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MX9705648A - Empleo dermatologico de derivados de vitamina d. - Google Patents

Empleo dermatologico de derivados de vitamina d.

Info

Publication number
MX9705648A
MX9705648A MX9705648A MX9705648A MX9705648A MX 9705648 A MX9705648 A MX 9705648A MX 9705648 A MX9705648 A MX 9705648A MX 9705648 A MX9705648 A MX 9705648A MX 9705648 A MX9705648 A MX 9705648A
Authority
MX
Mexico
Prior art keywords
cycloalkyl
lower alkyl
vitamin
hydroxy
derivatives
Prior art date
Application number
MX9705648A
Other languages
English (en)
Other versions
MXPA97005648A (es
Inventor
Pierre Barbier
Marc Muller
Josef Stadlwieser
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX9705648A publication Critical patent/MX9705648A/es
Publication of MXPA97005648A publication Critical patent/MXPA97005648A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Derivados de vitamina D de la formula I (Ver Formula) X es =CH2 o H,H; Y es una fraccion -CH(CH3)=(A)n-C(O)-OR1 (a) -CH(CH3)-CH2O-C(O)-R2 (b) o -C(O)-OR1 (c); A es -CH=CH- o CH2-CH2- R1 es alquilo inferior, cicloalquilo, cicloalquilo, cicloalquilmetilo, -CH2R3 o -CH2CH2R3, R2 es alquilo inferior, cicloalquilo o R3; R3 es hidroxi-alquilo inferior, hidroxi-cicloalquilo o trifluo-rometil-hidroxi-alquilo inferior; n es 0 o 1; y el enlace de trazos en el anillo pentagonal es opcional,; pueden utilizarse en el tratamiento de condiciones dermatologicas, en particular trastornos de queratinizacion.
MXPA/A/1997/005648A 1995-01-26 1997-07-25 Empleo dermatologico de derivados de vitamina d MXPA97005648A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95101030.5 1995-01-26
EP95101030 1995-01-26
PCT/EP1996/000176 WO1996022776A1 (en) 1995-01-26 1996-01-17 Dermatological use of vitamin d derivatives

Publications (2)

Publication Number Publication Date
MX9705648A true MX9705648A (es) 1997-10-31
MXPA97005648A MXPA97005648A (es) 1998-07-03

Family

ID=

Also Published As

Publication number Publication date
HUP9800697A2 (hu) 1998-07-28
EA199700263A1 (ru) 1998-02-26
AR003107A1 (es) 1998-07-08
IL116825A0 (en) 1996-05-14
CO4700475A1 (es) 1998-12-29
US5827883A (en) 1998-10-27
JPH10502940A (ja) 1998-03-17
DE69633106T2 (de) 2005-09-15
PL321638A1 (en) 1997-12-22
DE69633106D1 (de) 2004-09-16
CA2210884A1 (en) 1996-08-01
ES2225865T3 (es) 2005-03-16
ZA96452B (en) 1996-07-26
FI973124A7 (fi) 1997-07-25
EP0805682B1 (en) 2004-08-11
PE28297A1 (es) 1997-08-20
MA23783A1 (fr) 1996-10-01
JP2908566B2 (ja) 1999-06-21
KR19980701671A (ko) 1998-06-25
CN1168103A (zh) 1997-12-17
WO1996022776A1 (en) 1996-08-01
NO973455L (no) 1997-09-25
FI973124A0 (fi) 1997-07-25
BR9606856A (pt) 1997-11-25
EP0805682A1 (en) 1997-11-12
CZ238497A3 (en) 1997-11-12
ATE273010T1 (de) 2004-08-15
NO973455D0 (no) 1997-07-25
AU4536796A (en) 1996-08-14
FI973124L (fi) 1997-07-25
TR199700694T1 (xx) 1998-02-21
HUP9800697A3 (en) 1999-03-01

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