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NO903001L - PROCEDURE FOR MANUFACTURING PHARMACEUTICAL PREPARATIONS WITH EXTENDED RELEASE. - Google Patents

PROCEDURE FOR MANUFACTURING PHARMACEUTICAL PREPARATIONS WITH EXTENDED RELEASE.

Info

Publication number
NO903001L
NO903001L NO90903001A NO903001A NO903001L NO 903001 L NO903001 L NO 903001L NO 90903001 A NO90903001 A NO 90903001A NO 903001 A NO903001 A NO 903001A NO 903001 L NO903001 L NO 903001L
Authority
NO
Norway
Prior art keywords
procedure
pharmaceutical preparations
extended release
manufacturing pharmaceutical
manufacturing
Prior art date
Application number
NO90903001A
Other languages
Norwegian (no)
Other versions
NO302928B1 (en
NO903001D0 (en
Inventor
David Bodmer
Jones Wing Fong
Thomas Kissel
Hawkins Valliant Maulding
Oskar Nagele
Jane Edna Pearson
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO903001D0 publication Critical patent/NO903001D0/en
Publication of NO903001L publication Critical patent/NO903001L/en
Priority to NO960075A priority Critical patent/NO960075D0/en
Priority to NO19960076A priority patent/NO318810B1/en
Publication of NO302928B1 publication Critical patent/NO302928B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO903001A 1989-07-07 1990-07-05 Process for the preparation of microparticles NO302928B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
NO960075A NO960075D0 (en) 1989-07-07 1996-01-08 Process for the preparation of a sustained-release pharmaceutical composition
NO19960076A NO318810B1 (en) 1989-07-07 1996-01-08 Process for the preparation of octreotide pamoate.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37702389A 1989-07-07 1989-07-07
US41134789A 1989-09-22 1989-09-22

Publications (3)

Publication Number Publication Date
NO903001D0 NO903001D0 (en) 1990-07-05
NO903001L true NO903001L (en) 1991-01-08
NO302928B1 NO302928B1 (en) 1998-05-11

Family

ID=27007654

Family Applications (2)

Application Number Title Priority Date Filing Date
NO903001A NO302928B1 (en) 1989-07-07 1990-07-05 Process for the preparation of microparticles
NO19983923A NO320444B1 (en) 1989-07-07 1998-08-26 Process for the preparation of a sustained release pharmaceutical composition

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO19983923A NO320444B1 (en) 1989-07-07 1998-08-26 Process for the preparation of a sustained release pharmaceutical composition

Country Status (27)

Country Link
JP (5) JPH0832624B2 (en)
KR (2) KR100303681B1 (en)
AT (1) AT406225B (en)
AU (2) AU641407B2 (en)
BE (1) BE1004486A3 (en)
CA (1) CA2020477C (en)
CH (1) CH685230A5 (en)
CY (1) CY1965A (en)
DE (2) DE4021517B4 (en)
DK (1) DK175849B1 (en)
FI (3) FI108611B (en)
FR (1) FR2649319A1 (en)
GB (2) GB2234896B (en)
GR (1) GR1001121B (en)
HK (2) HK97695A (en)
HU (2) HU221294B1 (en)
IE (2) IE64411B1 (en)
IL (3) IL131881A (en)
IT (1) IT1241460B (en)
LU (1) LU87764A1 (en)
MY (1) MY106722A (en)
NL (1) NL195027C (en)
NO (2) NO302928B1 (en)
NZ (1) NZ234384A (en)
PT (1) PT94628B (en)
SE (1) SE512992C2 (en)
SG (1) SG26416G (en)

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CH683149A5 (en) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Process for the preparation of microspheres of a biodegradable polymeric material.
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
DE4218510A1 (en) * 1992-06-02 1993-12-09 Pharmatech Gmbh Process for the preparation of biodegradable polyesters
AU4198793A (en) 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
CA2123144A1 (en) * 1993-05-10 1994-11-11 David Bodmer Stabilisation of pharmacologically active compounds in sustained release compositions
GB9310781D0 (en) * 1993-05-25 1993-07-14 Davis Stanley S Preparation of microparticles
US5603960A (en) * 1993-05-25 1997-02-18 O'hagan; Derek T. Preparation of microparticles and method of immunization
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US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
ATE192334T1 (en) 1995-11-09 2000-05-15 Microbiological Res Authority MICRO-ENCAPSULED DNA FOR VACCINATION AND GENE THERAPY
DE19545257A1 (en) 1995-11-24 1997-06-19 Schering Ag Process for the production of morphologically uniform microcapsules and microcapsules produced by this process
US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US7107268B1 (en) 1998-11-12 2006-09-12 Printable Technologies, Inc. Centralized system and method for managing enterprise operations
US6226656B1 (en) 1998-11-12 2001-05-01 Sourcefinder, Inc. System and method for creating, generating and processing user-defined generic specs
US6204308B1 (en) 1999-03-01 2001-03-20 Novartis Ag Organic compounds
EP1044683A1 (en) * 1999-04-15 2000-10-18 Debio Recherche Pharmaceutique S.A. One-step dispersion method for the microencapsulation of water soluble substances
US6461631B1 (en) * 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
KR100392501B1 (en) * 2000-06-28 2003-07-22 동국제약 주식회사 Preparation Method for Sustained Release Microparticles by Multiple Emulsion Method and Micropartic les Thereof
US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
CA2432900C (en) 2000-12-21 2007-09-11 Nektar Therapeutics Induced phase transition method for the production of microparticles containing hydrophilic active agents
US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
PE20050285A1 (en) * 2003-06-24 2005-06-09 Novartis Ag PHARMACEUTICAL COMPOSITION INCLUDING CYCLIC ANALOGS OF SOMATOSTATIN
DK1660039T3 (en) * 2003-07-18 2017-01-16 Oakwood Laboratories L L C PREVENTION OF REDUCTION OF THE POLYMER MOLECULE WEIGHT, THE PREPARATION OF PURPOSES AND GELING IN POLYMER COMPOSITIONS
MY158342A (en) 2003-11-14 2016-09-30 Novartis Ag Pharmaceutical composition
US20070259047A1 (en) * 2004-02-26 2007-11-08 Yasuaki Ogawa Protein Sustained-Release Microparticle Preparation for Injection and Process for Producing the Same
DE102004053373A1 (en) * 2004-11-02 2006-05-04 Justus-Liebig-Universität Giessen Invention relating to nano / meso-fiber anisometric particles in the form of nano / meso-fiber tubes, cables and their curved or branched modifications
KR100741867B1 (en) * 2005-07-05 2007-07-24 전북대학교산학협력단 Method of Preparation of Double Layered Microspheres Using Oil-in-water and Solvent Evaporation
KR101245919B1 (en) * 2005-12-22 2013-03-20 노파르티스 아게 Sustained release formulation comprising octreotide and two or more polylactide-co-glycolide polymers
KR100816065B1 (en) * 2006-11-27 2008-03-24 동국제약 주식회사 Method for preparing sustained release microcapsules with excellent initial release control characteristics and microcapsules prepared by the same
RU2541104C2 (en) 2008-01-30 2015-02-10 Новартис Аг Prolonged release formulation containing octreotide and three linear polymers of poly(lactide-co-glycolic acid)
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
RU2013119811A (en) * 2010-09-30 2014-11-10 Эвоник Корпорейшн METHOD FOR REMOVING RESIDUAL ORGANIC SOLVENT FROM MICROPARTICLES
RU2013119810A (en) * 2010-09-30 2014-11-10 Эвоник Корпорейшн EMULSION METHOD FOR PRODUCING MICROPARTICLES WITH LOW CONTENT OF RESIDUAL SOLVENT
TW201605488A (en) 2013-10-15 2016-02-16 大塚製藥股份有限公司 Drug for preventing and/or treating polycystic kidney disease
KR102464650B1 (en) 2016-05-03 2022-11-10 엘에스일렉트릭(주) Current limiting device of circuit breaker
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
AU2017319728B2 (en) 2016-08-31 2024-09-05 Mapi Pharma Ltd Depot systems comprising glatiramer acetate
MX2019010174A (en) 2017-03-26 2019-10-15 Mapi Pharma Ltd Glatiramer depot systems for treating progressive forms of multiple sclerosis.

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Also Published As

Publication number Publication date
JPH07285853A (en) 1995-10-31
SE512992C2 (en) 2000-06-12
HU903974D0 (en) 1990-11-28
IE64411B1 (en) 1995-08-09
NO983923L (en) 1991-01-08
DK162590D0 (en) 1990-07-05
AU641407B2 (en) 1993-09-23
SG26416G (en) 1995-09-01
JPH0832624B2 (en) 1996-03-29
IT9048113A1 (en) 1992-01-05
JP2001233897A (en) 2001-08-28
FR2649319A1 (en) 1991-01-11
GB2234896B (en) 1994-01-19
IL94983A0 (en) 1991-06-10
NL9001537A (en) 1991-02-01
ATA144090A (en) 1999-08-15
NL195027B (en) 2003-08-01
HK197496A (en) 1996-11-08
NO320444B1 (en) 2005-12-05
BE1004486A3 (en) 1992-12-01
DE4042752B4 (en) 2009-05-07
AU2332195A (en) 1995-09-07
HU221294B1 (en) 2002-09-28
JPH08198771A (en) 1996-08-06
CY1965A (en) 1997-07-04
HUT54037A (en) 1991-01-28
IL94983A (en) 1999-08-17
FI108611B (en) 2002-02-28
NL195027C (en) 2003-12-02
SE9002364D0 (en) 1990-07-05
KR100303681B1 (en) 2002-05-16
HK97695A (en) 1995-06-23
HU211602A9 (en) 1995-12-28
DE4021517B4 (en) 2009-04-09
FI20000059L (en) 2000-01-12
AU687553B2 (en) 1998-02-26
FR2649319B1 (en) 1994-12-09
DE4021517A1 (en) 1991-01-17
FI109334B (en) 2002-07-15
GR900100513A (en) 1991-12-10
JPH07309897A (en) 1995-11-28
GB2234896A (en) 1991-02-20
IL131880A (en) 2001-12-23
IL131881A (en) 2001-12-23
LU87764A1 (en) 1992-03-11
IE64216B1 (en) 1995-07-26
SE9002364L (en) 1991-01-08
GB2265311B (en) 1994-02-09
CH685230A5 (en) 1995-05-15
MY106722A (en) 1995-07-31
KR910002430A (en) 1991-02-25
IT1241460B (en) 1994-01-17
AU5874690A (en) 1991-01-10
DK175849B1 (en) 2005-03-29
IE902435A1 (en) 1991-02-13
PT94628A (en) 1991-03-20
GR1001121B (en) 1993-04-28
JP2931773B2 (en) 1999-08-09
GB9014704D0 (en) 1990-08-22
CA2020477C (en) 2000-11-21
IT9048113A0 (en) 1990-07-05
PT94628B (en) 1997-06-30
GB9306204D0 (en) 1993-05-19
KR100442931B1 (en) 2004-08-02
NO302928B1 (en) 1998-05-11
NZ234384A (en) 1994-05-26
DK162590A (en) 1991-01-08
GB2265311A (en) 1993-09-29
NO983923D0 (en) 1998-08-26
CA2020477A1 (en) 1991-01-08
FI903429A0 (en) 1990-07-06
FI20000060L (en) 2000-01-12
NO903001D0 (en) 1990-07-05
JPH0368511A (en) 1991-03-25
FI109543B (en) 2002-08-30
AT406225B (en) 2000-03-27

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