NL301307I2 - fruquintinib - Google Patents

fruquintinib

Info

Publication number: NL301307I2
Authority: NL; Netherlands
Prior art keywords: fruquintinib
Prior art date: 2014-09-10

Application number

NL301307C

Other languages

English (en)

Original Assignee

Hutchmed Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-09-10

Filing date

2024-12-18

Publication date

2024-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55458346&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL301307(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2024-12-18 Application filed by Hutchmed Ltd filed Critical Hutchmed Ltd

2024-12-31 Publication of NL301307I2 publication Critical patent/NL301307I2/nl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NL301307C 2014-09-10 2024-12-18 fruquintinib NL301307I2 (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CN201410456350.9A CN105461702A (zh)	2014-09-10	2014-09-10	6-(6,7-二甲氧基喹唑啉-4-基氧基)-n,2-二甲基苯并呋喃-3-甲酰胺晶型
PCT/CN2015/089035 WO2016037550A1 (en)	2014-09-10	2015-09-07	Crystalline forms of 6- ( (6, 7-dimethoxyquinazolin-4-yl) oxy) -n,2-dimethylbenzofuran-3-carboxamide

Publications (1)

Publication Number	Publication Date
NL301307I2 true NL301307I2 (nl)	2024-12-31

Family

ID=55458346

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL301307C NL301307I2 (nl)	2014-09-10	2024-12-18	fruquintinib

Country Status (35)

Country	Link
US (4)	US10519142B2 (nl)
EP (1)	EP3191475B1 (nl)
JP (2)	JP6655608B2 (nl)
KR (2)	KR20170042662A (nl)
CN (3)	CN105461702A (nl)
AU (1)	AU2015316010B2 (nl)
BR (1)	BR112017004000B1 (nl)
CA (1)	CA2958666C (nl)
CL (1)	CL2017000540A1 (nl)
CY (1)	CY1123892T1 (nl)
DK (1)	DK3191475T3 (nl)
EA (1)	EA034730B1 (nl)
ES (1)	ES2819242T3 (nl)
FI (1)	FIC20240047I1 (nl)
FR (1)	FR24C1055I2 (nl)
HR (1)	HRP20201501T1 (nl)
HU (2)	HUE050580T2 (nl)
IL (1)	IL250647B (nl)
LT (2)	LT3191475T (nl)
MX (1)	MX370791B (nl)
MY (1)	MY176618A (nl)
NL (1)	NL301307I2 (nl)
NO (1)	NO2024061I1 (nl)
PE (1)	PE20170661A1 (nl)
PH (1)	PH12017500451A1 (nl)
PL (1)	PL3191475T3 (nl)
PT (1)	PT3191475T (nl)
RS (1)	RS60829B1 (nl)
SG (1)	SG11201701544UA (nl)
SI (1)	SI3191475T1 (nl)
SM (1)	SMT202000511T1 (nl)
TW (1)	TWI718105B (nl)
UA (1)	UA120371C2 (nl)
WO (1)	WO2016037550A1 (nl)
ZA (1)	ZA201701320B (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN105461702A (zh) *	2014-09-10	2016-04-06	和记黄埔医药（上海）有限公司	6-(6,7-二甲氧基喹唑啉-4-基氧基)-n,2-二甲基苯并呋喃-3-甲酰胺晶型
CN111164085B (zh)	2017-09-29	2023-04-04	杭州领业医药科技有限公司	瑞博西林的共晶和瑞博西林单琥珀酸盐的共晶、其制备方法、组合物和用途
CN116987069B (zh) *	2018-03-30	2025-12-02	杭州领业医药科技有限公司	呋喹替尼的共晶、其制备方法、组合物和用途
CN111184698A (zh) *	2018-11-15	2020-05-22	和记黄埔医药（上海）有限公司	呋喹替尼制剂及其应用
JP7460604B2 (ja)	2019-03-28	2024-04-02	住友重機械工業株式会社	ショベル
CN113200966B (zh) *	2021-04-06	2022-07-22	深圳大学	一种呋喹替尼衍生物、药物组合物和用途
GB202211142D0 (en) *	2022-07-29	2022-09-14	Macfarlan Smith Ltd	Polymorphs, co-crystals and solvates of fruquintinib, processes for the preparation and use thereof
WO2024245409A1 (zh) *	2023-06-02	2024-12-05	成都苑东生物制药股份有限公司	一种vegfr抑制剂的水合物，其晶型及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7829574B2 (en)	2008-05-09	2010-11-09	Hutchison Medipharma Enterprises Limited	Substituted quinazoline compounds and their use in treating angiogenesis-related diseases
CN101575333B (zh) *	2008-05-09	2011-06-22	和记黄埔医药（上海）有限公司	一种喹唑啉衍生物及其医药用途
CN105461702A (zh) *	2014-09-10	2016-04-06	和记黄埔医药（上海）有限公司	6-(6,7-二甲氧基喹唑啉-4-基氧基)-n,2-二甲基苯并呋喃-3-甲酰胺晶型

2014
- 2014-09-10 CN CN201410456350.9A patent/CN105461702A/zh active Pending
2015
- 2015-09-07 CA CA2958666A patent/CA2958666C/en active Active
- 2015-09-07 CN CN201911135376.2A patent/CN111018846B/zh active Active
- 2015-09-07 MX MX2017002913A patent/MX370791B/es active IP Right Grant
- 2015-09-07 UA UAA201702962A patent/UA120371C2/uk unknown
- 2015-09-07 PT PT158395194T patent/PT3191475T/pt unknown
- 2015-09-07 PL PL15839519T patent/PL3191475T3/pl unknown
- 2015-09-07 DK DK15839519.4T patent/DK3191475T3/da active
- 2015-09-07 SM SM20200511T patent/SMT202000511T1/it unknown
- 2015-09-07 HR HRP20201501TT patent/HRP20201501T1/hr unknown
- 2015-09-07 KR KR1020177006544A patent/KR20170042662A/ko not_active Ceased
- 2015-09-07 SI SI201531358T patent/SI3191475T1/sl unknown
- 2015-09-07 WO PCT/CN2015/089035 patent/WO2016037550A1/en not_active Ceased
- 2015-09-07 HU HUE15839519A patent/HUE050580T2/hu unknown
- 2015-09-07 US US15/510,631 patent/US10519142B2/en active Active
- 2015-09-07 EP EP15839519.4A patent/EP3191475B1/en active Active
- 2015-09-07 AU AU2015316010A patent/AU2015316010B2/en active Active
- 2015-09-07 BR BR112017004000-0A patent/BR112017004000B1/pt active IP Right Grant
- 2015-09-07 EA EA201790275A patent/EA034730B1/ru unknown
- 2015-09-07 LT LTEP15839519.4T patent/LT3191475T/lt unknown
- 2015-09-07 ES ES15839519T patent/ES2819242T3/es active Active
- 2015-09-07 KR KR1020197004333A patent/KR102221722B1/ko active Active
- 2015-09-07 SG SG11201701544UA patent/SG11201701544UA/en unknown
- 2015-09-07 RS RS20201083A patent/RS60829B1/sr unknown
- 2015-09-07 CN CN201580047368.6A patent/CN106604919B/zh active Active
- 2015-09-07 PE PE2017000426A patent/PE20170661A1/es unknown
- 2015-09-07 JP JP2017513447A patent/JP6655608B2/ja active Active
- 2015-09-07 MY MYPI2017700610A patent/MY176618A/en unknown
- 2015-09-10 TW TW104129900A patent/TWI718105B/zh active
2017
- 2017-02-16 IL IL250647A patent/IL250647B/en active IP Right Grant
- 2017-02-21 ZA ZA2017/01320A patent/ZA201701320B/en unknown
- 2017-03-07 CL CL2017000540A patent/CL2017000540A1/es unknown
- 2017-03-09 PH PH12017500451A patent/PH12017500451A1/en unknown
2018
- 2018-12-03 JP JP2018226597A patent/JP2019065019A/ja not_active Withdrawn
2019
- 2019-11-08 US US16/678,760 patent/US11046674B2/en active Active
2020
- 2020-09-25 CY CY20201100909T patent/CY1123892T1/el unknown
2021
- 2021-05-20 US US17/303,114 patent/US11958838B2/en active Active
2024
- 2024-02-27 US US18/588,874 patent/US20240279208A1/en active Pending
- 2024-12-16 FR FR24C1055C patent/FR24C1055I2/fr active Active
- 2024-12-17 NO NO2024061C patent/NO2024061I1/no unknown
- 2024-12-17 FI FIC20240047C patent/FIC20240047I1/fi unknown
- 2024-12-18 NL NL301307C patent/NL301307I2/nl unknown
- 2024-12-18 HU HUS2400047C patent/HUS2400047I1/hu unknown
- 2024-12-19 LT LTPA2024541C patent/LTPA2024541I1/lt unknown

Also Published As

Publication number	Publication date
JP6655608B2 (ja)	2020-02-26
SG11201701544UA (en)	2017-03-30
EP3191475A4 (en)	2018-10-03
US11958838B2 (en)	2024-04-16
LTPA2024541I1 (nl)	2025-01-10
CN111018846A (zh)	2020-04-17
FR24C1055I2 (fr)	2025-10-10
BR112017004000A2 (pt)	2017-12-05
BR112017004000B1 (pt)	2023-10-24
MX370791B (es)	2020-01-08
DK3191475T3 (da)	2020-09-28
HRP20201501T1 (hr)	2020-12-25
US20200140420A1 (en)	2020-05-07
HUS2400047I1 (hu)	2025-01-28
AU2015316010A8 (en)	2017-05-11
CY1123892T1 (el)	2022-03-24
FR24C1055I1 (fr)	2025-02-21
CA2958666C (en)	2020-10-06
HUE050580T2 (hu)	2020-12-28
NO2024061I1 (no)	2024-12-17
WO2016037550A1 (en)	2016-03-17
KR102221722B1 (ko)	2021-03-03
US20240279208A1 (en)	2024-08-22
EP3191475B1 (en)	2020-07-29
IL250647A0 (en)	2017-04-30
TWI718105B (zh)	2021-02-11
ES2819242T3 (es)	2021-04-15
EA201790275A1 (ru)	2017-10-31
US10519142B2 (en)	2019-12-31
PT3191475T (pt)	2020-09-04
PH12017500451A1 (en)	2017-07-31
RS60829B1 (sr)	2020-10-30
NZ729884A (en)	2020-09-25
PL3191475T3 (pl)	2021-01-11
LT3191475T (lt)	2020-10-12
UA120371C2 (uk)	2019-11-25
IL250647B (en)	2020-11-30
CN111018846B (zh)	2023-06-06
EP3191475A1 (en)	2017-07-19
EA034730B1 (ru)	2020-03-13
JP2019065019A (ja)	2019-04-25
AU2015316010B2 (en)	2018-06-14
CA2958666A1 (en)	2016-03-17
CN106604919A (zh)	2017-04-26
MX2017002913A (es)	2017-06-06
AU2015316010A1 (en)	2017-04-27
KR20190018056A (ko)	2019-02-20
SI3191475T1 (sl)	2021-02-26
US20170283399A1 (en)	2017-10-05
TW201609715A (zh)	2016-03-16
MY176618A (en)	2020-08-18
CN106604919B (zh)	2019-11-15
HK1231479A1 (zh)	2017-12-22
CL2017000540A1 (es)	2017-09-15
US20210276983A1 (en)	2021-09-09
US11046674B2 (en)	2021-06-29
KR20170042662A (ko)	2017-04-19
PE20170661A1 (es)	2017-05-18
SMT202000511T1 (it)	2020-11-10
JP2017526710A (ja)	2017-09-14
ZA201701320B (en)	2020-07-29
CN105461702A (zh)	2016-04-06
FIC20240047I1 (fi)	2024-12-17

Publication	Publication Date	Title
DK3183051T3 (da)	2020-06-02	Væske-til-luftmembranenergivekslere
DK4242916T3 (da)	2025-12-15	Forstøver
DK3134402T3 (da)	2020-07-20	4-amino-imidazoquinolinforbindelser
DK3006072T3 (da)	2021-10-25	Karadgang
DK3211743T3 (da)	2019-12-16	Ø-til-netværk-omskiftningsfremgangsmåde
DK3222714T3 (da)	2019-12-09	Phytasemutanter
DK3119396T3 (da)	2021-05-31	Muscarinreceptoragonister
EP3230438C0 (en)	2024-12-04	N-GLYCOSYLATION
NL301307I2 (nl)	2024-12-31	fruquintinib
EP4011484C0 (en)	2025-09-24	CARBONIC ANHYDRASE OF THERMOVIBRIO AMMONIFICANS
DK3183340T3 (da)	2019-08-19	Termolabile exonukleaser
DE112015001664A5 (de)	2016-12-29	Betätigungsaktuator
DK3154703T3 (da)	2020-11-16	Fuldkappe-snekkecentrifuge
DE112015005041A5 (de)	2017-08-31	Gargerätevorrichtung
DK3110439T3 (da)	2019-05-13	Pcsk9-vacciner
DE102014000623A8 (de)	2016-10-13	Halbhohlnietelement
DK3009858T3 (da)	2021-08-09	Skyradar
DE202014005655U8 (de)	2014-11-13	llluminationsvorrichtung
DE112015001633A5 (de)	2017-02-23	Betätigungsaktuator
DK3447493T3 (da)	2020-08-17	Proteinrettede ortologer
ES1133830Y (es)	2015-02-12	Columbario
DE112015005055A5 (de)	2017-08-03	Gargerätevorrichtung
DK3091875T3 (da)	2019-10-14	Vipbar taburet
DK3191825T3 (da)	2019-05-06	Kreatininbiosensor
FI10894U1 (fi)	2015-06-11	Putkieristyskouru