The Python GUI API Project
The
PyGUI project is developing a cross-platform GUI API for Python.
Version 1.3 of PyGUI was just released.
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This version includes two implementations, one for MacOS X built on Carbon, and one for X11 built on Gtk. Python 2.3 or later is required. The MacOS X version should work on a standard installation of MacPython. The X11 version requires PyGtk-2.2.0 or later, plus the Gtk library itself (Gtk+-2.2 or later)"