MX2008010804A - Derivados de rapamicina para tratar neuroblastoma. - Google Patents
Derivados de rapamicina para tratar neuroblastoma.Info
- Publication number
- MX2008010804A MX2008010804A MX2008010804A MX2008010804A MX2008010804A MX 2008010804 A MX2008010804 A MX 2008010804A MX 2008010804 A MX2008010804 A MX 2008010804A MX 2008010804 A MX2008010804 A MX 2008010804A MX 2008010804 A MX2008010804 A MX 2008010804A
- Authority
- MX
- Mexico
- Prior art keywords
- rapamycin derivatives
- treating neuroblastoma
- neuroblastoma
- treating
- rapamycin
- Prior art date
Links
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical class C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title abstract 2
- 206010029260 Neuroblastoma Diseases 0.000 title 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 229940088679 drug related substance Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Un derivado de rapamicina para uso en el tratamiento de neuroblastoma, opcionalmente en combinación con una segunda sustancia de fármaco.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0603782.4A GB0603782D0 (en) | 2006-02-24 | 2006-02-24 | Organic compounds |
| PCT/EP2007/001551 WO2007096174A1 (en) | 2006-02-24 | 2007-02-22 | Rapamycin derivatives for treating neuroblastoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008010804A true MX2008010804A (es) | 2008-10-31 |
Family
ID=36178746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008010804A MX2008010804A (es) | 2006-02-24 | 2007-02-22 | Derivados de rapamicina para tratar neuroblastoma. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090023768A1 (es) |
| EP (1) | EP1988894A1 (es) |
| JP (1) | JP2009527520A (es) |
| KR (1) | KR20080100346A (es) |
| CN (1) | CN101389337A (es) |
| AU (1) | AU2007217705A1 (es) |
| BR (1) | BRPI0708160A2 (es) |
| CA (1) | CA2642243A1 (es) |
| GB (1) | GB0603782D0 (es) |
| MX (1) | MX2008010804A (es) |
| RU (1) | RU2008137723A (es) |
| WO (1) | WO2007096174A1 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2589383A1 (en) | 2011-11-06 | 2013-05-08 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin | FKBP subtype-specific rapamycin analogue for use in treatment of diseases |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102268015B (zh) * | 2011-08-30 | 2013-08-28 | 成都摩尔生物医药有限公司 | 一种依维莫司的合成方法 |
| UY37900A (es) * | 2017-09-26 | 2019-04-30 | Novartis Ag | Nuevos derivados de rapamicina |
| AU2019409366B2 (en) | 2018-12-18 | 2022-10-27 | Novartis Ag | Rapamycin derivatives |
| PT3947392T (pt) * | 2019-03-26 | 2024-05-14 | Novartis Ag | Derivados de rapamicina contendo 1,1-dióxido de isotiazolidina e 1,4-butano sultona e seus usos |
| CN113181117B (zh) * | 2021-03-22 | 2022-08-26 | 沈阳药科大学 | 一种紫草素和蒽环类化疗药共载脂质体及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0210101A (pt) * | 2001-06-01 | 2004-06-08 | Wyeth Corp | Combinações antineoplásticas |
| AU2003241359A1 (en) * | 2002-05-06 | 2003-11-11 | Functional Genetics, Inc. | Mammalian genes involed in rapamycin resistance and tumorgenesis: annexin xiii genes |
| WO2004004644A2 (en) * | 2002-07-05 | 2004-01-15 | Beth Israel Deaconess Medical Center | Combination of mtor inhibitor and a tyrosine kinase inhibitor for the treatment of neoplasms |
| GB0217777D0 (en) * | 2002-07-31 | 2002-09-11 | Novartis Ag | Organic compounds |
| US20060099676A1 (en) * | 2002-08-15 | 2006-05-11 | Limin Li | Mammalian genes involved in rapamycin resistance and tumorgenesis: rapr6 genes |
| GB0327840D0 (en) * | 2003-12-01 | 2003-12-31 | Novartis Ag | Organic compounds |
-
2006
- 2006-02-22 US US12/280,031 patent/US20090023768A1/en not_active Abandoned
- 2006-02-24 GB GBGB0603782.4A patent/GB0603782D0/en not_active Ceased
-
2007
- 2007-02-22 KR KR1020087020610A patent/KR20080100346A/ko not_active Withdrawn
- 2007-02-22 CN CNA2007800066878A patent/CN101389337A/zh active Pending
- 2007-02-22 MX MX2008010804A patent/MX2008010804A/es not_active Application Discontinuation
- 2007-02-22 AU AU2007217705A patent/AU2007217705A1/en not_active Abandoned
- 2007-02-22 BR BRPI0708160-0A patent/BRPI0708160A2/pt not_active Application Discontinuation
- 2007-02-22 RU RU2008137723/14A patent/RU2008137723A/ru not_active Application Discontinuation
- 2007-02-22 JP JP2008555703A patent/JP2009527520A/ja active Pending
- 2007-02-22 WO PCT/EP2007/001551 patent/WO2007096174A1/en not_active Ceased
- 2007-02-22 EP EP07703541A patent/EP1988894A1/en not_active Withdrawn
- 2007-02-22 CA CA002642243A patent/CA2642243A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2589383A1 (en) | 2011-11-06 | 2013-05-08 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin | FKBP subtype-specific rapamycin analogue for use in treatment of diseases |
| WO2013064703A2 (en) | 2011-11-06 | 2013-05-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Fkbp subtype-specific rapamycin analogue for use in treatment of diseases |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007217705A1 (en) | 2007-08-30 |
| BRPI0708160A2 (pt) | 2011-05-17 |
| GB0603782D0 (en) | 2006-04-05 |
| JP2009527520A (ja) | 2009-07-30 |
| KR20080100346A (ko) | 2008-11-17 |
| RU2008137723A (ru) | 2010-03-27 |
| EP1988894A1 (en) | 2008-11-12 |
| CN101389337A (zh) | 2009-03-18 |
| CA2642243A1 (en) | 2007-08-30 |
| WO2007096174A1 (en) | 2007-08-30 |
| US20090023768A1 (en) | 2009-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |