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BG62754B1 - Мукоадхезивна емулсия, съдържаща циклодекстрин - Google Patents

Мукоадхезивна емулсия, съдържаща циклодекстрин Download PDF

Info

Publication number
BG62754B1
BG62754B1 BG100955A BG10095596A BG62754B1 BG 62754 B1 BG62754 B1 BG 62754B1 BG 100955 A BG100955 A BG 100955A BG 10095596 A BG10095596 A BG 10095596A BG 62754 B1 BG62754 B1 BG 62754B1
Authority
BG
Bulgaria
Prior art keywords
cyclodextrin
composition
amount
itraconazole
emulsion
Prior art date
Application number
BG100955A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100955A (bg
Inventor
Peter Putteman
Marc Francois
Eric Snoeckx
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of BG100955A publication Critical patent/BG100955A/xx
Publication of BG62754B1 publication Critical patent/BG62754B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Materials For Medical Uses (AREA)
BG100955A 1994-05-18 1996-11-04 Мукоадхезивна емулсия, съдържаща циклодекстрин BG62754B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94201402 1994-05-18
PCT/EP1995/001760 WO1995031178A1 (en) 1994-05-18 1995-05-10 Mucoadhesive emulsions containing cyclodextrin

Publications (2)

Publication Number Publication Date
BG100955A BG100955A (bg) 1998-04-30
BG62754B1 true BG62754B1 (bg) 2000-07-31

Family

ID=8216883

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100955A BG62754B1 (bg) 1994-05-18 1996-11-04 Мукоадхезивна емулсия, съдържаща циклодекстрин

Country Status (29)

Country Link
US (1) US5814330A (et)
EP (1) EP0759741B1 (et)
JP (1) JP3862748B2 (et)
KR (1) KR100369703B1 (et)
CN (1) CN1091590C (et)
AP (1) AP731A (et)
AT (1) ATE174790T1 (et)
AU (1) AU680767B2 (et)
BG (1) BG62754B1 (et)
BR (1) BR9507873A (et)
CZ (1) CZ285606B6 (et)
DE (1) DE69506857T2 (et)
DK (1) DK0759741T3 (et)
EE (1) EE03304B1 (et)
ES (1) ES2127529T3 (et)
FI (1) FI964589A0 (et)
HU (1) HU218082B (et)
IL (1) IL113742A (et)
MY (1) MY113846A (et)
NO (1) NO309507B1 (et)
NZ (1) NZ285761A (et)
OA (1) OA10321A (et)
PL (1) PL179619B1 (et)
RO (1) RO117145B1 (et)
RU (1) RU2164418C2 (et)
SK (1) SK282623B6 (et)
TW (1) TW438601B (et)
WO (1) WO1995031178A1 (et)
ZA (1) ZA954023B (et)

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JP2002505661A (ja) * 1996-10-24 2002-02-19 ザ、プロクター、エンド、ギャンブル、カンパニー 体臭軽減方法及び組成物
US6416779B1 (en) * 1997-06-11 2002-07-09 Umd, Inc. Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
KR19990001564A (ko) 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
JP3696087B2 (ja) 1997-12-31 2005-09-14 チョンワエ ファーマ コーポレーション イトラコナゾール（ｉｔｒａｃｏｎａｚｏｌｅ）経口用製剤及びその製造方法
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
NZ330726A (en) * 1998-06-18 2000-10-27 Dec Res Intra-vaginal delivery unit or composition containing a cyclodextrin which improves absorbtion of 17-beta oestradiol or oestradiol benzoate
GB9920167D0 (en) * 1999-08-25 1999-10-27 Avery Dennison Corp Pressure sensitive adhesive compositions
WO2001034213A1 (en) * 1999-11-09 2001-05-17 The Procter & Gamble Company Cyclodextrin compositions for odor, insect and dust mite contol
US6835717B2 (en) 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
KR100388605B1 (ko) * 2000-06-13 2003-06-25 코오롱제약주식회사 용해도 및 용해속도가 향상된 이트라코나졸의 액상 조성물 및 이를 이용한 이트라코나졸 제제와 그 제조방법
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
PT1997478E (pt) 2001-02-15 2013-12-10 Access Pharma Inc Formulações líquidas para a prevenção e para o tratamento de doenças e distúrbios das mucosas
US7544348B2 (en) 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
CA2466148C (en) 2001-11-01 2013-01-08 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
CN100384865C (zh) * 2001-11-02 2008-04-30 嵌入治疗公司 用于rna干扰的治疗用途的方法及组合物
US20050042240A1 (en) * 2002-01-28 2005-02-24 Utterberg David S. High viscosity antibacterials
US20030144362A1 (en) * 2002-01-28 2003-07-31 Utterberg David S. High viscosity antibacterials for cannulae
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
RU2225612C2 (ru) * 2002-04-30 2004-03-10 Уфимский научно-исследовательский институт медицины труда и экологии человека Способ прогнозирования течения множественной миеломы
US6824763B2 (en) 2002-05-30 2004-11-30 Kimberly-Clark Worldwide, Inc. Anti-fungal powder having enhanced excipient properties
US7977532B2 (en) 2002-09-05 2011-07-12 The Procter & Gamble Company Tampon with clean appearance post use
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
SG146638A1 (en) * 2003-09-19 2008-10-30 Drugtech Corp Pharmaceutical delivery system
US20060024372A1 (en) * 2004-07-29 2006-02-02 Utterberg David S High viscosity antibacterials
US9028852B2 (en) * 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
WO2006036159A1 (en) * 2004-09-27 2006-04-06 Cargill, Incorporated Cyclodextrin inclusion complexes and methods of preparing same
AU2005314426A1 (en) 2004-12-10 2006-06-15 Talima Therapeutics, Inc. Compositions and methods for treating conditions of the nail unit
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
WO2006121979A2 (en) * 2005-05-09 2006-11-16 Drugtech Corporation Modified-release pharmaceutical compositions
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
JP2009522360A (ja) * 2006-01-05 2009-06-11 ドラッグテック コーポレイション 組成物およびその使用方法
US20070154516A1 (en) * 2006-01-05 2007-07-05 Drugtech Corporation Drug delivery system
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
AU2008321395B2 (en) 2007-11-13 2013-03-14 Viropharma Biologics Llc Corticosteroid compositions
US20090143343A1 (en) * 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
RU2499592C2 (ru) 2008-04-21 2013-11-27 Отономи, Инк. Фармацевтическая композиция для лечения ушных заболеваний
CN102105133B (zh) 2008-07-21 2015-06-17 奥德纳米有限公司 控制释放型耳结构调节和先天性免疫系统调节组合物以及治疗耳部病症的方法
US8784870B2 (en) 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
HUE051538T2 (hu) 2008-08-20 2021-03-01 Univ California Kortikoszteroidok a gyomor-bél traktus gyulladásos betegségeinek kezelésére
WO2014159060A1 (en) 2013-03-14 2014-10-02 Hallux, Inc. Method of treating infections, diseases or disorders of nail unit
CA2993645A1 (en) 2015-07-28 2017-02-02 Otonomy, Inc. Trkb or trkc agonist compositions and methods for the treatment of otic conditions
EP3478269A4 (en) 2016-06-29 2020-04-08 Otonomy, Inc. OTIC FORMULATIONS BASED ON TRIGLYCERIDES AND THEIR USES
LT3737233T (lt) 2018-01-09 2025-11-25 Augimo faktoriaus preparatai ausims
WO2019154895A1 (en) 2018-02-08 2019-08-15 Strekin Ag Gel formulation for preventing or treating hearing loss

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GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
EP0335545B2 (en) * 1988-03-29 1998-09-23 University Of Florida Pharmaceutical formulations for parenteral use
US5055303A (en) * 1989-01-31 1991-10-08 Kv Pharmaceutical Company Solid controlled release bioadherent emulsions
IT1250421B (it) * 1991-05-30 1995-04-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive.
WO1993015719A1 (en) * 1992-02-12 1993-08-19 Janssen Farmaceutici S.P.A. Liposomal itraconazole formulations
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US5324718A (en) * 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
FR2719999B1 (fr) * 1994-05-17 1996-08-02 Georges Serge Grimberg Composition pharmaceutique à base de gomme de guar et d'un antiacide neutralisant, à laquelle peut être ajoutée une série de principes actifs thérapeutiques.

Also Published As

Publication number Publication date
EE03304B1 (et) 2000-12-15
SK282623B6 (sk) 2002-10-08
NO964853L (no) 1996-11-15
PL179619B1 (pl) 2000-10-31
DE69506857D1 (de) 1999-02-04
US5814330A (en) 1998-09-29
FI964589L (fi) 1996-11-15
FI964589A7 (fi) 1996-11-15
HU218082B (hu) 2000-05-28
DE69506857T2 (de) 1999-08-05
HU9603188D0 (en) 1997-01-28
MY113846A (en) 2002-06-29
DK0759741T3 (da) 1999-08-23
AU2526495A (en) 1995-12-05
BG100955A (bg) 1998-04-30
ZA954023B (en) 1996-11-18
IL113742A (en) 1999-09-22
JP3862748B2 (ja) 2006-12-27
OA10321A (en) 1997-10-07
CN1091590C (zh) 2002-10-02
BR9507873A (pt) 1997-09-23
AU680767B2 (en) 1997-08-07
CZ336996A3 (en) 1997-02-12
ATE174790T1 (de) 1999-01-15
IL113742A0 (en) 1995-08-31
ES2127529T3 (es) 1999-04-16
RU2164418C2 (ru) 2001-03-27
HK1010688A1 (en) 1999-06-25
NO309507B1 (no) 2001-02-12
RO117145B1 (ro) 2001-11-30
AP731A (en) 1999-02-08
CN1148335A (zh) 1997-04-23
FI964589A0 (fi) 1996-11-15
NZ285761A (en) 1997-05-26
HUT76326A (en) 1997-08-28
SK146996A3 (en) 1997-05-07
NO964853D0 (no) 1996-11-15
CZ285606B6 (cs) 1999-09-15
EP0759741A1 (en) 1997-03-05
AP9600873A0 (en) 1996-10-31
KR100369703B1 (ko) 2003-04-16
WO1995031178A1 (en) 1995-11-23
TW438601B (en) 2001-06-07
JPH10500121A (ja) 1998-01-06
KR970702719A (ko) 1997-06-10
EP0759741B1 (en) 1998-12-23
PL317257A1 (en) 1997-04-01

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