AR047438A1 - Sal amina de derivado de carboestirilo - Google Patents
Sal amina de derivado de carboestiriloInfo
- Publication number
- AR047438A1 AR047438A1 ARP050100199A ARP050100199A AR047438A1 AR 047438 A1 AR047438 A1 AR 047438A1 AR P050100199 A ARP050100199 A AR P050100199A AR P050100199 A ARP050100199 A AR P050100199A AR 047438 A1 AR047438 A1 AR 047438A1
- Authority
- AR
- Argentina
- Prior art keywords
- derivative
- salt
- carboestirile
- amina
- bond
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title 1
- 125000005606 carbostyryl group Chemical group 0.000 abstract 2
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 2
- -1 amine salt Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000013011 aqueous formulation Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente provee una sal amina de un derivado de carboestirilo formada desde un derivado de carboestirilo representado por la formula (1) [en donde es R un átomo halogeno; la posicion sustituida de la cadena lateral es la posicion 3 o 4 en el esqueleto de carboestirilo; y el enlace entre la posicion 3 y 4 del esqueleto de carboestirilo es un enlace simple o un enlace doble] y una amina; y la presente es util como droga para tratar diversas enfermedades, especialmente como formulaciones acuosas debido a una solubilidad en agua superior y efectos farmacologicos superiores.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004013402 | 2004-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR047438A1 true AR047438A1 (es) | 2006-01-18 |
Family
ID=34805383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050100199A AR047438A1 (es) | 2004-01-21 | 2005-01-20 | Sal amina de derivado de carboestirilo |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7732611B2 (es) |
| EP (2) | EP1706383B1 (es) |
| JP (1) | JP4516962B2 (es) |
| KR (1) | KR100844762B1 (es) |
| CN (1) | CN1934086B (es) |
| AR (1) | AR047438A1 (es) |
| AT (1) | ATE549318T1 (es) |
| AU (1) | AU2005206430B2 (es) |
| BR (1) | BRPI0506982A (es) |
| CA (1) | CA2553231C (es) |
| CY (2) | CY1112723T1 (es) |
| DK (2) | DK2253619T3 (es) |
| ES (2) | ES2382133T3 (es) |
| HU (1) | HUE027990T2 (es) |
| MY (1) | MY148416A (es) |
| PL (2) | PL2253619T3 (es) |
| PT (2) | PT1706383E (es) |
| RU (1) | RU2372336C2 (es) |
| SG (1) | SG149854A1 (es) |
| SI (2) | SI2253619T1 (es) |
| TW (1) | TWI340650B (es) |
| WO (1) | WO2005070892A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187197B1 (en) * | 1998-10-28 | 2001-02-13 | Marvin Haddock | Multi-stage engine coolant recycling process |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| WO2009022674A1 (en) * | 2007-08-10 | 2009-02-19 | Otsuka Pharmaceutical Co., Ltd. | Medical composition containing rebamipide |
| WO2009126695A2 (en) * | 2008-04-08 | 2009-10-15 | Dynamis Therapeutics, Inc. | Method for treating or preventing dry eye disorders using alkylamino-polyhydroxyalkanes |
| TWI495634B (zh) * | 2008-06-19 | 2015-08-11 | Otsuka Pharma Co Ltd | 醫藥組成物 |
| WO2012114317A1 (en) * | 2011-02-25 | 2012-08-30 | Nuformix Limited | Novel rebamipide complexes and cocrystals |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS517614Y2 (es) * | 1971-02-12 | 1976-03-01 | ||
| FI80022C (fi) | 1982-07-05 | 1990-04-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat. |
| JPS597168A (ja) | 1982-07-05 | 1984-01-14 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| KR0180248B1 (ko) * | 1991-06-07 | 1999-03-20 | 오오쓰까 아끼히꼬 | 항당뇨병약품 |
| TW227558B (es) * | 1992-05-14 | 1994-08-01 | Otsuka Pharma Co Ltd | |
| US5415872A (en) | 1992-06-22 | 1995-05-16 | Digestive Care Inc. | Compositions of gastric acid-resistant microspheres containing salts of bile acids |
| JP2872546B2 (ja) * | 1992-11-26 | 1999-03-17 | 大塚製薬株式会社 | 腸粘膜障害保護剤 |
| DK0674515T3 (da) * | 1993-10-21 | 1999-12-20 | Otsuka Pharma Co Ltd | Anvendelse af carbostyrilderivater til fremstilling af et medikament til inhibering af interleukin-8 |
| WO1995012579A1 (en) | 1993-11-05 | 1995-05-11 | Otsuka Pharmaceutical Company, Limited | Bismuth salt of carbostyril derivatives for the treatment of peptic ulcers |
| JP3621463B2 (ja) * | 1995-04-26 | 2005-02-16 | 大塚製薬株式会社 | カルボスチリル誘導体ビスマス塩 |
| AR004214A1 (es) * | 1995-10-12 | 1998-11-04 | Otsuka Pharma Co Ltd | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
| GB9613455D0 (en) * | 1996-06-27 | 1996-08-28 | Aston Molecules Ltd | Analogues or derivatives of quercetin |
| JP2005519949A (ja) * | 2002-03-11 | 2005-07-07 | ノバルティス アクチエンゲゼルシャフト | ナテグリニドの塩 |
| KR20040104020A (ko) | 2003-06-02 | 2004-12-10 | 진양제약주식회사 | 신규 레바미피드 리지네이트와 레바미피드 아르기니네이트및 이 신규 레바미피드 리지네이트와 레바미피드아르기니네이트를 유효성분으로 함유하는 약학적 제제 |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| JP4719917B2 (ja) | 2007-03-30 | 2011-07-06 | 国立大学法人 岡山大学 | アズキ加工食品のアズキ原料品種判定方法 |
-
2005
- 2005-01-18 TW TW094101386A patent/TWI340650B/zh not_active IP Right Cessation
- 2005-01-19 MY MYPI20050200A patent/MY148416A/en unknown
- 2005-01-20 US US10/586,453 patent/US7732611B2/en not_active Expired - Fee Related
- 2005-01-20 SG SG200900369-0A patent/SG149854A1/en unknown
- 2005-01-20 BR BRPI0506982-3A patent/BRPI0506982A/pt not_active IP Right Cessation
- 2005-01-20 ES ES10174397T patent/ES2382133T3/es not_active Expired - Lifetime
- 2005-01-20 AT AT10174397T patent/ATE549318T1/de active
- 2005-01-20 EP EP05704144.4A patent/EP1706383B1/en not_active Expired - Lifetime
- 2005-01-20 RU RU2006129945/04A patent/RU2372336C2/ru not_active IP Right Cessation
- 2005-01-20 AU AU2005206430A patent/AU2005206430B2/en not_active Ceased
- 2005-01-20 HU HUE05704144A patent/HUE027990T2/en unknown
- 2005-01-20 EP EP10174397A patent/EP2253619B1/en not_active Expired - Lifetime
- 2005-01-20 SI SI200531494T patent/SI2253619T1/sl unknown
- 2005-01-20 PT PT57041444T patent/PT1706383E/pt unknown
- 2005-01-20 PT PT10174397T patent/PT2253619E/pt unknown
- 2005-01-20 SI SI200531992T patent/SI1706383T1/sl unknown
- 2005-01-20 PL PL10174397T patent/PL2253619T3/pl unknown
- 2005-01-20 JP JP2006520510A patent/JP4516962B2/ja not_active Expired - Lifetime
- 2005-01-20 DK DK10174397.9T patent/DK2253619T3/da active
- 2005-01-20 CA CA2553231A patent/CA2553231C/en not_active Expired - Fee Related
- 2005-01-20 KR KR1020067016600A patent/KR100844762B1/ko not_active Expired - Fee Related
- 2005-01-20 CN CN2005800086478A patent/CN1934086B/zh not_active Expired - Fee Related
- 2005-01-20 DK DK05704144.4T patent/DK1706383T3/en active
- 2005-01-20 WO PCT/JP2005/001034 patent/WO2005070892A1/en not_active Ceased
- 2005-01-20 AR ARP050100199A patent/AR047438A1/es not_active Application Discontinuation
- 2005-01-20 PL PL05704144T patent/PL1706383T3/pl unknown
- 2005-01-20 ES ES05704144.4T patent/ES2544327T3/es not_active Expired - Lifetime
-
2010
- 2010-04-26 US US12/662,610 patent/US8222276B2/en not_active Expired - Fee Related
-
2012
- 2012-05-11 CY CY20121100442T patent/CY1112723T1/el unknown
-
2015
- 2015-10-06 CY CY20151100891T patent/CY1116773T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12015502628A1 (en) | Pyrazolopyrrolidine derivatives and their use in the treatment of disease | |
| UY30438A1 (es) | Derivados n-sustituidos de 5-halo-4-[2-alquil-1-sustituidos-1h-imidazol-5-il]pirimidin-2-amina, composiciones-procesos para su preparacion y usos | |
| MX2015016344A (es) | Derivados de imidazo-pirrolidinona y su uso en el tratamiento de enfermedades. | |
| UY29633A1 (es) | Derivados de oxindol | |
| EA200870193A1 (ru) | Цитотоксические агенты, включающие новые производные томаймицина, и их терапевтическое применение | |
| MY148108A (en) | Medicaments for the treatment or prevention of fibrotic diseases | |
| EA201290191A1 (ru) | N1-ПИРАЗОЛОСПИРОКЕТОНОВЫЕ ИНГИБИТОРЫ АЦЕТИЛ-KoA-КАРБОКСИЛАЗЫ | |
| UY30334A1 (es) | Derivados de triazolopirazina | |
| EA201101672A1 (ru) | Замещенные производные аминомасляной кислоты в качестве ингибиторов неприлизина | |
| TW200728307A (en) | Novel spirochromanone derivatives | |
| AR068768A1 (es) | Derivados de tetrahidroquinolina para tratar trastornos por estres post - traumatico | |
| UY30411A1 (es) | Derivados sustituidos del acetato de 2,3,4,-tetrahidroimidazo-[1,5-a]-pirimidin-6-amina, composiciones farmacéuticas y aplicaciones | |
| MX2012000889A (es) | Compuesto biciclico y uso del mismo para propositos medicos. | |
| CO6480931A2 (es) | Sulfonamidas heterocíclicas, usos y composiciones farmacéuticas de las mismas. | |
| EA201691058A1 (ru) | Производные пирролопирролона и их применение для лечения заболеваний | |
| ATE543492T1 (de) | Behandlung von lungenkrebs | |
| UY30847A1 (es) | Uso de derivados de mononitrato de dianhidrohexita como agentes para el tratamiento de trastornos intestinales | |
| ECSP099506A (es) | Derivados de 2-quinolinona y 2 quinoxalinona y su utilización como agentes anti bacterianos | |
| AR047438A1 (es) | Sal amina de derivado de carboestirilo | |
| ECSP088621A (es) | Derivados de triazoloanilinopirimidina para uso como agentes antivirales | |
| BR112014004732A2 (pt) | composto benzotiazolona | |
| NI200600146A (es) | Composición farmacéutica de vinflunina para administración parenteral, proceso de preparación y su uso | |
| TW200635595A (en) | Medicaments for the treatment of prevention of fibrotic diseases | |
| CO6290762A2 (es) | Nuevos derivados quinazolin-2, 4-diona y una composicion farmaceutica para prevenir a tratar la enfermedad neurocerebral | |
| NO20070250L (no) | S-Tenatoprazol-natriummonohydratsalt og dennes anvendelse i form av en protonpumpe-inhibitor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |