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HCV/Oxidative Stress and Liver Disease

  • Conference proceedings
  • © 2003

Overview

Editors:
  1. Kiwamu Okita

    1. Department of Gastroenterology and Hepatology, Yamaguchi University School of Medicine, Ube, Yamaguchi, Japan

  • Including information on new aspects of oxidative stress and liver disease

  • 1449 Accesses

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About this book

Since the discovery of superoxide dismutase more than three decades ago, there has been rapid growth in the knowledge of oxidative stress and disease. This volume containing the proceedings of the 13th Yamaguchi Symposium on Liver Disease includes discussion of the direct cellular effects of hepatitis C virus (HCV) proteins on hepatocytes and reviews evidence that oxidative stress caused primarily by the HCV core protein plays a key role in disease pathogenesis. Also included are chapters on new aspects of oxidative stress and liver disease such as carbon monoxide as a regulator of liver microcirculation, hepatic iron accumulation and the incidence of hepatocellular carcinoma, and oxidative stress in the absence of inflammation in hepatocarcinogenesis. This collection of papers from the Yamaguchi Symposium creates a valuable reference resource for physicians and hepatologists.

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Table of contents (11 papers)

  1. Front Matter

    Pages II-XI
    Download chapter PDF

  2. Alcohol-HCV Interactions in Transgenic Mice Expressing Viral Proteins in the Liver

    • Michiari Okuda, Lori A. Showalter, Kazuhiro Otani, Michael R. Beard, Shu-Yuan Xiao, Stanley M. Lemon et al.
    Pages 1-7

  3. Role of Core Protein-Induced Oxidative Stress in the Pathogenesis of Hepatitis C

    • Steven A. Weinman, Michiari Okuda, Kui Li, Lori A. Showalter, Kazuhiro Otani, Stanley M. Lemon et al.
    Pages 8-18

  4. Hepatitis C Virus Core-Mediated Alteration of Gene Expression and Signal Transduction in the Host Cell

    • Kazuyoshi Ohkawa, Atsushi Hosui, Yutaka Sasaki, Norio Hayashi
    Pages 19-31

  5. Signals Induced by HCV Proteins

    • Motoyuki Otsuka, Naoya Kato, Hiroyoshi Taniguchi, Hideo Yoshida, Yasushi Shiratori, Masao Omata
    Pages 32-47

  6. Role of Hepatitis C Virus in Hepatocarcinogenesis: Oxidative Stress in the Absence of Inflammation

    • Kazuhiko Koike, Kyoji Moriya
    Pages 48-57

  7. Reduced Chemical Hepatocarcinogenesis in Interferon-γ Receptor Knockout Mice

    • Mitsuru Matsuda, Yasunari Nakamoto, Shuichi Kaneko, Kenichi Kobayashi
    Pages 58-66

  8. Fewer Somatic Mutations of Mitochondrial DNA in Noncancerous Liver Tissue of Patients with Hepatocellular Carcinoma Respond to Interferon Therapy

    • Shuhei Nishiguchi, Manabu Nishikawa, Masayasu Inoue, Susumu Shiomi, Akihiro Tamori, Daiki Habu et al.
    Pages 67-75

  9. Hepatic Iron Staining in Chronic Hepatitis C Patients with Low HCV RNA Levels as a Predictive Marker for Interferon Therapy

    • Tatsuya Ide, Fuyuhiko Akiyoshi, Michio Sata, Yasuyo Uchimura, Hiroshi Suzuki, Kyuichi Tanikawa
    Pages 76-82

  10. Hepatic Iron Accumulation and Incidence of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C

    • Namiki Izumi, Yasuhiro Asahina, Osamu Noguchi, Masakatsu Uchihara, Sukenobu Kawamura, Kaoru Tsuchiya et al.
    Pages 83-90

  11. Carbon Monoxide as a Gaseous Regulator of Liver Microcirculation

    • Makoto Suematsu, Satoshi Kashiwagi
    Pages 91-95

  12. Tamoxifen-Induced Nonalcoholic Steatohepatitis

    • Toshiji Saibara, Yasuhiro Ogawa, Nan Xu, Yoshihisa Nemoto, Masafumi Ono, Akihiko Wakatsuki et al.
    Pages 96-104

  13. Back Matter

    Pages 105-107
    Download chapter PDF
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Editors and Affiliations

  • Department of Gastroenterology and Hepatology, Yamaguchi University School of Medicine, Ube, Yamaguchi, Japan

    Kiwamu Okita

Accessibility Information

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Bibliographic Information

  • Book Title: HCV/Oxidative Stress and Liver Disease

  • Editors: Kiwamu Okita

  • DOI: https://doi.org/10.1007/978-4-431-67005-6

  • Publisher: Springer Tokyo

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Japan 2003

  • Hardcover ISBN: 978-4-431-70324-2Published: 02 December 2002

  • Softcover ISBN: 978-4-431-67007-0Published: 18 January 2013

  • eBook ISBN: 978-4-431-67005-6Published: 09 March 2013

  • Edition Number: 1

  • Number of Pages: XI, 107

  • Topics: Oxidative Stress, Hepatology

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