Nephrotic Syndrome in Children

Nephrotic syndrome is an important childhood glomerular disease. In recent decades, there have been exciting breakthroughs in our understanding of the disease pathogenesis and in the advancement of medical care for this condition. Such developments include the identification of anti-nephrin autoantibodies, the discovery of pathogenic variants, the use of biologics to optimise disease control and the emerging potential of gene therapies. This Topical Collection focuses on both the translational and clinical science of idiopathic nephrotic syndrome among children and young people. Submissions relating to other disease entities presenting as nephrotic syndrome are also welcome. Kazumoto Iijima and Eugene Yu-hin Chan serve as guest editors of this article collection. Our aims are to summarise current knowledge and present cutting-edge research findings in the field, with the ultimate goal of transforming and improving patient care in the years ahead.