MXPA02011899A - Agentes secretagogos de hormona de crecimiento. - Google Patents
Agentes secretagogos de hormona de crecimiento.Info
- Publication number
- MXPA02011899A MXPA02011899A MXPA02011899A MXPA02011899A MXPA02011899A MX PA02011899 A MXPA02011899 A MX PA02011899A MX PA02011899 A MXPA02011899 A MX PA02011899A MX PA02011899 A MXPA02011899 A MX PA02011899A MX PA02011899 A MXPA02011899 A MX PA02011899A
- Authority
- MX
- Mexico
- Prior art keywords
- growth hormone
- hormone secretagogues
- growth
- secretion deficiency
- hormone secretion
- Prior art date
Links
- 239000003324 growth hormone secretagogue Substances 0.000 title 1
- 102000018997 Growth Hormone Human genes 0.000 abstract 3
- 108010051696 Growth Hormone Proteins 0.000 abstract 3
- 239000000122 growth hormone Substances 0.000 abstract 3
- 230000007812 deficiency Effects 0.000 abstract 2
- 230000028327 secretion Effects 0.000 abstract 2
- 206010053759 Growth retardation Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003028 elevating effect Effects 0.000 abstract 1
- 231100000001 growth retardation Toxicity 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 230000036470 plasma concentration Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Nutrition Science (AREA)
- Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Abstract
La invencion se refiere al compuesto de la formula (I) que son utiles para elevar el nivel en plasma de la hormona de crecimiento en un mamifero asi como para el tratamiento de la deficiencia de secrecion de hormona de crecimiento, retardo de crecimiento en ninos y trastornos metabolicos asociados con la deficiencia de secrecion de hormona de crecimiento.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21132600P | 2000-06-13 | 2000-06-13 | |
| US23492800P | 2000-09-26 | 2000-09-26 | |
| PCT/EP2001/006717 WO2001096300A1 (en) | 2000-06-13 | 2001-06-13 | Growth hormone secretagogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02011899A true MXPA02011899A (es) | 2003-04-22 |
Family
ID=26906052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02011899A MXPA02011899A (es) | 2000-06-13 | 2001-06-13 | Agentes secretagogos de hormona de crecimiento. |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US6861409B2 (es) |
| EP (1) | EP1289951B1 (es) |
| JP (2) | JP3522265B2 (es) |
| KR (1) | KR100825109B1 (es) |
| CN (1) | CN1232507C (es) |
| AR (1) | AR029941A1 (es) |
| AT (3) | ATE362472T1 (es) |
| AU (2) | AU2001266066B2 (es) |
| BG (3) | BG66130B1 (es) |
| BR (1) | BRPI0111591B8 (es) |
| CA (1) | CA2407659C (es) |
| CY (2) | CY1107710T1 (es) |
| CZ (2) | CZ305279B6 (es) |
| DE (3) | DE60112753T2 (es) |
| DK (3) | DK1524272T3 (es) |
| ES (3) | ES2292900T3 (es) |
| FR (1) | FR19C1044I2 (es) |
| HU (1) | HU229233B1 (es) |
| IL (2) | IL153067A0 (es) |
| MX (1) | MXPA02011899A (es) |
| NL (1) | NL300999I2 (es) |
| NO (1) | NO323873B1 (es) |
| NZ (1) | NZ522280A (es) |
| PL (1) | PL216676B1 (es) |
| PT (2) | PT1524272E (es) |
| RU (1) | RU2270198C2 (es) |
| SK (1) | SK287169B6 (es) |
| TW (2) | TW200831076A (es) |
| WO (1) | WO2001096300A1 (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1524272T3 (da) * | 2000-06-13 | 2007-09-03 | Zentaris Gmbh | Væksthormonsekretionsfremmere |
| CU23157A1 (es) * | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| US7034050B2 (en) * | 2004-04-28 | 2006-04-25 | Romano Deghenghi | Pseudopeptides growth hormone secretagogues |
| US8138218B2 (en) * | 2005-07-22 | 2012-03-20 | Ipsen Pharma S.A.S. | Growth hormone secretagogues |
| EP1757290A1 (en) | 2005-08-16 | 2007-02-28 | Zentaris GmbH | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors |
| GB0603295D0 (en) * | 2006-02-18 | 2006-03-29 | Ardana Bioscience Ltd | Methods and kits |
| CU23558A1 (es) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
| US7763707B2 (en) * | 2006-03-13 | 2010-07-27 | Liat Mintz | Use of ghrelin splice variant for treating cachexia and/or anorexia and/or anorexia-cachexia and/or malnutrition and/or lipodystrophy and/or muscle wasting and/or appetite-stimulation |
| ES2604943T3 (es) | 2007-02-09 | 2017-03-10 | Ocera Therapeutics, Inc. | Moduladores macrocíclicos del receptor de la grelina y procedimientos de uso de los mismos |
| EP2103602A1 (en) | 2008-03-17 | 2009-09-23 | AEterna Zentaris GmbH | Novel 1,2,4-triazole derivatives and process of manufacturing thereof |
| US8431642B2 (en) * | 2008-06-09 | 2013-04-30 | Exxonmobil Chemical Patents Inc. | Polyolefin adhesive compositions and articles made therefrom |
| EP2431035A1 (en) | 2010-09-16 | 2012-03-21 | Æterna Zentaris GmbH | Novel Triazole Derivatives with Improved Receptor Activity and Bioavailability Properties as Ghrelin Antagonists of Growth Hormone Secretagogue Receptors |
| US8747922B2 (en) | 2012-09-19 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods and compositions for increasing sex steroids and growth hormones |
| US10300101B2 (en) | 2012-09-19 | 2019-05-28 | Quality IP Holdings, LLC | Methods and compositions for enhancing or maintaining fertility |
| US8747921B2 (en) | 2012-09-19 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods for improving health in humans |
| US9198889B2 (en) | 2012-09-19 | 2015-12-01 | Quality IP Holdings, LLC | Methods for treating post-traumatic stress disorder |
| US10292957B2 (en) | 2012-09-20 | 2019-05-21 | Quality IP Holdings, LLC | Compositions and methods for treating fibromyalgia |
| US8715752B2 (en) | 2012-09-20 | 2014-05-06 | Quality Ip Holdings, Inc. | Compositions for increasing human growth hormone levels |
| US8747923B2 (en) | 2012-09-20 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods for improving health in canines |
| US9066953B2 (en) | 2012-09-20 | 2015-06-30 | Quality IP Holdings, LLC | Methods for increasing endurance and fat metabolism in humans |
| JP6262661B2 (ja) | 2012-10-24 | 2018-01-17 | 第一三共株式会社 | 筋萎縮性側索硬化症治療剤 |
| CN105330720A (zh) * | 2014-06-06 | 2016-02-17 | 深圳翰宇药业股份有限公司 | 一种制备马昔瑞林的方法 |
| HRP20220317T1 (hr) * | 2015-09-21 | 2022-05-13 | Lumos Pharma Inc. | Otkrivanje i liječenje nedostatka hormona rasta |
| US10894072B2 (en) | 2017-02-13 | 2021-01-19 | IP Quality Holdings, LLC | Compositions and methods for treating fibromyalgia |
| US10288629B1 (en) | 2017-12-19 | 2019-05-14 | Aeterna Zentaris, Inc. | Method of assessing growth hormone deficiency in humans by a macimorelin containing composition |
| KR102635025B1 (ko) | 2020-07-22 | 2024-02-07 | 아에테르나 젠타리스 게엠베하 | 마시모렐린을 사용하여 소아 환자의 성장 호르몬 결핍증을 진단하는 스크리닝 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880778A (en) * | 1986-05-12 | 1989-11-14 | Eastman Kodak Company | Combinations having synergistic growth hormone releasing activity and methods for use thereof |
| ATE122357T1 (de) * | 1988-01-28 | 1995-05-15 | Polygen Holding Corp | Polypeptide mit hormonwachstumsbefreiender wirkung. |
| US5536814A (en) * | 1993-09-27 | 1996-07-16 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| CA2176140A1 (en) * | 1993-11-24 | 1995-06-01 | Meng Hsin Chen | Indolyl group containing compounds and the use thereof to promote the release of growth hormone(s) |
| US5798337A (en) * | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
| US6025471A (en) * | 1998-06-03 | 2000-02-15 | Deghenghi; Romano | Diazaspiro, azepino and azabicyclo therapeutic peptides |
| DK1524272T3 (da) * | 2000-06-13 | 2007-09-03 | Zentaris Gmbh | Væksthormonsekretionsfremmere |
-
2001
- 2001-06-13 DK DK05075086T patent/DK1524272T3/da active
- 2001-06-13 DE DE60112753T patent/DE60112753T2/de not_active Expired - Lifetime
- 2001-06-13 AT AT05075086T patent/ATE362472T1/de active
- 2001-06-13 IL IL15306701A patent/IL153067A0/xx unknown
- 2001-06-13 PT PT05075086T patent/PT1524272E/pt unknown
- 2001-06-13 ES ES03075950T patent/ES2292900T3/es not_active Expired - Lifetime
- 2001-06-13 SK SK1756-2002A patent/SK287169B6/sk not_active IP Right Cessation
- 2001-06-13 CN CNB018104916A patent/CN1232507C/zh not_active Expired - Lifetime
- 2001-06-13 MX MXPA02011899A patent/MXPA02011899A/es active IP Right Grant
- 2001-06-13 WO PCT/EP2001/006717 patent/WO2001096300A1/en not_active Ceased
- 2001-06-13 RU RU2002135312/04A patent/RU2270198C2/ru not_active IP Right Cessation
- 2001-06-13 ES ES05075086T patent/ES2288724T3/es not_active Expired - Lifetime
- 2001-06-13 CZ CZ2011-585A patent/CZ305279B6/cs not_active IP Right Cessation
- 2001-06-13 DE DE60130025T patent/DE60130025T2/de not_active Expired - Lifetime
- 2001-06-13 CA CA2407659A patent/CA2407659C/en not_active Expired - Lifetime
- 2001-06-13 AR ARP010102827A patent/AR029941A1/es active IP Right Grant
- 2001-06-13 AT AT01943504T patent/ATE302181T1/de active
- 2001-06-13 AT AT03075950T patent/ATE370119T1/de active
- 2001-06-13 DK DK01943504T patent/DK1289951T3/da active
- 2001-06-13 ES ES01943504T patent/ES2250416T3/es not_active Expired - Lifetime
- 2001-06-13 NZ NZ522280A patent/NZ522280A/en not_active IP Right Cessation
- 2001-06-13 DE DE60128494T patent/DE60128494T2/de not_active Expired - Lifetime
- 2001-06-13 PL PL363081A patent/PL216676B1/pl unknown
- 2001-06-13 BR BRPI0111591A patent/BRPI0111591B8/pt not_active IP Right Cessation
- 2001-06-13 CZ CZ20024095A patent/CZ303173B6/cs not_active IP Right Cessation
- 2001-06-13 KR KR1020027016614A patent/KR100825109B1/ko not_active Expired - Lifetime
- 2001-06-13 AU AU2001266066A patent/AU2001266066B2/en not_active Expired
- 2001-06-13 PT PT03075950T patent/PT1344773E/pt unknown
- 2001-06-13 EP EP01943504A patent/EP1289951B1/en not_active Expired - Lifetime
- 2001-06-13 JP JP2002510444A patent/JP3522265B2/ja not_active Expired - Lifetime
- 2001-06-13 DK DK03075950T patent/DK1344773T3/da active
- 2001-06-13 AU AU6606601A patent/AU6606601A/xx active Pending
- 2001-06-13 HU HU0302026A patent/HU229233B1/hu active IP Right Revival
- 2001-06-13 US US09/880,498 patent/US6861409B2/en not_active Expired - Lifetime
- 2001-08-01 TW TW097111056A patent/TW200831076A/zh unknown
- 2001-08-01 TW TW090114317A patent/TWI305529B/zh not_active IP Right Cessation
-
2002
- 2002-11-24 IL IL153067A patent/IL153067A/en active IP Right Grant
- 2002-12-09 NO NO20025893A patent/NO323873B1/no not_active IP Right Cessation
- 2002-12-12 BG BG107379A patent/BG66130B1/bg unknown
-
2003
- 2003-06-02 JP JP2003156884A patent/JP4932132B2/ja not_active Expired - Lifetime
-
2004
- 2004-05-04 US US10/837,620 patent/US7297681B2/en not_active Expired - Lifetime
-
2007
- 2007-08-07 CY CY20071101051T patent/CY1107710T1/el unknown
- 2007-11-08 CY CY20071101443T patent/CY1107793T1/el unknown
-
2010
- 2010-07-21 BG BG10110708A patent/BG66216B1/bg unknown
- 2010-10-18 BG BG10110771A patent/BG66217B1/bg unknown
-
2019
- 2019-07-05 NL NL300999C patent/NL300999I2/nl unknown
- 2019-07-08 FR FR19C1044C patent/FR19C1044I2/fr active Active
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