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AR066406A1 - Defensina de planta quimerica - Google Patents

Defensina de planta quimerica

Info

Publication number
AR066406A1
AR066406A1 ARP080101619A ARP080101619A AR066406A1 AR 066406 A1 AR066406 A1 AR 066406A1 AR P080101619 A ARP080101619 A AR P080101619A AR P080101619 A ARP080101619 A AR P080101619A AR 066406 A1 AR066406 A1 AR 066406A1
Authority
AR
Argentina
Prior art keywords
defensin
modified
plant
nucleic acid
transgenic
Prior art date
Application number
ARP080101619A
Other languages
English (en)
Original Assignee
Hexima Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexima Ltd filed Critical Hexima Ltd
Publication of AR066406A1 publication Critical patent/AR066406A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Método general para reducir o eliminar un efecto toxico de la expresion de defensina en una planta transgénica hospedante. Además incluye un método para modificar un ácido nucleico que codifica una defensina, un ácido nucleico modificado por la misma y un defensina modificada codificada por la secuencia de ácido nucleico modificada. Incluye una planta transgénica que contiene y que expresa la secuencia de ácidos nucleicos que codifica la defensina modificada, exhibiendo la planta efectos toxicos de defensina reducidos o eliminados, en comparacion con las plantas transgénicas de otro modo comparables que expresan una defensina sin modificar. La defensina modificada se denomina una defensina quimérica que tiene un dominio de defensina maduro de una primera defensina de planta combinada con un dominio de propéptido C-terminal de una segunda defensina de planta o un péptido de translocacion vacuolar.
ARP080101619A 2007-04-20 2008-04-18 Defensina de planta quimerica AR066406A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91298407P 2007-04-20 2007-04-20

Publications (1)

Publication Number Publication Date
AR066406A1 true AR066406A1 (es) 2009-08-19

Family

ID=39874985

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080101619A AR066406A1 (es) 2007-04-20 2008-04-18 Defensina de planta quimerica

Country Status (10)

Country Link
US (1) US20090083880A1 (es)
EP (2) EP2148889A4 (es)
CN (1) CN101848938A (es)
AR (1) AR066406A1 (es)
AU (1) AU2008241364B2 (es)
BR (1) BRPI0810233A2 (es)
CA (1) CA2684575A1 (es)
MX (1) MX2009011287A (es)
WO (1) WO2008128289A1 (es)
ZA (1) ZA200907123B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1366168B1 (en) * 2001-02-08 2011-05-18 Hexima Limited Plant-derived molecules and genetic sequences encoding same and uses therefor
BRPI0712168A2 (pt) * 2006-05-25 2012-03-13 Hexima Ltd veìculo de expressão de multigenes, vetor de expressão de veìculo de expressão de multigenes, célula de planta, planta trnsgênica, vetor de transformação de planta, métodos de expressar concorrentemente duas a oito proteìnas e de expressar concorrentemente 3 a 8 protéinas em uma célula de planta
AR075257A1 (es) 2008-02-01 2011-03-23 Hexima Ltd Sistema de proteccion de plantas contra la infeccion por agentes patogenos
CN102131393A (zh) * 2008-08-05 2011-07-20 赫希玛有限公司 植物抗病原体系统
US9889184B2 (en) 2008-08-05 2018-02-13 Hexima Limited Anti-pathogen systems
CA2807836A1 (en) * 2010-09-01 2012-03-08 Pioneer Hi-Bred International, Inc. Vacuole targeting peptides and methods of use
WO2012106759A1 (en) * 2011-02-07 2012-08-16 Hexima Limited Modified plant defensins useful as anti-pathogenic agents
JP6457945B2 (ja) * 2012-11-23 2019-01-23 ヘキシマ リミテッドＨｅｘｉｍａ Ｌｉｍｉｔｅｄ 抗病原体方法
EP2992101B1 (en) 2013-04-29 2018-10-10 Agrosavfe N.V. Agrochemical compositions comprising antibodies binding to sphingolipids
WO2016071438A2 (en) 2014-11-05 2016-05-12 Agrosavfe Nv Transgenic plant comprising a polynucleotide encoding a variable domain of heavy-chain antibody
EP3536702A1 (en) * 2013-04-30 2019-09-11 The Donald Danforth Plant Science Center Antifungal plant proteins, peptides, and methods of use
US10231450B2 (en) 2014-04-23 2019-03-19 Hexima Limited Agents and methods for treatment of pathogens
JP2017517498A (ja) * 2014-04-24 2017-06-29 ヘキシマ リミテッド 薬剤および治療方法
CN110240638B (zh) * 2019-06-10 2021-11-05 山东农业大学 一种利用生物信息学方法构建的抗菌肽及其应用
CN116410276A (zh) * 2021-12-30 2023-07-11 江苏众红生物工程创药研究院有限公司 重组北艾花粉i型变应原及其制备方法和应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5100792A (en) * 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
US6268546B1 (en) * 1989-07-19 2001-07-31 Calgene Llc Ovary-tissue transcriptional factors
CA2106092A1 (en) * 1991-03-11 1992-09-17 Miguel De Bolle Biocidal proteins
US5446127A (en) * 1991-05-24 1995-08-29 Universidad Politecnica De Madrid Antipathogenic peptides and compositions containing the same
US5538525A (en) * 1991-08-29 1996-07-23 Zeneca Limited Biocidal proteins
ES2239754T3 (es) 1992-12-16 2005-10-01 Hexima Limited Inhibidor de proteinasas, precursor del mismo y secuencias geneticas que codifican para el mismo.
US6031153A (en) * 1995-01-23 2000-02-29 Novartis Ag Method for protecting plants
BR9612011A (pt) * 1995-12-13 1999-05-18 Zeneca Ltd Peptídeo antifungico sequencia de dna recombinante vetor sistema biológico planta composição antifúngica e processo para o combate a fungos ou a bacterias
GB9525474D0 (en) * 1995-12-13 1996-02-14 Zeneca Ltd Antifungal proteins
US6909032B2 (en) * 1996-01-31 2005-06-21 Commonwealth Scientific And Industrial Research Organisation DNA encoding a macadamia integrifolia anti-microbial protein, constructs comprising the same and plant material comprising the constructs
US5773696A (en) * 1996-03-29 1998-06-30 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
US6121436A (en) * 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
AUPO427596A0 (en) * 1996-12-20 1997-01-23 Cooperative Research Centre For Tropical Plant Pathology Anti-microbial protein
GB9818003D0 (en) 1998-08-18 1998-10-14 Zeneca Ltd Polynucleotide sequences
US6855865B2 (en) 1999-05-07 2005-02-15 E.I. Du Pont De Nemours And Company Nucleic acids encoding plant defensins and methods of use thereof
US6677503B1 (en) * 1999-06-23 2004-01-13 Pioneer Hi-Bred International, Inc. Sunflower anti-pathogene proteins and genes and their uses
US6770750B2 (en) * 1999-11-18 2004-08-03 Korea Kumho Petrochemical Co., Ltd. Small and cysteine rich antifungal defensin and thionin-like protein genes highly expressed in the incompatible interaction
EP1366168B1 (en) * 2001-02-08 2011-05-18 Hexima Limited Plant-derived molecules and genetic sequences encoding same and uses therefor
EP2270187A3 (en) 2001-06-22 2011-08-31 Pioneer Hi-Bred International, Inc. Defensin polynucleotides and methods of use
KR100718574B1 (ko) * 2001-11-02 2007-05-15 더 보잉 컴파니 압축 잔류 응력 패턴을 가진 용접 조인트를 형성하는 장치및 방법
US7462695B2 (en) * 2003-04-23 2008-12-09 Hexima Limited Insect chymotrypsin and inhibitors thereof
US20070197474A1 (en) * 2004-03-30 2007-08-23 Clinton William P Methods for controlling plants pathogens using N-phosphonomethylglycine
CA2594053A1 (en) * 2004-12-24 2006-06-29 Anne Rae Vacuole targeting peptide and nucleic acid
BRPI0712168A2 (pt) * 2006-05-25 2012-03-13 Hexima Ltd veìculo de expressão de multigenes, vetor de expressão de veìculo de expressão de multigenes, célula de planta, planta trnsgênica, vetor de transformação de planta, métodos de expressar concorrentemente duas a oito proteìnas e de expressar concorrentemente 3 a 8 protéinas em uma célula de planta

Also Published As

Publication number Publication date
AU2008241364B2 (en) 2013-03-21
EP2148889A1 (en) 2010-02-03
CA2684575A1 (en) 2008-10-30
BRPI0810233A2 (pt) 2014-10-29
MX2009011287A (es) 2010-02-18
US20090083880A1 (en) 2009-03-26
EP2762498A1 (en) 2014-08-06
ZA200907123B (en) 2010-07-28
WO2008128289A1 (en) 2008-10-30
CN101848938A (zh) 2010-09-29
AU2008241364A1 (en) 2008-10-30
EP2148889A4 (en) 2010-06-23

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