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NO970211L - Fremgangsmåte for racematspaltning av tramadol - Google Patents

Fremgangsmåte for racematspaltning av tramadol

Info

Publication number
NO970211L
NO970211L NO970211A NO970211A NO970211L NO 970211 L NO970211 L NO 970211L NO 970211 A NO970211 A NO 970211A NO 970211 A NO970211 A NO 970211A NO 970211 L NO970211 L NO 970211L
Authority
NO
Norway
Prior art keywords
tramadol
racemate cleavage
racemate
cleavage
Prior art date
Application number
NO970211A
Other languages
English (en)
Other versions
NO306059B1 (no
NO970211D0 (no
Inventor
Helmut Buschmann
Werner Winter
Ivars Graudums
Peter Jansen
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of NO970211D0 publication Critical patent/NO970211D0/no
Publication of NO970211L publication Critical patent/NO970211L/no
Publication of NO306059B1 publication Critical patent/NO306059B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10Separation; Purification; Stabilisation; Use of additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO970211A 1996-01-19 1997-01-17 Fremgangsmåte for racematspaltning av tramadol NO306059B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19601745A DE19601745C1 (de) 1996-01-19 1996-01-19 Verfahren zur Racematspaltung von Tramadol

Publications (3)

Publication Number Publication Date
NO970211D0 NO970211D0 (no) 1997-01-17
NO970211L true NO970211L (no) 1997-07-21
NO306059B1 NO306059B1 (no) 1999-09-13

Family

ID=7783112

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970211A NO306059B1 (no) 1996-01-19 1997-01-17 Fremgangsmåte for racematspaltning av tramadol

Country Status (31)

Country Link
US (1) US5723668A (no)
EP (1) EP0787715B1 (no)
JP (1) JPH09216858A (no)
KR (1) KR100505527B1 (no)
CN (1) CN1131203C (no)
AR (1) AR005391A1 (no)
AT (1) ATE189205T1 (no)
AU (1) AU711750B2 (no)
BR (1) BR9700094A (no)
CA (1) CA2195370C (no)
CO (1) CO4520185A1 (no)
CZ (1) CZ291775B6 (no)
DE (2) DE19601745C1 (no)
DK (1) DK0787715T3 (no)
ES (1) ES2145373T3 (no)
GR (1) GR3032489T3 (no)
HU (1) HU223067B1 (no)
IL (1) IL120028A (no)
IN (1) IN182218B (no)
MY (1) MY116583A (no)
NO (1) NO306059B1 (no)
NZ (1) NZ299999A (no)
PE (1) PE29898A1 (no)
PL (1) PL187403B1 (no)
PT (1) PT787715E (no)
RU (1) RU2192407C2 (no)
SI (1) SI0787715T1 (no)
SK (1) SK281612B6 (no)
UA (1) UA45343C2 (no)
UY (1) UY24439A1 (no)
ZA (1) ZA97369B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2130079B1 (es) 1997-07-10 2000-01-16 Esteve Labor Dr Resolucion de aminas
DK0996613T3 (da) * 1997-07-15 2003-03-03 Russinsky Ltd Fremstilling af rent cis-tramadol-hydrochlorid
DE19821039A1 (de) 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
GB9826540D0 (en) 1998-12-02 1999-01-27 Darwin Discovery Ltd Process
KR100342919B1 (ko) * 1999-10-21 2002-07-04 박노중 트랜스체 염산 트라마돌의 분리 제조방법
US20020143065A1 (en) * 2000-10-03 2002-10-03 Lirong Liu Developing a delivery system for multi-pharmaceutical active materials at various release rates
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
NZ528935A (en) * 2001-03-16 2004-10-29 Dmi Biosciences Inc Method of delaying ejaculation
US6649783B2 (en) * 2001-10-03 2003-11-18 Euro-Celtique, S.A. Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
WO2003048113A1 (en) 2001-11-30 2003-06-12 Sepracor Inc. Tramadol analogs and uses thereof
US20040248979A1 (en) * 2003-06-03 2004-12-09 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
RU2433999C2 (ru) 2005-01-26 2011-11-20 Аллерган, Инк. Амиды 3-арил-3-гидрокси-2-аминопропионовой кислоты, амиды 3-гетероарил-3-гидрокси-2-аминопропионовой кислоты и родственные соединения, обладающие обезболивающим и/или иммуностимулирующим действием
EP1785412A1 (en) 2005-11-14 2007-05-16 IPCA Laboratories Limited Tramadol recovery process
ES2384481T3 (es) * 2007-02-12 2012-07-05 Dmi Biosciences, Inc. Tratamiento de la eyaculación precoz y la disfunción eréctil co-morbidas
ES2384127T3 (es) 2007-02-12 2012-06-29 Dmi Biosciences, Inc. Reducción de los efectos secundarios del tramadol
DE102013009114A1 (de) 2013-05-29 2014-12-04 Franz Gerstheimer Pharmazeutische Zusammensetzung zur Überwindung von Metabolisierungsproblemen
KR102136004B1 (ko) 2018-06-18 2020-07-22 (주)센텍코리아 감지부의 잔존 수명을 추정할 수 있는 음주측정기

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528267A (en) * 1950-10-31 Eobeet j
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
IL50080A (en) * 1975-07-29 1979-07-25 Beecham Group Ltd 4-oxa-1-azabicyclo(3.2.0)heptan-7-one-2-car boxylic acid derivatives and their preparation
GB9017390D0 (en) * 1990-08-08 1990-09-19 Norgine Ltd Improvements in or relating to propylamine derivatives
JPH06122686A (ja) * 1992-10-12 1994-05-06 Fujisawa Pharmaceut Co Ltd ラセミ体の光学分割法

Also Published As

Publication number Publication date
JPH09216858A (ja) 1997-08-19
KR100505527B1 (ko) 2005-10-19
AU1223297A (en) 1997-07-24
UA45343C2 (uk) 2002-04-15
ES2145373T3 (es) 2000-07-01
GR3032489T3 (en) 2000-05-31
HUP9700141A3 (en) 2000-03-28
CA2195370A1 (en) 1997-07-20
EP0787715A1 (de) 1997-08-06
NZ299999A (en) 1998-01-26
SK6897A3 (en) 1997-08-06
CN1131203C (zh) 2003-12-17
MX9700483A (es) 1997-07-31
HU223067B1 (hu) 2004-03-01
CA2195370C (en) 2005-07-12
DE19601745C1 (de) 1997-10-09
SI0787715T1 (en) 2000-04-30
RU2192407C2 (ru) 2002-11-10
HU9700141D0 (en) 1997-03-28
PE29898A1 (es) 1998-08-08
PL187403B1 (pl) 2004-07-30
AR005391A1 (es) 1999-04-28
EP0787715B1 (de) 2000-01-26
PT787715E (pt) 2000-06-30
NO306059B1 (no) 1999-09-13
NO970211D0 (no) 1997-01-17
CZ291775B6 (cs) 2003-05-14
IN182218B (no) 1999-02-06
DK0787715T3 (da) 2000-04-25
AU711750B2 (en) 1999-10-21
DE59604295D1 (de) 2000-03-02
SK281612B6 (sk) 2001-05-10
MY116583A (en) 2004-02-28
PL318003A1 (en) 1997-07-21
CO4520185A1 (es) 1997-10-15
HUP9700141A2 (hu) 1998-01-28
CZ15697A3 (cs) 1998-05-13
ZA97369B (en) 1997-07-29
IL120028A (en) 1999-12-22
US5723668A (en) 1998-03-03
IL120028A0 (en) 1997-04-15
KR970059155A (ko) 1997-08-12
UY24439A1 (es) 1997-01-30
CN1161957A (zh) 1997-10-15
ATE189205T1 (de) 2000-02-15
BR9700094A (pt) 1998-09-22

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