AR028248A1 - Nuevos compuestos 2,3,4,5-tetrahidro-1h-(1,4) diazepino (1,7-a) indol - Google Patents

Nuevos compuestos 2,3,4,5-tetrahidro-1h-(1,4) diazepino (1,7-a) indol

Info

Publication number: AR028248A1
Authority: AR; Argentina
Prior art keywords: tetrahidro; diazepino; indol; new compounds; compounds
Prior art date: 2000-03-14

Application number

ARP010101164A

Other languages

English (en)

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-14

Filing date

2001-03-13

Publication date

2003-04-30

2001-03-13 Application filed by Upjohn Co filed Critical Upjohn Co

2003-04-30 Publication of AR028248A1 publication Critical patent/AR028248A1/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Immunology (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Gynecology & Obstetrics (AREA)
Obesity (AREA)
Pregnancy & Childbirth (AREA)
Diabetes (AREA)
Hematology (AREA)
Addiction (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Otolaryngology (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ARP010101164A 2000-03-14 2001-03-13 Nuevos compuestos 2,3,4,5-tetrahidro-1h-(1,4) diazepino (1,7-a) indol AR028248A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US18910300P	2000-03-14	2000-03-14

Publications (1)

Publication Number	Publication Date
AR028248A1 true AR028248A1 (es)	2003-04-30

Family

ID=22695943

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ARP010101164A AR028248A1 (es)	2000-03-14	2001-03-13	Nuevos compuestos 2,3,4,5-tetrahidro-1h-(1,4) diazepino (1,7-a) indol

Country Status (13)

Country	Link
US (2)	US6734301B2 (es)
EP (1)	EP1328525A2 (es)
JP (1)	JP2003529569A (es)
CN (1)	CN1418216A (es)
AR (1)	AR028248A1 (es)
AU (2)	AU2001243163B2 (es)
CA (1)	CA2402472A1 (es)
HK (1)	HK1054740A1 (es)
MX (1)	MXPA02008893A (es)
NZ (1)	NZ521389A (es)
PE (1)	PE20011231A1 (es)
WO (1)	WO2001072752A2 (es)
ZA (1)	ZA200207341B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003024967A2 (en) *	2001-09-19	2003-03-27	Aventis Pharma S.A.	Indolizines as kinase protein inhibitors
CL2004000826A1 (es)	2003-04-25	2005-03-04	Pfizer	Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129
BRPI0414313A (pt) *	2003-09-11	2006-11-07	Kemia Inc	inibidores de citocinas
EP2248524A3 (en)	2004-08-25	2011-03-09	Takeda Pharmaceutical Company Limited	Preventives/remedies for stress urinary incontinence and method of screening the same
US8158617B2 (en)	2006-05-16	2012-04-17	Takeda Pharmaceutical Company Limited	Fused heterocyclic compound and use thereof
EP2216023A4 (en)	2007-11-15	2013-03-13	Takeda Pharmaceutical	CONDENSED PYRIDINE DERIVATIVE AND ITS USE
SG173639A1 (en) *	2009-02-11	2011-09-29	Sunovion Pharmaceuticals Inc	Histamine h3 inverse agonists and antagonists and methods of use thereof
JP2013504581A (ja) *	2009-09-11	2013-02-07	スノヴィオンファーマシューティカルズインコーポレイテッド	ヒスタミンｈ３インバースアゴニストおよびアンタゴニストとその使用方法
JPWO2011071136A1 (ja)	2009-12-11	2013-04-22	アステラス製薬株式会社	線維筋痛症治療剤
CN103635230B (zh)	2011-05-12	2017-10-31	普罗蒂斯特斯治疗公司	蛋白内稳态调节剂
US9725427B2 (en)	2012-03-16	2017-08-08	Biohaven Pharmaceutical Holding Company Limited	Prodrugs of riluzole and their method of use
GB201401886D0 (en)	2014-02-04	2014-03-19	Lytix Biopharma As	Neurodegenerative therapies
HU230880B1 (hu) *	2015-04-15	2018-11-29	Richter Gedeon Nyrt	Indol származékok
WO2019131902A1 (ja)	2017-12-27	2019-07-04	武田薬品工業株式会社	腹圧性尿失禁および便失禁の治療薬
WO2024258995A2 (en) *	2023-06-13	2024-12-19	Delix Therapeutics, Inc.	Fused tetrahydroazepine psychoplastogens and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3867374A (en)	1968-06-05	1975-02-18	Mcneilab Inc	Diazepinoindoles
US3689503A (en)	1970-07-30	1972-09-05	Mcneilab Inc	Indole-2-carboxylates
SU460724A1 (ru)	1972-07-24	1989-07-30	Новокузнецкий научно-исследовательский химико-фармацевтический институт	Способ получени 2,3-дигидро-1Н-1,4-диазепино-(4,5-а)индол-2-онов
US4210590A (en)	1978-01-06	1980-07-01	Mcneil Laboratories, Incorporated	Reduction of indole compounds to indoline compounds
HU193083B (en)	1984-02-22	1987-08-28	Sandoz Ag	Process for preparing diazepinoindole derivatives further pharmaceutical compositions containing such compounds

2001
- 2001-03-08 MX MXPA02008893A patent/MXPA02008893A/es unknown
- 2001-03-08 HK HK03106482.9A patent/HK1054740A1/zh unknown
- 2001-03-08 AU AU2001243163A patent/AU2001243163B2/en not_active Ceased
- 2001-03-08 CA CA002402472A patent/CA2402472A1/en not_active Abandoned
- 2001-03-08 US US09/803,242 patent/US6734301B2/en not_active Expired - Fee Related
- 2001-03-08 NZ NZ521389A patent/NZ521389A/en unknown
- 2001-03-08 AU AU4316301A patent/AU4316301A/xx active Pending
- 2001-03-08 CN CN01806467A patent/CN1418216A/zh active Pending
- 2001-03-08 JP JP2001570662A patent/JP2003529569A/ja active Pending
- 2001-03-08 EP EP01916099A patent/EP1328525A2/en not_active Withdrawn
- 2001-03-08 WO PCT/US2001/004950 patent/WO2001072752A2/en not_active Ceased
- 2001-03-09 PE PE2001000227A patent/PE20011231A1/es not_active Application Discontinuation
- 2001-03-13 AR ARP010101164A patent/AR028248A1/es unknown
2002
- 2002-09-12 ZA ZA200207341A patent/ZA200207341B/xx unknown
2004
- 2004-01-20 US US10/761,070 patent/US20040209870A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US6734301B2 (en)	2004-05-11
HK1054740A1 (zh)	2003-12-12
JP2003529569A (ja)	2003-10-07
US20040209870A1 (en)	2004-10-21
AU2001243163B2 (en)	2004-11-04
AU4316301A (en)	2001-10-08
MXPA02008893A (es)	2003-02-10
NZ521389A (en)	2005-06-24
CN1418216A (zh)	2003-05-14
WO2001072752A2 (en)	2001-10-04
US20020002161A1 (en)	2002-01-03
EP1328525A2 (en)	2003-07-23
WO2001072752A3 (en)	2003-04-17
ZA200207341B (en)	2004-01-21
PE20011231A1 (es)	2001-12-06
CA2402472A1 (en)	2001-10-04

Publication	Publication Date	Title
DE60216115D1 (de)	2006-12-28	BENZIMIDAZO 4,5-föISOCHINOLINON-DERIVATE
CY2014041I1 (el)	2016-07-27	2,3-διυδρο-6-νιτροϊμιδαζο 2,1 -b-οξαζολια
DE60131971D1 (de)	2008-01-31	1,3,8-TRIAZA-SPIROi4,5 DECAN-4-ONDERIVATIVE ALS NEUROKININREZEPTORANTAGONISTEN
ATE298748T1 (de)	2005-07-15	(1,4')-bipiperidin verbindungen
DE60214428D1 (de)	2006-10-12	1, 4-dihydro-1, 4-diphenylpyridin-derivate
DE60225341D1 (de)	2008-04-10	Neue 1,2,4-triazolverbindung
ITRM20010537A0 (it)	2001-09-06	Motociclo.
ITRM20010523A0 (it)	2001-08-30	Motociclo.
AR028248A1 (es)	2003-04-30	Nuevos compuestos 2,3,4,5-tetrahidro-1h-(1,4) diazepino (1,7-a) indol
DE60210598D1 (de)	2006-05-24	3,7-DIAZABICYCLOc3.3.1Ü-FORMULIERUNGEN ALS ANTIARRHYTHMIKA
DE50107988D1 (de)	2005-12-15	Substituierte 1,2,3,4-tetrahydrochinolin-2-carbonsäurederivate
DE60025958D1 (de)	2006-04-20	14,15-beta-methylen substituierte androgene
ITTO20020005A0 (it)	2002-01-04	Motociclo.
BR0101022B1 (pt)	2009-08-11	motocicleta.
ITTO20020747A1 (it)	2003-02-25	Composizione.
ATE470655T1 (de)	2010-06-15	Substituierte 1,5-diaminopentan-3-ol-verbindungen
ITTO20010846A0 (it)	2001-09-05	Motociclo.
ES1048400Y (es)	2001-12-16	Bota-patin mejorada.
NL1021007A1 (nl)	2003-03-03	Beugelslot.
ITTO20020745A1 (it)	2003-02-25	Composizione.
ITTO20020348A0 (it)	2002-04-22	Motociclo.
IS7131A (is)	2004-01-29	Nýjar 2,4-díamínóþíasól afleiður
AR027974A1 (es)	2003-04-23	1-aril-ciclopropilmetilamino-1,3,5-triazinas substituidas
IS7299A (is)	2004-06-03	3,4-díhýdró-1H-ísókínólóín-2-ýl-afleiður
ES1045755Y (es)	2001-07-16	Lata mejorada.

Legal Events

Date	Code	Title	Description
2011-03-21	FB	Suspension of granting procedure