joint prosthesis and preparation method thereof |
| CN101301230A (en) * | 2008-06-26 | 2008-11-12 | 上海交通大学 | Preparation method of artificial joint prosthesis with locally controllable porous structure |
| CN203354694U (en) * | 2013-04-26 | 2013-12-25 | 重庆润泽医药有限公司 | Riveted type artificial joint with good biocompatibility |
| CN103690275A (en) * | 2013-12-31 | 2014-04-02 | 南京航空航天大学 | Bamboo-structure-simulated hollow-hole bone-integrated artificial hip joint femoral component |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140625 |