[go: up one dir, main page]

BR9105015A - Uso de,pelo menos,um composto,processo para o tratamento ou prevencao de processos degenerativos neuronais,processo para a triagem farmacologica de compostos neuronalmente ativos,processo para provocar lesoes neronais em animais cobaias e composicao farmceutica - Google Patents

Uso de,pelo menos,um composto,processo para o tratamento ou prevencao de processos degenerativos neuronais,processo para a triagem farmacologica de compostos neuronalmente ativos,processo para provocar lesoes neronais em animais cobaias e composicao farmceutica

Info

Publication number
BR9105015A
BR9105015A BR919105015A BR9105015A BR9105015A BR 9105015 A BR9105015 A BR 9105015A BR 919105015 A BR919105015 A BR 919105015A BR 9105015 A BR9105015 A BR 9105015A BR 9105015 A BR9105015 A BR 9105015A
Authority
BR
Brazil
Prior art keywords
compounds
neronal
injuries
prevention
causing
Prior art date
Application number
BR919105015A
Other languages
English (en)
Inventor
Francois Xavier Coude
Jacqueline Fournier
Umberto Guzzi
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Priority to BR919105015A priority Critical patent/BR9105015A/pt
Publication of BR9105015A publication Critical patent/BR9105015A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR919105015A 1990-05-22 1991-11-19 Uso de,pelo menos,um composto,processo para o tratamento ou prevencao de processos degenerativos neuronais,processo para a triagem farmacologica de compostos neuronalmente ativos,processo para provocar lesoes neronais em animais cobaias e composicao farmceutica BR9105015A (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR919105015A BR9105015A (pt) 1990-05-22 1991-11-19 Uso de,pelo menos,um composto,processo para o tratamento ou prevencao de processos degenerativos neuronais,processo para a triagem farmacologica de compostos neuronalmente ativos,processo para provocar lesoes neronais em animais cobaias e composicao farmceutica

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9006399A FR2662355B1 (fr) 1990-05-22 1990-05-22 Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
BR919105015A BR9105015A (pt) 1990-05-22 1991-11-19 Uso de,pelo menos,um composto,processo para o tratamento ou prevencao de processos degenerativos neuronais,processo para a triagem farmacologica de compostos neuronalmente ativos,processo para provocar lesoes neronais em animais cobaias e composicao farmceutica

Publications (1)

Publication Number Publication Date
BR9105015A true BR9105015A (pt) 1993-05-25

Family

ID=9396855

Family Applications (1)

Application Number Title Priority Date Filing Date
BR919105015A BR9105015A (pt) 1990-05-22 1991-11-19 Uso de,pelo menos,um composto,processo para o tratamento ou prevencao de processos degenerativos neuronais,processo para a triagem farmacologica de compostos neuronalmente ativos,processo para provocar lesoes neronais em animais cobaias e composicao farmceutica

Country Status (16)

Country Link
US (3) US5229389A (pt)
EP (2) EP0655247B1 (pt)
JP (2) JP2618115B2 (pt)
KR (1) KR0181330B1 (pt)
AT (2) ATE132369T1 (pt)
BR (1) BR9105015A (pt)
CA (2) CA2042974C (pt)
CY (1) CY2283B1 (pt)
DE (2) DE69115989T2 (pt)
DK (2) DK0458696T3 (pt)
FR (1) FR2662355B1 (pt)
HU (1) HU208922B (pt)
IE (1) IE911707A1 (pt)
IL (3) IL112167A (pt)
TW (1) TW216771B (pt)
ZA (1) ZA913865B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0192386A (ja) * 1987-10-05 1989-04-11 Hitachi Ltd 密閉循環型吸収式冷凍機及び吸収式冷凍機用吸収液
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
US5618822A (en) * 1990-05-23 1997-04-08 Sanofi N-substituted trifluoromethylphenyltetrahydropyridines, process for the preparation thereof, intermediates in said process and pharmaceutical compositions containing them
FR2662442A1 (fr) * 1990-05-23 1991-11-29 Midy Spa Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant.
US5557209A (en) * 1990-12-20 1996-09-17 Hewlett-Packard Company Identification of pin-open faults by capacitive coupling through the integrated circuit package
FR2672213B1 (fr) 1991-02-05 1995-03-10 Sanofi Sa Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.
FR2690158B1 (fr) * 1992-04-17 1994-07-22 Sanofi Elf Nouveau derive arylpiperidinique, procede pour sa preparation et compositions pharmaceutiques le contenant.
FR2702656B1 (fr) * 1993-03-18 1995-06-16 Sanofi Elf Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments cardioprotecteurs.
US5698565A (en) * 1995-06-09 1997-12-16 Hoffmann-La Roche Inc. Use of phenoxy-pyridine derivatives
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
FR2740343B1 (fr) * 1995-10-26 1999-01-22 Sanofi Sa Utilisation de la 1-(2-napht-2-yl-ethyl)-4- (3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de la sclerose laterale amyotrophique
NZ320355A (en) * 1995-10-26 2000-03-27 Sanofi Sa Use of 1-(2-naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6- tetrahydropyridine for preparing drugs for treating amyotrophic lateral sclerosis
JP2000507828A (ja) * 1996-03-29 2000-06-27 ザ トラスティーズ オブ ボストン ユニバーシティー アルツハイマー病の診断および治療法
US5891465A (en) * 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
FR2757160B1 (fr) * 1996-12-13 1999-03-12 Sanofi Sa 1-phenylalkyl-1,2,3,6-tetrahydropyridines
FR2757161B1 (fr) * 1996-12-13 1999-03-12 Sanofi Sa Diphenylalkyl-tetrahydropyridines
FR2757510B1 (fr) * 1996-12-23 2000-01-07 Sanofi Sa Forme microparticulaire d'un derive de tetrahydropyridine
FR2757512B1 (fr) * 1996-12-24 1999-03-12 Sanofi Sa Utilisation de benzoylalkyl-1-1,2,3,6-tetrahydropyridines
CZ275399A3 (cs) * 1997-02-03 1999-12-15 Sanofi-Synthelabo Použití 1-[4-(3-trifluormethylfenyl)-1,2,3,6-tetrahydropyrid-1-yl]-2-(6,7-dimethoxynaft-2-yl)ethanu pro výrobu léčiv s neurotrofní aktivitou
FR2762514B1 (fr) 1997-04-29 1999-10-22 Sanofi Sa Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
FR2771007B1 (fr) * 1997-11-14 2000-12-01 Sanofi Sa Association de principes actifs pour le traitement de la demence senile du type alzheimer
CO4980891A1 (es) * 1997-11-14 2000-11-27 Sanofi Sa Asociacion de principios activos para el tratamiento de la demencia senil de tipo azheimer
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
TWI237035B (en) * 1998-07-24 2005-08-01 Polyplastics Co Polyacetal copolymer
KR101130212B1 (ko) * 2002-03-27 2012-04-13 파이토팜 피엘씨 사포게닌 및 그 유도체의 치료 방법 및 사용법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.

Also Published As

Publication number Publication date
AU7713391A (en) 1991-11-28
KR910019617A (ko) 1991-12-19
US5270320A (en) 1993-12-14
ATE132369T1 (de) 1996-01-15
CA2042974A1 (en) 1991-11-22
DK0655247T3 (da) 2002-02-18
JPH09132535A (ja) 1997-05-20
TW216771B (pt) 1993-12-01
EP0655247A1 (fr) 1995-05-31
ZA913865B (en) 1992-02-26
EP0458696B1 (fr) 1996-01-03
JPH04226917A (ja) 1992-08-17
HU911729D0 (en) 1991-12-30
HUT59824A (en) 1992-07-28
ATE207747T1 (de) 2001-11-15
DE69115989D1 (de) 1996-02-15
KR0181330B1 (ko) 1999-03-20
HK1001471A1 (en) 1998-06-19
DK0458696T3 (da) 1996-05-20
JP2954029B2 (ja) 1999-09-27
HU208922B (en) 1994-02-28
IE20011078A1 (en) 2002-03-20
FR2662355B1 (fr) 1994-11-10
IL112167A0 (en) 1995-03-15
DE69132797T2 (de) 2002-05-29
EP0458696A2 (fr) 1991-11-27
CA2042974C (en) 2002-09-17
IL98175A (en) 1996-01-19
EP0458696A3 (en) 1992-03-18
AU636488B2 (en) 1993-04-29
CY2283B1 (en) 2003-07-04
FR2662355A1 (fr) 1991-11-29
JP2618115B2 (ja) 1997-06-11
EP0655247B1 (fr) 2001-10-31
DE69132797D1 (de) 2001-12-06
CA2365832A1 (en) 1991-11-23
US5468753A (en) 1995-11-21
IE911707A1 (en) 1991-12-04
IL98175A0 (en) 1992-06-21
DE69115989T2 (de) 1996-08-22
IL112167A (en) 1996-01-31
CA2365832C (en) 2007-08-07
US5229389A (en) 1993-07-20

Similar Documents

Publication Publication Date Title
BR9105015A (pt) Uso de,pelo menos,um composto,processo para o tratamento ou prevencao de processos degenerativos neuronais,processo para a triagem farmacologica de compostos neuronalmente ativos,processo para provocar lesoes neronais em animais cobaias e composicao farmceutica
DE69100547D1 (de) Methode und Vorrichtung zum elektrochemischen Bearbeiten der Spritzöffnungen von Brennstoff-Einspritzdüsen.
BR9002939A (pt) Derivado de n-fenil-pirazol,processo para prepara-lo,composicao pesticida e metodo para combater pragas de artopodes,nematoides,helmintas ou protozoarios
BR8805127A (pt) Processo para a obtencao de substancias de aperfeicoada acao inseticida e respectiva composicao inseticida
AR243600A1 (es) Un aparato para el tratamiento de muestras biologicas y microbiologicas.
MX163077B (es) Metodo para identificar y caracterizar organismos desconocidos el cual no es utilizado como metodo de diagnostico en relacion a humanos,animales o vegetales
DE69022733D1 (de) Verfahren und Vorrichtung zum Steuern der Bearbeitung von Geflügel.
BR9307292A (pt) Material absorvente de água polimérico processo para preparar um material absorvente de fluideo aquoso material absorvente de fluideo aquoso material absorvente de fluido aquoso e método para usar um material absorvente de fluido aquoso
DE69300574D1 (de) Vorrichtung zum Halten von Schlachtgeflügel.
BR8400348A (pt) Sal de derivado organofosforado,processo para sua preparacao,composicoes fungicidas e/ou bactericidas e processo para o tratamento de plantas
DE69325127D1 (de) Vorrichtung zum transportieren von schlachtttieren insbesondere geflügel
FI894081A7 (fi) Menetelmä ja laite eläinlihan, varsinkin kalan käsittelemiseksi
DE59005066D1 (de) Verfahren und Vorrichtung zum Keimfreimachen, Desinfizieren und/oder Trocknen.
DE69012808D1 (de) Vorrichtung zur behandlung von lebenden fischen und fischbrut und deren verwendung.
DE3874429D1 (de) Verfahren zur entfernung von chloridionen, die in kontaminierten festen abfaellen, wie mit aktiniden verunreinigten verbrennungsrueckstaenden, enthalten sind.
DE68910163D1 (de) Verfahren zur Bekämpfung von biologischen Verschmutzungen bei der Erdölförderung.
DE68920592D1 (de) Vorrichtung zum ausbluten von schlachttieren.
DE59001215D1 (de) Schneidwalze oder stanzzylinder und verfahren zum herstellen von solchen.
DE4293122T1 (de) Vorrichtung zum Behandeln von Rückgratsbeschwerden eines Tieres, insbesondere eines Pferdes
BR8207036A (pt) Processo para tratamento de materiais celulosicos antes de sua sacarificacao enzimatica
DE3786532D1 (de) Vorrichtung zur behandlung eines numerischen steuerprogrammes.
KR910005841U (ko) 폐액 연소방식에 의한 분뇨, 축산폐수, 산업폐수처리장치
BR8301517A (pt) 2-(nitrometileno)-tetra-hidro-2h-1,3-tiazinas n-substituidas e processo para sua preparacao composicao pesticida e metodo para combater as pragas em locais infestados ou com possibilidade de serem infestados por essas pragas
DE59001893D1 (de) Verfahren zur zersetzung von abfallaugen aus absorptionsprozessen.
ATE101885T1 (de) Verfahren zur extraktion der chemischen bestandteile aus zersetztem lignocellulosischem material.

Legal Events

Date Code Title Description
EE Request for examination
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal